Click here to switch to the map view.

The map label for this gene is gpt [H]

Identifier: 218883372

GI number: 218883372

Start: 54550

End: 55101

Strand: Direct

Name: gpt [H]

Synonym: DKAM_0058

Alternate gene names: 218883372

Gene position: 54550-55101 (Clockwise)

Preceding gene: 218883369

Following gene: 218883375

Centisome position: 4.0

GC content: 42.75

Gene sequence:

>552_bases
ATGGTGCCTCAGAAGGTTAAGACTAGGTATATATCCTGGAGCATGCTGCATGAATCACTGAAGAACCTAGCTGAGAAAAT
AAGTAGCGAATACACTGCAGACACTATTATAGCGATAGCGAAGGGCGGGTTGATACCGGCCAGGATCCTCGTGGATCTAC
TTGGAATAGATGAAATGGGCTTTATAGAGGTTAAATTTTACAGGGGGATAGCGGAAACACGTGAGAAACCATATGTTACC
TTCACAGCTCTTCCCCAGCTAGATAATAAGAGAATCATCATTGTAGACGATATAGTTGATACCGGCAGGACCCTACAAGT
AGCCGCTGATGTGTTAAGTAGATTCAAATATAGAGATATGAAATTCGCCACACTCTATGTGAAGCCGTGGAGCACTATAA
TGCCCGACTATTATAGTGAAATCGTGGATGAATGGATTATATTTCCATGGGAAATATGTGAATCCATTAGGGAGAATGCT
GAATTAAAAGGAGTGGATGTGGGGGGAATACTTGACTACTGTAAGAGGAAGCACGGTTCCCAGGGTCTTTGA

Upstream 100 bases:

>100_bases
CGGATAGTACTCCTCCAGTTACAAAGACGTATTTAACCATGGTGCCCGCTTCAACATAATAAATACATGGCTTAAAAATA
TTTAATTAACAGGGGGATAG

Downstream 100 bases:

>100_bases
GTTAGAGTCGGCTTGGAAACCAGAATCGTGATCACGGTTCAACACTGAAGTATAGCCTCTTCTTATTCTTACCCTTGTTC
TCGACTCTAAGTAATTTGAT

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MVPQKVKTRYISWSMLHESLKNLAEKISSEYTADTIIAIAKGGLIPARILVDLLGIDEMGFIEVKFYRGIAETREKPYVT
FTALPQLDNKRIIIVDDIVDTGRTLQVAADVLSRFKYRDMKFATLYVKPWSTIMPDYYSEIVDEWIIFPWEICESIRENA
ELKGVDVGGILDYCKRKHGSQGL

Sequences:

>Translated_183_residues
MVPQKVKTRYISWSMLHESLKNLAEKISSEYTADTIIAIAKGGLIPARILVDLLGIDEMGFIEVKFYRGIAETREKPYVT
FTALPQLDNKRIIIVDDIVDTGRTLQVAADVLSRFKYRDMKFATLYVKPWSTIMPDYYSEIVDEWIIFPWEICESIRENA
ELKGVDVGGILDYCKRKHGSQGL
>Mature_183_residues
MVPQKVKTRYISWSMLHESLKNLAEKISSEYTADTIIAIAKGGLIPARILVDLLGIDEMGFIEVKFYRGIAETREKPYVT
FTALPQLDNKRIIIVDDIVDTGRTLQVAADVLSRFKYRDMKFATLYVKPWSTIMPDYYSEIVDEWIIFPWEICESIRENA
ELKGVDVGGILDYCKRKHGSQGL

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 20971; Mature: 20971

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPQKVKTRYISWSMLHESLKNLAEKISSEYTADTIIAIAKGGLIPARILVDLLGIDEMG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCC
FIEVKFYRGIAETREKPYVTFTALPQLDNKRIIIVDDIVDTGRTLQVAADVLSRFKYRDM
EEEEHHHHCHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
KFATLYVKPWSTIMPDYYSEIVDEWIIFPWEICESIRENAELKGVDVGGILDYCKRKHGS
EEEEEEECCCHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
QGL
CCC
>Mature Secondary Structure
MVPQKVKTRYISWSMLHESLKNLAEKISSEYTADTIIAIAKGGLIPARILVDLLGIDEMG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCC
FIEVKFYRGIAETREKPYVTFTALPQLDNKRIIIVDDIVDTGRTLQVAADVLSRFKYRDM
EEEEHHHHCHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
KFATLYVKPWSTIMPDYYSEIVDEWIIFPWEICESIRENAELKGVDVGGILDYCKRKHGS
EEEEEEECCCHHHCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
QGL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA