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The map label for this gene is bglA [H]

Identifier: 218883564

GI number: 218883564

Start: 233729

End: 234922

Strand: Direct

Name: bglA [H]

Synonym: DKAM_0253

Alternate gene names: 218883564

Gene position: 233729-234922 (Clockwise)

Preceding gene: 218883562

Following gene: 218883571

Centisome position: 17.12

GC content: 47.49

Gene sequence:

>1194_bases
ATGTATAATGACTGGTGGTATTGGGAGACAACTGGAAGGCTAAGAGTTAAATCAGGAAAGGCATGCAATCACTGGGAACT
CTACCGTGAAGACATAGAGTTGATGAGTAGGCTCGGCTACGATGGATACAGGTTCTCCATAGAGTGGAGCAGGATATTCC
CCCAGGAGAACTTGTTCGATGAGAGGGCTTTAAACAGGTACGTGGAGATCGTGGAGCTCCTAAGAAAGCACGGGATAACC
CCAGTGGTCACACTACACCATTTCACGAGCCCCAAATGGTTTATTGATAAAGGGGGATGGCTTAGAGAGGAGAACATATC
CTACTTCAGGAGGTATGTTGAAGCAGTTGTGGATAGTGTTAAAGGGGTGAACTACTGGGTTGTCTTCAACGAGCCAAATG
TTTACATTCTCCAGGGCTACATAATGGGCGCGTGGCCCCCTGGCTACAAAAGTCTGAAGATAGCTGATAAGGCAGCAGTG
AACATCGTGAAGGCTTATAAGGAGGCCTACGAGGTCCTCAAAGGAAGGGGGAAAGTAGGGGTAGCCCAGAACCTGATATC
CTTCAAGCCGGCTAGTGATGGTAGACGGGATCTCAATGCATGCGAGAAAGCTAGGGAGGCATATAACCACGGGTTCCTGA
AAGGGGTACTCCAGGGAGAATATGTTTCACTGAGAGGGATAAAGAGGATTGAGGAGAGCGATATGGACTTCATCGGCGTC
AACTATTATAGTGGGTTCGTGGTTAAACACGTGTTCAACCCCTTGAAGATGTTCATGGATGTGAGGCCTCTTGACACAGG
GTTGTGGACCACTATGGGGTACTGTATATACCCCAGGGGGATCTATGAGGTGACGAGAGAAGTCTATGATAGATACAGGA
GGGATATCATTATCACGGAGAACGGTGTAGCCGTTAAAGATGATGAGTTAAGGATACTCTCGATTGTGAGGCACCTCCAA
TATGTCTACAAGGCTTTATCCGAGGGTATACCTATACACGGCTACTATTACTGGAGCTTCATGGATAACTATGAATGGGA
TAAGGGCTTCGAGCAGAGGTTCGGCTTGTTCGAGGTAGACTACTCGACGTTCGAGAGGAAGCCGAGGAGAAGCGCGTATG
TCTATAGCGAGATAGCAAGAACTAAGAGGATAAGCGATGAGCTACTGGAGAAGTATGGTGAAAAACAGAGTTAA

Upstream 100 bases:

>100_bases
TAGATATTCTAGATAATAAGAGGAGATACCCTTGATAGAATTTCCCCGGGATTTCACGTTTGGAACAGCAACGGCTTCCC
ACCAGATTGAAGGAGACAAC

Downstream 100 bases:

>100_bases
CCAAGACTACTTCTTCCCAGCTAGAAATTCCTTCGCTACATTATATGCTTTCAAGGCATACATGAGGGCGGGCCCGCCGC
CCATGCATACAGCTACCTTT

Product: glycoside hydrolase, family 1

Products: NA

Alternate protein names: Beta-D-glucoside glucohydrolase; Cellobiase; Gentiobiase [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MYNDWWYWETTGRLRVKSGKACNHWELYREDIELMSRLGYDGYRFSIEWSRIFPQENLFDERALNRYVEIVELLRKHGIT
PVVTLHHFTSPKWFIDKGGWLREENISYFRRYVEAVVDSVKGVNYWVVFNEPNVYILQGYIMGAWPPGYKSLKIADKAAV
NIVKAYKEAYEVLKGRGKVGVAQNLISFKPASDGRRDLNACEKAREAYNHGFLKGVLQGEYVSLRGIKRIEESDMDFIGV
NYYSGFVVKHVFNPLKMFMDVRPLDTGLWTTMGYCIYPRGIYEVTREVYDRYRRDIIITENGVAVKDDELRILSIVRHLQ
YVYKALSEGIPIHGYYYWSFMDNYEWDKGFEQRFGLFEVDYSTFERKPRRSAYVYSEIARTKRISDELLEKYGEKQS

Sequences:

>Translated_397_residues
MYNDWWYWETTGRLRVKSGKACNHWELYREDIELMSRLGYDGYRFSIEWSRIFPQENLFDERALNRYVEIVELLRKHGIT
PVVTLHHFTSPKWFIDKGGWLREENISYFRRYVEAVVDSVKGVNYWVVFNEPNVYILQGYIMGAWPPGYKSLKIADKAAV
NIVKAYKEAYEVLKGRGKVGVAQNLISFKPASDGRRDLNACEKAREAYNHGFLKGVLQGEYVSLRGIKRIEESDMDFIGV
NYYSGFVVKHVFNPLKMFMDVRPLDTGLWTTMGYCIYPRGIYEVTREVYDRYRRDIIITENGVAVKDDELRILSIVRHLQ
YVYKALSEGIPIHGYYYWSFMDNYEWDKGFEQRFGLFEVDYSTFERKPRRSAYVYSEIARTKRISDELLEKYGEKQS
>Mature_397_residues
MYNDWWYWETTGRLRVKSGKACNHWELYREDIELMSRLGYDGYRFSIEWSRIFPQENLFDERALNRYVEIVELLRKHGIT
PVVTLHHFTSPKWFIDKGGWLREENISYFRRYVEAVVDSVKGVNYWVVFNEPNVYILQGYIMGAWPPGYKSLKIADKAAV
NIVKAYKEAYEVLKGRGKVGVAQNLISFKPASDGRRDLNACEKAREAYNHGFLKGVLQGEYVSLRGIKRIEESDMDFIGV
NYYSGFVVKHVFNPLKMFMDVRPLDTGLWTTMGYCIYPRGIYEVTREVYDRYRRDIIITENGVAVKDDELRILSIVRHLQ
YVYKALSEGIPIHGYYYWSFMDNYEWDKGFEQRFGLFEVDYSTFERKPRRSAYVYSEIARTKRISDELLEKYGEKQS

Specific function: Can Hydrolyze Salicin, Cellobiose, And Probably Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=418, Percent_Identity=28.4688995215311, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI32481206, Length=425, Percent_Identity=27.7647058823529, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI110681710, Length=416, Percent_Identity=26.6826923076923, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI24497614, Length=377, Percent_Identity=26.525198938992, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI28376633, Length=395, Percent_Identity=24.3037974683544, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789070, Length=418, Percent_Identity=28.2296650717703, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI2367174, Length=387, Percent_Identity=27.6485788113695, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI2367270, Length=409, Percent_Identity=25.9168704156479, Blast_Score=104, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17552856, Length=414, Percent_Identity=30.1932367149758, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17539390, Length=437, Percent_Identity=28.8329519450801, Blast_Score=154, Evalue=9e-38,
Organism=Drosophila melanogaster, GI21356577, Length=440, Percent_Identity=27.5, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017736
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.21 [H]

Molecular weight: Translated: 47054; Mature: 47054

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNDWWYWETTGRLRVKSGKACNHWELYREDIELMSRLGYDGYRFSIEWSRIFPQENLFD
CCCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCHHH
ERALNRYVEIVELLRKHGITPVVTLHHFTSPKWFIDKGGWLREENISYFRRYVEAVVDSV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHH
KGVNYWVVFNEPNVYILQGYIMGAWPPGYKSLKIADKAAVNIVKAYKEAYEVLKGRGKVG
CCCEEEEEECCCCEEEEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
VAQNLISFKPASDGRRDLNACEKAREAYNHGFLKGVLQGEYVSLRGIKRIEESDMDFIGV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCEEEE
NYYSGFVVKHVFNPLKMFMDVRPLDTGLWTTMGYCIYPRGIYEVTREVYDRYRRDIIITE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHCCCCHHHHHHHHHHHHHHCCEEEEC
NGVAVKDDELRILSIVRHLQYVYKALSEGIPIHGYYYWSFMDNYEWDKGFEQRFGLFEVD
CCEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHCCEEEEC
YSTFERKPRRSAYVYSEIARTKRISDELLEKYGEKQS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYNDWWYWETTGRLRVKSGKACNHWELYREDIELMSRLGYDGYRFSIEWSRIFPQENLFD
CCCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCCCCHHH
ERALNRYVEIVELLRKHGITPVVTLHHFTSPKWFIDKGGWLREENISYFRRYVEAVVDSV
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHH
KGVNYWVVFNEPNVYILQGYIMGAWPPGYKSLKIADKAAVNIVKAYKEAYEVLKGRGKVG
CCCEEEEEECCCCEEEEEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCC
VAQNLISFKPASDGRRDLNACEKAREAYNHGFLKGVLQGEYVSLRGIKRIEESDMDFIGV
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCEEEE
NYYSGFVVKHVFNPLKMFMDVRPLDTGLWTTMGYCIYPRGIYEVTREVYDRYRRDIIITE
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHCCCCHHHHHHHHHHHHHHCCEEEEC
NGVAVKDDELRILSIVRHLQYVYKALSEGIPIHGYYYWSFMDNYEWDKGFEQRFGLFEVD
CCEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHHCCEEEEC
YSTFERKPRRSAYVYSEIARTKRISDELLEKYGEKQS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8277941 [H]