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The map label for this gene is yheS [H]

Identifier: 218710767

GI number: 218710767

Start: 2994526

End: 2996448

Strand: Direct

Name: yheS [H]

Synonym: VS_2850

Alternate gene names: 218710767

Gene position: 2994526-2996448 (Clockwise)

Preceding gene: 218710761

Following gene: 218710768

Centisome position: 90.76

GC content: 46.33

Gene sequence:

>1923_bases
ATGATTACTTTCTCTGATATTCAATTGCTACGCGGCGGTAAGCCACTCCTCGACCAAGCATCTGCGACTTTTCACCCTGG
CGACAAGATCGGTTTGGTTGGTAAGAATGGCTGTGGTAAATCTACGCTGTTCGCCCTAATTAAGGACGAACTGTCTATTG
ATGCAGGCTCATTCAGTAAACCAGCCCATTGGGAAATGGCTTGGGTTGCTCAAGAAACACCTGCATTAGAAAGAACAGCA
ATTGAATACGTGATTGATGGCGACCGTGAATACCGTGGCCTTGAAGATCAACTTGAGAAAGCCGAACAAGCCGACAACGG
CACATTAGTCGCAGAGATCCATGGCAAGATTGAAACCATTGGTGGTTATAGCATCAAAGCACGCGCGGCTGAGCTGTTAG
ACGGCCTGGGCTTTCGCCAAGAACAAATGACATGGAACCTGACTCAATTTTCAGGGGGTTGGCGTATGCGTTTAAACCTA
GCGCAAGCCCTACTGTGTCGCAGTGACCTACTGTTACTCGATGAGCCAACCAACCACTTGGATTTAGACGCTGTAATGTG
GCTAGAACGCTGGTTACAAAACTACCCAGGCACACTGGTTCTTATCTCACACGATAGGGACTTCTTGGATCCTATCGTCA
ACCGCATCGTGCATGTTGAAAATCAACTGCTCAATGAATACACCGGTAACTACTCGTCGTTCGAAATCCAACGAGCGCAA
AAGCTAATTCTACAACAAGCGATGTACCAAAAGCAGCAGAAACAAATGTCGCACATGCAGAGCTACATTGACCGTTTCCG
TTACAAAGCTTCAAAAGCTCGCCAAGCGCAAAGCCGTATTAAAGCGCTAGAGAAAATGGAACAAGTACTGCCCGCTCAGT
TTGATAACCCTTTCAGCTTTGAATTTAGAGAACCAGACGCACTACCAAACCCAATCATGATGATGGACGAGGTCTCTGCA
GGTTACGATGACAATCTGATTCTAGAGAAGATTCGCCTAAACCTAGTACCGGGCAGCCGTATTGGTTTACTTGGTCGAAA
TGGTGCAGGTAAATCGACGCTGATTAAGCTGCTTTCAGGTGAACTGAAACAACAAGGTGGCGAGCTAAGCTATTCGCAAG
GCGTTAAAATGGGTTACTTTGCCCAACACCAATTAGAGACGCTGCACCCGGAAGAGACACCACTTCAGCACATGATGCAG
ATTGCGCCAAAACACACCGAGCAACAACTGCGTGACTACCTAGGTAGCTTTGGCTTCCAAGGTGAAAAAGCACTCGATAA
AGTGGCACCGTTCTCCGGTGGTGAAAAAGCGCGTTTGGTATTGGCTCTGCTGGTATGGCAAAAACCGAACCTATTACTAC
TCGATGAACCAACCAACCACTTGGATCTCGATATGCGTCAGGCACTAACGTTTGCATTGCAGACGTTTGAAGGCGCGATG
GTTATCGTATCGCACGACCGCTACCTACTTCGTGCCACTACTGATGATTTATACCTTGTACACGACCGTCAAGTTGCACC
GTTTGATGGTGACCTTAGCGATTACTACAAGTGGCTAACCGAACAACAGAAAGTTGAGCGAAAAGAAGCACAAGCATTGG
CACCAGCAAAAGATGGCGCCAACAGTGCAGCAGCAAAAAAAGATCAGAAACGTAAAGAAGCAGAGTTCCGGAAACTAACG
GCACCAATTCGTAAAAAGCTGACTCAATTTGAAAAGCAGATGGATAAATTAACGTTAGCTCTTGAAGAAGCCGAGCAAGA
ATTATCCGATACTTCACTGTATGAAGCTGAAAATAAGGCTAAACTGAATAAAGTACTCGCTCTACAAGCGAGCAGTAAGT
CACAGCTAGAAGAAGTTGAAATGGATTGGATGTCCACTCAAGAAGAGCTTGAGCAGATGGAACTGGATATGGATAGCTTA
TGA

Upstream 100 bases:

>100_bases
ATTGGCATCATAACGCAAATTGCATTGTGATCGACTTTTATCTGGTTTCAGCCTACTATGCAGGCGTCTGTTCACCTCTA
ATTTCTATGCTATTTCAATT

Downstream 100 bases:

