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The map label for this gene is exoB [H]

Identifier: 218531529

GI number: 218531529

Start: 3792061

End: 3793053

Strand: Reverse

Name: exoB [H]

Synonym: Mchl_3597

Alternate gene names: 218531529

Gene position: 3793053-3792061 (Counterclockwise)

Preceding gene: 218531531

Following gene: 218531528

Centisome position: 65.65

GC content: 67.57

Gene sequence:

>993_bases
ATGGCGGTTCTGGTCACGGGCGGCGCCGGCTATATCGGCAGCCACATGGTGCTCGCATTGGTTGATGCCGGGCATGAGGA
GGTCGTGGTCCTCGACGACCTCTCGACCGGTTACGATTGGGTCCTGCCGCCGGAAGTGCGTCTCGTCGTCGGCGACGTGG
CCGACCAAGCCCTCGTCACCGAGACCATTCTGCGCCACCAGATCGACACGGTCGCGCATTTCGCGGCCAAGATCGTCGTG
CCGGAATCGGTCGCCGACCCGCTCGGCTACTATCTCGCCAACACCGTGAAGACGCGCGCGCTGATCGAGACCGCGGTGCG
CACGAACGTCAAGCACTTCATCTTCTCCTCCACGGCGGCCGTCTACGGCGAGCCCGAGATCGTGCCGGTGCCCGAGACCC
TGACGCCGAACCCGATCAACCCCTACGGTCGCTCGAAGCTGATGAGCGAGTGGATGCTCGCGGATGCCGCCGCCGCGCAC
GGCTTCACCTACGGGGTGCTGCGCTACTTCAACGTGGCCGGGGCCGATCCGCGCGGGCGTTCCGGGCAATCGATGCCGGC
GGCCACCCACCTCATCAAGGTCGCGACGCAAGCAGCACTCGGTCAGCGCACGCATCTGGAGGTGTTCGGCACCGATTACC
CCACCCGCGACGGCTCGTGCCTGCGCGACTACATCCAGGTCTCGGATCTGGCCGCGGCGCATCTCACCGTCCTCGACTAT
CTGCGCGGCGGCGGCGACAGCCTGACCGTCAATTGCGGCTACGGCCGGGGCTACTCGGTTCTGGAAGTCGTGGAGGTGGT
CAAGCGCATCTCCGGCCGCGACTTCGAGGTGCGGCTGTCGCCCCGCCGGCCCGGCGATCCGGCTCAGATCATCGCCGGCG
CCGACCGCATCCGCAACGAACTCGGCTGGACCCCGAAGTACGACGACCTCGACGTCATCGTCGCCCAGGCGCTTGCCTGG
GAGGATACCCTGGCCAAGCGGAACCGGCGGTGA

Upstream 100 bases:

>100_bases
CCGCTAACAGCCCCGCTTGGGTTAGGATTGGCAGAATTTTGTCATAAGACGCGGCTGGCGCTTCAGCCGACGGCTGACGA
AGACGGATCAGGAGTGGACG

Downstream 100 bases:

>100_bases
GAGCACCCCGCGCCGCCGTCATCCTCGCACTCGCGCTGCTGGCGGGGCCGGCCCAGGCGCAGGATGGCGACTTCTCCGGC
TTCGTCGCGTCGCTGCGCCC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAVLVTGGAGYIGSHMVLALVDAGHEEVVVLDDLSTGYDWVLPPEVRLVVGDVADQALVTETILRHQIDTVAHFAAKIVV
PESVADPLGYYLANTVKTRALIETAVRTNVKHFIFSSTAAVYGEPEIVPVPETLTPNPINPYGRSKLMSEWMLADAAAAH
GFTYGVLRYFNVAGADPRGRSGQSMPAATHLIKVATQAALGQRTHLEVFGTDYPTRDGSCLRDYIQVSDLAAAHLTVLDY
LRGGGDSLTVNCGYGRGYSVLEVVEVVKRISGRDFEVRLSPRRPGDPAQIIAGADRIRNELGWTPKYDDLDVIVAQALAW
EDTLAKRNRR

Sequences:

