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The map label for this gene is cobT [H]

Identifier: 218531485

GI number: 218531485

Start: 3739931

End: 3741838

Strand: Reverse

Name: cobT [H]

Synonym: Mchl_3553

Alternate gene names: 218531485

Gene position: 3741838-3739931 (Counterclockwise)

Preceding gene: 218531486

Following gene: 218531484

Centisome position: 64.76

GC content: 70.23

Gene sequence:

>1908_bases
ATGGCCCTGACCAACCGCCCCAAGACCGGCGACCGCAAGGAGCCCGGCGCCGAGCCGCTGAAGCGCTCGGTGGCCGGCTG
CCTGCGCGCCATCGCCAAGCGGCCCGACATCGAGGTCACCTATGCCAGCGATCGGCCGGCGCTGATCGGCGACAAGGCGC
GCCTGCCGGAGCCGACCCGGCGGATCACCGCCGAGGACGCGGCGATCCTGCGCGGGCATTCCGATTCCATGGCCCTGCGC
CTCGGCTGCCACGACACCAGCGTCCACCGCCGCCTCGCCCCCGACAACGCAGCCGCCCGCGCGGTCTACGACGCGGTCGA
GCAGGCGCGCGTCGAGGCGATCGGTTCGCGCCGCCTGGAAGGCGTGGCCGCCAACATCACCGCGATGCTGGAGGACCGCT
ACCACCGCGGCGGCAAGTACGAGAACATCACCGACCGGGCCGACGCGCCGATGGAGGATGCCGTCGCGCTGATGGTGCGC
GAGCGCCTCACCGGCCAGAAGCCGCCGCCCGCCGCCGCCCGGATCGTCGAGCTGTGGCGCGAACATATCGAGGCACGCGC
CGGCAAGAACCTCGACGGATTGCTCGGCTCGCTTGAGAACCAGCGCCACTTCGCCCGCTCCGTGCGCGACCTCCTCTCCT
CCCTCGACATGGCCGACGAGACGCCCCTCGATCAGGACGATGAGAGCGACGAGGACGAGAACCAAGCCCAGGACGACGAG
CAGCAGCCGAGCGAGGGCGAGGCGGAGGAGCAGAGCCAGGGCGACCGCGCCGAGATCGAGGTGACCGACGAGGCCACCGA
CGAACTCGACGAGGGCGCCACAGAATCCGCCGACGCTCCCTCCGGCGAGCTGCCGGAGGAAGCCGAGGACGCCGAGTCGG
AGGAGGCCTCCGAATCCTGGCGCCCGCCGAGCCAGCGCGGCAACGAGCGCACCGGCCCCGACTACAAGGTCTACAACCCG
CGCTTCGACGAGACCGTCGAGGCCGAGGATCTGTGCGACGCCGAGGAACTCGCGCGCCTGCGCAGCTATCTCGACAAGCA
GCTCGCCCACCTCCAGGGCGTCGTCGGCCGCCTCGCCAACCGTCTCCAGCGCCGCCTGCTGGCGCAGCAGAGCCGCGCCT
GGGATTTCGATCTCGAAGAGGGCCAGCTCGATCCGGCCCGCCTCGTTCGCGTCGTCACCGATCCGTTTCAGCCGCTCTCC
TTCAAGCAGGAGAAGGACACCGACTTCCGCGACACGGTGGTCACGCTGCTGCTCGACAATTCCGGTTCGATGCGTGGGCG
CCCGATCACCGTGGCCGCGACCTGCGCCGACATTCTCGCGCGCACGCTGGAGCGCTGCGGCGTGAAGGTCGAGATTCTCG
GCTTCACCACCCGCGCCTGGAAGGGCGGCCAGTCCCGCGAGGCGTGGCTTGCCGGCGGCAAGCCGCCCGCCCCCGGCCGC
CTCAACGACCTGCGTCACATCATCTACAAGAGCGCCGACGCCCCCTGGCGCCGTGCGCGAAAGAACCTCGGGCTGATGAT
GCGCGAGGGGCTCCTGAAGGAGAACATCGACGGCGAGGCACTGGATTGGGCCCACAAGCGCCTGCTGGCGCGGCCCGAGC
AGCGCCGCATCCTGATGGTGATTTCCGATGGTGCGCCGGTCGACGACTCGACGCTCTCGGTCAATCCCGGCAACTACCTC
GAGCGCCACCTGCGCTACATGATCGAGGAGATCGAGACCCGCTCACCGGTCGAACTTCTGGCCATCGGCATCGGCCACGA
CGTGACGCGCTACTACCGCCGTGCCGTGACGATCATCGACGCCGAGGAACTCGGCGGCGCGATGACGGAAAAGCTCGCCG
AGCTGTTCGAGGAGAACACGGGCGCGTCGCGCGGCGGCGGGATGAAGCGGGTCGCCGGTCGGCGCTGA

