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The map label for this gene is tsr [C]

Identifier: 218533032

GI number: 218533032

Start: 5522351

End: 5524348

Strand: Reverse

Name: tsr [C]

Synonym: Mchl_5156

Alternate gene names: 218533032

Gene position: 5524348-5522351 (Counterclockwise)

Preceding gene: 218533033

Following gene: 218533031

Centisome position: 95.61

GC content: 67.67

Gene sequence:

>1998_bases
ATGAAAACCGGTATTCGCACGCGTCTCTACGGCGGATTTTCAGCATTGGTCGCCTTGTCCTGCGGTATGGGGGCGTTCTC
CTACACGCAGCTCGACAGTCTCGACGAGATGTTCCGTGCGCGGGCTCAGCTCGAATCCGCAGCCCGAACGCTCTACACCA
TCAATGGTCTGTCCGACCGGTTGATCGGTCAGGCTGCCCAGTACAGGCTGACCCAGGCCGCCGACTACACGACCGGAATG
TTCGCGTCGTTGGACTCGATCCGGCAGGGCTCCGAGAAGCTCATTGCGAGCACACCGAGCGCGGAGCGGCGCGCGGCCTA
TGAGCGGCTTCGGGATCAGTCCACCGATCTCGGCAAGGCGCTGCCGAAGCTGGTCGAGCTCGGCGCGCAGATCCGCGAGA
ACCGGGCCGGCGTTTACGCCAACGGCGACGACCTGACCAAGGCCTCCGGCGTCCTCGTCGCCCAGTTGCGGGCCACGGGC
CAGGATGCGGTGATCGCTCAGGCCGTGGAGGTCGAGCGCACGCTGCTTCTGTTCCGCATCATGAACTGGCGCTTCCTCGC
CACCAAGGATCCGAAGGGCCGTGCCCTCTCGGCCAACGCCTTCGGCAACGCCGAGGCGGCCCTGGCGAAACTGAAGGCTC
TCGATCTCACCGCCGCCGACCAAGAGACGGCAAAGCTCGTCGGCGAGACCCTGAACCGGCTCAACAAGAGCATCGTCGCC
GCCTCCCAGGCCATCGTCGAAAGTGAAACGTTCTTTGAGGAGACGCTGAAGCCGAGGGTGGACGGCATCAACGCGACGGG
CGTGTCGGTGCGCAGCAAGCTCGAGACGGCGCTTCAGGACGGAGTCGAGCAGAGCAACGCCCTGATGACGCGGGCGAAGA
CCGTCCAGCTCATCCTGCTCGGCCTGATCCTGGCGACCGGCGCCGCCCTGGCCTTCCTGATCGCCCGCAGCCTGATCCGC
CCGATCTCGGGGATGACCGCCGCGATGAGCCGCCTCGCCGCGGGCGAGACGGCCATCGAGGTGCCGTCTCGGGACGCGGT
GGACGAGATGGGCCGGATGGCCGAGGCGGTTGAGGTGTTCCGGCAGAACGCCGTGGCCCGCATCGAACTCGAGGCGGAGC
GGGTGGCCCAACAATCCGCCCGCCAGCGCCGGGCCGATCGTGTCGATGGGCTGGTGCGCGGTTTCGAGGAAAAGATCGCC
GCCTCCATCGCCATCGTGACCTCGGCGGCGACCGAACTGGACAGCACCGCCCGGTCGATGACGCAGGTCGCCGACAACAC
CAACGGGCAGGCGGTCGCCTCCAGCGCCGCGGCCGAGGAAGCCACTGTCAACGTGCAGACGGTCGCCGCAGCGGCCGAGG
AGATGGTCGCCTCGCTCAGCGAGATCGAGCGGCGCGTCCAGCAATCCAACGACGTGGCGGGTCATGCCAGCCACGAGGCC
CGGACGACCACCGACTCGATGAGCCATCTCAGCCGCGCGGCCGAGAAGATCGGCGAGGCGGTGACGATGATCTCCGGGCT
CGCGAGCCAGACGAACCTGCTCGCGCTCAACGCCACCATCGAGGCGGCGCGGGCCGGCGAGGCGGGCCGCGGCTTTGCCG
TCGTCGCCACCGAGGTCAAGGAACTCGCGGCGCAAACCGCCCGCACCACGGAGGCGATCTCCGATCAGGTCAGTGCGATC
CAAACCGCCTCGACCCAGGCACTCGGTGCGATCCAGCAGATTGGCCGGACCATCGTCTCGGTCAACGACATCACCGCCTC
GATCGCGGCAACCGTCGTACAGCAGACCGCCGCGACCAATGAGATTGCCCGCAACGCCTCCGAGGCAGCCCGCGGCACCC
AGGACGTGTCGATGAGCGTCGCGCAGGTACAGGCGCTGTCGAGCGAGACCGGATCGGCCGCGCAGCAGGTGATGATGGCC
TCGTCCGAGCTTTCGACCCAGTCCGAAAACGTGCGGCGCGAGGTCGAGGACTTCCTCGCCGCAATCCGGGCCGCCTGA

Upstream 100 bases:

>100_bases
CAACTGCCGACTTTTGAGGCTTCGACCATCGTAAGTTAAGATCCCGGAAAGGCGTCATTCGGCACAACGAGACAACATTT
GTTCGCTCGACGGCAGTCTG

Downstream 100 bases:

>100_bases
CGGCCCTGCCGAGCGGACGGATTAGCGGTCCACCCCTCAGCGTCTACCAACGGCCGGCTCCGCCACGGGGCCGAACGTTG
CCAAATGAGACGCACGGACC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MKTGIRTRLYGGFSALVALSCGMGAFSYTQLDSLDEMFRARAQLESAARTLYTINGLSDRLIGQAAQYRLTQAADYTTGM
FASLDSIRQGSEKLIASTPSAERRAAYERLRDQSTDLGKALPKLVELGAQIRENRAGVYANGDDLTKASGVLVAQLRATG
QDAVIAQAVEVERTLLLFRIMNWRFLATKDPKGRALSANAFGNAEAALAKLKALDLTAADQETAKLVGETLNRLNKSIVA
ASQAIVESETFFEETLKPRVDGINATGVSVRSKLETALQDGVEQSNALMTRAKTVQLILLGLILATGAALAFLIARSLIR
PISGMTAAMSRLAAGETAIEVPSRDAVDEMGRMAEAVEVFRQNAVARIELEAERVAQQSARQRRADRVDGLVRGFEEKIA
ASIAIVTSAATELDSTARSMTQVADNTNGQAVASSAAAEEATVNVQTVAAAAEEMVASLSEIERRVQQSNDVAGHASHEA
RTTTDSMSHLSRAAEKIGEAVTMISGLASQTNLLALNATIEAARAGEAGRGFAVVATEVKELAAQTARTTEAISDQVSAI
QTASTQALGAIQQIGRTIVSVNDITASIAATVVQQTAATNEIARNASEAARGTQDVSMSVAQVQALSSETGSAAQQVMMA
SSELSTQSENVRREVEDFLAAIRAA

Sequences:

>Translated_665_residues
MKTGIRTRLYGGFSALVALSCGMGAFSYTQLDSLDEMFRARAQLESAARTLYTINGLSDRLIGQAAQYRLTQAADYTTGM
FASLDSIRQGSEKLIASTPSAERRAAYERLRDQSTDLGKALPKLVELGAQIRENRAGVYANGDDLTKASGVLVAQLRATG
QDAVIAQAVEVERTLLLFRIMNWRFLATKDPKGRALSANAFGNAEAALAKLKALDLTAADQETAKLVGETLNRLNKSIVA
ASQAIVESETFFEETLKPRVDGINATGVSVRSKLETALQDGVEQSNALMTRAKTVQLILLGLILATGAALAFLIARSLIR
PISGMTAAMSRLAAGETAIEVPSRDAVDEMGRMAEAVEVFRQNAVARIELEAERVAQQSARQRRADRVDGLVRGFEEKIA
ASIAIVTSAATELDSTARSMTQVADNTNGQAVASSAAAEEATVNVQTVAAAAEEMVASLSEIERRVQQSNDVAGHASHEA
RTTTDSMSHLSRAAEKIGEAVTMISGLASQTNLLALNATIEAARAGEAGRGFAVVATEVKELAAQTARTTEAISDQVSAI
QTASTQALGAIQQIGRTIVSVNDITASIAATVVQQTAATNEIARNASEAARGTQDVSMSVAQVQALSSETGSAAQQVMMA
SSELSTQSENVRREVEDFLAAIRAA
>Mature_665_residues
MKTGIRTRLYGGFSALVALSCGMGAFSYTQLDSLDEMFRARAQLESAARTLYTINGLSDRLIGQAAQYRLTQAADYTTGM
FASLDSIRQGSEKLIASTPSAERRAAYERLRDQSTDLGKALPKLVELGAQIRENRAGVYANGDDLTKASGVLVAQLRATG
QDAVIAQAVEVERTLLLFRIMNWRFLATKDPKGRALSANAFGNAEAALAKLKALDLTAADQETAKLVGETLNRLNKSIVA
ASQAIVESETFFEETLKPRVDGINATGVSVRSKLETALQDGVEQSNALMTRAKTVQLILLGLILATGAALAFLIARSLIR
PISGMTAAMSRLAAGETAIEVPSRDAVDEMGRMAEAVEVFRQNAVARIELEAERVAQQSARQRRADRVDGLVRGFEEKIA
ASIAIVTSAATELDSTARSMTQVADNTNGQAVASSAAAEEATVNVQTVAAAAEEMVASLSEIERRVQQSNDVAGHASHEA
RTTTDSMSHLSRAAEKIGEAVTMISGLASQTNLLALNATIEAARAGEAGRGFAVVATEVKELAAQTARTTEAISDQVSAI
QTASTQALGAIQQIGRTIVSVNDITASIAATVVQQTAATNEIARNASEAARGTQDVSMSVAQVQALSSETGSAAQQVMMA
SSELSTQSENVRREVEDFLAAIRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=386, Percent_Identity=26.9430051813472, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788194, Length=224, Percent_Identity=31.25, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1788195, Length=187, Percent_Identity=37.9679144385027, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787690, Length=228, Percent_Identity=34.2105263157895, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789453, Length=157, Percent_Identity=35.031847133758, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 70206; Mature: 70206

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGIRTRLYGGFSALVALSCGMGAFSYTQLDSLDEMFRARAQLESAARTLYTINGLSDR
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LIGQAAQYRLTQAADYTTGMFASLDSIRQGSEKLIASTPSAERRAAYERLRDQSTDLGKA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LPKLVELGAQIRENRAGVYANGDDLTKASGVLVAQLRATGQDAVIAQAVEVERTLLLFRI
HHHHHHHHHHHHHCCCCEEECCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MNWRFLATKDPKGRALSANAFGNAEAALAKLKALDLTAADQETAKLVGETLNRLNKSIVA
HCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ASQAIVESETFFEETLKPRVDGINATGVSVRSKLETALQDGVEQSNALMTRAKTVQLILL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLILATGAALAFLIARSLIRPISGMTAAMSRLAAGETAIEVPSRDAVDEMGRMAEAVEVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHH
RQNAVARIELEAERVAQQSARQRRADRVDGLVRGFEEKIAASIAIVTSAATELDSTARSM
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQVADNTNGQAVASSAAAEEATVNVQTVAAAAEEMVASLSEIERRVQQSNDVAGHASHEA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
RTTTDSMSHLSRAAEKIGEAVTMISGLASQTNLLALNATIEAARAGEAGRGFAVVATEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHH
ELAAQTARTTEAISDQVSAIQTASTQALGAIQQIGRTIVSVNDITASIAATVVQQTAATN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIARNASEAARGTQDVSMSVAQVQALSSETGSAAQQVMMASSELSTQSENVRREVEDFLA
HHHHCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIRAA
HHHCC
>Mature Secondary Structure
MKTGIRTRLYGGFSALVALSCGMGAFSYTQLDSLDEMFRARAQLESAARTLYTINGLSDR
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LIGQAAQYRLTQAADYTTGMFASLDSIRQGSEKLIASTPSAERRAAYERLRDQSTDLGKA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHCCCHHHHH
LPKLVELGAQIRENRAGVYANGDDLTKASGVLVAQLRATGQDAVIAQAVEVERTLLLFRI
HHHHHHHHHHHHHCCCCEEECCCCCHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
MNWRFLATKDPKGRALSANAFGNAEAALAKLKALDLTAADQETAKLVGETLNRLNKSIVA
HCCEEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
ASQAIVESETFFEETLKPRVDGINATGVSVRSKLETALQDGVEQSNALMTRAKTVQLILL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLILATGAALAFLIARSLIRPISGMTAAMSRLAAGETAIEVPSRDAVDEMGRMAEAVEVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHH
RQNAVARIELEAERVAQQSARQRRADRVDGLVRGFEEKIAASIAIVTSAATELDSTARSM
HHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQVADNTNGQAVASSAAAEEATVNVQTVAAAAEEMVASLSEIERRVQQSNDVAGHASHEA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCH
RTTTDSMSHLSRAAEKIGEAVTMISGLASQTNLLALNATIEAARAGEAGRGFAVVATEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHCCCCCCCHHHHHHHHH
ELAAQTARTTEAISDQVSAIQTASTQALGAIQQIGRTIVSVNDITASIAATVVQQTAATN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIARNASEAARGTQDVSMSVAQVQALSSETGSAAQQVMMASSELSTQSENVRREVEDFLA
HHHHCHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIRAA
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]