>Translated_330_residues
MAVLVTGGAGYIGSHMVLALVDAGHEEVVVLDDLSTGYDWVLPPEVRLVVGDVADQALVTETILRHQIDTVAHFAAKIVV
PESVADPLGYYLANTVKTRALIETAVRTNVKHFIFSSTAAVYGEPEIVPVPETLTPNPINPYGRSKLMSEWMLADAAAAH
GFTYGVLRYFNVAGADPRGRSGQSMPAATHLIKVATQAALGQRTHLEVFGTDYPTRDGSCLRDYIQVSDLAAAHLTVLDY
LRGGGDSLTVNCGYGRGYSVLEVVEVVKRISGRDFEVRLSPRRPGDPAQIIAGADRIRNELGWTPKYDDLDVIVAQALAW
EDTLAKRNRR
>Mature_329_residues
AVLVTGGAGYIGSHMVLALVDAGHEEVVVLDDLSTGYDWVLPPEVRLVVGDVADQALVTETILRHQIDTVAHFAAKIVVP
ESVADPLGYYLANTVKTRALIETAVRTNVKHFIFSSTAAVYGEPEIVPVPETLTPNPINPYGRSKLMSEWMLADAAAAHG
FTYGVLRYFNVAGADPRGRSGQSMPAATHLIKVATQAALGQRTHLEVFGTDYPTRDGSCLRDYIQVSDLAAAHLTVLDYL
RGGGDSLTVNCGYGRGYSVLEVVEVVKRISGRDFEVRLSPRRPGDPAQIIAGADRIRNELGWTPKYDDLDVIVAQALAWE
DTLAKRNRR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=337, Percent_Identity=37.9821958456973, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI56118217, Length=337, Percent_Identity=37.9821958456973, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI189083684, Length=337, Percent_Identity=37.9821958456973, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI42516563, Length=313, Percent_Identity=27.1565495207668, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7657641, Length=323, Percent_Identity=26.0061919504644, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1786974, Length=315, Percent_Identity=42.8571428571429, Blast_Score=219, Evalue=3e-58,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=26.5486725663717, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=26.9461077844311, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=35.5882352941176, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=35.3801169590643, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17539532, Length=315, Percent_Identity=24.7619047619048, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17568069, Length=324, Percent_Identity=26.8518518518519, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=319, Percent_Identity=38.5579937304075, Blast_Score=202, Evalue=6e-53,
Organism=Drosophila melanogaster, GI19923002, Length=337, Percent_Identity=38.5756676557863, Blast_Score=205, Evalue=3e-53,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=28.0254777070064, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35824; Mature: 35693

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTGGAGYIGSHMVLALVDAGHEEVVVLDDLSTGYDWVLPPEVRLVVGDVADQALVT
CEEEEECCCCHHHHHHEEEEEECCCCEEEEEECCCCCCCEECCCCEEEEEECHHHHHHHH
ETILRHQIDTVAHFAAKIVVPESVADPLGYYLANTVKTRALIETAVRTNVKHFIFSSTAA
HHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VYGEPEIVPVPETLTPNPINPYGRSKLMSEWMLADAAAAHGFTYGVLRYFNVAGADPRGR
CCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
SGQSMPAATHLIKVATQAALGQRTHLEVFGTDYPTRDGSCLRDYIQVSDLAAAHLTVLDY
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRGGGDSLTVNCGYGRGYSVLEVVEVVKRISGRDFEVRLSPRRPGDPAQIIAGADRIRNE
HHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LGWTPKYDDLDVIVAQALAWEDTLAKRNRR
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVLVTGGAGYIGSHMVLALVDAGHEEVVVLDDLSTGYDWVLPPEVRLVVGDVADQALVT
EEEEECCCCHHHHHHEEEEEECCCCEEEEEECCCCCCCEECCCCEEEEEECHHHHHHHH
ETILRHQIDTVAHFAAKIVVPESVADPLGYYLANTVKTRALIETAVRTNVKHFIFSSTAA
HHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VYGEPEIVPVPETLTPNPINPYGRSKLMSEWMLADAAAAHGFTYGVLRYFNVAGADPRGR
CCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
SGQSMPAATHLIKVATQAALGQRTHLEVFGTDYPTRDGSCLRDYIQVSDLAAAHLTVLDY
CCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LRGGGDSLTVNCGYGRGYSVLEVVEVVKRISGRDFEVRLSPRRPGDPAQIIAGADRIRNE
HHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
LGWTPKYDDLDVIVAQALAWEDTLAKRNRR
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]