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The map label for this gene is tlpA [H]

Identifier: 218531543

GI number: 218531543

Start: 3803578

End: 3804219

Strand: Reverse

Name: tlpA [H]

Synonym: Mchl_3611

Alternate gene names: 218531543

Gene position: 3804219-3803578 (Counterclockwise)

Preceding gene: 218531547

Following gene: 218531542

Centisome position: 65.84

GC content: 70.56

Gene sequence:

>642_bases
TTGAAGGCGACCCCGAAAATCCTTGCCGCCGGCGGCGCGCTCGCCGCCGTCCTCGTCGGCGGCCTCGCCCTATACGGGAC
GGGCTCGAACCTCGGCAACCTCGCGGCCTCCGGCCCCTGCGCCGAAGCCGCCCCGGTCGCGGCCCGGCTCGCGCCGCTGG
CCCGCGGCGACGTCGCCGCTTTCGACGCGTCCGCTCCCCCGAAGCCGGCACCCGCCGTCGCCTTCAAGGGCCCGGACGGC
GCGCCGACCGATCTCGCGTCCTTGCGCGGAAAACTGCTCCTGGTGAATCTGTGGGCGACGTGGTGCGCCCCCTGCAAGGC
GGAGATGCCGGCCCTCGATCGCCTTCAGGCGGAACTCGGCGGCGACAGCTTCCAAGTGGTGGCGATCAATGTCGAGACAC
GCAATCTCGACAAGCCGCCCGCATGGTTCAAGGCCAACGGCATCGCGCATCTGACCTATTACGGCGACCCCGAGGGCAAG
GTACTGCCAGTGATCCAGTCGGCGGTCGGCTCCACGGGGCTGCCGACGACGATGCTGATCGATGCCAAGGGCTGCACGCT
CGGCGTGATGAAGGGGCCGGCCGAATGGTCGAGCGAGGACGGCAAGCGGCTGATCCGGGCGGCGCTGGCGAAACCCTCCT
GA

Upstream 100 bases:

>100_bases
TCTCCTCCATGATCTCGGCCGGGCCGCTGGCGAAGCGTCCACCCCACATCCGGTTGCTCATGGCTGATCCCACCTTCCGC
ACGCGAAACGAGGTTCAGCC

Downstream 100 bases:

>100_bases
TTTTCCGAGGTGCCCGATTTTCCAAGCCAACGGGTTGCGGTGCCGGCCCGGGGCGGGCAACGGGTCACGGCATGAAGCCG
CCGCCCCCCTCCGTCCGTGC

Product: redoxin

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKATPKILAAGGALAAVLVGGLALYGTGSNLGNLAASGPCAEAAPVAARLAPLARGDVAAFDASAPPKPAPAVAFKGPDG
APTDLASLRGKLLLVNLWATWCAPCKAEMPALDRLQAELGGDSFQVVAINVETRNLDKPPAWFKANGIAHLTYYGDPEGK
VLPVIQSAVGSTGLPTTMLIDAKGCTLGVMKGPAEWSSEDGKRLIRAALAKPS

Sequences:

>Translated_213_residues
MKATPKILAAGGALAAVLVGGLALYGTGSNLGNLAASGPCAEAAPVAARLAPLARGDVAAFDASAPPKPAPAVAFKGPDG
APTDLASLRGKLLLVNLWATWCAPCKAEMPALDRLQAELGGDSFQVVAINVETRNLDKPPAWFKANGIAHLTYYGDPEGK
VLPVIQSAVGSTGLPTTMLIDAKGCTLGVMKGPAEWSSEDGKRLIRAALAKPS
>Mature_213_residues
MKATPKILAAGGALAAVLVGGLALYGTGSNLGNLAASGPCAEAAPVAARLAPLARGDVAAFDASAPPKPAPAVAFKGPDG
APTDLASLRGKLLLVNLWATWCAPCKAEMPALDRLQAELGGDSFQVVAINVETRNLDKPPAWFKANGIAHLTYYGDPEGK
VLPVIQSAVGSTGLPTTMLIDAKGCTLGVMKGPAEWSSEDGKRLIRAALAKPS

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21591; Mature: 21591

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATPKILAAGGALAAVLVGGLALYGTGSNLGNLAASGPCAEAAPVAARLAPLARGDVAA
CCCCCCEEECCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
FDASAPPKPAPAVAFKGPDGAPTDLASLRGKLLLVNLWATWCAPCKAEMPALDRLQAELG
ECCCCCCCCCCEEEEECCCCCCCCHHHHCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHC
GDSFQVVAINVETRNLDKPPAWFKANGIAHLTYYGDPEGKVLPVIQSAVGSTGLPTTMLI
CCEEEEEEEEEEECCCCCCCCEEECCCEEEEEEEECCCCCEEHHHHHHHCCCCCCEEEEE
DAKGCTLGVMKGPAEWSSEDGKRLIRAALAKPS
ECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKATPKILAAGGALAAVLVGGLALYGTGSNLGNLAASGPCAEAAPVAARLAPLARGDVAA
CCCCCCEEECCHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEE
FDASAPPKPAPAVAFKGPDGAPTDLASLRGKLLLVNLWATWCAPCKAEMPALDRLQAELG
ECCCCCCCCCCEEEEECCCCCCCCHHHHCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHC
GDSFQVVAINVETRNLDKPPAWFKANGIAHLTYYGDPEGKVLPVIQSAVGSTGLPTTMLI
CCEEEEEEEEEEECCCCCCCCEEECCCEEEEEEEECCCCCEEHHHHHHHCCCCCCEEEEE
DAKGCTLGVMKGPAEWSSEDGKRLIRAALAKPS
ECCCCEEEEECCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]