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The map label for this gene is atpB [H]

Identifier: 218711029

GI number: 218711029

Start: 3293581

End: 3294378

Strand: Reverse

Name: atpB [H]

Synonym: VS_3158

Alternate gene names: 218711029

Gene position: 3294378-3293581 (Counterclockwise)

Preceding gene: 218711030

Following gene: 218711028

Centisome position: 99.85

GC content: 40.73

Gene sequence:

>798_bases
ATGGCTGCGCCAACAGCATCCGGATACATTGAACACCATTTACAAAACCTTTCTTTAGCTAAGTTTGGTCTTGTAGAGGA
GACAAGTTTCTGGAACGTACATATAGACAGTCTGTTTTTTTCGGTGTTGACAGGGATGTTATTCCTTTGGGTTTTTCGCT
CAGTCGCTAAGAAAGCAACAGTAGGTGTACCTGGTAAGCTTCAGTGTTTTGTTGAAATGGTAGTGGAATTCGTTGGTGAC
AACGTTAAAGAAACTTTCCATGGCCGCAACCCTCTGATTGCCCCACTAGCACTGACTATATTCTGCTGGATTATCATTAT
GAACTTGATGGACTTAGTGCCTATCGATTTCTTACCATATCCTGCAGAGCATTGGCTAGGTATCCCTTACTTGAAAGTGG
TTCCTACAGCTGATGTTAATATAACAATGGCAATGGCTTTAGGTGTTTTTGCTCTGATGATCTACTACAGCATCAAAGTG
AAAGGTCTAGGCGGATTTGCTAAAGAATTGGCACTGCATCCATTTAATCACCCAATCATGATTCCATTTAACTTGGTACT
TGAGGTAATTTCGTTATTAGCGAAGCCACTATCTCTAGGTATGCGTTTATTTGGTAATATGTTTGCGGGTGAGGTGGTGT
TTATTCTTATCGCGGCAATGCTACCGTGGTACTTACAATGGGTAGGTGCACTACCTTGGGCTATCTTCCATATCTTGGTT
ATTTTGATTCAAGCGTTTGTTTTCATGATGTTGACAATCGTTTACTTATCAATGGCTCATGAAGATAGTGATCACTAA

Upstream 100 bases:

>100_bases
AGGTGGAATTAATTCCCCTCAAACTGACCTATTTACTGGTTCTAGGTATTAATATCTTTGCGCCAGTGCTTTTCATTAAC
AATAAAAAATAGGATGAGTT

Downstream 100 bases:

>100_bases
AAAATTTTTAAGCTTTATTCTAACTATTAATGTTAATCGGAGAACGTAAATGGAAACTGTACTAAGTTTTTCAGCAATCG
CTGTTGCTATCATTGTTGGT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAAPTASGYIEHHLQNLSLAKFGLVEETSFWNVHIDSLFFSVLTGMLFLWVFRSVAKKATVGVPGKLQCFVEMVVEFVGD
NVKETFHGRNPLIAPLALTIFCWIIIMNLMDLVPIDFLPYPAEHWLGIPYLKVVPTADVNITMAMALGVFALMIYYSIKV
KGLGGFAKELALHPFNHPIMIPFNLVLEVISLLAKPLSLGMRLFGNMFAGEVVFILIAAMLPWYLQWVGALPWAIFHILV
ILIQAFVFMMLTIVYLSMAHEDSDH

Sequences:

>Translated_265_residues
MAAPTASGYIEHHLQNLSLAKFGLVEETSFWNVHIDSLFFSVLTGMLFLWVFRSVAKKATVGVPGKLQCFVEMVVEFVGD
NVKETFHGRNPLIAPLALTIFCWIIIMNLMDLVPIDFLPYPAEHWLGIPYLKVVPTADVNITMAMALGVFALMIYYSIKV
KGLGGFAKELALHPFNHPIMIPFNLVLEVISLLAKPLSLGMRLFGNMFAGEVVFILIAAMLPWYLQWVGALPWAIFHILV
ILIQAFVFMMLTIVYLSMAHEDSDH
>Mature_264_residues
AAPTASGYIEHHLQNLSLAKFGLVEETSFWNVHIDSLFFSVLTGMLFLWVFRSVAKKATVGVPGKLQCFVEMVVEFVGDN
VKETFHGRNPLIAPLALTIFCWIIIMNLMDLVPIDFLPYPAEHWLGIPYLKVVPTADVNITMAMALGVFALMIYYSIKVK
GLGGFAKELALHPFNHPIMIPFNLVLEVISLLAKPLSLGMRLFGNMFAGEVVFILIAAMLPWYLQWVGALPWAIFHILVI
LIQAFVFMMLTIVYLSMAHEDSDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=264, Percent_Identity=63.2575757575758, Blast_Score=327, Evalue=7e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29742; Mature: 29611

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AAPTASGYIEHHLQNLSLAKFGLVEETSFWNVHIDSLFFSVLTGMLFLWVFRSVAKKAT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VGVPGKLQCFVEMVVEFVGDNVKETFHGRNPLIAPLALTIFCWIIIMNLMDLVPIDFLPY
CCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAEHWLGIPYLKVVPTADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHPIM
CHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHCCCCCCCEE
IPFNLVLEVISLLAKPLSLGMRLFGNMFAGEVVFILIAAMLPWYLQWVGALPWAIFHILV
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILIQAFVFMMLTIVYLSMAHEDSDH
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA