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The map label for this gene is moxX [H]

Identifier: 218532393

GI number: 218532393

Start: 4774647

End: 4775324

Strand: Reverse

Name: moxX [H]

Synonym: Mchl_4505

Alternate gene names: 218532393

Gene position: 4775324-4774647 (Counterclockwise)

Preceding gene: 218532394

Following gene: 218532389

Centisome position: 82.65

GC content: 70.8

Gene sequence:

>678_bases
GTGAGCGATGGACGCGCCTCCGCCCGGCCCCTGCCGGCGCGGCCGGAGACGATGCTCGTCATCGACGACCACCCGATCGT
GATGCAGGGGGTGCGCCGGCTGGCGGAAGCCGCGGGCGTGGCCAAAGTCTACGAGGCCGCCGACATCGTCTCGGGCTACC
GCCTGTTCCACCGGCACCGGCCGGCCCTGGTGGTGGCCGATCTGAGCTTTCGCGACGACGGCCTGTCCGGCCTGTCGCTG
ATCCGCCGCATCCGGGCGCTCGATCCGGCCGCGCGCATCCTCGTCTTCAGCATGCATGCCGACCCGGTGCTGGTCTCCCG
CGCCCTGGAAAGCGGCGCGCTCGGCTTCGCGCTCAAGGATGCCGGATCGGACGCCTTCCTGGAGGCGCTCGACGCCGTCC
ATGCCGGGCGGGGCTACCTGCCGCACGCGCTTGCTACCGACGTGGCGATGCTGAACCGCAGCGCCCGCCCCGCCCCGCTC
GCCACCTTGAGCGCGCGCGAATTGCAGATCCTGTCGCTGCTGAGCCAGGGCAAATCCTACGACGCCATCGCCAGCGCCAT
GGCGGTGAGCTACCGCACGATCATCAATGCCAGTTCCAGCATGCGCAAGAAGCTCGGCGTCGAGTCGCGCGCCGGGCTGG
TCCAGATCGCGGTCAACCGGCGCAACGCGCTGCTGTGA

Upstream 100 bases:

>100_bases
CGCTCACGCGCCTCGAAGCCCGCGAGCGGCCGGACATCGCCGCGCCGGAGATGCCGCCCGATCCGCCCCGGGAATCGGAA
AAACAGCCGGGAGGGCAGCC

Downstream 100 bases:

>100_bases
GCCGGTTCGAAGGCGTCCGCAGGCTTAACCCATCCTGATCTCGACCTCATCCTGAGGTGCCGGCGACAGCGGGCCTCGAA
GGATCCTCCAGGAAGCGCGC

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSDGRASARPLPARPETMLVIDDHPIVMQGVRRLAEAAGVAKVYEAADIVSGYRLFHRHRPALVVADLSFRDDGLSGLSL
IRRIRALDPAARILVFSMHADPVLVSRALESGALGFALKDAGSDAFLEALDAVHAGRGYLPHALATDVAMLNRSARPAPL
ATLSARELQILSLLSQGKSYDAIASAMAVSYRTIINASSSMRKKLGVESRAGLVQIAVNRRNALL

Sequences:

>Translated_225_residues
MSDGRASARPLPARPETMLVIDDHPIVMQGVRRLAEAAGVAKVYEAADIVSGYRLFHRHRPALVVADLSFRDDGLSGLSL
IRRIRALDPAARILVFSMHADPVLVSRALESGALGFALKDAGSDAFLEALDAVHAGRGYLPHALATDVAMLNRSARPAPL
ATLSARELQILSLLSQGKSYDAIASAMAVSYRTIINASSSMRKKLGVESRAGLVQIAVNRRNALL
>Mature_224_residues
SDGRASARPLPARPETMLVIDDHPIVMQGVRRLAEAAGVAKVYEAADIVSGYRLFHRHRPALVVADLSFRDDGLSGLSLI
RRIRALDPAARILVFSMHADPVLVSRALESGALGFALKDAGSDAFLEALDAVHAGRGYLPHALATDVAMLNRSARPAPLA
TLSARELQILSLLSQGKSYDAIASAMAVSYRTIINASSSMRKKLGVESRAGLVQIAVNRRNALL

Specific function: Member of the two-component regulatory system moxY/moxX probably involved in the regulation of the methanol dehydrogenase expression [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=205, Percent_Identity=25.8536585365854, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788521, Length=215, Percent_Identity=29.7674418604651, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786747, Length=208, Percent_Identity=24.5192307692308, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788712, Length=206, Percent_Identity=24.7572815533981, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788546, Length=201, Percent_Identity=27.8606965174129, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787473, Length=185, Percent_Identity=32.972972972973, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=29.4416243654822, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24057; Mature: 23926

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGRASARPLPARPETMLVIDDHPIVMQGVRRLAEAAGVAKVYEAADIVSGYRLFHRHR
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALVVADLSFRDDGLSGLSLIRRIRALDPAARILVFSMHADPVLVSRALESGALGFALKD
CEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHEEEEECCCCHHHHHHHHHCCCCEEEEEC
AGSDAFLEALDAVHAGRGYLPHALATDVAMLNRSARPAPLATLSARELQILSLLSQGKSY
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
DAIASAMAVSYRTIINASSSMRKKLGVESRAGLVQIAVNRRNALL
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SDGRASARPLPARPETMLVIDDHPIVMQGVRRLAEAAGVAKVYEAADIVSGYRLFHRHR
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PALVVADLSFRDDGLSGLSLIRRIRALDPAARILVFSMHADPVLVSRALESGALGFALKD
CEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHEEEEECCCCHHHHHHHHHCCCCEEEEEC
AGSDAFLEALDAVHAGRGYLPHALATDVAMLNRSARPAPLATLSARELQILSLLSQGKSY
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
DAIASAMAVSYRTIINASSSMRKKLGVESRAGLVQIAVNRRNALL
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8392137 [H]