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The map label for this gene is nuoI1 [H]

Identifier: 218883727

GI number: 218883727

Start: 388827

End: 389228

Strand: Reverse

Name: nuoI1 [H]

Synonym: DKAM_0416

Alternate gene names: 218883727

Gene position: 389228-388827 (Counterclockwise)

Preceding gene: 218883728

Following gene: 218883726

Centisome position: 28.51

GC content: 46.27

Gene sequence:

>402_bases
ATGGGGAAGCCGAAGATACTCAATCTAGTATTAAAGAACCTGGCTAGTAAGCCAGCTACCATACAGTATCCCAAGGAACC
GACCCCTGTGGAGCCCGATTACAGGGGGAGGCATTACGCGGATCTAGGTAAATGCACTGGCTGCTCTCTCTGTTCTATTG
AGTGCCCTGCTGACGCAATAAAGATGACGCCTATACCCAGCGGGTATGATGTACCGAAGAGCAATCCCAGGAAGATATAT
CCATTAATAGACTATGGTAAGTGTGTTTACTGTTATCGTTGTATAACCGTGTGCCCATTTAATGCTTATATCTCCACAAA
CGAGTACAGGCTTGCAGATACCACTATGCATAATTCATCTGAGCTAAGTCTTTCCACGCTTAAGAAGGGTGGTCCCGGAT
GA

Upstream 100 bases:

>100_bases
CTCTCGACCCATGTATTTCATGTATGGAGAGAGTCACTGTTGTGGACTTGGAGAAGAATATCGTGTACAAGGTTTCCTTG
AAGGAGCTGGGTGGTGGGAA

Downstream 100 bases:

>100_bases
TCATCGATATGGTTGCACCCGTAATAATACTCGTATACACTATATCAATAATGCTCGTCTTCATAAGGGCTGTAAAGGGA
CCCACAATAGGGGACCAAGT

Product: NADH-ubiquinone oxidoreductase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I 1; NDH-1 subunit I 1 [H]

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MGKPKILNLVLKNLASKPATIQYPKEPTPVEPDYRGRHYADLGKCTGCSLCSIECPADAIKMTPIPSGYDVPKSNPRKIY
PLIDYGKCVYCYRCITVCPFNAYISTNEYRLADTTMHNSSELSLSTLKKGGPG

Sequences:

>Translated_133_residues
MGKPKILNLVLKNLASKPATIQYPKEPTPVEPDYRGRHYADLGKCTGCSLCSIECPADAIKMTPIPSGYDVPKSNPRKIY
PLIDYGKCVYCYRCITVCPFNAYISTNEYRLADTTMHNSSELSLSTLKKGGPG
>Mature_132_residues
GKPKILNLVLKNLASKPATIQYPKEPTPVEPDYRGRHYADLGKCTGCSLCSIECPADAIKMTPIPSGYDVPKSNPRKIYP
LIDYGKCVYCYRCITVCPFNAYISTNEYRLADTTMHNSSELSLSTLKKGGPG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI4505371, Length=114, Percent_Identity=32.4561403508772, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14668; Mature: 14537

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
6.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKPKILNLVLKNLASKPATIQYPKEPTPVEPDYRGRHYADLGKCTGCSLCSIECPADAI
CCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
KMTPIPSGYDVPKSNPRKIYPLIDYGKCVYCYRCITVCPFNAYISTNEYRLADTTMHNSS
EECCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCCCCCEEECCCEEEEECCCCCCC
ELSLSTLKKGGPG
CCCHHHHCCCCCC
>Mature Secondary Structure 
GKPKILNLVLKNLASKPATIQYPKEPTPVEPDYRGRHYADLGKCTGCSLCSIECPADAI
CCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCE
KMTPIPSGYDVPKSNPRKIYPLIDYGKCVYCYRCITVCPFNAYISTNEYRLADTTMHNSS
EECCCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHHCCCCCEEECCCEEEEECCCCCCC
ELSLSTLKKGGPG
CCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]