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The map label for this gene is 218531551

Identifier: 218531551

GI number: 218531551

Start: 3810984

End: 3811658

Strand: Reverse

Name: 218531551

Synonym: Mchl_3619

Alternate gene names: NA

Gene position: 3811658-3810984 (Counterclockwise)

Preceding gene: 218531552

Following gene: 218531550

Centisome position: 65.97

GC content: 66.96

Gene sequence:

>675_bases
ATGACCCTCCCCGATCTCCGCTCCGGCAAAAGCTACGCCGTTTTTGACGCCTACGGCACGCTGTTCGATGTGCATTCGGC
GGTCGCGCGCCATGCCGGCGCGCTCGGACCTCAGGCGGACAGCCTCTCCGAGGTCTGGCGCACCAAGCAGCTCGAATATT
CCTGGGTGCACGGCCTGATGGGCCGCTACGTCGCCTTCTGGGACCTGACCGAGCGTGCCCTCGATTTCGCGCTGGCGAAG
CACCCCGAGATCGACCGGGGCTTTCGCGAAAAGCTCCTCGATGCCTATCGCGACCTCGACGCCTACGACGAGGTGCCCGG
CGTCCTGGAGCGTCTGCGCGAGCGCGGCGTGAAGACCGCGCTCTTCTCCAACGGCAATGCCGCGATGCTGGAGCGGGCGG
TGGCCTCCTCCGGCCTGGGCGAGCGGCTCGACGCAGTGCTCTCGGTCGATCCCGTCCGGACCTTCAAGACGGCGCCTGCC
GCCTACCAGATGGTTCTCGACCAACTCGCCACCGAACGGAACACCGTATTGTTCTTCTCCTCGAACCGCTGGGACATCGC
GGGGGCCACCGCCTTCGGCTTCGATGCGGTGTGGGTGAACCGGAAGGGACAGCCCGACGAGTACCCGGACCAGCCGCCTC
GCGCGGTCGTGAAGAGCCTCGACGCGGTGATCTGA

Upstream 100 bases:

>100_bases
GCTTACGCCGGCACCCTGCTCGCGGTGATGGGCGCGTTCGGCGTGCGATTGCGCCGCAGGTAGCCTTTCCGGATCGGGCG
GGCGCCTCATTTCACCTGGT

Downstream 100 bases:

>100_bases
ACCGCCGCAAGGGCGCGTTCGCCAATCCTTAAGCTTGACCGGATTAATTCGGGCTCACGTGCCTGATTAGTCCGGTTGTC
CAAAGGATCGGTTCTCGTGC

Product: haloacid dehalogenase, type II

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase I; DEHCI; Halocarboxylic acid halidohydrolase I; L-2-haloacid dehalogenase I [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MTLPDLRSGKSYAVFDAYGTLFDVHSAVARHAGALGPQADSLSEVWRTKQLEYSWVHGLMGRYVAFWDLTERALDFALAK
HPEIDRGFREKLLDAYRDLDAYDEVPGVLERLRERGVKTALFSNGNAAMLERAVASSGLGERLDAVLSVDPVRTFKTAPA
AYQMVLDQLATERNTVLFFSSNRWDIAGATAFGFDAVWVNRKGQPDEYPDQPPRAVVKSLDAVI

Sequences:

>Translated_224_residues
MTLPDLRSGKSYAVFDAYGTLFDVHSAVARHAGALGPQADSLSEVWRTKQLEYSWVHGLMGRYVAFWDLTERALDFALAK
HPEIDRGFREKLLDAYRDLDAYDEVPGVLERLRERGVKTALFSNGNAAMLERAVASSGLGERLDAVLSVDPVRTFKTAPA
AYQMVLDQLATERNTVLFFSSNRWDIAGATAFGFDAVWVNRKGQPDEYPDQPPRAVVKSLDAVI
>Mature_223_residues
TLPDLRSGKSYAVFDAYGTLFDVHSAVARHAGALGPQADSLSEVWRTKQLEYSWVHGLMGRYVAFWDLTERALDFALAKH
PEIDRGFREKLLDAYRDLDAYDEVPGVLERLRERGVKTALFSNGNAAMLERAVASSGLGERLDAVLSVDPVRTFKTAPAA
YQMVLDQLATERNTVLFFSSNRWDIAGATAFGFDAVWVNRKGQPDEYPDQPPRAVVKSLDAVI

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 24928; Mature: 24797

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPDLRSGKSYAVFDAYGTLFDVHSAVARHAGALGPQADSLSEVWRTKQLEYSWVHGLM
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHH
GRYVAFWDLTERALDFALAKHPEIDRGFREKLLDAYRDLDAYDEVPGVLERLRERGVKTA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
LFSNGNAAMLERAVASSGLGERLDAVLSVDPVRTFKTAPAAYQMVLDQLATERNTVLFFS
EECCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCEEEEEE
SNRWDIAGATAFGFDAVWVNRKGQPDEYPDQPPRAVVKSLDAVI
CCCCCCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TLPDLRSGKSYAVFDAYGTLFDVHSAVARHAGALGPQADSLSEVWRTKQLEYSWVHGLM
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHH
GRYVAFWDLTERALDFALAKHPEIDRGFREKLLDAYRDLDAYDEVPGVLERLRERGVKTA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
LFSNGNAAMLERAVASSGLGERLDAVLSVDPVRTFKTAPAAYQMVLDQLATERNTVLFFS
EECCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCEEEEEE
SNRWDIAGATAFGFDAVWVNRKGQPDEYPDQPPRAVVKSLDAVI
CCCCCCCCCHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1995594 [H]