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The map label for this gene is katX [H]

Identifier: 218531466

GI number: 218531466

Start: 3719082

End: 3720674

Strand: Reverse

Name: katX [H]

Synonym: Mchl_3534

Alternate gene names: 218531466

Gene position: 3720674-3719082 (Counterclockwise)

Preceding gene: 218531470

Following gene: 218531458

Centisome position: 64.39

GC content: 66.23

Gene sequence:

>1593_bases
ATGAGCGAGAACCGTCCGATTCTGACGACCCGTCAGGGCCATCCGGTCCGCGACAACCAGAGCACGCGCACGGTCGGCGA
GCGGGGCCCGGCAACGCTCGAGAACTACCAGTTCATCGAGAAGATCACCCATTTCGACCGCGAGCGCATTCCGGAGCGCG
TGGTGCATGCCCGCGGTGCCGGCGCCCATGGCTGGTTTGAGGCCTATGGCAAGATCGGCGACGAGCCCGCGTCCAAGTAC
ACCCGCGCCCGCGTGCTGAACGAGACCGGCGTGAAGACGCCGATGTTTGTGCGCTTCTCCACCGTGGCCGGCGCCAAGGA
GAGCCCTGAGACCGAGCGCGACCCGCGCGGCTTCGCGGTGAAGTTCAAGACCGTCGACGGCAATTGGGACCTCGTGGGCA
ACAACCTCAAGGTCTTCTTCATCCGCGACGCGATCAAGTTCCCCGACATGATCCACGCGTTCAAGCCGGACCCGGTGACG
AACCGCCAGGAGGCGTGGCGCTTCTTCGACTTCGTGGCCCAGCACCCCGAAGCGATCCACATGGTCACCCACCTGAAGTC
GCCTTGGGGCATTCCGGCCAACTATCGCGAGATGGAAGGCTCGGGCGTCAACACCTACAAGCTGGTCAACGACCAGGGCG
AGGCGGTGCTCTGCAAGTTCCACTGGGAGCCCAAGCAGGGCGTGCGCAACCTGACCTCGGCCCAGGCGTCCGAGATCCAG
GCCAAGGATGTCGGCCACGCGACGCGTGACCTCTACGACAACATCAAGGCCGGCAATTTCCCCGAGTGGGAATTCTGCGT
GCAGATCATGCCCGACGGCCCGAACGACCACCTGTCGTTCGATCCGCTCGACGACACGAAGCTGTGGCCGGTCGAGGATT
TCCCGCTGCTGCCGGTCGGCCGCATGGTGCTGGACCGCGTGCCGGACAACTTCTTCGCGGAAGTCGAGCAGTCGGCCTTC
GGCACGGGCGTGCTCGTGGACGGCATCGACTTCTCGGACGACAAGATGCTCCAGGGCCGGACGCTGTCCTACTCGGACAC
GCAGCGCTACCGCGTCGGCGCCAACTACCTGCAGCTGCCGATCAACGCGCCGCAGCCCGGCGTGAAGGTCTATTCGAACC
AGCGCGACGGCCAGATGACCTACAGCGTCGATGGCACCGGCCCGAACCGCCACATCAACTACGAGCCCTCGACGCTCGCC
GAGGGCCTGCGCGAGGCGCCCAAGCCGGCCAAGGATTACCACCAGCCGGTCCAGGGCAATCTCGGCCGCTACCAGACCTC
GCGGACCGAGGATGACTACACCCAGGCCGGCGTTCGCTACCGCTCGTTCCAGGATTGGGAGCGTGAGGATCTGATCGCCA
ACCTCGTGGCCGACATGAAGCAGTGCCCCGAGCCGATCCAGCTTCGGATGGTCTGGCACTTCTGGCACGCCGACGAGGAT
TACGGCCGCCGCGTTGCCGAGGGCGCCGGGATCGATCTGGAGAAGGCCAAGGCCCTGCCGCCGCTGCCGGGCCGTGCCGC
CCCGCATAAGCGCCTCCAGGCCGAGACCTACACCGACGGCAGCACCGCCGCGCACAAGGTCGCCGCCGAGTAA

Upstream 100 bases:

>100_bases
CATGCCTGGGTCATACCATCGAAACAGAATGGTTCCAGGCTGTGCGGACGCGCCGAGCGATCCACCCTGAAGCCCCTGCC
TCCCAAGGAGAGAGTGACGC

Downstream 100 bases:

>100_bases
GGCGAACGGCCGAACGACGTAAAAAAACCCCGCTCGACCATCCGGTCGGGCGGGGTTTCTTTTTGGAAGAGGCGGGAGCC
CCAAGCTGAGGCTCCCGTCG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MSENRPILTTRQGHPVRDNQSTRTVGERGPATLENYQFIEKITHFDRERIPERVVHARGAGAHGWFEAYGKIGDEPASKY
TRARVLNETGVKTPMFVRFSTVAGAKESPETERDPRGFAVKFKTVDGNWDLVGNNLKVFFIRDAIKFPDMIHAFKPDPVT
NRQEAWRFFDFVAQHPEAIHMVTHLKSPWGIPANYREMEGSGVNTYKLVNDQGEAVLCKFHWEPKQGVRNLTSAQASEIQ
AKDVGHATRDLYDNIKAGNFPEWEFCVQIMPDGPNDHLSFDPLDDTKLWPVEDFPLLPVGRMVLDRVPDNFFAEVEQSAF
GTGVLVDGIDFSDDKMLQGRTLSYSDTQRYRVGANYLQLPINAPQPGVKVYSNQRDGQMTYSVDGTGPNRHINYEPSTLA
EGLREAPKPAKDYHQPVQGNLGRYQTSRTEDDYTQAGVRYRSFQDWEREDLIANLVADMKQCPEPIQLRMVWHFWHADED
YGRRVAEGAGIDLEKAKALPPLPGRAAPHKRLQAETYTDGSTAAHKVAAE

Sequences:

>Translated_530_residues
MSENRPILTTRQGHPVRDNQSTRTVGERGPATLENYQFIEKITHFDRERIPERVVHARGAGAHGWFEAYGKIGDEPASKY
TRARVLNETGVKTPMFVRFSTVAGAKESPETERDPRGFAVKFKTVDGNWDLVGNNLKVFFIRDAIKFPDMIHAFKPDPVT
NRQEAWRFFDFVAQHPEAIHMVTHLKSPWGIPANYREMEGSGVNTYKLVNDQGEAVLCKFHWEPKQGVRNLTSAQASEIQ
AKDVGHATRDLYDNIKAGNFPEWEFCVQIMPDGPNDHLSFDPLDDTKLWPVEDFPLLPVGRMVLDRVPDNFFAEVEQSAF
GTGVLVDGIDFSDDKMLQGRTLSYSDTQRYRVGANYLQLPINAPQPGVKVYSNQRDGQMTYSVDGTGPNRHINYEPSTLA
EGLREAPKPAKDYHQPVQGNLGRYQTSRTEDDYTQAGVRYRSFQDWEREDLIANLVADMKQCPEPIQLRMVWHFWHADED
YGRRVAEGAGIDLEKAKALPPLPGRAAPHKRLQAETYTDGSTAAHKVAAE
>Mature_529_residues
SENRPILTTRQGHPVRDNQSTRTVGERGPATLENYQFIEKITHFDRERIPERVVHARGAGAHGWFEAYGKIGDEPASKYT
RARVLNETGVKTPMFVRFSTVAGAKESPETERDPRGFAVKFKTVDGNWDLVGNNLKVFFIRDAIKFPDMIHAFKPDPVTN
RQEAWRFFDFVAQHPEAIHMVTHLKSPWGIPANYREMEGSGVNTYKLVNDQGEAVLCKFHWEPKQGVRNLTSAQASEIQA
KDVGHATRDLYDNIKAGNFPEWEFCVQIMPDGPNDHLSFDPLDDTKLWPVEDFPLLPVGRMVLDRVPDNFFAEVEQSAFG
TGVLVDGIDFSDDKMLQGRTLSYSDTQRYRVGANYLQLPINAPQPGVKVYSNQRDGQMTYSVDGTGPNRHINYEPSTLAE
GLREAPKPAKDYHQPVQGNLGRYQTSRTEDDYTQAGVRYRSFQDWEREDLIANLVADMKQCPEPIQLRMVWHFWHADEDY
GRRVAEGAGIDLEKAKALPPLPGRAAPHKRLQAETYTDGSTAAHKVAAE

