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The map label for this gene is yciR [C]

Identifier: 218532082

GI number: 218532082

Start: 4401739

End: 4403841

Strand: Reverse

Name: yciR [C]

Synonym: Mchl_4176

Alternate gene names: 218532082

Gene position: 4403841-4401739 (Counterclockwise)

Preceding gene: 218532084

Following gene: 218532078

Centisome position: 76.22

GC content: 70.38

Gene sequence:

>2103_bases
ATGCCCCTGAACGACCTCGAAGAACTCGCGCGAATCGCCTTCGACTGGCTCTGGGCCACCGATCCCGAGGATCGATTCAG
CTACGTCTCCCCAGGCGCCGAGCGTGTGCTGGGCCGCTCTCCGGCGGACCTGATCGGGCTCACGCGGTCGGCCCTGGTCT
GCGAGGGGGAGGGTGAGAGCCTTGCCGTCTACCGCGAGACGATCACCGCCCGCCGCCCGTTCCGCGACCTGACCTACGTC
TACCGCCATCCCGACGGCACGCCGCGCTGGTTCGAGATCAGCGGCCGCCCGCATTTCTCGCCCGAGGGCGATTTCCTGGG
CTATCACGGCGTCGGCAGCGACGTCACCGAGCAGCACCGGACCCGGTGCGCCCTGGTCGAGGCGCACGCCGAACTCAGCG
AGCAGAACCGGCGCTTCGACGCGGCCCTGGAGAACATGACGCACGGCCTGTGCATGTTCGATGCGGAGCAGCGGCTCCTG
GTGTGGAACCGGCGCTACCTGGGGATCTTCGGCCTGCCCGACGACGCGGTCCATGTCGGCATGGGCCAGCGCGCCATCAT
CGAGATGCTGGTGGCGCGCGGGTGCTACAAGCGCGGCGCCACAGTCGATGCGATCAGCGAGGGCACCCGCACCTCGCTCA
GCGGAGACGGGTCGAAATCGGTTTTGCGCGAACTCGCCGACGGGCGGGTCATCGCCGTGACCCACCGGCCCATGGCCGAT
GGCGGCGGCTGGGTGGCGACCTTCGAGGACATCACGGAGCGGCGGCGCAACGAGGCGCGCATCATCCACATGGCCCGCCA
CGACGGGCTCACCGACCTGCCGAACCGCACCCACCTGCGCGAGGTCGGCGCCGAATGGCTCGCGGCGTTGCGCACCGCCG
CGGAGGCGCCGCTCGCGGTGCTCTGCCTCGACCTCGACCGGTTCAAGCCGGTCAACGACAGCTTCGGCCACGCGGTGGGC
GATGCCCTGCTGCGGGCGGTGGCCGATCGGCTGCGCGGGCACGTGCGCAGCCACGACGTGGTGGCCCGGCTCGGCGGCGA
CGAATTCGCGGTGCTGTCCCGCGTCGAGGATGCGGCCGCGGCCGCGGCCCTGGCCGAGCGCCTGATCGAGACCGTGGGCG
CGCCCTACACCCTCGACGGGATCACCGTCGAGATCGGGATGAGCGCCGGCATCGCCCTGGCCGAGGGCGACGTCCCGCAC
GACATCGAGCGCCTCCTCAAGGAGGCCGACCTCGCCCTCTACGAGGCGAAGACCGAGGGGCGCGGCACCGTCCGCCTGTT
CGAGCCGCAGATGGACGAGACCCTGCGCGAGCGGCTCGGCCTCGAACGCGAGCTGCGCGAGGCGCTCACGCTGGACCGCT
TCGAACTGCATTATCAGCCGCTCGTGAACCTGTCCGACAACCGCATCACCGGCATGGAGGCGCTGATCCGCTGGCACCAT
CCCGAGCGCGGGCTCGTGAGCCCGGCGGTGTTCATCCCGCTCGCCGAGGAGACCGGTCTGATCGTGCCGATCGGCGAATG
GGTGCTGCGCCAGGCCTGCCGGGACGCGGTGGACTGGCCGGGCGAGATCAGTGTGGCCGTCAACGTCTCGCCGCTGCAGC
TGCGCCACCGCGGCTTCATCCAGAGCGTGCTCGGCGCGCTCGCGGCCAGCGGCCTCAAGGCGAGCCGGCTCGAACTGGAA
ATCACCGAGAACGTGCTGCTCGATGACACCGAGGCGAACCTCGAAACGCTCCACACCCTGCGCAAGCTCGGCGTGCGCAT
CTCCATGGACGATTTCGGAACCGGCTATTCCTCGATCAGCTACCTGCGCCGCTTCCCCTTCGACAAGATCAAGATCGACC
GTTCCTTCGTGCGTGACTGCGCCGCCCAGTCGGAGGCCGGTGCGATCATCCGCGCCATCGTGAGCCTGGGGGCGAGCCTC
GGCATCACCACCCTGGTCGAAGGCGTCGAGACCGAGCCGCAGCTCGCCACGATCCGGGCGGAGGGCGCGCAGGAGGTGCA
GGGTTACCTGTTCAGTCCGCCCCGCCCGGTTCACGAGATCGCCGTCCTGCTCGAAGCCGGGACCACGGCCGAGGGCCGGC
CCGGGCGGACGCTGGCAGCCTGA

Upstream 100 bases:

>100_bases
CAGCACGGAACGTGTAAAATTTGGGCAGAATGTCCAAGTCGCGGTCATGAGGAAATATTCACTTTTAGGCGTAAAAGTCC
GGCTCGTCCGCGGTGATCTC

Downstream 100 bases:

>100_bases
CGGATCTTTTCGCGAGCTTTCGAGCGCCGGGGACAGGCTCCAGGCACCGCTACGCGTCGAAGCCCCGCCCTGCCCCGCCA
GGGTTCGAAATCCGATCGGC

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MPLNDLEELARIAFDWLWATDPEDRFSYVSPGAERVLGRSPADLIGLTRSALVCEGEGESLAVYRETITARRPFRDLTYV
YRHPDGTPRWFEISGRPHFSPEGDFLGYHGVGSDVTEQHRTRCALVEAHAELSEQNRRFDAALENMTHGLCMFDAEQRLL
VWNRRYLGIFGLPDDAVHVGMGQRAIIEMLVARGCYKRGATVDAISEGTRTSLSGDGSKSVLRELADGRVIAVTHRPMAD
GGGWVATFEDITERRRNEARIIHMARHDGLTDLPNRTHLREVGAEWLAALRTAAEAPLAVLCLDLDRFKPVNDSFGHAVG
DALLRAVADRLRGHVRSHDVVARLGGDEFAVLSRVEDAAAAAALAERLIETVGAPYTLDGITVEIGMSAGIALAEGDVPH
DIERLLKEADLALYEAKTEGRGTVRLFEPQMDETLRERLGLERELREALTLDRFELHYQPLVNLSDNRITGMEALIRWHH
PERGLVSPAVFIPLAEETGLIVPIGEWVLRQACRDAVDWPGEISVAVNVSPLQLRHRGFIQSVLGALAASGLKASRLELE
ITENVLLDDTEANLETLHTLRKLGVRISMDDFGTGYSSISYLRRFPFDKIKIDRSFVRDCAAQSEAGAIIRAIVSLGASL
GITTLVEGVETEPQLATIRAEGAQEVQGYLFSPPRPVHEIAVLLEAGTTAEGRPGRTLAA

Sequences:

