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The map label for this gene is hcr [H]

Identifier: 218531954

GI number: 218531954

Start: 4257330

End: 4258457

Strand: Reverse

Name: hcr [H]

Synonym: Mchl_4042

Alternate gene names: 218531954

Gene position: 4258457-4257330 (Counterclockwise)

Preceding gene: 218531955

Following gene: 218531953

Centisome position: 73.7

GC content: 70.12

Gene sequence:

>1128_bases
ATGGCCCCGGCCTCCTCCGAACCGGCCGCCCGGCGGCTGGCGGCCTCCGCGCCCTGGGATGCGGAGGCCGACGACGCCTT
GGTCTGCCTCGCGGTGCGCGACGAGACGCACGACGTGAAGACCTTCGTGCTGGCGCCCAAGGAGCCCCGGCTCTTCGCCT
ACGCCCCGGGCCAGTTCCTGACCTTCTCGTTCGAGATCGGCGGCGAGACCATCCACCGCTGCTACACCATCTCCTCGGCG
CCGACCCGGCCGCACGCGGTCTCGTTCACGGTCAAGCGCGTGCCCGGCGGCCCGGTCTCGAACTGGCTGCACGACACCCT
CAAGCCCGGCGACACCGTTCGTGCGCTCGGGCCGATGGGCGAGTTCTCCTGCTTCTCCCACCCGGCCCCAAAATATCTGC
TCCTGTCCGGCGGCAGCGGCGTGACGCCGATGATGTCGATGGCGCGCAGCTTCCACGATCTGGGCGAAGCCCGCGACGTC
GCCTTCGTCCACTCCGCCCGCTCGCCCGCCGACATCGTGTTCCGGGGTGAACTGGAGACGATGGCCCGGCTCGATCCCGC
CTTCCACTTCCACGCGGTCTGCGAGACCGATTCCCCCAACGAGACTTGGGCGGGTCCGAAGGGCCGGCTCTCCCTCGACA
TCCTTCGCGAGGCGGTGCCGGACTTCCTCGAGCGCGAAGTCTTCGTCTGCGGCCCCAAACCCTACATGGACGCGGTGCGG
GCCATGCTGAGCCAAGCCGGCTTCGACATGGCCCGGCATCATCAGGAGAGCTTCGACTTCGGCGAACTGCCGGAGGCCGA
GCAGGAGGCTGCGGCGGAAGCCGAGAAGGCCCTCGACGCCGAGGCCGCGCCCGCGGGTGGCGTGCGCATCTTCCGGGTGG
AGTTCGCCAAGACCCGCCGGGTGCTCGAATGCCCGGAGAACGAGACGGTGCTCGACGCCGCCCGCAAGGCCGGCATCCGC
CTGCCCTCCTCCTGCGCCAAGGGCCTGTGCGGCACCTGCAAGTCGAAGCTCACCGCCGGCACCGTCGCCATGACCCATGC
CGGCGGCATCCGTCAGCGCGAGATCGATGCCGGCATGGCGCTGCTCTGCTGCTCGAAGCCGACCAGCGACCTCGTCATCG
AACGCTGA

Upstream 100 bases:

>100_bases
CTACGAGCCCGGCCCCTACTCGCCGCATACCGAGATGCTCGTGGAGAAGTTCTGCAACTGGTATGTCGGCCGCATGGCCG
CGCATCTGGGGCGCTGAGCC

Downstream 100 bases:

>100_bases
ACGGGCGGGCTCGGCCCCGCCCGCGACCCCACGCTTTCCCCATCGCCTTCGGGAGTCGTCCCGTGATCGCCAATGCCGAC
GCGCTCTTGAAGCCCCTCAC

Product: oxidoreductase FAD-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAPASSEPAARRLAASAPWDAEADDALVCLAVRDETHDVKTFVLAPKEPRLFAYAPGQFLTFSFEIGGETIHRCYTISSA
PTRPHAVSFTVKRVPGGPVSNWLHDTLKPGDTVRALGPMGEFSCFSHPAPKYLLLSGGSGVTPMMSMARSFHDLGEARDV
AFVHSARSPADIVFRGELETMARLDPAFHFHAVCETDSPNETWAGPKGRLSLDILREAVPDFLEREVFVCGPKPYMDAVR
AMLSQAGFDMARHHQESFDFGELPEAEQEAAAEAEKALDAEAAPAGGVRIFRVEFAKTRRVLECPENETVLDAARKAGIR
LPSSCAKGLCGTCKSKLTAGTVAMTHAGGIRQREIDAGMALLCCSKPTSDLVIER

Sequences:

>Translated_375_residues
MAPASSEPAARRLAASAPWDAEADDALVCLAVRDETHDVKTFVLAPKEPRLFAYAPGQFLTFSFEIGGETIHRCYTISSA
PTRPHAVSFTVKRVPGGPVSNWLHDTLKPGDTVRALGPMGEFSCFSHPAPKYLLLSGGSGVTPMMSMARSFHDLGEARDV
AFVHSARSPADIVFRGELETMARLDPAFHFHAVCETDSPNETWAGPKGRLSLDILREAVPDFLEREVFVCGPKPYMDAVR
AMLSQAGFDMARHHQESFDFGELPEAEQEAAAEAEKALDAEAAPAGGVRIFRVEFAKTRRVLECPENETVLDAARKAGIR
LPSSCAKGLCGTCKSKLTAGTVAMTHAGGIRQREIDAGMALLCCSKPTSDLVIER
>Mature_374_residues
APASSEPAARRLAASAPWDAEADDALVCLAVRDETHDVKTFVLAPKEPRLFAYAPGQFLTFSFEIGGETIHRCYTISSAP
TRPHAVSFTVKRVPGGPVSNWLHDTLKPGDTVRALGPMGEFSCFSHPAPKYLLLSGGSGVTPMMSMARSFHDLGEARDVA
FVHSARSPADIVFRGELETMARLDPAFHFHAVCETDSPNETWAGPKGRLSLDILREAVPDFLEREVFVCGPKPYMDAVRA
MLSQAGFDMARHHQESFDFGELPEAEQEAAAEAEKALDAEAAPAGGVRIFRVEFAKTRRVLECPENETVLDAARKAGIRL
PSSCAKGLCGTCKSKLTAGTVAMTHAGGIRQREIDAGMALLCCSKPTSDLVIER

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI84875541, Length=244, Percent_Identity=27.0491803278689, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI49574502, Length=245, Percent_Identity=28.1632653061224, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787098, Length=344, Percent_Identity=31.3953488372093, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1787658, Length=358, Percent_Identity=26.8156424581006, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788903, Length=247, Percent_Identity=27.5303643724696, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788104, Length=338, Percent_Identity=23.6686390532544, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322146, Length=223, Percent_Identity=27.3542600896861, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323552, Length=208, Percent_Identity=26.4423076923077, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323510, Length=169, Percent_Identity=27.2189349112426, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322699, Length=226, Percent_Identity=26.5486725663717, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40515; Mature: 40384

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPASSEPAARRLAASAPWDAEADDALVCLAVRDETHDVKTFVLAPKEPRLFAYAPGQFL
CCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEECCCCEE
TFSFEIGGETIHRCYTISSAPTRPHAVSFTVKRVPGGPVSNWLHDTLKPGDTVRALGPMG
EEEEEECCCEEEEEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEECCCCC
EFSCFSHPAPKYLLLSGGSGVTPMMSMARSFHDLGEARDVAFVHSARSPADIVFRGELET
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCHHH
MARLDPAFHFHAVCETDSPNETWAGPKGRLSLDILREAVPDFLEREVFVCGPKPYMDAVR
HHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
AMLSQAGFDMARHHQESFDFGELPEAEQEAAAEAEKALDAEAAPAGGVRIFRVEFAKTRR
HHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHCCH
VLECPENETVLDAARKAGIRLPSSCAKGLCGTCKSKLTAGTVAMTHAGGIRQREIDAGMA
HHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHCCCEE
LLCCSKPTSDLVIER
EEEECCCCCCCEECC
>Mature Secondary Structure 
APASSEPAARRLAASAPWDAEADDALVCLAVRDETHDVKTFVLAPKEPRLFAYAPGQFL
CCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEECCCCEE
TFSFEIGGETIHRCYTISSAPTRPHAVSFTVKRVPGGPVSNWLHDTLKPGDTVRALGPMG
EEEEEECCCEEEEEEEECCCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEECCCCC
EFSCFSHPAPKYLLLSGGSGVTPMMSMARSFHDLGEARDVAFVHSARSPADIVFRGELET
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCHHH
MARLDPAFHFHAVCETDSPNETWAGPKGRLSLDILREAVPDFLEREVFVCGPKPYMDAVR
HHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCHHHHHHH
AMLSQAGFDMARHHQESFDFGELPEAEQEAAAEAEKALDAEAAPAGGVRIFRVEFAKTRR
HHHHHHCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEHHHCCH
VLECPENETVLDAARKAGIRLPSSCAKGLCGTCKSKLTAGTVAMTHAGGIRQREIDAGMA
HHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHCCCEE
LLCCSKPTSDLVIER
EEEECCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]