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The map label for this gene is oxyR [H]

Identifier: 218710796

GI number: 218710796

Start: 3028202

End: 3029095

Strand: Reverse

Name: oxyR [H]

Synonym: VS_2879

Alternate gene names: 218710796

Gene position: 3029095-3028202 (Counterclockwise)

Preceding gene: 218710799

Following gene: 218710794

Centisome position: 91.81

GC content: 47.65

Gene sequence:

>894_bases
ATGAACATTCGTGACTTTGAATACTTGGTGGCGCTCGCAGAGCACAAACACTTCCGAAAAGCGGCAGAAGCGTGCTTTGT
CAGTCAGCCGACACTAAGCGGTCAAATACGCAAACTAGAAGATGAAATTGGACTTCAGTTAACCGAGCGCAGTCCAAGGA
AGGTCATATTTACAGAATCAGGGTTACAACTTGTTGAACAAGCCAAGCGTATTCTCAATGAAGTAAAGACTTTTAAGGAT
ATGGCAAGTGGACACGGTGAAGCGATGACAGGGCCGATGCACATTGGTTTTATTCCGACCGTTGGCCCTTATATTTTACC
TAAGATCATTCCTCACCTTAAAGAGTGCTTTCCCGATCTTGAGCTTTACCTGCATGAAGCGCAGACCCATCAGCTAGTGA
GTCAACTTGAAGATGGCAAGCTTGATTGCTTGGTATTGGCTGCAGTTGATGAAACGGCGGCGTTCAAAGAGATTGATGTG
TATAACGAACCGTTAAGCGTCGCAGTGCCATGTGATCATGAGTGGGCTAAGCAAGACACGGTCGATATGTTGCAGTTAAA
TGGACAAACCGTACTTGCACTGGGCGATGGTCACTGCTTACGAGACCAAGCCTTGGGTTTCTGTTTTGCTGCGGGTGCAA
AAGACGATGAACGCTTTAAAGCGACCAGCTTAGAAACGCTGCGTAACATGGTAGCAGCAGGGGCGGGCATTACCTTGCTT
CCTCAGCTATCGGTACCGAAGGAAAAACAGAAAGATGGTGTGTGTTACGTGCCAGCGGTGAATCCAACACCTTCACGTCG
CATTGTTGTTGCCTACCGACCGGGCTCTCCGCTAAAGGGGCGTTTTGAGCAACTGGCTGAGTCTATCCGAATTCAATTAG
ATAAAGCTGTTTAG

Upstream 100 bases:

>100_bases
TGTTATGGTTTTGATAGGTAAATTCTATCAAGAGCATTTTTCTTTTAAATGTTTCTATGAAACCCCTTGTTCTTATTAAA
CCAGAGGTAAGAGACTGATC

Downstream 100 bases:

>100_bases
TCATTTAATTTAAATCGTAGATAGATCAGGTTAGAGACATAAAAAAAGGGTTGATATGAATTCATATCAACCCTTTTTGT
TGGTTCATGTTACTTGGTTC

Product: DNA-binding transcriptional regulator OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNIRDFEYLVALAEHKHFRKAAEACFVSQPTLSGQIRKLEDEIGLQLTERSPRKVIFTESGLQLVEQAKRILNEVKTFKD
MASGHGEAMTGPMHIGFIPTVGPYILPKIIPHLKECFPDLELYLHEAQTHQLVSQLEDGKLDCLVLAAVDETAAFKEIDV
YNEPLSVAVPCDHEWAKQDTVDMLQLNGQTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
PQLSVPKEKQKDGVCYVPAVNPTPSRRIVVAYRPGSPLKGRFEQLAESIRIQLDKAV

Sequences:

>Translated_297_residues
MNIRDFEYLVALAEHKHFRKAAEACFVSQPTLSGQIRKLEDEIGLQLTERSPRKVIFTESGLQLVEQAKRILNEVKTFKD
MASGHGEAMTGPMHIGFIPTVGPYILPKIIPHLKECFPDLELYLHEAQTHQLVSQLEDGKLDCLVLAAVDETAAFKEIDV
YNEPLSVAVPCDHEWAKQDTVDMLQLNGQTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
PQLSVPKEKQKDGVCYVPAVNPTPSRRIVVAYRPGSPLKGRFEQLAESIRIQLDKAV
>Mature_297_residues
MNIRDFEYLVALAEHKHFRKAAEACFVSQPTLSGQIRKLEDEIGLQLTERSPRKVIFTESGLQLVEQAKRILNEVKTFKD
MASGHGEAMTGPMHIGFIPTVGPYILPKIIPHLKECFPDLELYLHEAQTHQLVSQLEDGKLDCLVLAAVDETAAFKEIDV
YNEPLSVAVPCDHEWAKQDTVDMLQLNGQTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
PQLSVPKEKQKDGVCYVPAVNPTPSRRIVVAYRPGSPLKGRFEQLAESIRIQLDKAV

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=63.6054421768708, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1788887, Length=277, Percent_Identity=27.4368231046931, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI157672245, Length=276, Percent_Identity=27.1739130434783, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787879, Length=272, Percent_Identity=28.6764705882353, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI145693105, Length=284, Percent_Identity=26.7605633802817, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=24, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788748, Length=300, Percent_Identity=24.3333333333333, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=27.2357723577236, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367136, Length=277, Percent_Identity=24.187725631769, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=27.8884462151394, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=24.7967479674797, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788626, Length=271, Percent_Identity=25.830258302583, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789506, Length=146, Percent_Identity=28.7671232876712, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787806, Length=242, Percent_Identity=21.4876033057851, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=145, Percent_Identity=24.1379310344828, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32887; Mature: 32887

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRDFEYLVALAEHKHFRKAAEACFVSQPTLSGQIRKLEDEIGLQLTERSPRKVIFTES
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEECCCCCEEEEECH
GLQLVEQAKRILNEVKTFKDMASGHGEAMTGPMHIGFIPTVGPYILPKIIPHLKECFPDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCCCHHHHHHHHHHHHHHCCHH
ELYLHEAQTHQLVSQLEDGKLDCLVLAAVDETAAFKEIDVYNEPLSVAVPCDHEWAKQDT
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCHHHHCH
VDMLQLNGQTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
HHHHEECCCEEEEECCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
PQLSVPKEKQKDGVCYVPAVNPTPSRRIVVAYRPGSPLKGRFEQLAESIRIQLDKAV
ECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIRDFEYLVALAEHKHFRKAAEACFVSQPTLSGQIRKLEDEIGLQLTERSPRKVIFTES
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCEEEECCCCCEEEEECH
GLQLVEQAKRILNEVKTFKDMASGHGEAMTGPMHIGFIPTVGPYILPKIIPHLKECFPDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEECCCCCHHHHHHHHHHHHHHCCHH
ELYLHEAQTHQLVSQLEDGKLDCLVLAAVDETAAFKEIDVYNEPLSVAVPCDHEWAKQDT
HHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCHHHHCH
VDMLQLNGQTVLALGDGHCLRDQALGFCFAAGAKDDERFKATSLETLRNMVAAGAGITLL
HHHHEECCCEEEEECCCCCHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
PQLSVPKEKQKDGVCYVPAVNPTPSRRIVVAYRPGSPLKGRFEQLAESIRIQLDKAV
ECCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA