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The map label for this gene is cobS [H]

Identifier: 218531486

GI number: 218531486

Start: 3741959

End: 3742942

Strand: Reverse

Name: cobS [H]

Synonym: Mchl_3554

Alternate gene names: 218531486

Gene position: 3742942-3741959 (Counterclockwise)

Preceding gene: 218531487

Following gene: 218531485

Centisome position: 64.78

GC content: 65.75

Gene sequence:

>984_bases
ATGCTGTCTGACGAAACGCCCGCTTCCCTGCCCGACCGCCAGGTTTCCGTCCGCGAGGTGTTCGGCATCGACCTCGACCT
GAAGGTGCCGGCCTATTCCGAGCCCGAGGAGCACGTGCCGGATCTCGATCCGGACTACATCTTCGACCGGGAGACGACGC
TGTCGATCCTGGCGGGCTTTGCGCGGAACCGCCGCGTGATGGTCAACGGCTATCACGGCACCGGCAAGTCGACGCATATC
GAGCAGGTCGCGGCACGGCTGAACTGGCCCTGTATCCGGATCAACCTCGACAGCCACGTCTCGCGCATCGACCTCGTCGG
CAAGGACGCCATCGTCCTGAAGGACGGCAAGCAGGTCACGGCCTTCCAGGACGGCATCCTGCCCTGGGCCCTGCAGAACA
ATGTCGCGCTCGTCTTCGACGAGTACGATGCCGGCCGCCCCGACGTGATGTTCGTGATCCAGCGCGTGCTGGAGCTCTCC
GGCCGCCTGACGCTGCTCGACCAGAAGCGGGTCATCCGCCCGCATCCGGGCTTCCGCCTGTTCGCCACCGCCAACACGGT
CGGCCTCGGCGACACGTCCGGCCTCTATCACGGCACCCAGCAGATCAACCAGGGTCAGATGGACCGCTGGTCGATCGTGA
CCACGCTGAACTACCTGCCGCACGACCGCGAGGTCGACATCGTGCTCTCGAAGTCGCCGCACTACCAGAGCGAGGGCGGG
CGCGACACCGTGAGCCGGATGGTGCGCGTGGCCGATCTGACCCGCAACGCGTTCATGAACGGCGACCTCTCGACCGTCAT
GAGCCCGCGCACGGTCATCACCTGGGCCGAGAACGCCGACATCTTCCGCGATATCGGCTTCGCCTTCCGGGTGACGTTCC
TCAACAAGTGCGACGAGCTGGAACGGCCCCTGGTGGCCGAGTTCTACCAACGCGCCTTCGGCAAGGAACTGCCCGAGAGC
GCGCTCAACGTCGCCTTGAGCTGA

Upstream 100 bases:

>100_bases
TCCGCCCGCTTCCCTGTGGGCCGCCCGGCAGGTGAGTGACGATTGAAAGCGCGGTCGCGCGGGTTCACGCCTGCTCCCGG
CCGCCCCGATGAGGTTCCGT

Downstream 100 bases:

>100_bases
CCTGACGGTGCCGTCCCCGCCCGCGCCCGGCGTGCGGCGGGGACGGCGCCCCTCTCCCCGTGACCGGGGGCGATCCCCCG
GCCGGGCCTCCGAACTCGAT

Product: cobalt chelatase, pCobS small subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MLSDETPASLPDRQVSVREVFGIDLDLKVPAYSEPEEHVPDLDPDYIFDRETTLSILAGFARNRRVMVNGYHGTGKSTHI
EQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLKDGKQVTAFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELS
GRLTLLDQKRVIRPHPGFRLFATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKSPHYQSEGG
RDTVSRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFRDIGFAFRVTFLNKCDELERPLVAEFYQRAFGKELPES
ALNVALS

Sequences:

>Translated_327_residues
MLSDETPASLPDRQVSVREVFGIDLDLKVPAYSEPEEHVPDLDPDYIFDRETTLSILAGFARNRRVMVNGYHGTGKSTHI
EQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLKDGKQVTAFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELS
GRLTLLDQKRVIRPHPGFRLFATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKSPHYQSEGG
RDTVSRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFRDIGFAFRVTFLNKCDELERPLVAEFYQRAFGKELPES
ALNVALS
>Mature_327_residues
MLSDETPASLPDRQVSVREVFGIDLDLKVPAYSEPEEHVPDLDPDYIFDRETTLSILAGFARNRRVMVNGYHGTGKSTHI
EQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLKDGKQVTAFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELS
GRLTLLDQKRVIRPHPGFRLFATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKSPHYQSEGG
RDTVSRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFRDIGFAFRVTFLNKCDELERPLVAEFYQRAFGKELPES
ALNVALS

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=242, Percent_Identity=23.5537190082645, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076560, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076562, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 36801; Mature: 36801

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSDETPASLPDRQVSVREVFGIDLDLKVPAYSEPEEHVPDLDPDYIFDRETTLSILAGF
CCCCCCCCCCCCCCEEHHHHHCCCEEEECCCCCCCHHHCCCCCCCCEECCCHHHHHHHHH
ARNRRVMVNGYHGTGKSTHIEQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLKDGKQVT
HCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEEE
AFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELSGRLTLLDQKRVIRPHPGFRL
EHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEE
FATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKSPHYQSEGG
EEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCCCCC
RDTVSRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFRDIGFAFRVTFLNKCDEL
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ERPLVAEFYQRAFGKELPESALNVALS
CCCHHHHHHHHHHCCCCCHHHHHEECC
>Mature Secondary Structure
MLSDETPASLPDRQVSVREVFGIDLDLKVPAYSEPEEHVPDLDPDYIFDRETTLSILAGF
CCCCCCCCCCCCCCEEHHHHHCCCEEEECCCCCCCHHHCCCCCCCCEECCCHHHHHHHHH
ARNRRVMVNGYHGTGKSTHIEQVAARLNWPCIRINLDSHVSRIDLVGKDAIVLKDGKQVT
HCCCEEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEEE
AFQDGILPWALQNNVALVFDEYDAGRPDVMFVIQRVLELSGRLTLLDQKRVIRPHPGFRL
EHHCCCCCEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEE
FATANTVGLGDTSGLYHGTQQINQGQMDRWSIVTTLNYLPHDREVDIVLSKSPHYQSEGG
EEECCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEHHCCCCCCCEEEEEECCCCCCCCCC
RDTVSRMVRVADLTRNAFMNGDLSTVMSPRTVITWAENADIFRDIGFAFRVTFLNKCDEL
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ERPLVAEFYQRAFGKELPESALNVALS
CCCHHHHHHHHHHCCCCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]