Upstream 100 bases:

>100_bases
CCGCGCCCGGCGTGCGGCGGGGACGGCGCCCCTCTCCCCGTGACCGGGGGCGATCCCCCGGCCGGGCCTCCGAACTCGAT
CCGGTGGCGTCCGCGAAGAT

Downstream 100 bases:

>100_bases
ACGGGCGGTTGTTCGGAGCGGTAAAGCTCCGGTTGGCAAGTGGTCATCGTCGTCCTACCGTGTGGAAGCGTTGCCTCCAG
CGAGGACCTTCCGATGTCAG

Product: cobalt chelatase, pCobT subunit

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobT [H]

Number of amino acids: Translated: 635; Mature: 634

Protein sequence:

>635_residues
MALTNRPKTGDRKEPGAEPLKRSVAGCLRAIAKRPDIEVTYASDRPALIGDKARLPEPTRRITAEDAAILRGHSDSMALR
LGCHDTSVHRRLAPDNAAARAVYDAVEQARVEAIGSRRLEGVAANITAMLEDRYHRGGKYENITDRADAPMEDAVALMVR
ERLTGQKPPPAAARIVELWREHIEARAGKNLDGLLGSLENQRHFARSVRDLLSSLDMADETPLDQDDESDEDENQAQDDE
QQPSEGEAEEQSQGDRAEIEVTDEATDELDEGATESADAPSGELPEEAEDAESEEASESWRPPSQRGNERTGPDYKVYNP
RFDETVEAEDLCDAEELARLRSYLDKQLAHLQGVVGRLANRLQRRLLAQQSRAWDFDLEEGQLDPARLVRVVTDPFQPLS
FKQEKDTDFRDTVVTLLLDNSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTRAWKGGQSREAWLAGGKPPAPGR
LNDLRHIIYKSADAPWRRARKNLGLMMREGLLKENIDGEALDWAHKRLLARPEQRRILMVISDGAPVDDSTLSVNPGNYL
ERHLRYMIEEIETRSPVELLAIGIGHDVTRYYRRAVTIIDAEELGGAMTEKLAELFEENTGASRGGGMKRVAGRR

Sequences:

>Translated_635_residues
MALTNRPKTGDRKEPGAEPLKRSVAGCLRAIAKRPDIEVTYASDRPALIGDKARLPEPTRRITAEDAAILRGHSDSMALR
LGCHDTSVHRRLAPDNAAARAVYDAVEQARVEAIGSRRLEGVAANITAMLEDRYHRGGKYENITDRADAPMEDAVALMVR
ERLTGQKPPPAAARIVELWREHIEARAGKNLDGLLGSLENQRHFARSVRDLLSSLDMADETPLDQDDESDEDENQAQDDE
QQPSEGEAEEQSQGDRAEIEVTDEATDELDEGATESADAPSGELPEEAEDAESEEASESWRPPSQRGNERTGPDYKVYNP
RFDETVEAEDLCDAEELARLRSYLDKQLAHLQGVVGRLANRLQRRLLAQQSRAWDFDLEEGQLDPARLVRVVTDPFQPLS
FKQEKDTDFRDTVVTLLLDNSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTRAWKGGQSREAWLAGGKPPAPGR
LNDLRHIIYKSADAPWRRARKNLGLMMREGLLKENIDGEALDWAHKRLLARPEQRRILMVISDGAPVDDSTLSVNPGNYL
ERHLRYMIEEIETRSPVELLAIGIGHDVTRYYRRAVTIIDAEELGGAMTEKLAELFEENTGASRGGGMKRVAGRR
>Mature_634_residues
ALTNRPKTGDRKEPGAEPLKRSVAGCLRAIAKRPDIEVTYASDRPALIGDKARLPEPTRRITAEDAAILRGHSDSMALRL
GCHDTSVHRRLAPDNAAARAVYDAVEQARVEAIGSRRLEGVAANITAMLEDRYHRGGKYENITDRADAPMEDAVALMVRE
RLTGQKPPPAAARIVELWREHIEARAGKNLDGLLGSLENQRHFARSVRDLLSSLDMADETPLDQDDESDEDENQAQDDEQ
QPSEGEAEEQSQGDRAEIEVTDEATDELDEGATESADAPSGELPEEAEDAESEEASESWRPPSQRGNERTGPDYKVYNPR
FDETVEAEDLCDAEELARLRSYLDKQLAHLQGVVGRLANRLQRRLLAQQSRAWDFDLEEGQLDPARLVRVVTDPFQPLSF
KQEKDTDFRDTVVTLLLDNSGSMRGRPITVAATCADILARTLERCGVKVEILGFTTRAWKGGQSREAWLAGGKPPAPGRL
NDLRHIIYKSADAPWRRARKNLGLMMREGLLKENIDGEALDWAHKRLLARPEQRRILMVISDGAPVDDSTLSVNPGNYLE
RHLRYMIEEIETRSPVELLAIGIGHDVTRYYRRAVTIIDAEELGGAMTEKLAELFEENTGASRGGGMKRVAGRR

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG4547

COG function: function code H; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006538
- InterPro:   IPR002035 [H]

Pfam domain/function: PF06213 CobT [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 70664; Mature: 70532

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTNRPKTGDRKEPGAEPLKRSVAGCLRAIAKRPDIEVTYASDRPALIGDKARLPEPTR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEECCCCCCCCHHH
RITAEDAAILRGHSDSMALRLGCHDTSVHRRLAPDNAAARAVYDAVEQARVEAIGSRRLE
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVAANITAMLEDRYHRGGKYENITDRADAPMEDAVALMVRERLTGQKPPPAAARIVELWR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EHIEARAGKNLDGLLGSLENQRHFARSVRDLLSSLDMADETPLDQDDESDEDENQAQDDE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCC
QQPSEGEAEEQSQGDRAEIEVTDEATDELDEGATESADAPSGELPEEAEDAESEEASESW
CCCCCCCCHHHCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCCCCCHHHHCHHHHHHHHC
RPPSQRGNERTGPDYKVYNPRFDETVEAEDLCDAEELARLRSYLDKQLAHLQGVVGRLAN
CCCHHCCCCCCCCCCEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRRLLAQQSRAWDFDLEEGQLDPARLVRVVTDPFQPLSFKQEKDTDFRDTVVTLLLDN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEECC
SGSMRGRPITVAATCADILARTLERCGVKVEILGFTTRAWKGGQSREAWLAGGKPPAPGR
CCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEHHHCCCCCCCCHHCCCCCCCCCCH
LNDLRHIIYKSADAPWRRARKNLGLMMREGLLKENIDGEALDWAHKRLLARPEQRRILMV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEE
ISDGAPVDDSTLSVNPGNYLERHLRYMIEEIETRSPVELLAIGIGHDVTRYYRRAVTIID
EECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCHHHEEECCCHHHHHHHHHHHHEEE
AEELGGAMTEKLAELFEENTGASRGGGMKRVAGRR
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
ALTNRPKTGDRKEPGAEPLKRSVAGCLRAIAKRPDIEVTYASDRPALIGDKARLPEPTR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEECCCCCCCCHHH
RITAEDAAILRGHSDSMALRLGCHDTSVHRRLAPDNAAARAVYDAVEQARVEAIGSRRLE
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GVAANITAMLEDRYHRGGKYENITDRADAPMEDAVALMVRERLTGQKPPPAAARIVELWR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
EHIEARAGKNLDGLLGSLENQRHFARSVRDLLSSLDMADETPLDQDDESDEDENQAQDDE
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCC
QQPSEGEAEEQSQGDRAEIEVTDEATDELDEGATESADAPSGELPEEAEDAESEEASESW
CCCCCCCCHHHCCCCCEEEEECCCHHHHHHCCCCCCCCCCCCCCCCHHHHCHHHHHHHHC
RPPSQRGNERTGPDYKVYNPRFDETVEAEDLCDAEELARLRSYLDKQLAHLQGVVGRLAN
CCCHHCCCCCCCCCCEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRRLLAQQSRAWDFDLEEGQLDPARLVRVVTDPFQPLSFKQEKDTDFRDTVVTLLLDN
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHEEEEEECC
SGSMRGRPITVAATCADILARTLERCGVKVEILGFTTRAWKGGQSREAWLAGGKPPAPGR
CCCCCCCCEEHHHHHHHHHHHHHHHCCCEEEEEEEEHHHCCCCCCCCHHCCCCCCCCCCH
LNDLRHIIYKSADAPWRRARKNLGLMMREGLLKENIDGEALDWAHKRLLARPEQRRILMV
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEE
ISDGAPVDDSTLSVNPGNYLERHLRYMIEEIETRSPVELLAIGIGHDVTRYYRRAVTIID
EECCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCHHHEEECCCHHHHHHHHHHHHEEE
AEELGGAMTEKLAELFEENTGASRGGGMKRVAGRR
HHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]