Click here to switch to the map view.

The map label for this gene is aacC1 [H]

Identifier: 218532199

GI number: 218532199

Start: 4552493

End: 4553041

Strand: Reverse

Name: aacC1 [H]

Synonym: Mchl_4311

Alternate gene names: 218532199

Gene position: 4553041-4552493 (Counterclockwise)

Preceding gene: 218532200

Following gene: 218532198

Centisome position: 78.8

GC content: 71.4

Gene sequence:

>549_bases
ATGACGTCGAAGACGGATGGGGCCGAGCCGGGCTTCACGGTCCGGCGCCTCGGGCCCAACGACATCCCGTCGATGCGCGC
CCTCAACGCCCTGTTCGGACGCGCCTTCGCCGAGCCCGACACCTACGGCGCCACCCCGCCGGACGACGCCTACCTTGCGG
ACCTGCTGGCCAAGGCGCATGTCGCGGTGCTGGTGGCGGAACGTGACGGCACCGTTCTGGGTGGCCTCGTCGCCTACGAG
CTCGACAAGTTCGAGCGGGCACGGCGCGAGATCTACCTCTACGATCTCGCCGTCGAGGCCGAGCACCGCCGCCGCGGCAT
CGCCACGGCGCTGATCCGGCAGCTGCAGGCTCATGCCGCGGGCCGAGGCGCCTGGGTCATCTTCGTCCAGGGCGATCCCG
GCGACGGCCCGGCGCTCGCGCTCTACGACCGGCTCGGCACCCGCGAGGAAGTCCTGCATTTCGACCTGCCCGTCGGGGCC
CTGCCCTTGCCATCGGAAGCGAATCCCTCTAAAGGCCCGGCCTTCGCGTTCGCTCCGGCCGGGGGCTGA

Upstream 100 bases:

>100_bases
CTCGGGGCGGCCCGACCCGATCCAGCGCACGCTCAAGCGCGGCGCCGACATCTTGGGGATTCAGCAGGCCATCGCCGGCT
CGTTGAAATAGACCTCCGCC

Downstream 100 bases:

>100_bases
ACGGACGGTGCCGCAAGAGACGACCTCTCTCGGCACAGGGTTTTTCACAGAACCCGTCGTCCGGTGTCTCCGCCTTCGAT
CAACCGCTCGGGCCATCATC

Product: Gentamicin 3'-N-acetyltransferase

Products: NA

Alternate protein names: AAC(3)-I; Aminoglycoside N(3')-acetyltransferase I; Gentamicin acetyltransferase I [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MTSKTDGAEPGFTVRRLGPNDIPSMRALNALFGRAFAEPDTYGATPPDDAYLADLLAKAHVAVLVAERDGTVLGGLVAYE
LDKFERARREIYLYDLAVEAEHRRRGIATALIRQLQAHAAGRGAWVIFVQGDPGDGPALALYDRLGTREEVLHFDLPVGA
LPLPSEANPSKGPAFAFAPAGG

Sequences:

>Translated_182_residues
MTSKTDGAEPGFTVRRLGPNDIPSMRALNALFGRAFAEPDTYGATPPDDAYLADLLAKAHVAVLVAERDGTVLGGLVAYE
LDKFERARREIYLYDLAVEAEHRRRGIATALIRQLQAHAAGRGAWVIFVQGDPGDGPALALYDRLGTREEVLHFDLPVGA
LPLPSEANPSKGPAFAFAPAGG
>Mature_181_residues
TSKTDGAEPGFTVRRLGPNDIPSMRALNALFGRAFAEPDTYGATPPDDAYLADLLAKAHVAVLVAERDGTVLGGLVAYEL
DKFERARREIYLYDLAVEAEHRRRGIATALIRQLQAHAAGRGAWVIFVQGDPGDGPALALYDRLGTREEVLHFDLPVGAL
PLPSEANPSKGPAFAFAPAGG

Specific function: Responsible for gentamicin resistance and has a limited substrate range [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.60 [H]

Molecular weight: Translated: 19436; Mature: 19305

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKTDGAEPGFTVRRLGPNDIPSMRALNALFGRAFAEPDTYGATPPDDAYLADLLAKAH
CCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHE
VAVLVAERDGTVLGGLVAYELDKFERARREIYLYDLAVEAEHRRRGIATALIRQLQAHAA
EEEEEECCCCCEEHHHHHHHHHHHHHHHHEEEEEEEEEECHHHHHHHHHHHHHHHHHHCC
GRGAWVIFVQGDPGDGPALALYDRLGTREEVLHFDLPVGALPLPSEANPSKGPAFAFAPA
CCCEEEEEEECCCCCCCEEEEHHHCCCHHHEEEEECCCCCCCCCCCCCCCCCCEEEEECC
GG
CC
>Mature Secondary Structure 
TSKTDGAEPGFTVRRLGPNDIPSMRALNALFGRAFAEPDTYGATPPDDAYLADLLAKAH
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHE
VAVLVAERDGTVLGGLVAYELDKFERARREIYLYDLAVEAEHRRRGIATALIRQLQAHAA
EEEEEECCCCCEEHHHHHHHHHHHHHHHHEEEEEEEEEECHHHHHHHHHHHHHHHHHHCC
GRGAWVIFVQGDPGDGPALALYDRLGTREEVLHFDLPVGALPLPSEANPSKGPAFAFAPA
CCCEEEEEEECCCCCCCEEEEHHHCCCHHHEEEEECCCCCCCCCCCCCCCCCCEEEEECC
GG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2549372 [H]