>Translated_700_residues
MPLNDLEELARIAFDWLWATDPEDRFSYVSPGAERVLGRSPADLIGLTRSALVCEGEGESLAVYRETITARRPFRDLTYV
YRHPDGTPRWFEISGRPHFSPEGDFLGYHGVGSDVTEQHRTRCALVEAHAELSEQNRRFDAALENMTHGLCMFDAEQRLL
VWNRRYLGIFGLPDDAVHVGMGQRAIIEMLVARGCYKRGATVDAISEGTRTSLSGDGSKSVLRELADGRVIAVTHRPMAD
GGGWVATFEDITERRRNEARIIHMARHDGLTDLPNRTHLREVGAEWLAALRTAAEAPLAVLCLDLDRFKPVNDSFGHAVG
DALLRAVADRLRGHVRSHDVVARLGGDEFAVLSRVEDAAAAAALAERLIETVGAPYTLDGITVEIGMSAGIALAEGDVPH
DIERLLKEADLALYEAKTEGRGTVRLFEPQMDETLRERLGLERELREALTLDRFELHYQPLVNLSDNRITGMEALIRWHH
PERGLVSPAVFIPLAEETGLIVPIGEWVLRQACRDAVDWPGEISVAVNVSPLQLRHRGFIQSVLGALAASGLKASRLELE
ITENVLLDDTEANLETLHTLRKLGVRISMDDFGTGYSSISYLRRFPFDKIKIDRSFVRDCAAQSEAGAIIRAIVSLGASL
GITTLVEGVETEPQLATIRAEGAQEVQGYLFSPPRPVHEIAVLLEAGTTAEGRPGRTLAA
>Mature_699_residues
PLNDLEELARIAFDWLWATDPEDRFSYVSPGAERVLGRSPADLIGLTRSALVCEGEGESLAVYRETITARRPFRDLTYVY
RHPDGTPRWFEISGRPHFSPEGDFLGYHGVGSDVTEQHRTRCALVEAHAELSEQNRRFDAALENMTHGLCMFDAEQRLLV
WNRRYLGIFGLPDDAVHVGMGQRAIIEMLVARGCYKRGATVDAISEGTRTSLSGDGSKSVLRELADGRVIAVTHRPMADG
GGWVATFEDITERRRNEARIIHMARHDGLTDLPNRTHLREVGAEWLAALRTAAEAPLAVLCLDLDRFKPVNDSFGHAVGD
ALLRAVADRLRGHVRSHDVVARLGGDEFAVLSRVEDAAAAAALAERLIETVGAPYTLDGITVEIGMSAGIALAEGDVPHD
IERLLKEADLALYEAKTEGRGTVRLFEPQMDETLRERLGLERELREALTLDRFELHYQPLVNLSDNRITGMEALIRWHHP
ERGLVSPAVFIPLAEETGLIVPIGEWVLRQACRDAVDWPGEISVAVNVSPLQLRHRGFIQSVLGALAASGLKASRLELEI
TENVLLDDTEANLETLHTLRKLGVRISMDDFGTGYSSISYLRRFPFDKIKIDRSFVRDCAAQSEAGAIIRAIVSLGASLG
ITTLVEGVETEPQLATIRAEGAQEVQGYLFSPPRPVHEIAVLLEAGTTAEGRPGRTLAA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=430, Percent_Identity=38.1395348837209, Blast_Score=297, Evalue=2e-81,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=34.2592592592593, Blast_Score=253, Evalue=4e-68,
Organism=Escherichia coli, GI226510982, Length=415, Percent_Identity=28.9156626506024, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI1788502, Length=265, Percent_Identity=33.9622641509434, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=34.8837209302326, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1787055, Length=248, Percent_Identity=35.4838709677419, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=34.7639484978541, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI87081845, Length=248, Percent_Identity=35.0806451612903, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1790496, Length=244, Percent_Identity=31.1475409836066, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1788381, Length=633, Percent_Identity=24.9605055292259, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=32.2033898305085, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788849, Length=444, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87082096, Length=198, Percent_Identity=30.8080808080808, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=36.6863905325444, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081881, Length=217, Percent_Identity=35.4838709677419, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=175, Percent_Identity=37.7142857142857, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87082007, Length=162, Percent_Identity=38.2716049382716, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=34.8066298342541, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI87081977, Length=182, Percent_Identity=31.8681318681319, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=32.9268292682927, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=31.0975609756098, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=33.1288343558282, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1788956, Length=207, Percent_Identity=31.8840579710145, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787410, Length=156, Percent_Identity=25.6410256410256, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=153, Percent_Identity=32.6797385620915, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 77114; Mature: 76983

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNDLEELARIAFDWLWATDPEDRFSYVSPGAERVLGRSPADLIGLTRSALVCEGEGES
CCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHCCCCHHHHHHCCCEEEECCCCCE
LAVYRETITARRPFRDLTYVYRHPDGTPRWFEISGRPHFSPEGDFLGYHGVGSDVTEQHR
EEHHHHHHHHCCCHHHHHEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHH
TRCALVEAHAELSEQNRRFDAALENMTHGLCMFDAEQRLLVWNRRYLGIFGLPDDAVHVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCEEEEECCCCCCEEEC
MGQRAIIEMLVARGCYKRGATVDAISEGTRTSLSGDGSKSVLRELADGRVIAVTHRPMAD
CCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCC
GGGWVATFEDITERRRNEARIIHMARHDGLTDLPNRTHLREVGAEWLAALRTAAEAPLAV
CCCEEEEHHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
LCLDLDRFKPVNDSFGHAVGDALLRAVADRLRGHVRSHDVVARLGGDEFAVLSRVEDAAA
EEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHHH
AAALAERLIETVGAPYTLDGITVEIGMSAGIALAEGDVPHDIERLLKEADLALYEAKTEG
HHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHEEEECCCC
RGTVRLFEPQMDETLRERLGLERELREALTLDRFELHYQPLVNLSDNRITGMEALIRWHH
CCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCC
PERGLVSPAVFIPLAEETGLIVPIGEWVLRQACRDAVDWPGEISVAVNVSPLQLRHRGFI
CCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHH
QSVLGALAASGLKASRLELEITENVLLDDTEANLETLHTLRKLGVRISMDDFGTGYSSIS
HHHHHHHHHCCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHCCEEEEHHCCCCHHHHH
YLRRFPFDKIKIDRSFVRDCAAQSEAGAIIRAIVSLGASLGITTLVEGVETEPQLATIRA
HHHHCCCHHEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEC
EGAQEVQGYLFSPPRPVHEIAVLLEAGTTAEGRPGRTLAA
CCHHHHCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLNDLEELARIAFDWLWATDPEDRFSYVSPGAERVLGRSPADLIGLTRSALVCEGEGES
CCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHCCCCHHHHHHCCCEEEECCCCCE
LAVYRETITARRPFRDLTYVYRHPDGTPRWFEISGRPHFSPEGDFLGYHGVGSDVTEQHR
EEHHHHHHHHCCCHHHHHEEEECCCCCCCEEEECCCCCCCCCCCEEEECCCCCCHHHHHH
TRCALVEAHAELSEQNRRFDAALENMTHGLCMFDAEQRLLVWNRRYLGIFGLPDDAVHVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCEEEEECCCCCCEEEC
MGQRAIIEMLVARGCYKRGATVDAISEGTRTSLSGDGSKSVLRELADGRVIAVTHRPMAD
CCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCC
GGGWVATFEDITERRRNEARIIHMARHDGLTDLPNRTHLREVGAEWLAALRTAAEAPLAV
CCCEEEEHHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEE
LCLDLDRFKPVNDSFGHAVGDALLRAVADRLRGHVRSHDVVARLGGDEFAVLSRVEDAAA
EEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCHHHHHHHHHHHHH
AAALAERLIETVGAPYTLDGITVEIGMSAGIALAEGDVPHDIERLLKEADLALYEAKTEG
HHHHHHHHHHHCCCCEEECCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHEEEECCCC
RGTVRLFEPQMDETLRERLGLERELREALTLDRFELHYQPLVNLSDNRITGMEALIRWHH
CCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCC
PERGLVSPAVFIPLAEETGLIVPIGEWVLRQACRDAVDWPGEISVAVNVSPLQLRHRGFI
CCCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHH
QSVLGALAASGLKASRLELEITENVLLDDTEANLETLHTLRKLGVRISMDDFGTGYSSIS
HHHHHHHHHCCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHHCCEEEEHHCCCCHHHHH
YLRRFPFDKIKIDRSFVRDCAAQSEAGAIIRAIVSLGASLGITTLVEGVETEPQLATIRA
HHHHCCCHHEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEC
EGAQEVQGYLFSPPRPVHEIAVLLEAGTTAEGRPGRTLAA
CCHHHHCCEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]