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The map label for this gene is atpB [H]

Identifier: 218531431

GI number: 218531431

Start: 3682473

End: 3683228

Strand: Reverse

Name: atpB [H]

Synonym: Mchl_3499

Alternate gene names: 218531431

Gene position: 3683228-3682473 (Counterclockwise)

Preceding gene: 218531432

Following gene: 218531430

Centisome position: 63.75

GC content: 65.08

Gene sequence:

>756_bases
ATGGCGGTCAGTATCGACCCGATCCACCAGTTCGAGCTGCAGCCGCTCGTCTCGCTGGGTCACATCGGCAACCAGCAGCT
CGCGTTCACGCAATCGGCTCTGTACATGTTCGCCGCGGTGGGCATCATCGCGCTGCTGACCATCGTGGCGACCTCCGGGC
GTTCCGTGGTTCCGGGCCGTCTCCAGGCGCTGGCCGAGACGCTCTACGAATTCATCGCCGATACAGTGCACCAAGCGACC
GGCGAGGACGGCAAGCGCTTCCTGCCGCTCGTGTTCTCCCTGTTCATGTTCGTGCTCATTCTGAACCTGCTCGGGATGAT
CCCCTACGCCTTCGCGGTGACCAGCCACCTCATCGTCACCTTCGGCCTCGCGCTGGTCGTGATCCTGACCGTGGTGATCT
ACGGCGTCGCCAAGCACGGCACCCACTTCCTCGGCGTGTTCGTGCCATCGGGCGTGCCGAAGCCGCTGCTGCTCATCATG
GTGCCGATCGAGATCGTGTCGTTCCTGTCGCGGCCGATCAGCCTCTCGGTTCGTCTCTTCGCCAACATCCTGGCCGGCCA
CATCGCGCTGAAGATCTTCGCCTTCTTCGTGGTCCAGCTGCTGGTTGCCGGCGCTTGGGGCGTGCTGTCGCCCCTGCCGC
TCGCGCTCACCATCGCGCTGACGGCTCTCGAGTTCCTCGTCGCGGCCCTTCAGGCTTACGTCTTCGCGACGCTGACGGCG
GTCTACCTCGCCGACGCCCTCCACCCCGGCCACTGA

Upstream 100 bases:

>100_bases
GGGTCTTGAGACTCGCCCGGCATCGTGTAAGGGCGACGCGCGACAGACGGGAGCCGCAAAGGCTTCCTCGCGCGACACAC
AAAGGGGCGGAAGCGGGCAC

Downstream 100 bases:

>100_bases
TCCGTCCCGGCCGGACCCTTCCGCCCTCAACGAACCCCGTTCGAACTTCAGGAGTGTTTCATGGATCCCGTCGCTGCGAA
GTACATCGGCGCCGGTCTCG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MAVSIDPIHQFELQPLVSLGHIGNQQLAFTQSALYMFAAVGIIALLTIVATSGRSVVPGRLQALAETLYEFIADTVHQAT
GEDGKRFLPLVFSLFMFVLILNLLGMIPYAFAVTSHLIVTFGLALVVILTVVIYGVAKHGTHFLGVFVPSGVPKPLLLIM
VPIEIVSFLSRPISLSVRLFANILAGHIALKIFAFFVVQLLVAGAWGVLSPLPLALTIALTALEFLVAALQAYVFATLTA
VYLADALHPGH

Sequences:

>Translated_251_residues
MAVSIDPIHQFELQPLVSLGHIGNQQLAFTQSALYMFAAVGIIALLTIVATSGRSVVPGRLQALAETLYEFIADTVHQAT
GEDGKRFLPLVFSLFMFVLILNLLGMIPYAFAVTSHLIVTFGLALVVILTVVIYGVAKHGTHFLGVFVPSGVPKPLLLIM
VPIEIVSFLSRPISLSVRLFANILAGHIALKIFAFFVVQLLVAGAWGVLSPLPLALTIALTALEFLVAALQAYVFATLTA
VYLADALHPGH
>Mature_250_residues
AVSIDPIHQFELQPLVSLGHIGNQQLAFTQSALYMFAAVGIIALLTIVATSGRSVVPGRLQALAETLYEFIADTVHQATG
EDGKRFLPLVFSLFMFVLILNLLGMIPYAFAVTSHLIVTFGLALVVILTVVIYGVAKHGTHFLGVFVPSGVPKPLLLIMV
PIEIVSFLSRPISLSVRLFANILAGHIALKIFAFFVVQLLVAGAWGVLSPLPLALTIALTALEFLVAALQAYVFATLTAV
YLADALHPGH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Homo sapiens, GI251831112, Length=215, Percent_Identity=31.1627906976744, Blast_Score=84, Evalue=9e-17,
Organism=Escherichia coli, GI1790176, Length=219, Percent_Identity=26.9406392694064, Blast_Score=64, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6226527, Length=251, Percent_Identity=36.6533864541833, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 26882; Mature: 26750

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCCC
>Mature Secondary Structure 
AVSIDPIHQFELQPLVSLGHIGNQQLAFTQSALYMFAAVGIIALLTIVATSGRSVVPGR
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
LQALAETLYEFIADTVHQATGEDGKRFLPLVFSLFMFVLILNLLGMIPYAFAVTSHLIVT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLALVVILTVVIYGVAKHGTHFLGVFVPSGVPKPLLLIMVPIEIVSFLSRPISLSVRLF
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ANILAGHIALKIFAFFVVQLLVAGAWGVLSPLPLALTIALTALEFLVAALQAYVFATLTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYLADALHPGH
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA