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The map label for this gene is pqqL [C]

Identifier: 218531509

GI number: 218531509

Start: 3766538

End: 3767833

Strand: Reverse

Name: pqqL [C]

Synonym: Mchl_3577

Alternate gene names: 218531509

Gene position: 3767833-3766538 (Counterclockwise)

Preceding gene: 218531510

Following gene: 218531508

Centisome position: 65.21

GC content: 70.52

Gene sequence:

>1296_bases
ATGAACCAGCATTTCTCGACCTTCGGCGCCTCGCCCGGCCTCACCGTCAGCCGGCTCGATAACGGCTTGACCGTCGCCAC
CGAGACGATCCCCGGCGTTGCCACGGCCACGCTCGGCGTCTGGGTCGGGGCGGGCTCGCGGCACGAACGGCCGGACGAGC
ACGGGCTCAGCCACCTGATCGAGCACATGGCCTTCAAGGGCACGGCGACGCGCTCGGCCCGGAAGATCGCCGAGGACATC
GAGAATGTCGGCGGTGAGATCAATGCCGCCACAAGCACCGAGAGCACGAGCTACACCGCGCGGGTGCTCGGCGAGGATGC
GGGCGTGGCGCTCGACGTGCTCGGCGACATCCTGACCCGCTCGGTCTTCGACGCCGGCGAACTTGCCCGCGAGAAGGGCG
TGATCCTTCAGGAATACGCGGCGGTCGAGGATACGCCCGACGACGTCGTCTACGACGCCTTCATCGAGACGGCTTTCCCC
GACCAGCCGATCGGCCGGCCGATCCTGGGCCGGCCCGAGACGATCCAGAGCTTCGACCGCGCGGCGATCGAGGCCTATAT
CGCCCGCGAATACGTTCCCGAGCGCATGGTGCTCGCCGCCGCCGGGGCGGTGGAGCATGCCGAGATCGTCGAGGCGGCCG
AGCGCCATTTCGGCGGCTTGAAGCCCGTCGCGGCCCCACCGGCCGTGGCCGGCGTCTACGGCGGCGGCGAGCGGCGGATG
CAGAAGCGGCTCGAACAGGCCAATCTGGTCCTCGGCCTGCCCGGTCTCTCCTTCCGTGATGACGGCTATTACGCGCTCCA
CCTGTTCTCGCAGGTGCTCGGCGGTGGTCTGACCTCGCGGCTCTGGCACGAGGTGCGCGAGACCCGCGGGCTCGCCTACG
ACATCCAGGCCTTCCACTGGCCCTTCAACGATTGCGGCCTGTTCGGCATCGGTGCCGGCACCTCGGGCGCGGATCTGGCC
GAACTCGTCGATGTCACCATCGCCACCACCCGTGAGGCGGCGGAGCGGCTCGACGCGGCCGAACTCGCCCGGGCCAAGGC
TCAGCTCAAGGTCTCCCTGCTCACCGCCCTGGAGACGCCGGGCGGGCGCATCGAGCGCAACGCCCGCCAGCTTCTCGCCT
GGGGTCGGGTGATCCCGCCGCAGGAGCTGATCGCCAAGGTCGATGCGGTCGAGGTCGAGCATGTGCGCGCGGCCGGCCGT
GCCCTGCTGCGCGGCGCCCCGACCCTGGCTGCGATCGGCCCGGTGAAGGGCTTGCCCTCGCTCGCACGCGTCGCGTCGGC
CCTTCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCACCTCAGGATGAGGATCAGGGTGGGAGGCCGGATCGACCGACCGTTTGTCCACCTCCGAAATACGTGGTGAGTTGGGC
CGAACAGGCACTGAGATCGA

Downstream 100 bases:

>100_bases
CGCCCAGCGCGTTCAGACATTGTGTCAGTCCGGCGCCGCGAACGGCGCCGGGCCCCGATCCCAGCGATAAAAACCGCCCG
CCATGAACCCCGTCGCCGTC

Product: processing peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MNQHFSTFGASPGLTVSRLDNGLTVATETIPGVATATLGVWVGAGSRHERPDEHGLSHLIEHMAFKGTATRSARKIAEDI
ENVGGEINAATSTESTSYTARVLGEDAGVALDVLGDILTRSVFDAGELAREKGVILQEYAAVEDTPDDVVYDAFIETAFP
DQPIGRPILGRPETIQSFDRAAIEAYIAREYVPERMVLAAAGAVEHAEIVEAAERHFGGLKPVAAPPAVAGVYGGGERRM
QKRLEQANLVLGLPGLSFRDDGYYALHLFSQVLGGGLTSRLWHEVRETRGLAYDIQAFHWPFNDCGLFGIGAGTSGADLA
ELVDVTIATTREAAERLDAAELARAKAQLKVSLLTALETPGGRIERNARQLLAWGRVIPPQELIAKVDAVEVEHVRAAGR
ALLRGAPTLAAIGPVKGLPSLARVASALQAA

Sequences:

>Translated_431_residues
MNQHFSTFGASPGLTVSRLDNGLTVATETIPGVATATLGVWVGAGSRHERPDEHGLSHLIEHMAFKGTATRSARKIAEDI
ENVGGEINAATSTESTSYTARVLGEDAGVALDVLGDILTRSVFDAGELAREKGVILQEYAAVEDTPDDVVYDAFIETAFP
DQPIGRPILGRPETIQSFDRAAIEAYIAREYVPERMVLAAAGAVEHAEIVEAAERHFGGLKPVAAPPAVAGVYGGGERRM
QKRLEQANLVLGLPGLSFRDDGYYALHLFSQVLGGGLTSRLWHEVRETRGLAYDIQAFHWPFNDCGLFGIGAGTSGADLA
ELVDVTIATTREAAERLDAAELARAKAQLKVSLLTALETPGGRIERNARQLLAWGRVIPPQELIAKVDAVEVEHVRAAGR
ALLRGAPTLAAIGPVKGLPSLARVASALQAA
>Mature_431_residues
MNQHFSTFGASPGLTVSRLDNGLTVATETIPGVATATLGVWVGAGSRHERPDEHGLSHLIEHMAFKGTATRSARKIAEDI
ENVGGEINAATSTESTSYTARVLGEDAGVALDVLGDILTRSVFDAGELAREKGVILQEYAAVEDTPDDVVYDAFIETAFP
DQPIGRPILGRPETIQSFDRAAIEAYIAREYVPERMVLAAAGAVEHAEIVEAAERHFGGLKPVAAPPAVAGVYGGGERRM
QKRLEQANLVLGLPGLSFRDDGYYALHLFSQVLGGGLTSRLWHEVRETRGLAYDIQAFHWPFNDCGLFGIGAGTSGADLA
ELVDVTIATTREAAERLDAAELARAKAQLKVSLLTALETPGGRIERNARQLLAWGRVIPPQELIAKVDAVEVEHVRAAGR
ALLRGAPTLAAIGPVKGLPSLARVASALQAA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=435, Percent_Identity=33.7931034482759, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI46593007, Length=443, Percent_Identity=29.3453724604966, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI24308013, Length=448, Percent_Identity=26.5625, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI50592988, Length=423, Percent_Identity=24.5862884160757, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1787770, Length=212, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=420, Percent_Identity=33.0952380952381, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17553678, Length=432, Percent_Identity=26.6203703703704, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17510601, Length=453, Percent_Identity=24.5033112582781, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323192, Length=438, Percent_Identity=34.2465753424658, Blast_Score=250, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6321813, Length=424, Percent_Identity=28.5377358490566, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319426, Length=447, Percent_Identity=24.6085011185682, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357875, Length=428, Percent_Identity=34.8130841121495, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24646943, Length=428, Percent_Identity=34.8130841121495, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI19921772, Length=450, Percent_Identity=25.3333333333333, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24665395, Length=419, Percent_Identity=24.582338902148, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45771; Mature: 45771

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQHFSTFGASPGLTVSRLDNGLTVATETIPGVATATLGVWVGAGSRHERPDEHGLSHLI
CCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCHHHHHHHHEECCCCCCCCCHHHHHHHHH
EHMAFKGTATRSARKIAEDIENVGGEINAATSTESTSYTARVLGEDAGVALDVLGDILTR
HHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
SVFDAGELAREKGVILQEYAAVEDTPDDVVYDAFIETAFPDQPIGRPILGRPETIQSFDR
HHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
AAIEAYIAREYVPERMVLAAAGAVEHAEIVEAAERHFGGLKPVAAPPAVAGVYGGGERRM
HHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHH
QKRLEQANLVLGLPGLSFRDDGYYALHLFSQVLGGGLTSRLWHEVRETRGLAYDIQAFHW
HHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHEEEC
PFNDCGLFGIGAGTSGADLAELVDVTIATTREAAERLDAAELARAKAQLKVSLLTALETP
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GGRIERNARQLLAWGRVIPPQELIAKVDAVEVEHVRAAGRALLRGAPTLAAIGPVKGLPS
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHH
LARVASALQAA
HHHHHHHHHCC
>Mature Secondary Structure
MNQHFSTFGASPGLTVSRLDNGLTVATETIPGVATATLGVWVGAGSRHERPDEHGLSHLI
CCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCHHHHHHHHEECCCCCCCCCHHHHHHHHH
EHMAFKGTATRSARKIAEDIENVGGEINAATSTESTSYTARVLGEDAGVALDVLGDILTR
HHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHH
SVFDAGELAREKGVILQEYAAVEDTPDDVVYDAFIETAFPDQPIGRPILGRPETIQSFDR
HHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
AAIEAYIAREYVPERMVLAAAGAVEHAEIVEAAERHFGGLKPVAAPPAVAGVYGGGERRM
HHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHH
QKRLEQANLVLGLPGLSFRDDGYYALHLFSQVLGGGLTSRLWHEVRETRGLAYDIQAFHW
HHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHEEEC
PFNDCGLFGIGAGTSGADLAELVDVTIATTREAAERLDAAELARAKAQLKVSLLTALETP
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GGRIERNARQLLAWGRVIPPQELIAKVDAVEVEHVRAAGRALLRGAPTLAAIGPVKGLPS
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHH
LARVASALQAA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA