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The map label for this gene is ttuD [H]

Identifier: 218530924

GI number: 218530924

Start: 3136927

End: 3138240

Strand: Reverse

Name: ttuD [H]

Synonym: Mchl_2974

Alternate gene names: 218530924

Gene position: 3138240-3136927 (Counterclockwise)

Preceding gene: 218530928

Following gene: 218530923

Centisome position: 54.31

GC content: 71.46

Gene sequence:

>1314_bases
ATGACCGCCCCTGCCCCGACCGATCCGGCCCACGCGGAGCGTCGCGCCCTCCTTTCGTCGATCCTCGATGAGGCGATCGC
CGCCGCCCATCCGCGCAAGTGCCTCGTCGGGCACCTGCCGGCCCCGACGCCGGGGCGGCTGATCATTCTCGGTGCGGGCA
AGGCCGGCGGCAGCATGGCCGCGGTGGCGAGCAAGTTTTACCGCCAGGAGCACGGAGTGCCGGAGGACCGGATCGTCGGT
CTCGCCGTGGCCCGGCACGGTTACGGCGAGGAGGCTCCCGGCATTCGCATGGTCGAGGCCGGCCACCCGGTTCCCGATGC
GGCCGGCATCGAGGCGACCAAGGAAGCCCTCGCCATCGCCGCGAGCGCGGGCCCGGAGGACGAGGTCCTGGTACTGCTCT
CCGGCGGCGGCTCGGCGAACTGGATCGCGCCTGCCGGCAACCTGACGCTCGCGGAGAAGCAGGCGATCACCAAGGCTTTG
CTGCGCTCGGGTGCGCCGATCAACGAGATCAACGCCGTGCGCAAGCACCTCTCGCGCATCAAGGGCGGCCGGCTCGCAAT
GGCGGCACGCAACGCCAAGTCGATTCTGACCCTCGCCATCTCCGACGTGCCGCATGACGATCCGTCCGTGATCGCCTCCG
GCCCGACCGTGCCCGATCCCTCGACCCTGGCCGATGCCCGCGCGATCTGCGAACGCCGCGGCATCAGCCTGCCCGAATCC
GCGCTCGCCCTGCTGAACGATCCGGCCAACGAGACGCCGAAGGCGGGCGATCCGGCCTTCGCCCGGGCCGAGTACCGCAT
CATCGCCCGGCCGATCGACGCGCTCGAAGCGGCGGCCGAGGCCGCCCGGCGGGCCGGCTACGAGCCGGTGATGCTGGGCT
CCGATCTTGAGGGCGAGGCCCGCGAGGTCGCGGCCGAACATGCCCGGCTGGCGCTCGAGGCGCGGCAGGCGGGGCGTCGC
GTCGCCCTGATCTCCGGCGGCGAACTCACCGTCACCATTCGCGGCGAAGGCGATGGCGGCCCCAATCAGGAATATGCGCT
GGCGCTCGCCATCGCGCTCGATGGAGCCGAGGGCATCGCCGGCATCGCCGCCGATACCGACGGCACCGATGGCGGGCGCG
GCGCGGCGACCGACCCCGCGGGCGGCTTGGTCGACGCCACGACGCTGACCCGCGCCGAGGCTGCAGGGCTCGATCCGAAA
GCGATGCTGCTCGACAACGATTCGACGCGATTCTTCGCGACAACCGGCGATCTCGTTCAGCCGGGCCCTACTCGGACCAA
TGTCAACGATTGCCGCGTCATCCTCGTCGGTTGA

Upstream 100 bases:

>100_bases
ACCCGAAAGTTTTGTGAAACCGCGAAGGCTTGCCGACACGGCAGCGCTCGGGCAAGCAAACGCACAAACAAGAACCGTCA
AGACCCGCGCGAGGACGCCC

Downstream 100 bases:

>100_bases
GTTCCTGACAGCATCGTCCCAAAAGGCGGCCACCGGCTTTTGGAAGAAGACGATGCAGAAACTAGCGAGAGCGCGCTCGC
GGCGCAGGGCCGTCCTCGGG

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTAPAPTDPAHAERRALLSSILDEAIAAAHPRKCLVGHLPAPTPGRLIILGAGKAGGSMAAVASKFYRQEHGVPEDRIVG
LAVARHGYGEEAPGIRMVEAGHPVPDAAGIEATKEALAIAASAGPEDEVLVLLSGGGSANWIAPAGNLTLAEKQAITKAL
LRSGAPINEINAVRKHLSRIKGGRLAMAARNAKSILTLAISDVPHDDPSVIASGPTVPDPSTLADARAICERRGISLPES
ALALLNDPANETPKAGDPAFARAEYRIIARPIDALEAAAEAARRAGYEPVMLGSDLEGEAREVAAEHARLALEARQAGRR
VALISGGELTVTIRGEGDGGPNQEYALALAIALDGAEGIAGIAADTDGTDGGRGAATDPAGGLVDATTLTRAEAAGLDPK
AMLLDNDSTRFFATTGDLVQPGPTRTNVNDCRVILVG

Sequences:

>Translated_437_residues
MTAPAPTDPAHAERRALLSSILDEAIAAAHPRKCLVGHLPAPTPGRLIILGAGKAGGSMAAVASKFYRQEHGVPEDRIVG
LAVARHGYGEEAPGIRMVEAGHPVPDAAGIEATKEALAIAASAGPEDEVLVLLSGGGSANWIAPAGNLTLAEKQAITKAL
LRSGAPINEINAVRKHLSRIKGGRLAMAARNAKSILTLAISDVPHDDPSVIASGPTVPDPSTLADARAICERRGISLPES
ALALLNDPANETPKAGDPAFARAEYRIIARPIDALEAAAEAARRAGYEPVMLGSDLEGEAREVAAEHARLALEARQAGRR
VALISGGELTVTIRGEGDGGPNQEYALALAIALDGAEGIAGIAADTDGTDGGRGAATDPAGGLVDATTLTRAEAAGLDPK
AMLLDNDSTRFFATTGDLVQPGPTRTNVNDCRVILVG
>Mature_436_residues
TAPAPTDPAHAERRALLSSILDEAIAAAHPRKCLVGHLPAPTPGRLIILGAGKAGGSMAAVASKFYRQEHGVPEDRIVGL
AVARHGYGEEAPGIRMVEAGHPVPDAAGIEATKEALAIAASAGPEDEVLVLLSGGGSANWIAPAGNLTLAEKQAITKALL
RSGAPINEINAVRKHLSRIKGGRLAMAARNAKSILTLAISDVPHDDPSVIASGPTVPDPSTLADARAICERRGISLPESA
LALLNDPANETPKAGDPAFARAEYRIIARPIDALEAAAEAARRAGYEPVMLGSDLEGEAREVAAEHARLALEARQAGRRV
ALISGGELTVTIRGEGDGGPNQEYALALAIALDGAEGIAGIAADTDGTDGGRGAATDPAGGLVDATTLTRAEAAGLDPKA
MLLDNDSTRFFATTGDLVQPGPTRTNVNDCRVILVG

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=382, Percent_Identity=33.2460732984293, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI193205461, Length=360, Percent_Identity=30.5555555555556, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19920578, Length=399, Percent_Identity=30.5764411027569, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44644; Mature: 44513

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPAPTDPAHAERRALLSSILDEAIAAAHPRKCLVGHLPAPTPGRLIILGAGKAGGSMA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCEEEEEECCCCCCHHH
AVASKFYRQEHGVPEDRIVGLAVARHGYGEEAPGIRMVEAGHPVPDAAGIEATKEALAIA
HHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHEEE
ASAGPEDEVLVLLSGGGSANWIAPAGNLTLAEKQAITKALLRSGAPINEINAVRKHLSRI
ECCCCCCCEEEEEECCCCCCEECCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
KGGRLAMAARNAKSILTLAISDVPHDDPSVIASGPTVPDPSTLADARAICERRGISLPES
CCCEEEEECCCCCEEEEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCHH
ALALLNDPANETPKAGDPAFARAEYRIIARPIDALEAAAEAARRAGYEPVMLGSDLEGEA
HHHHHCCCCCCCCCCCCCCHHHCCEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCCCHH
REVAAEHARLALEARQAGRRVALISGGELTVTIRGEGDGGPNQEYALALAIALDGAEGIA
HHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCE
GIAADTDGTDGGRGAATDPAGGLVDATTLTRAEAAGLDPKAMLLDNDSTRFFATTGDLVQ
EEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCC
PGPTRTNVNDCRVILVG
CCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
TAPAPTDPAHAERRALLSSILDEAIAAAHPRKCLVGHLPAPTPGRLIILGAGKAGGSMA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCCCCEEEEEECCCCCCHHH
AVASKFYRQEHGVPEDRIVGLAVARHGYGEEAPGIRMVEAGHPVPDAAGIEATKEALAIA
HHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHEEE
ASAGPEDEVLVLLSGGGSANWIAPAGNLTLAEKQAITKALLRSGAPINEINAVRKHLSRI
ECCCCCCCEEEEEECCCCCCEECCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
KGGRLAMAARNAKSILTLAISDVPHDDPSVIASGPTVPDPSTLADARAICERRGISLPES
CCCEEEEECCCCCEEEEEEEECCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCHH
ALALLNDPANETPKAGDPAFARAEYRIIARPIDALEAAAEAARRAGYEPVMLGSDLEGEA
HHHHHCCCCCCCCCCCCCCHHHCCEEEEECCHHHHHHHHHHHHHCCCCCEEECCCCCCHH
REVAAEHARLALEARQAGRRVALISGGELTVTIRGEGDGGPNQEYALALAIALDGAEGIA
HHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCCCEEEEEEEEECCCCCCE
GIAADTDGTDGGRGAATDPAGGLVDATTLTRAEAAGLDPKAMLLDNDSTRFFATTGDLVQ
EEECCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCC
PGPTRTNVNDCRVILVG
CCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]