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The map label for this gene is trkA [H]

Identifier: 218711001

GI number: 218711001

Start: 3264836

End: 3266212

Strand: Direct

Name: trkA [H]

Synonym: VS_3129

Alternate gene names: 218711001

Gene position: 3264836-3266212 (Clockwise)

Preceding gene: 218711000

Following gene: 218711002

Centisome position: 98.96

GC content: 49.16

Gene sequence:

>1377_bases
ATGAAGATCATTATTCTAGGTGCTGGACAAGTTGGCGGTACCCTTGCTGAAAACCTAGTGGGTGAAAACAATGACATCAC
GATCGTCGACCGTAATGCCGACCGACTGCGTGAACTTCAGGACAAATACGACCTTAGGGTTGTAAACGGTTATGCCAGCC
ACCCGAACACACTACGTGAAGCGGGCGCGCAAGATGCCGACATGTTGGTTGCCGTAACCAACATGGATGAAACCAACATG
GCCGCATGTCAGGTTGCCTTCTCTCTGTTTAACACGCCAAACCGTATTGCTCGTATTCGTTCTCCTCAATACCTAGAAGA
GAAAGAAGCACTCTTCAAATCAGGTGCGATTCCGGTCGATCATTTAATTGCCCCAGAAGAACTCGTCACTAGCTACATCG
AGCGTCTGATTCAATATCCAGGTGCATTGCAGGTTGTGAGCTTTGCTGAACAGAAGGTTAGCCTAGTAGCAGTAAAAGCT
TATTACGGTGGACCATTGGTTGGTAATGCACTTTCTGCTTTGCGTGAGCACATGCCGCACATTGATACTCGTGTTGCCGC
TATCTTCCGTCAAGGTCGCCCTATTCGCCCACAAGGTACTACCATCATTGAAGCCGATGATGAAGTGTTCTTCGTCGCAG
CGAGTAACCATATCCGCTCAGTAATGAGTGAACTGCAACGCCTAGAGAAGCCGTACCGCCGCATCATGATTGTTGGCGGT
GGTAACATTGGTGCAAGTTTGGCAAAACGCCTTGAGCAAAGCTATAGCATCAAGCTTATCGAGCGCAGCTACACTCGCGC
CGAGAAGCTATCTGAAGAATTAGAAAACACCATCGTCTTCTGTGGTGATGCAGCAGACCAAGAACTGCTGACCGAAGAGA
ACATCGATCAAGTTGATGTGTTCATCGCTCTAACTAATGAAGATGAAACCAACATCATGTCAGCGATGCTGGCGAAGCGA
ATGGGCGCCAAGAAAGTAATGGTGCTGATTCAGCGTGGCGCTTATGTCGACCTTGTTCAGGGTGGCGTGATTGATATTGC
GATATCTCCACAGCAAGCGACGATTTCTGCGCTACTTACTCACGTTCGTCGTGCTGATATTGTTAACGTATCCTCTCTAC
GTCGCGGCGCTGCAGAAGCGATTGAAGCCATTGCTCACGGTGACGAAACTACCTCTAAGGTTGTTGGCCGAGCGATTGGC
GACATCAAACTGCCACCGGGCACCACCATTGGTGCGATTGTTCGCGGAGAAGAGGTGCTTATCGCGCACGATAGAACCGT
AATCGAACAGGATGACCACGTAGTGATGTTCCTAGTGGACAAGAAATACGTACCTGATGTTGAGTCTCTATTCCAACCGA
GCCCGTTCTTCTTATAG

Upstream 100 bases:

>100_bases
CGGCTAAGAATTTATTTCTTAGCCGCTGTTTCTTTCTAGTGCATTATCAAAGCGAAAAGAGATCACTAGAATTACAACGG
CAAAAAATAAGAGAAAGGCT

Downstream 100 bases:

>100_bases
CCTTGTTCTCGTAAGCTTCTTCTCGCAGCTTTCTTCTTGTGAGAACGACGCTCCGGCTCAAAGCGATGGTCAATTAAGCT
ATGGTCAACTTTCGTCCGAT

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKIIILGAGQVGGTLAENLVGENNDITIVDRNADRLRELQDKYDLRVVNGYASHPNTLREAGAQDADMLVAVTNMDETNM
AACQVAFSLFNTPNRIARIRSPQYLEEKEALFKSGAIPVDHLIAPEELVTSYIERLIQYPGALQVVSFAEQKVSLVAVKA
YYGGPLVGNALSALREHMPHIDTRVAAIFRQGRPIRPQGTTIIEADDEVFFVAASNHIRSVMSELQRLEKPYRRIMIVGG
GNIGASLAKRLEQSYSIKLIERSYTRAEKLSEELENTIVFCGDAADQELLTEENIDQVDVFIALTNEDETNIMSAMLAKR
MGAKKVMVLIQRGAYVDLVQGGVIDIAISPQQATISALLTHVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGRAIG
DIKLPPGTTIGAIVRGEEVLIAHDRTVIEQDDHVVMFLVDKKYVPDVESLFQPSPFFL

Sequences:

>Translated_458_residues
MKIIILGAGQVGGTLAENLVGENNDITIVDRNADRLRELQDKYDLRVVNGYASHPNTLREAGAQDADMLVAVTNMDETNM
AACQVAFSLFNTPNRIARIRSPQYLEEKEALFKSGAIPVDHLIAPEELVTSYIERLIQYPGALQVVSFAEQKVSLVAVKA
YYGGPLVGNALSALREHMPHIDTRVAAIFRQGRPIRPQGTTIIEADDEVFFVAASNHIRSVMSELQRLEKPYRRIMIVGG
GNIGASLAKRLEQSYSIKLIERSYTRAEKLSEELENTIVFCGDAADQELLTEENIDQVDVFIALTNEDETNIMSAMLAKR
MGAKKVMVLIQRGAYVDLVQGGVIDIAISPQQATISALLTHVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGRAIG
DIKLPPGTTIGAIVRGEEVLIAHDRTVIEQDDHVVMFLVDKKYVPDVESLFQPSPFFL
>Mature_458_residues
MKIIILGAGQVGGTLAENLVGENNDITIVDRNADRLRELQDKYDLRVVNGYASHPNTLREAGAQDADMLVAVTNMDETNM
AACQVAFSLFNTPNRIARIRSPQYLEEKEALFKSGAIPVDHLIAPEELVTSYIERLIQYPGALQVVSFAEQKVSLVAVKA
YYGGPLVGNALSALREHMPHIDTRVAAIFRQGRPIRPQGTTIIEADDEVFFVAASNHIRSVMSELQRLEKPYRRIMIVGG
GNIGASLAKRLEQSYSIKLIERSYTRAEKLSEELENTIVFCGDAADQELLTEENIDQVDVFIALTNEDETNIMSAMLAKR
MGAKKVMVLIQRGAYVDLVQGGVIDIAISPQQATISALLTHVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGRAIG
DIKLPPGTTIGAIVRGEEVLIAHDRTVIEQDDHVVMFLVDKKYVPDVESLFQPSPFFL

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=78.3842794759825, Blast_Score=747, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50317; Mature: 50317

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITIVDRNADRLRELQDKYDLRVVNGYASHPNTLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCEEEEECCCCCCHHHHH
AGAQDADMLVAVTNMDETNMAACQVAFSLFNTPNRIARIRSPQYLEEKEALFKSGAIPVD
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCCCHH
HLIAPEELVTSYIERLIQYPGALQVVSFAEQKVSLVAVKAYYGGPLVGNALSALREHMPH
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHCCC
IDTRVAAIFRQGRPIRPQGTTIIEADDEVFFVAASNHIRSVMSELQRLEKPYRRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEC
GNIGASLAKRLEQSYSIKLIERSYTRAEKLSEELENTIVFCGDAADQELLTEENIDQVDV
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHCCCCEEEE
FIALTNEDETNIMSAMLAKRMGAKKVMVLIQRGAYVDLVQGGVIDIAISPQQATISALLT
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHH
HVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGRAIGDIKLPPGTTIGAIVRGEEVL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEE
IAHDRTVIEQDDHVVMFLVDKKYVPDVESLFQPSPFFL
EEECCEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure
MKIIILGAGQVGGTLAENLVGENNDITIVDRNADRLRELQDKYDLRVVNGYASHPNTLRE
CEEEEEECCCCCHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCEEEEECCCCCCHHHHH
AGAQDADMLVAVTNMDETNMAACQVAFSLFNTPNRIARIRSPQYLEEKEALFKSGAIPVD
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCCCCCHH
HLIAPEELVTSYIERLIQYPGALQVVSFAEQKVSLVAVKAYYGGPLVGNALSALREHMPH
HCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHHHHCCC
IDTRVAAIFRQGRPIRPQGTTIIEADDEVFFVAASNHIRSVMSELQRLEKPYRRIMIVGG
HHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHEEEEEEC
GNIGASLAKRLEQSYSIKLIERSYTRAEKLSEELENTIVFCGDAADQELLTEENIDQVDV
CCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHCCCCEEEE
FIALTNEDETNIMSAMLAKRMGAKKVMVLIQRGAYVDLVQGGVIDIAISPQQATISALLT
EEEEECCCHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEECCCEEEEEECCCHHHHHHHHH
HVRRADIVNVSSLRRGAAEAIEAIAHGDETTSKVVGRAIGDIKLPPGTTIGAIVRGEEVL
HHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEE
IAHDRTVIEQDDHVVMFLVDKKYVPDVESLFQPSPFFL
EEECCEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7948029; 9720051 [H]