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The map label for this gene is prmA

Identifier: 218710862

GI number: 218710862

Start: 3105219

End: 3106106

Strand: Direct

Name: prmA

Synonym: VS_2946

Alternate gene names: 218710862

Gene position: 3105219-3106106 (Clockwise)

Preceding gene: 218710861

Following gene: 218710863

Centisome position: 94.12

GC content: 47.64

Gene sequence:

>888_bases
ATGCCTTGGATTCAAATCAAGCTTAATGCTACCAATGAAAATGCCGAACAAATCGGCGACATGTTAATGGAAGAGACTGG
TGCTCTTTCTGTAACTTTCCTGGATGCACAAGATACCCCTGTATTTGAGCCTCTGCCGGGCGAAACTCGCCTTTGGGGTG
ATACTGACATTCTCGCGCTTTACGACGCTGAGACTGACACTGGTGTCGTTCTAGCGCAGATTAAAGCAAGCAACATGTTC
CCTGCAGACTTTGCTCACAAAGTAGAGCAAATTGAAGACAAGGATTGGGAACGTGAATGGATGGACAACTTCCACCCAAT
GAAGTTTGGTGAGCGTTTATGGATCTGCCCTAGCTGGCGCGATATCCCTGAACCTGACGCTGTAAACGTAATGCTGGATC
CCGGTCTTGCATTCGGTACCGGTACTCACCCAACAACAGCATTGTGTCTTGAGTGGCTTGAAGGCCTAGACCTGACAGGT
AAAACCGTGATCGATTTCGGTTGTGGTTCTGGCATTCTTGCGATCGCTGCGATCAAACTTGGCGCGGCAAAAGTTGTCGG
GATCGACATTGATCCTCAAGCTCTGCTTGCATCAAAAGACAATGCACAACGCAATGGTGTTGCTGAGCAACTAGAGGTGT
TCTTGCCACAAGATCAACCGGAAGGTTTGCTCGCTGACGTTGTTGTTGCCAACATTCTTGCCGGTCCATTACGCGACCTT
TCTGGCATCATTAAAGGTCTAGTAAAGCCAAATGGTGTACTAGCAATGTCGGGTGTTTTAGATACACAAGCGGAAGATGT
TGCAACTTATTATCGTGATGAGCTTCACATTGATCCGATCATTGAACAACAAGAATGGTGTCGAATCTCTGGTCGCAAGC
AAGGCTAG

Upstream 100 bases:

>100_bases
CAATTCATCATCCCCATTATATTCCGTGGGGTTTTGGTGAATTTGCTCATATTTTCTGCTAGACTCGCCATCCAATTTTT
CTCATATAGAAGATGCAGCC

Downstream 100 bases:

>100_bases
GTAAGACTTTGGGCGCTAATTGATTGAAATTTAAACGAATTACAAAAACAAATTGTAAATGCTCAAATATTAGTCTTTTC
ACGCAGCGAAAAAATGCGTA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILALYDAETDTGVVLAQIKASNMF
PADFAHKVEQIEDKDWEREWMDNFHPMKFGERLWICPSWRDIPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLEGLDLTG
KTVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQALLASKDNAQRNGVAEQLEVFLPQDQPEGLLADVVVANILAGPLRDL
SGIIKGLVKPNGVLAMSGVLDTQAEDVATYYRDELHIDPIIEQQEWCRISGRKQG

Sequences:

>Translated_295_residues
MPWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILALYDAETDTGVVLAQIKASNMF
PADFAHKVEQIEDKDWEREWMDNFHPMKFGERLWICPSWRDIPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLEGLDLTG
KTVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQALLASKDNAQRNGVAEQLEVFLPQDQPEGLLADVVVANILAGPLRDL
SGIIKGLVKPNGVLAMSGVLDTQAEDVATYYRDELHIDPIIEQQEWCRISGRKQG
>Mature_294_residues
PWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILALYDAETDTGVVLAQIKASNMFP
ADFAHKVEQIEDKDWEREWMDNFHPMKFGERLWICPSWRDIPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLEGLDLTGK
TVIDFGCGSGILAIAAIKLGAAKVVGIDIDPQALLASKDNAQRNGVAEQLEVFLPQDQPEGLLADVVVANILAGPLRDLS
GIIKGLVKPNGVLAMSGVLDTQAEDVATYYRDELHIDPIIEQQEWCRISGRKQG

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=294, Percent_Identity=69.0476190476191, Blast_Score=403, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_VIBSL (B7VM52)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418483.1
- ProteinModelPortal:   B7VM52
- GeneID:   7162429
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2946
- HOGENOM:   HBG584653
- OMA:   EDQDWER
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32307; Mature: 32176

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILAL
CCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YDAETDTGVVLAQIKASNMFPADFAHKVEQIEDKDWEREWMDNFHPMKFGERLWICPSWR
EECCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCC
DIPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLEGLDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVVGIDIDPQALLASKDNAQRNGVAEQLEVFLPQDQPEGLLADVVVANILAGPLRDL
CCEEEEEECCCCHHHEECCCCCHHCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
SGIIKGLVKPNGVLAMSGVLDTQAEDVATYYRDELHIDPIIEQQEWCRISGRKQG
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
PWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILAL
CEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEECCCCCEEEE
YDAETDTGVVLAQIKASNMFPADFAHKVEQIEDKDWEREWMDNFHPMKFGERLWICPSWR
EECCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEECCCCC
DIPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLEGLDLTGKTVIDFGCGSGILAIAAIKL
CCCCCCCEEEEECCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHH
GAAKVVGIDIDPQALLASKDNAQRNGVAEQLEVFLPQDQPEGLLADVVVANILAGPLRDL
CCEEEEEECCCCHHHEECCCCCHHCCHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHH
SGIIKGLVKPNGVLAMSGVLDTQAEDVATYYRDELHIDPIIEQQEWCRISGRKQG
HHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA