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The map label for this gene is appC [H]

Identifier: 218883544

GI number: 218883544

Start: 216343

End: 217239

Strand: Direct

Name: appC [H]

Synonym: DKAM_0233

Alternate gene names: 218883544

Gene position: 216343-217239 (Clockwise)

Preceding gene: 218883543

Following gene: 218883545

Centisome position: 15.85

GC content: 45.71

Gene sequence:

>897_bases
ATGAACAGTATTGAGGCAAATATTAGGGGTGCAGCATACCTTGTCAGGAAACAGTTTAGGAAGACGAGGTTTAAAACAGG
TTTAGCAATAGTGTTGGTGATCACCATTCTAGCTCTACTCTCGCCAATAATAGCTCCGTTCCCAGAGGAGGGCCTAGGCT
ATATACCGGAGAACGCTGTAGCGAAGGCCAGGCTTCCGCCGAATCCAGTCAATATATTTGGAACCGATACGAGGGGGAGA
GACTTATTTTCTAGAGTGCTCTTTGGCGCCGGATCAGCATTGGTTGAAATATTAATCGTCGTTCTCACGAGTCTCTCTAT
AGGTATAATCATAGGGGTTTCGGCAGCGTACTTTAAAGGTGTCGTGGAACACGTATTGAACTACCTTATTGAATTATTTG
TAAGTGTACCAGCAATAATAATAGCCCTGGCTTTGAGACTGGCAATAGGACCCGGCTTATATGTGGTCATACTCGGGTTG
ATTACAACATGGTGGTCATGGTATGCTAGGGTTACCTATATATATGCCAGAAGCATTGTTGAAATGGATTACGTAGTATT
AGCAAGGCTCAGTGGGCTGAACAGTTTAAAGATAATTTATAGGCATGTATTAAGGAACACAATTCCACCCGTCCTAGTAC
AGGCTGTGACAGATATGGGGAGTGTCCTCTTAGAGGCCACCTCCATAAACTTCATAGGGCTGGGCGTCCCCTTAAACTCG
CCCGAATGGGGGGTTATAATGCTTGAAGGCCTCCCAGTTATTACTATCGCGCCATGGATAACCATGTTCCCCGGCATCTT
TCTATTGATCACTGCTCTCGGATTCAGCTTAATAGGTGATAGCCTAAGAGAGGAACTGGATCCACGGATGAGGAGGAGGT
GGAGGCTGTGGTTCTAG

Upstream 100 bases:

>100_bases
GGCTAGCAATAGGCTTAATCACTGTAGTAGCTGTCTTCTACCTCGTGGTTAACACACTAACTGATATAATTCAGGCACTC
GTAGATCCAAGGGTGAGGCT

Downstream 100 bases:

>100_bases
CCGTTAAAGCAGTGGACTTGAAGATAGGTTATATGGATGAGGAGGAAAAGATTTACTGGGCTGTTAGAGGCGTTAGCTTC
CAGGTGAGTGAGAGCGAGAT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNSIEANIRGAAYLVRKQFRKTRFKTGLAIVLVITILALLSPIIAPFPEEGLGYIPENAVAKARLPPNPVNIFGTDTRGR
DLFSRVLFGAGSALVEILIVVLTSLSIGIIIGVSAAYFKGVVEHVLNYLIELFVSVPAIIIALALRLAIGPGLYVVILGL
ITTWWSWYARVTYIYARSIVEMDYVVLARLSGLNSLKIIYRHVLRNTIPPVLVQAVTDMGSVLLEATSINFIGLGVPLNS
PEWGVIMLEGLPVITIAPWITMFPGIFLLITALGFSLIGDSLREELDPRMRRRWRLWF

Sequences:

>Translated_298_residues
MNSIEANIRGAAYLVRKQFRKTRFKTGLAIVLVITILALLSPIIAPFPEEGLGYIPENAVAKARLPPNPVNIFGTDTRGR
DLFSRVLFGAGSALVEILIVVLTSLSIGIIIGVSAAYFKGVVEHVLNYLIELFVSVPAIIIALALRLAIGPGLYVVILGL
ITTWWSWYARVTYIYARSIVEMDYVVLARLSGLNSLKIIYRHVLRNTIPPVLVQAVTDMGSVLLEATSINFIGLGVPLNS
PEWGVIMLEGLPVITIAPWITMFPGIFLLITALGFSLIGDSLREELDPRMRRRWRLWF
>Mature_298_residues
MNSIEANIRGAAYLVRKQFRKTRFKTGLAIVLVITILALLSPIIAPFPEEGLGYIPENAVAKARLPPNPVNIFGTDTRGR
DLFSRVLFGAGSALVEILIVVLTSLSIGIIIGVSAAYFKGVVEHVLNYLIELFVSVPAIIIALALRLAIGPGLYVVILGL
ITTWWSWYARVTYIYARSIVEMDYVVLARLSGLNSLKIIYRHVLRNTIPPVLVQAVTDMGSVLLEATSINFIGLGVPLNS
PEWGVIMLEGLPVITIAPWITMFPGIFLLITALGFSLIGDSLREELDPRMRRRWRLWF

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=258, Percent_Identity=35.2713178294574, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=28.2608695652174, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1789889, Length=240, Percent_Identity=32.0833333333333, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789964, Length=222, Percent_Identity=31.981981981982, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787549, Length=279, Percent_Identity=27.5985663082437, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787498, Length=277, Percent_Identity=27.4368231046931, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788505, Length=228, Percent_Identity=29.3859649122807, Blast_Score=95, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32955; Mature: 32955

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSIEANIRGAAYLVRKQFRKTRFKTGLAIVLVITILALLSPIIAPFPEEGLGYIPENAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AKARLPPNPVNIFGTDTRGRDLFSRVLFGAGSALVEILIVVLTSLSIGIIIGVSAAYFKG
EECCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVEHVLNYLIELFVSVPAIIIALALRLAIGPGLYVVILGLITTWWSWYARVTYIYARSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMDYVVLARLSGLNSLKIIYRHVLRNTIPPVLVQAVTDMGSVLLEATSINFIGLGVPLNS
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
PEWGVIMLEGLPVITIAPWITMFPGIFLLITALGFSLIGDSLREELDPRMRRRWRLWF
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCC
>Mature Secondary Structure
MNSIEANIRGAAYLVRKQFRKTRFKTGLAIVLVITILALLSPIIAPFPEEGLGYIPENAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
AKARLPPNPVNIFGTDTRGRDLFSRVLFGAGSALVEILIVVLTSLSIGIIIGVSAAYFKG
EECCCCCCCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVEHVLNYLIELFVSVPAIIIALALRLAIGPGLYVVILGLITTWWSWYARVTYIYARSIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMDYVVLARLSGLNSLKIIYRHVLRNTIPPVLVQAVTDMGSVLLEATSINFIGLGVPLNS
HHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
PEWGVIMLEGLPVITIAPWITMFPGIFLLITALGFSLIGDSLREELDPRMRRRWRLWF
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]