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The map label for this gene is norM [H]

Identifier: 218532027

GI number: 218532027

Start: 4340599

End: 4342005

Strand: Reverse

Name: norM [H]

Synonym: Mchl_4118

Alternate gene names: 218532027

Gene position: 4342005-4340599 (Counterclockwise)

Preceding gene: 218532028

Following gene: 218532026

Centisome position: 75.15

GC content: 70.01

Gene sequence:

>1407_bases
ATGGACGTCCGCACCCGCCGCCTCCTCACGGCCCCTATCGTGCCGACCCTGGCCCGGATGGCCGTGCCCAACATCCTGGT
GATGGCGGTCCAGACCTCCGTCGGCCTGATCGAAACGTATTTCGTGTCGATGCTCGGGACGGACGCATTGGCCGGGATGG
CCCTCGTCTTTCCGGTGGTGATGCTGGTCCAGATGCTCTCCGCCGGCGGGATGGGGGGCGCCATCCAATCGGCGGTCTCC
CGCACGCTGGGTGCGGACCGGCAGGCGGAGGCCGGAATTCTGGCGTGGCACGCGATGGTGCTCGGCCTGGGGCTCGGCAT
TGCGACGAGCCTCGTCGCCCTTCCGTTCGGGCCGACCCTCTACGCGGCGATGGGCGGGACCGGAGGCTCGCTCCGAGCGG
CGACCACCTACGCGTCCATCGTGTTCGGTGGGGCGGTCCTGATCTGGCTGTTCAACGCGCTGTCGGCCGTGATCCGCGGC
ACCGGCAACATGGTGCTTCCGGCCATCGTCACCTGCGTCGGGGCCGTCGTGCTGATCCCGCTCTCGCCCGCGCTCATCTT
CGGCTGGGGGCCGTTCCCTGAGTTCGGCGTCGCGGGCGGTGGCGTGGCGTTTGCGGCCTACTACGCCGCGGGGTCCGCGG
TCTTCGCCGCCTACATCTGGTCCGGCCGCAGCGTCCTCCGCCCGAGCCGGCGCTTGCCCGCTCTCTCTTGGGGGCCGTCA
CGGGAGATCCTGCGCATCGGGGTTCTTTCGGGCATCGCGAGCGTGACCTCGAACGTCACAGTCATCGTGGCGACCGGCTT
CGCCGGGGCGGCGGGGCCGGCGGCCGTGGCCGGCTACGGGACAGGCTCCCGGCTCGAATACCTCTTGGTCCCCCTCGTGT
TCGGTCTCGGCTCTCCCATCGCAGCCATCGTCGGTACGGCCCTGGGAGCGGGCGACCACGCACGAGCCCGCCAGGCGGCA
CTGACAGGTGCCCTCATCGCCGGTGTCCTGACGGAGTTCATCGGGCTCGCGGCCGCCCTGCACCCGGCTGCGTGGCTCGG
CTTGTTCGGAGACGATCCGGCGATGCTCGCAACGGGCTCGCTCTACCTGCGAATCGTCGGCCCGTTCTACGGATTTTTCG
GCTTCGGGCTGGCCCTGTACTTCGCCGCCCAGGGTGCAGGACGTGTCGGCTGGCCACTCGCCGCCAGCCTCCTTCGGATG
GGGGTTGCATTGGGCGGCGCTTGGCTCGCTTTGGCGCTCGGGCTCGGCCTCGCCGGAACATTCATCGCCATGTCAGCCGG
GTTCGTCACCATGGGGCTCGTCAACGCGGCGGCCTTCGCGACGGGCAAGATGTTCCCGAGCGAAGCCCTCGGCCCACCCT
CCGTAACTTCCGGAACCCTAGCTCCAGCCGCGGGCGTGAGACGCTGA

Upstream 100 bases:

>100_bases
GTCCAAGCAAGCCGAGGCCGGCACGGATGGCCCGAGCGTCCACCTGCGTTCCGTGGACGGCCAGTAGCGCGTCGTCGGAC
TATCTCGGACAGGAGCCCTC

Downstream 100 bases:

>100_bases
CTTCCGCACCATAGGGGACAGGAAGGATCTCCATCACGCCGTGTAAACGGCAACTCGGCGACCGGGCGCTCCGGATACTG
CTCGCGACGGTCTTCGTCCG

Product: MATE efflux family protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MDVRTRRLLTAPIVPTLARMAVPNILVMAVQTSVGLIETYFVSMLGTDALAGMALVFPVVMLVQMLSAGGMGGAIQSAVS
RTLGADRQAEAGILAWHAMVLGLGLGIATSLVALPFGPTLYAAMGGTGGSLRAATTYASIVFGGAVLIWLFNALSAVIRG
TGNMVLPAIVTCVGAVVLIPLSPALIFGWGPFPEFGVAGGGVAFAAYYAAGSAVFAAYIWSGRSVLRPSRRLPALSWGPS
REILRIGVLSGIASVTSNVTVIVATGFAGAAGPAAVAGYGTGSRLEYLLVPLVFGLGSPIAAIVGTALGAGDHARARQAA
LTGALIAGVLTEFIGLAAALHPAAWLGLFGDDPAMLATGSLYLRIVGPFYGFFGFGLALYFAAQGAGRVGWPLAASLLRM
GVALGGAWLALALGLGLAGTFIAMSAGFVTMGLVNAAAFATGKMFPSEALGPPSVTSGTLAPAAGVRR

Sequences:

>Translated_468_residues
MDVRTRRLLTAPIVPTLARMAVPNILVMAVQTSVGLIETYFVSMLGTDALAGMALVFPVVMLVQMLSAGGMGGAIQSAVS
RTLGADRQAEAGILAWHAMVLGLGLGIATSLVALPFGPTLYAAMGGTGGSLRAATTYASIVFGGAVLIWLFNALSAVIRG
TGNMVLPAIVTCVGAVVLIPLSPALIFGWGPFPEFGVAGGGVAFAAYYAAGSAVFAAYIWSGRSVLRPSRRLPALSWGPS
REILRIGVLSGIASVTSNVTVIVATGFAGAAGPAAVAGYGTGSRLEYLLVPLVFGLGSPIAAIVGTALGAGDHARARQAA
LTGALIAGVLTEFIGLAAALHPAAWLGLFGDDPAMLATGSLYLRIVGPFYGFFGFGLALYFAAQGAGRVGWPLAASLLRM
GVALGGAWLALALGLGLAGTFIAMSAGFVTMGLVNAAAFATGKMFPSEALGPPSVTSGTLAPAAGVRR
>Mature_468_residues
MDVRTRRLLTAPIVPTLARMAVPNILVMAVQTSVGLIETYFVSMLGTDALAGMALVFPVVMLVQMLSAGGMGGAIQSAVS
RTLGADRQAEAGILAWHAMVLGLGLGIATSLVALPFGPTLYAAMGGTGGSLRAATTYASIVFGGAVLIWLFNALSAVIRG
TGNMVLPAIVTCVGAVVLIPLSPALIFGWGPFPEFGVAGGGVAFAAYYAAGSAVFAAYIWSGRSVLRPSRRLPALSWGPS
REILRIGVLSGIASVTSNVTVIVATGFAGAAGPAAVAGYGTGSRLEYLLVPLVFGLGSPIAAIVGTALGAGDHARARQAA
LTGALIAGVLTEFIGLAAALHPAAWLGLFGDDPAMLATGSLYLRIVGPFYGFFGFGLALYFAAQGAGRVGWPLAASLLRM
GVALGGAWLALALGLGLAGTFIAMSAGFVTMGLVNAAAFATGKMFPSEALGPPSVTSGTLAPAAGVRR

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 46984; Mature: 46984

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRTRRLLTAPIVPTLARMAVPNILVMAVQTSVGLIETYFVSMLGTDALAGMALVFPVV
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVQMLSAGGMGGAIQSAVSRTLGADRQAEAGILAWHAMVLGLGLGIATSLVALPFGPTL
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YAAMGGTGGSLRAATTYASIVFGGAVLIWLFNALSAVIRGTGNMVLPAIVTCVGAVVLIP
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
LSPALIFGWGPFPEFGVAGGGVAFAAYYAAGSAVFAAYIWSGRSVLRPSRRLPALSWGPS
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHCCCCCCCCCC
REILRIGVLSGIASVTSNVTVIVATGFAGAAGPAAVAGYGTGSRLEYLLVPLVFGLGSPI
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCHH
AAIVGTALGAGDHARARQAALTGALIAGVLTEFIGLAAALHPAAWLGLFGDDPAMLATGS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC
LYLRIVGPFYGFFGFGLALYFAAQGAGRVGWPLAASLLRMGVALGGAWLALALGLGLAGT
HHEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIAMSAGFVTMGLVNAAAFATGKMFPSEALGPPSVTSGTLAPAAGVRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDVRTRRLLTAPIVPTLARMAVPNILVMAVQTSVGLIETYFVSMLGTDALAGMALVFPVV
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVQMLSAGGMGGAIQSAVSRTLGADRQAEAGILAWHAMVLGLGLGIATSLVALPFGPTL
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YAAMGGTGGSLRAATTYASIVFGGAVLIWLFNALSAVIRGTGNMVLPAIVTCVGAVVLIP
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
LSPALIFGWGPFPEFGVAGGGVAFAAYYAAGSAVFAAYIWSGRSVLRPSRRLPALSWGPS
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHCCCCCCCCCC
REILRIGVLSGIASVTSNVTVIVATGFAGAAGPAAVAGYGTGSRLEYLLVPLVFGLGSPI
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEECCCCCCHHHHHHHHHHHCCCCHH
AAIVGTALGAGDHARARQAALTGALIAGVLTEFIGLAAALHPAAWLGLFGDDPAMLATGS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC
LYLRIVGPFYGFFGFGLALYFAAQGAGRVGWPLAASLLRMGVALGGAWLALALGLGLAGT
HHEEHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIAMSAGFVTMGLVNAAAFATGKMFPSEALGPPSVTSGTLAPAAGVRR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]