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=481, Percent_Identity=44.0748440748441, Blast_Score=391, Evalue=1e-108,
Organism=Escherichia coli, GI48994891, Length=498, Percent_Identity=41.7670682730924, Blast_Score=361, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI25147792, Length=479, Percent_Identity=44.4676409185804, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI25151141, Length=479, Percent_Identity=44.4676409185804, Blast_Score=409, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI71998444, Length=480, Percent_Identity=43.75, Blast_Score=404, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6320462, Length=496, Percent_Identity=37.2983870967742, Blast_Score=294, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6321525, Length=515, Percent_Identity=32.4271844660194, Blast_Score=255, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17981717, Length=482, Percent_Identity=42.9460580912863, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI19920968, Length=489, Percent_Identity=40.4907975460123, Blast_Score=379, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 60016; Mature: 59885

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENRPILTTRQGHPVRDNQSTRTVGERGPATLENYQFIEKITHFDRERIPERVVHARGA
CCCCCCEEEECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAHGWFEAYGKIGDEPASKYTRARVLNETGVKTPMFVRFSTVAGAKESPETERDPRGFAV
CCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
KFKTVDGNWDLVGNNLKVFFIRDAIKFPDMIHAFKPDPVTNRQEAWRFFDFVAQHPEAIH
EEEEECCCEEEECCCEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHH
MVTHLKSPWGIPANYREMEGSGVNTYKLVNDQGEAVLCKFHWEPKQGVRNLTSAQASEIQ
HHHHCCCCCCCCCCHHHCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
AKDVGHATRDLYDNIKAGNFPEWEFCVQIMPDGPNDHLSFDPLDDTKLWPVEDFPLLPVG
HHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RMVLDRVPDNFFAEVEQSAFGTGVLVDGIDFSDDKMLQGRTLSYSDTQRYRVGANYLQLP
HHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCEECCCCCCCCCCCCEEECCCEEEEE
INAPQPGVKVYSNQRDGQMTYSVDGTGPNRHINYEPSTLAEGLREAPKPAKDYHQPVQGN
CCCCCCCCEEECCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHCCCCHHHHCCCCCCC
LGRYQTSRTEDDYTQAGVRYRSFQDWEREDLIANLVADMKQCPEPIQLRMVWHFWHADED
CCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHH
YGRRVAEGAGIDLEKAKALPPLPGRAAPHKRLQAETYTDGSTAAHKVAAE
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure 
SENRPILTTRQGHPVRDNQSTRTVGERGPATLENYQFIEKITHFDRERIPERVVHARGA
CCCCCEEEECCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GAHGWFEAYGKIGDEPASKYTRARVLNETGVKTPMFVRFSTVAGAKESPETERDPRGFAV
CCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCEEE
KFKTVDGNWDLVGNNLKVFFIRDAIKFPDMIHAFKPDPVTNRQEAWRFFDFVAQHPEAIH
EEEEECCCEEEECCCEEEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHH
MVTHLKSPWGIPANYREMEGSGVNTYKLVNDQGEAVLCKFHWEPKQGVRNLTSAQASEIQ
HHHHCCCCCCCCCCHHHCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
AKDVGHATRDLYDNIKAGNFPEWEFCVQIMPDGPNDHLSFDPLDDTKLWPVEDFPLLPVG
HHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RMVLDRVPDNFFAEVEQSAFGTGVLVDGIDFSDDKMLQGRTLSYSDTQRYRVGANYLQLP
HHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCEECCCCCCCCCCCCEEECCCEEEEE
INAPQPGVKVYSNQRDGQMTYSVDGTGPNRHINYEPSTLAEGLREAPKPAKDYHQPVQGN
CCCCCCCCEEECCCCCCEEEEEECCCCCCCEECCCHHHHHHHHHHCCCCHHHHCCCCCCC
LGRYQTSRTEDDYTQAGVRYRSFQDWEREDLIANLVADMKQCPEPIQLRMVWHFWHADED
CCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCHH
YGRRVAEGAGIDLEKAKALPPLPGRAAPHKRLQAETYTDGSTAAHKVAAE
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]