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The map label for this gene is rraA [H]

Identifier: 218710821

GI number: 218710821

Start: 3058853

End: 3059371

Strand: Direct

Name: rraA [H]

Synonym: VS_2904

Alternate gene names: 218710821

Gene position: 3058853-3059371 (Clockwise)

Preceding gene: 218710820

Following gene: 218710823

Centisome position: 92.71

GC content: 46.82

Gene sequence:

>519_bases
ATGGAATACAACACTTCAGCACTGTGCGACATATATTTGGATCAAGTTGATGTCGTGGAGCCAATGTTCAGCAACTTCGG
TGGACGTGCATCCTTCGCAGGACAGATCACGACATTAAAGTGTTTTGAAGACAATGCTTTAATTCGCTCCGTATTAGAAC
AAGATGGTTTGGGGCGTGTGTTGTTAATCGATGGTGGCGGCTCACTGCGTAAAGCGCTGATCGATGCTGAGATTGCCCTA
CTTGCTGAAGACAATGAGTGGGAAGGTATTGTGGTTTACGGCTGCGTACGCGAAGTCGATGAGTTAGAAGACATGAATCT
TGGTATTCAGGCTTTAGCCTCTATTCCTGTGGGTGCAAGCCAAGAAGGTGTCGGCGAATTGGATGTACCTGTGAACTTTG
GCAGCGTGACCTTCTTACCGGAAGATTACCTCTATGCAGACAACACTGGCATTATTCTTTCGGCAGAGCCTTTGGATGTA
GAACTCGATCTGGATGTTGAAGAAGAAGAGGCCGAGTAA

Upstream 100 bases:

>100_bases
GTCGTAGCTCAAACTCTATTGAGTTAAATGAGACTAATCATTGCAAAGGGATCAAGCACCGATATACTCAAAGTAAGCTC
ATTGTTCAAAAGGTATACTA

Downstream 100 bases:

>100_bases
CTCACTCAGCTTCAAATAATAAAACAAGCCAAAGAACACAAAGCATAAGAATACAAACGAAAACGCCCGCTACTGAGTAG
CGGGCGTTTTTTTAAATCTG

Product: ribonuclease activity regulator protein RraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MEYNTSALCDIYLDQVDVVEPMFSNFGGRASFAGQITTLKCFEDNALIRSVLEQDGLGRVLLIDGGGSLRKALIDAEIAL
LAEDNEWEGIVVYGCVREVDELEDMNLGIQALASIPVGASQEGVGELDVPVNFGSVTFLPEDYLYADNTGIILSAEPLDV
ELDLDVEEEEAE

Sequences:

>Translated_172_residues
MEYNTSALCDIYLDQVDVVEPMFSNFGGRASFAGQITTLKCFEDNALIRSVLEQDGLGRVLLIDGGGSLRKALIDAEIAL
LAEDNEWEGIVVYGCVREVDELEDMNLGIQALASIPVGASQEGVGELDVPVNFGSVTFLPEDYLYADNTGIILSAEPLDV
ELDLDVEEEEAE
>Mature_172_residues
MEYNTSALCDIYLDQVDVVEPMFSNFGGRASFAGQITTLKCFEDNALIRSVLEQDGLGRVLLIDGGGSLRKALIDAEIAL
LAEDNEWEGIVVYGCVREVDELEDMNLGIQALASIPVGASQEGVGELDVPVNFGSVTFLPEDYLYADNTGIILSAEPLDV
ELDLDVEEEEAE

Specific function: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RraA family [H]

Homologues:

Organism=Escherichia coli, GI1790364, Length=161, Percent_Identity=68.3229813664596, Blast_Score=236, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005493
- InterPro:   IPR014339
- InterPro:   IPR010203 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: NA

Molecular weight: Translated: 18639; Mature: 18639

Theoretical pI: Translated: 3.42; Mature: 3.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYNTSALCDIYLDQVDVVEPMFSNFGGRASFAGQITTLKCFEDNALIRSVLEQDGLGRV
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHCCCCEE
LLIDGGGSLRKALIDAEIALLAEDNEWEGIVVYGCVREVDELEDMNLGIQALASIPVGAS
EEEECCCHHHHHHHCEEEEEEEECCCCCEEEEEEEHHHHHHHHCCCCCHHHHCCCCCCCC
QEGVGELDVPVNFGSVTFLPEDYLYADNTGIILSAEPLDVELDLDVEEEEAE
CCCCCEEECEEECCEEEECCCCCEEECCCCEEEECCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MEYNTSALCDIYLDQVDVVEPMFSNFGGRASFAGQITTLKCFEDNALIRSVLEQDGLGRV
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHCCCCEE
LLIDGGGSLRKALIDAEIALLAEDNEWEGIVVYGCVREVDELEDMNLGIQALASIPVGAS
EEEECCCHHHHHHHCEEEEEEEECCCCCEEEEEEEHHHHHHHHCCCCCHHHHCCCCCCCC
QEGVGELDVPVNFGSVTFLPEDYLYADNTGIILSAEPLDVELDLDVEEEEAE
CCCCCEEECEEECCEEEECCCCCEEECCCCEEEECCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]