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The map label for this gene is argD [H]

Identifier: 218710778

GI number: 218710778

Start: 3005407

End: 3006618

Strand: Reverse

Name: argD [H]

Synonym: VS_2861

Alternate gene names: 218710778

Gene position: 3006618-3005407 (Counterclockwise)

Preceding gene: 218710779

Following gene: 218710777

Centisome position: 91.13

GC content: 47.77

Gene sequence:

>1212_bases
ATGACAGTGGAAAAAAAAGTAGAACGTAGTCTGTTTAATGAGGTGATGGTGCCTTGTTATAACCCAATGGAAATGATCCC
GGTAAAAGGGGAAGGCGCACGCGTTTGGGACCAACAAGGCCGAGAGTATATCGACTTTGCTGGTGGTATCGCTGTGAGCT
GTTTGGGTCACTGTCACCCAGCAATGGTTAACGCAGTTACTGAGCAAGCAAACAAGATTTGGCATTTAAGTAACGTAATG
ACCAACGAACCTGCACTACGTCTAGCGAAGAAGTTAACAGACGTATGTTTTGCAGAAAAAGTATTCTTTGCCAACTCTGG
TGCTGAAGCGAACGAAGCCGCATTGAAGCTAGCTCGTCGTTGGGCAGCGGATGTTCACGGTCCTGAGAAATCTGAAATCA
TTGCATTCAAACAAGGTTTCCACGGTCGTACTTTCTTTACTGTAACTGTGGGGGGGCAAGAGGCTTACTCTGATGGCTTC
GGTCCTAAACCGGGCGATGTAACTCACCTGCCTTACAACGATATTGCAGCGCTAGAAGCGCACATCTCAGATCGCACATG
TGCAATCATGATGGAACCTCTACAAGGCGAGGGCGGTATCATCTCTCCAACATCTGAGTTCGTGAACACGGTTCGTGAAC
TGTGTGACAAACACAATGCGCTGCTTATCTTTGATGAAGTGCAAACGGGTAATGGCCGCACGGGTAACTTTTACGCTTAC
CAAGGCCTAGGTGTAACACCTGATATCCTAAGCACTGCGAAATCACTAGGTGGTGGTTTCCCAATCGGCGCAATGCTAAC
AACGTCTGAACTTGCAACACACCTAAAAGTGGGTACGCACGGTTCTACTTACGGCGGCAACCCACTGGCGTGTGCCGTTG
CTGAAGCGGTTGTTGATGTAGTAAGCCAACCTGAAACGTTGGCTGGCGTGAAAGAACGTGAAGCACTATTCCGTGATGGT
TTAGCTAAGATTAACGACAAATACCAAATATTCAGTGAAGTTCGCGGTAAAGGCCTATTGCTAGGCGCGGCGCTTAATGA
AGCATGGCAAGGTCGTGCTCGTGATGTATTAGTGGCAGCAGGCGAACAAGGCTTGATGGTACTGGTTGCGGGTGCAAACG
TGGTTCGTTTCACACCATCACTGGTTATCACTACACAAGAAATTGAAGAAGGTTTATCAAAACTAGACAAAGCCATCGCT
ACGCTAGTTTAG

Upstream 100 bases:

>100_bases
TAATGCTGCAGCGGGATTATGGCGAGAGAAAATATCTTTGTCTCACTTATGAACCAGTACGCTTATTTGCGAAGCTTGCG
GTATCGAGAAGGAATGTACG

Downstream 100 bases:

>100_bases
CCTGAGCGGCGTCATAGGAATGATCGCCATTAGAGCGATCCCATGACGTACTGCTAAAGGCCCAAGATTCTCGTTTTGGG
CCTGTTTTGCATCTGGAGGG

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTVEKKVERSLFNEVMVPCYNPMEMIPVKGEGARVWDQQGREYIDFAGGIAVSCLGHCHPAMVNAVTEQANKIWHLSNVM
TNEPALRLAKKLTDVCFAEKVFFANSGAEANEAALKLARRWAADVHGPEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGF
GPKPGDVTHLPYNDIAALEAHISDRTCAIMMEPLQGEGGIISPTSEFVNTVRELCDKHNALLIFDEVQTGNGRTGNFYAY
QGLGVTPDILSTAKSLGGGFPIGAMLTTSELATHLKVGTHGSTYGGNPLACAVAEAVVDVVSQPETLAGVKEREALFRDG
LAKINDKYQIFSEVRGKGLLLGAALNEAWQGRARDVLVAAGEQGLMVLVAGANVVRFTPSLVITTQEIEEGLSKLDKAIA
TLV

Sequences:

>Translated_403_residues
MTVEKKVERSLFNEVMVPCYNPMEMIPVKGEGARVWDQQGREYIDFAGGIAVSCLGHCHPAMVNAVTEQANKIWHLSNVM
TNEPALRLAKKLTDVCFAEKVFFANSGAEANEAALKLARRWAADVHGPEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGF
GPKPGDVTHLPYNDIAALEAHISDRTCAIMMEPLQGEGGIISPTSEFVNTVRELCDKHNALLIFDEVQTGNGRTGNFYAY
QGLGVTPDILSTAKSLGGGFPIGAMLTTSELATHLKVGTHGSTYGGNPLACAVAEAVVDVVSQPETLAGVKEREALFRDG
LAKINDKYQIFSEVRGKGLLLGAALNEAWQGRARDVLVAAGEQGLMVLVAGANVVRFTPSLVITTQEIEEGLSKLDKAIA
TLV
>Mature_402_residues
TVEKKVERSLFNEVMVPCYNPMEMIPVKGEGARVWDQQGREYIDFAGGIAVSCLGHCHPAMVNAVTEQANKIWHLSNVMT
NEPALRLAKKLTDVCFAEKVFFANSGAEANEAALKLARRWAADVHGPEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGFG
PKPGDVTHLPYNDIAALEAHISDRTCAIMMEPLQGEGGIISPTSEFVNTVRELCDKHNALLIFDEVQTGNGRTGNFYAYQ
GLGVTPDILSTAKSLGGGFPIGAMLTTSELATHLKVGTHGSTYGGNPLACAVAEAVVDVVSQPETLAGVKEREALFRDGL
AKINDKYQIFSEVRGKGLLLGAALNEAWQGRARDVLVAAGEQGLMVLVAGANVVRFTPSLVITTQEIEEGLSKLDKAIAT
LV

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=387, Percent_Identity=35.9173126614987, Blast_Score=245, Evalue=5e-65,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=37.4172185430464, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI13994255, Length=423, Percent_Identity=29.5508274231678, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI37574042, Length=414, Percent_Identity=27.2946859903382, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI24119277, Length=414, Percent_Identity=26.3285024154589, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI226442709, Length=380, Percent_Identity=27.8947368421053, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=26.0869565217391, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI188536080, Length=415, Percent_Identity=21.4457831325301, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI38679950, Length=415, Percent_Identity=21.4457831325301, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI38679946, Length=415, Percent_Identity=21.4457831325301, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1789759, Length=404, Percent_Identity=57.6732673267327, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1788044, Length=401, Percent_Identity=56.857855361596, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=35.7682619647355, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI145693181, Length=385, Percent_Identity=35.0649350649351, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1787560, Length=397, Percent_Identity=34.2569269521411, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1786991, Length=406, Percent_Identity=28.3251231527094, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786349, Length=335, Percent_Identity=31.3432835820896, Blast_Score=128, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=36.5284974093264, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=30.9468822170901, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI25144274, Length=271, Percent_Identity=35.4243542435424, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=418, Percent_Identity=26.3157894736842, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=34.1772151898734, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=26.1958997722096, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=37.4045801526718, Blast_Score=263, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=35.1485148514851, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=346, Percent_Identity=28.9017341040462, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=435, Percent_Identity=24.367816091954, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21357415, Length=387, Percent_Identity=35.6589147286822, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI161085790, Length=425, Percent_Identity=30.3529411764706, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI28574759, Length=425, Percent_Identity=30.5882352941176, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21356575, Length=422, Percent_Identity=28.9099526066351, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=23.3796296296296, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=23.3796296296296, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=23.3796296296296, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43267; Mature: 43136

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEKKVERSLFNEVMVPCYNPMEMIPVKGEGARVWDQQGREYIDFAGGIAVSCLGHCHP
CCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHCCCHHHHHHHCCCH
AMVNAVTEQANKIWHLSNVMTNEPALRLAKKLTDVCFAEKVFFANSGAEANEAALKLARR
HHHHHHHHHHHHEEEHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
WAADVHGPEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGFGPKPGDVTHLPYNDIAALEA
HHHHCCCCCCCCEEEEECCCCCCEEEEEEECCHHHHCCCCCCCCCCEEECCCCHHHHHHH
HISDRTCAIMMEPLQGEGGIISPTSEFVNTVRELCDKHNALLIFDEVQTGNGRTGNFYAY
HCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEE
QGLGVTPDILSTAKSLGGGFPIGAMLTTSELATHLKVGTHGSTYGGNPLACAVAEAVVDV
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHH
VSQPETLAGVKEREALFRDGLAKINDKYQIFSEVRGKGLLLGAALNEAWQGRARDVLVAA
HCCCHHHHCCHHHHHHHHCCHHHHCHHHHHHHHHCCCEEEEEHHHHHHHCCCCCEEEEEE
GEQGLMVLVAGANVVRFTPSLVITTQEIEEGLSKLDKAIATLV
CCCCCEEEEECCCEEEECCCEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVEKKVERSLFNEVMVPCYNPMEMIPVKGEGARVWDQQGREYIDFAGGIAVSCLGHCHP
CCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHCCCHHHHHHHCCCH
AMVNAVTEQANKIWHLSNVMTNEPALRLAKKLTDVCFAEKVFFANSGAEANEAALKLARR
HHHHHHHHHHHHEEEHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHH
WAADVHGPEKSEIIAFKQGFHGRTFFTVTVGGQEAYSDGFGPKPGDVTHLPYNDIAALEA
HHHHCCCCCCCCEEEEECCCCCCEEEEEEECCHHHHCCCCCCCCCCEEECCCCHHHHHHH
HISDRTCAIMMEPLQGEGGIISPTSEFVNTVRELCDKHNALLIFDEVQTGNGRTGNFYAY
HCCCCEEEEEEECCCCCCCEECCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEE
QGLGVTPDILSTAKSLGGGFPIGAMLTTSELATHLKVGTHGSTYGGNPLACAVAEAVVDV
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHH
VSQPETLAGVKEREALFRDGLAKINDKYQIFSEVRGKGLLLGAALNEAWQGRARDVLVAA
HCCCHHHHCCHHHHHHHHCCHHHHCHHHHHHHHHCCCEEEEEHHHHHHHCCCCCEEEEEE
GEQGLMVLVAGANVVRFTPSLVITTQEIEEGLSKLDKAIATLV
CCCCCEEEEECCCEEEECCCEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]