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The map label for this gene is cmpB [H]

Identifier: 218531725

GI number: 218531725

Start: 4006400

End: 4007257

Strand: Reverse

Name: cmpB [H]

Synonym: Mchl_3794

Alternate gene names: 218531725

Gene position: 4007257-4006400 (Counterclockwise)

Preceding gene: 218531726

Following gene: 218531724

Centisome position: 69.35

GC content: 74.01

Gene sequence:

>858_bases
GTGAGCGGGGGCGTGATCGAGGCGGCGCTTGCCGTCGAGCGGGAGGTCGCGGCTCCCGCGCCGCGCCGGGCCGGGATCGG
TGCCCGGTTCGGTGCCTCTGCCCTCGACCGGCTGGCCCCACTCCTCGGCCTTGCGGGGCTGCTCGCCCTGTGGTTCGCGG
GCGGGCTGGTTCTGGAGAGCGTGCCGGCCTACGCCGCCTTTGCCGGTTTCGCGCCGGGGCCCGCGCTGGCCTCGTTCGTC
GAACTCCTGACCTCCGGCGAGGCGTGGCGGGCCGCGGCGCCGAGTCTCGCCCGGATCGGACAGGGCCTCGCCGTCGCCTT
CGGGCTCGGTGCGCCGCTCGGGCTACTGATCGGCTCGGTTCCGCTCGCCGAGCGCATCCTGCAGCCACCGTTCCAGCTCC
TGCGGATGATCTCGCCGCTGGCCTGGATGCCGGTGGCGGTGCTCGCCTTTCCGAGCTGGGACGGGGCCATCGTCTTCCTG
ATCGCCGCCGCTGCGATCTGGCCGATCCTGTTCGCCACCGCCGCCGGGGTGAAGCGGGTCGATCCGGTCTGGCTCGCCAT
GGCGCGCAACCTCGGCGCGGGCCGGCTCGCGGCTCTGCGCGCCGTCATCGTCCCGGCGGTGCTGCAGGACATCCTCACCG
GCCTGCGCCTCGCGCTCGGTGTTGCCTGGATCGTGCTGGTGCCGGCCGAGTATCTCGGGGTCACGAGCGGGCTCGGCTAC
GCCATCAACGACGCCCGCGACACCCTCTCCTACGACCGGCTCGCCGCCCTCGTCCTGCTGATCGGACTGATCGGCTACGC
CCTCGACACCGGTCTCGGGCGGCTGGCCGCCCGCGCCCGCTGGACTCCCGCAACCTGA

Upstream 100 bases:

>100_bases
TCGTCGACGACCGCTTCGTCCGGGCCTCGCTCAAGCGCTATCCCGAATGGCCGGGCGCGGCGGATGACGCCGCGCTCACC
CGCCAGGAGACCTTGAGCCT

Downstream 100 bases:

>100_bases
GGACACACACCATGACCGCGACCGCCGCCAAGGAAATCGTCCAGACCTTCGAGAAGGTGTTCGAGCCGATCGACCGCGAC
AAGCTGCACGCCCTCTCCGA

Product: binding-protein-dependent transporters inner membrane component

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSGGVIEAALAVEREVAAPAPRRAGIGARFGASALDRLAPLLGLAGLLALWFAGGLVLESVPAYAAFAGFAPGPALASFV
ELLTSGEAWRAAAPSLARIGQGLAVAFGLGAPLGLLIGSVPLAERILQPPFQLLRMISPLAWMPVAVLAFPSWDGAIVFL
IAAAAIWPILFATAAGVKRVDPVWLAMARNLGAGRLAALRAVIVPAVLQDILTGLRLALGVAWIVLVPAEYLGVTSGLGY
AINDARDTLSYDRLAALVLLIGLIGYALDTGLGRLAARARWTPAT

Sequences:

>Translated_285_residues
MSGGVIEAALAVEREVAAPAPRRAGIGARFGASALDRLAPLLGLAGLLALWFAGGLVLESVPAYAAFAGFAPGPALASFV
ELLTSGEAWRAAAPSLARIGQGLAVAFGLGAPLGLLIGSVPLAERILQPPFQLLRMISPLAWMPVAVLAFPSWDGAIVFL
IAAAAIWPILFATAAGVKRVDPVWLAMARNLGAGRLAALRAVIVPAVLQDILTGLRLALGVAWIVLVPAEYLGVTSGLGY
AINDARDTLSYDRLAALVLLIGLIGYALDTGLGRLAARARWTPAT
>Mature_284_residues
SGGVIEAALAVEREVAAPAPRRAGIGARFGASALDRLAPLLGLAGLLALWFAGGLVLESVPAYAAFAGFAPGPALASFVE
LLTSGEAWRAAAPSLARIGQGLAVAFGLGAPLGLLIGSVPLAERILQPPFQLLRMISPLAWMPVAVLAFPSWDGAIVFLI
AAAAIWPILFATAAGVKRVDPVWLAMARNLGAGRLAALRAVIVPAVLQDILTGLRLALGVAWIVLVPAEYLGVTSGLGYA
INDARDTLSYDRLAALVLLIGLIGYALDTGLGRLAARARWTPAT

Specific function: Part of the ABC transporter complex CmpABCD involved in bicarbonate transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=190, Percent_Identity=38.4210526315789, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081802, Length=216, Percent_Identity=33.7962962962963, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005889 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29292; Mature: 29161

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGVIEAALAVEREVAAPAPRRAGIGARFGASALDRLAPLLGLAGLLALWFAGGLVLES
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPAYAAFAGFAPGPALASFVELLTSGEAWRAAAPSLARIGQGLAVAFGLGAPLGLLIGSV
HHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHCCCHHHHHHCCCHHHHHHCCH
PLAERILQPPFQLLRMISPLAWMPVAVLAFPSWDGAIVFLIAAAAIWPILFATAAGVKRV
HHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHC
DPVWLAMARNLGAGRLAALRAVIVPAVLQDILTGLRLALGVAWIVLVPAEYLGVTSGLGY
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AINDARDTLSYDRLAALVLLIGLIGYALDTGLGRLAARARWTPAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SGGVIEAALAVEREVAAPAPRRAGIGARFGASALDRLAPLLGLAGLLALWFAGGLVLES
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPAYAAFAGFAPGPALASFVELLTSGEAWRAAAPSLARIGQGLAVAFGLGAPLGLLIGSV
HHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHCCCHHHHHHCCCHHHHHHCCH
PLAERILQPPFQLLRMISPLAWMPVAVLAFPSWDGAIVFLIAAAAIWPILFATAAGVKRV
HHHHHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHC
DPVWLAMARNLGAGRLAALRAVIVPAVLQDILTGLRLALGVAWIVLVPAEYLGVTSGLGY
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AINDARDTLSYDRLAALVLLIGLIGYALDTGLGRLAARARWTPAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]