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The map label for this gene is cynT [H]

Identifier: 218531004

GI number: 218531004

Start: 3229066

End: 3229842

Strand: Reverse

Name: cynT [H]

Synonym: Mchl_3054

Alternate gene names: 218531004

Gene position: 3229842-3229066 (Counterclockwise)

Preceding gene: 218531005

Following gene: 218531003

Centisome position: 55.9

GC content: 66.92

Gene sequence:

>777_bases
GTGGTGACAGCGGGGTTTGACGTGGACGGCATCATCCAAGGTCTGTCGAACTTCCGGGGAACGGTCTTTCCGGGCCAGCA
GCAGATGTATCAGCGGCTGGTGCGTGACGGTCAGCAGCCCAAGGCGCTCATGATCGCCTGCGCCGATTCCCGCGTCTCGC
CCGAGCACATCACGCAGTCCGGTCCCGGCGATCTGTTCGTATGCCGGAATGCCGGCAACATCGTACCGCCCTTCTCGCAG
CAGAACGGCGGCGTGTCCTCCGCGATCGAGTACGCGGTCGTCGCGCTCGGCGTGCTGGACATCGTGATCTGCGGTCATTC
CGATTGCGGCGCCATGAAGGGGCTCATGAATCCCGAGGCGCTGGGCAACATGCCCAACGTGGCGGCGTGGCTGCGCCACA
GCCATGCGGCGAAACAGATCGTCTGCGAGGCCTATCCCGAGGGCATGGACCCGAAGGAGCGCCACCGCGCCGTCGGCCTC
GAGAATGTCGTGGTGCAGCTCAACCATCTGCGTACCCACCCGAGCGTGGCGACGGCTCTGGCCCGCGGCAAGCTGCGCCT
GCACGGCTGGTTCTTCGAAATCGAGAGCGGCCAGGTGCTCGCCTATTGCGGCGAGCGCGGTCGCTTCATCCCCATCGACG
AAGCCACGGGCGTCCCCGTCGCCCAGGCTTCGGCGTCGCGGATCGCCACACCGGAATTCGCCGGCCCCCATGCTGGTCCC
CATGCCAGCCCCCATGCCGGGTCCGAACCCATCCCCCACGCTATCGCAGCGGAGTAG

Upstream 100 bases:

>100_bases
GCATCACCGCGTCTCGCCCGATCAGACTTCGCGGATCGACAGGCGTGATGCGCGTGTCATCCAGCCAGCATCTCATGCGT
CGCGGCGTGTCGGCTCACGC

Downstream 100 bases:

>100_bases
ATTTTTGCTATGCGCGCCTCCCTCGCCCGGCTGATGCCATCGACCATCGGCCGGGATCTTCCGGCCTCCTTCGTCGTCTT
CCTCGTGGCGATGCCCCTCT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 1 [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MVTAGFDVDGIIQGLSNFRGTVFPGQQQMYQRLVRDGQQPKALMIACADSRVSPEHITQSGPGDLFVCRNAGNIVPPFSQ
QNGGVSSAIEYAVVALGVLDIVICGHSDCGAMKGLMNPEALGNMPNVAAWLRHSHAAKQIVCEAYPEGMDPKERHRAVGL
ENVVVQLNHLRTHPSVATALARGKLRLHGWFFEIESGQVLAYCGERGRFIPIDEATGVPVAQASASRIATPEFAGPHAGP
HASPHAGSEPIPHAIAAE

Sequences:

>Translated_258_residues
MVTAGFDVDGIIQGLSNFRGTVFPGQQQMYQRLVRDGQQPKALMIACADSRVSPEHITQSGPGDLFVCRNAGNIVPPFSQ
QNGGVSSAIEYAVVALGVLDIVICGHSDCGAMKGLMNPEALGNMPNVAAWLRHSHAAKQIVCEAYPEGMDPKERHRAVGL
ENVVVQLNHLRTHPSVATALARGKLRLHGWFFEIESGQVLAYCGERGRFIPIDEATGVPVAQASASRIATPEFAGPHAGP
HASPHAGSEPIPHAIAAE
>Mature_258_residues
MVTAGFDVDGIIQGLSNFRGTVFPGQQQMYQRLVRDGQQPKALMIACADSRVSPEHITQSGPGDLFVCRNAGNIVPPFSQ
QNGGVSSAIEYAVVALGVLDIVICGHSDCGAMKGLMNPEALGNMPNVAAWLRHSHAAKQIVCEAYPEGMDPKERHRAVGL
ENVVVQLNHLRTHPSVATALARGKLRLHGWFFEIESGQVLAYCGERGRFIPIDEATGVPVAQASASRIATPEFAGPHAGP
HASPHAGSEPIPHAIAAE

Specific function: Reversible hydration of carbon dioxide. Carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (CynS) diffuses out of the cell faster than it would be hydrated to bicarbonate, so the apparent function of this enzyme is to c

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=219, Percent_Identity=44.7488584474886, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1786318, Length=198, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25147564, Length=259, Percent_Identity=28.1853281853282, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI115532990, Length=249, Percent_Identity=26.5060240963855, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324292, Length=187, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24645213, Length=243, Percent_Identity=27.9835390946502, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 27406; Mature: 27406

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTAGFDVDGIIQGLSNFRGTVFPGQQQMYQRLVRDGQQPKALMIACADSRVSPEHITQS
CEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCC
GPGDLFVCRNAGNIVPPFSQQNGGVSSAIEYAVVALGVLDIVICGHSDCGAMKGLMNPEA
CCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHH
LGNMPNVAAWLRHSHAAKQIVCEAYPEGMDPKERHRAVGLENVVVQLNHLRTHPSVATAL
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
ARGKLRLHGWFFEIESGQVLAYCGERGRFIPIDEATGVPVAQASASRIATPEFAGPHAGP
HHCCEEEEEEEEEECCCCEEEEECCCCCEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCC
HASPHAGSEPIPHAIAAE
CCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MVTAGFDVDGIIQGLSNFRGTVFPGQQQMYQRLVRDGQQPKALMIACADSRVSPEHITQS
CEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCC
GPGDLFVCRNAGNIVPPFSQQNGGVSSAIEYAVVALGVLDIVICGHSDCGAMKGLMNPEA
CCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHH
LGNMPNVAAWLRHSHAAKQIVCEAYPEGMDPKERHRAVGLENVVVQLNHLRTHPSVATAL
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
ARGKLRLHGWFFEIESGQVLAYCGERGRFIPIDEATGVPVAQASASRIATPEFAGPHAGP
HHCCEEEEEEEEEECCCCEEEEECCCCCEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCC
HASPHAGSEPIPHAIAAE
CCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]