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The map label for this gene is pyrK [H]

Identifier: 218883413

GI number: 218883413

Start: 86014

End: 86823

Strand: Direct

Name: pyrK [H]

Synonym: DKAM_0099

Alternate gene names: 218883413

Gene position: 86014-86823 (Clockwise)

Preceding gene: 218883412

Following gene: 218883414

Centisome position: 6.3

GC content: 59.14

Gene sequence:

>810_bases
ATGAAGGAAGACCTGAACGAGCAGGACTACTACCTTGAGGTGGAGGGTCCCCACGTCTCCAGGCACTGGAGGCCAGGCCA
GTTCGTGATAATCATGACCCACGAGAGGGGTGAGCGCGTCCCCATATCGGTCGCAACTATTAACGGTGGTAGGGTGGGGA
TGTTCATTAAGAAACTAGGAAAGACCTCGGTTGAGCTCTACAGAGATTTCAAGGTGGGGAGCTCGCTGTACGCTGTAGCG
GGCCCTCTAGGTAGGCCCCTGAAGCTGGAGAGCTACGGGACAGTCGTGCTGGCGTCAGACGCCGTCTGCGGCCACGCCGA
GCAGCTGGGTCTCGCCCAGGAGCTCGCCAAGCTGGGCAACAAGGTGATATCGATCCAGACCTTCAAGACCGAGAAGGAGG
TGTACCCCGAGAAGTACTTGGCCAAGAAGTATGTTGACGAGTACTTCATAACTACACTAGACGGCACGGCCGGGTATAAG
GGGCACTACATCGACTTACTGAGGGAGCTCTTGGCTCGCAGGGAGGTGAAGGCCATCTTCGCCGGGGGTGCGCTGGCCAA
CCTCAAGAAGCTCGCCGAGGCGACGGCGGGGCTGGACGTGAGGGTCTACGCTCTCGTTAGGACGATAATGGTGGACGGGA
CGGGGATGTGCGGGTCTTGTAGAGTCAGGTACAACGGGGTGATAGCCTACGCGTGTAGAGACGGCCCCTGGTTTGACGCC
AGGCTGGTCGACTGGGACGACGTCCTGAGGAGGGACGCGAGGTTCAAGAAGGTCGAGAAGATCGCACTGGACAAGTACCT
GGCGAGGTGA

Upstream 100 bases:

>100_bases
TGTACATAGCCGAACGTCTACTACATATTCATTTATATATCCTTCCAATGGTAATTGTTAGGTAGGTTGAACGAAAGGTG
TTAACATGTTCCGTGTAACA

Downstream 100 bases:

>100_bases
GCTGTCTTGTCCCGAGTGGTCAAGAAGAGGTTTACACCTAAGGTCCTGCCCGTAAGCGAGAGGCTGAGGAGCTTCGGCGA
GGTGGTCTTGGGCTACGACT

Product: ferredoxin-NADP(+) reductase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MKEDLNEQDYYLEVEGPHVSRHWRPGQFVIIMTHERGERVPISVATINGGRVGMFIKKLGKTSVELYRDFKVGSSLYAVA
GPLGRPLKLESYGTVVLASDAVCGHAEQLGLAQELAKLGNKVISIQTFKTEKEVYPEKYLAKKYVDEYFITTLDGTAGYK
GHYIDLLRELLARREVKAIFAGGALANLKKLAEATAGLDVRVYALVRTIMVDGTGMCGSCRVRYNGVIAYACRDGPWFDA
RLVDWDDVLRRDARFKKVEKIALDKYLAR

Sequences:

>Translated_269_residues
MKEDLNEQDYYLEVEGPHVSRHWRPGQFVIIMTHERGERVPISVATINGGRVGMFIKKLGKTSVELYRDFKVGSSLYAVA
GPLGRPLKLESYGTVVLASDAVCGHAEQLGLAQELAKLGNKVISIQTFKTEKEVYPEKYLAKKYVDEYFITTLDGTAGYK
GHYIDLLRELLARREVKAIFAGGALANLKKLAEATAGLDVRVYALVRTIMVDGTGMCGSCRVRYNGVIAYACRDGPWFDA
RLVDWDDVLRRDARFKKVEKIALDKYLAR
>Mature_269_residues
MKEDLNEQDYYLEVEGPHVSRHWRPGQFVIIMTHERGERVPISVATINGGRVGMFIKKLGKTSVELYRDFKVGSSLYAVA
GPLGRPLKLESYGTVVLASDAVCGHAEQLGLAQELAKLGNKVISIQTFKTEKEVYPEKYLAKKYVDEYFITTLDGTAGYK
GHYIDLLRELLARREVKAIFAGGALANLKKLAEATAGLDVRVYALVRTIMVDGTGMCGSCRVRYNGVIAYACRDGPWFDA
RLVDWDDVLRRDARFKKVEKIALDKYLAR

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 30146; Mature: 30146

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDLNEQDYYLEVEGPHVSRHWRPGQFVIIMTHERGERVPISVATINGGRVGMFIKKLG
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHC
KTSVELYRDFKVGSSLYAVAGPLGRPLKLESYGTVVLASDAVCGHAEQLGLAQELAKLGN
CHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
KVISIQTFKTEKEVYPEKYLAKKYVDEYFITTLDGTAGYKGHYIDLLRELLARREVKAIF
EEEEEEEECCHHHHCHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
AGGALANLKKLAEATAGLDVRVYALVRTIMVDGTGMCGSCRVRYNGVIAYACRDGPWFDA
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCCCCE
RLVDWDDVLRRDARFKKVEKIALDKYLAR
EEECHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEDLNEQDYYLEVEGPHVSRHWRPGQFVIIMTHERGERVPISVATINGGRVGMFIKKLG
CCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCHHHHHHHHC
KTSVELYRDFKVGSSLYAVAGPLGRPLKLESYGTVVLASDAVCGHAEQLGLAQELAKLGN
CHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHCC
KVISIQTFKTEKEVYPEKYLAKKYVDEYFITTLDGTAGYKGHYIDLLRELLARREVKAIF
EEEEEEEECCHHHHCHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
AGGALANLKKLAEATAGLDVRVYALVRTIMVDGTGMCGSCRVRYNGVIAYACRDGPWFDA
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEECCCCCCCE
RLVDWDDVLRRDARFKKVEKIALDKYLAR
EEECHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]