>100_bases
GCCCAGAGCACGCACCAATATCACTAACACTGGAACGACTATGGCAATTTAGCCTTCAATATTACAGTGTGCGCGGTGTT
AAGGATGCGTGCTTAGCTTT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MITFSDIQLLRGGKPLLDQASATFHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSKPAHWEMAWVAQETPALERTA
IEYVIDGDREYRGLEDQLEKAEQADNGTLVAEIHGKIETIGGYSIKARAAELLDGLGFRQEQMTWNLTQFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVMWLERWLQNYPGTLVLISHDRDFLDPIVNRIVHVENQLLNEYTGNYSSFEIQRAQ
KLILQQAMYQKQQKQMSHMQSYIDRFRYKASKARQAQSRIKALEKMEQVLPAQFDNPFSFEFREPDALPNPIMMMDEVSA
GYDDNLILEKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELKQQGGELSYSQGVKMGYFAQHQLETLHPEETPLQHMMQ
IAPKHTEQQLRDYLGSFGFQGEKALDKVAPFSGGEKARLVLALLVWQKPNLLLLDEPTNHLDLDMRQALTFALQTFEGAM
VIVSHDRYLLRATTDDLYLVHDRQVAPFDGDLSDYYKWLTEQQKVERKEAQALAPAKDGANSAAAKKDQKRKEAEFRKLT
APIRKKLTQFEKQMDKLTLALEEAEQELSDTSLYEAENKAKLNKVLALQASSKSQLEEVEMDWMSTQEELEQMELDMDSL

Sequences:

>Translated_640_residues
MITFSDIQLLRGGKPLLDQASATFHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSKPAHWEMAWVAQETPALERTA
IEYVIDGDREYRGLEDQLEKAEQADNGTLVAEIHGKIETIGGYSIKARAAELLDGLGFRQEQMTWNLTQFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVMWLERWLQNYPGTLVLISHDRDFLDPIVNRIVHVENQLLNEYTGNYSSFEIQRAQ
KLILQQAMYQKQQKQMSHMQSYIDRFRYKASKARQAQSRIKALEKMEQVLPAQFDNPFSFEFREPDALPNPIMMMDEVSA
GYDDNLILEKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELKQQGGELSYSQGVKMGYFAQHQLETLHPEETPLQHMMQ
IAPKHTEQQLRDYLGSFGFQGEKALDKVAPFSGGEKARLVLALLVWQKPNLLLLDEPTNHLDLDMRQALTFALQTFEGAM
VIVSHDRYLLRATTDDLYLVHDRQVAPFDGDLSDYYKWLTEQQKVERKEAQALAPAKDGANSAAAKKDQKRKEAEFRKLT
APIRKKLTQFEKQMDKLTLALEEAEQELSDTSLYEAENKAKLNKVLALQASSKSQLEEVEMDWMSTQEELEQMELDMDSL
>Mature_640_residues
MITFSDIQLLRGGKPLLDQASATFHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSKPAHWEMAWVAQETPALERTA
IEYVIDGDREYRGLEDQLEKAEQADNGTLVAEIHGKIETIGGYSIKARAAELLDGLGFRQEQMTWNLTQFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVMWLERWLQNYPGTLVLISHDRDFLDPIVNRIVHVENQLLNEYTGNYSSFEIQRAQ
KLILQQAMYQKQQKQMSHMQSYIDRFRYKASKARQAQSRIKALEKMEQVLPAQFDNPFSFEFREPDALPNPIMMMDEVSA
GYDDNLILEKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSGELKQQGGELSYSQGVKMGYFAQHQLETLHPEETPLQHMMQ
IAPKHTEQQLRDYLGSFGFQGEKALDKVAPFSGGEKARLVLALLVWQKPNLLLLDEPTNHLDLDMRQALTFALQTFEGAM
VIVSHDRYLLRATTDDLYLVHDRQVAPFDGDLSDYYKWLTEQQKVERKEAQALAPAKDGANSAAAKKDQKRKEAEFRKLT
APIRKKLTQFEKQMDKLTLALEEAEQELSDTSLYEAENKAKLNKVLALQASSKSQLEEVEMDWMSTQEELEQMELDMDSL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=528, Percent_Identity=37.8787878787879, Blast_Score=354, Evalue=2e-97,
Organism=Homo sapiens, GI27881506, Length=530, Percent_Identity=36.6037735849057, Blast_Score=319, Evalue=5e-87,
Organism=Homo sapiens, GI10947137, Length=530, Percent_Identity=36.6037735849057, Blast_Score=319, Evalue=5e-87,
Organism=Homo sapiens, GI10947135, Length=540, Percent_Identity=34.6296296296296, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI69354671, Length=540, Percent_Identity=34.6296296296296, Blast_Score=257, Evalue=2e-68,
Organism=Escherichia coli, GI1789751, Length=639, Percent_Identity=64.3192488262911, Blast_Score=871, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=33.0812854442344, Blast_Score=301, Evalue=1e-82,
Organism=Escherichia coli, GI1787182, Length=640, Percent_Identity=27.1875, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI2367384, Length=544, Percent_Identity=31.4338235294118, Blast_Score=225, Evalue=8e-60,
Organism=Escherichia coli, GI1788165, Length=202, Percent_Identity=30.1980198019802, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1787758, Length=207, Percent_Identity=28.9855072463768, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789891, Length=210, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787164, Length=215, Percent_Identity=27.4418604651163, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788506, Length=209, Percent_Identity=25.3588516746411, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786563, Length=212, Percent_Identity=28.7735849056604, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=535, Percent_Identity=38.5046728971963, Blast_Score=357, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI17559834, Length=534, Percent_Identity=34.4569288389513, Blast_Score=315, Evalue=5e-86,
Organism=Caenorhabditis elegans, GI17555318, Length=521, Percent_Identity=35.1247600767754, Blast_Score=315, Evalue=6e-86,
Organism=Saccharomyces cerevisiae, GI6321121, Length=536, Percent_Identity=35.8208955223881, Blast_Score=338, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6320874, Length=526, Percent_Identity=35.5513307984791, Blast_Score=323, Evalue=7e-89,
Organism=Saccharomyces cerevisiae, GI6325030, Length=407, Percent_Identity=28.009828009828, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323278, Length=397, Percent_Identity=27.7078085642317, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6324314, Length=398, Percent_Identity=28.643216080402, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=37.9506641366224, Blast_Score=370, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=524, Percent_Identity=36.4503816793893, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI18859989, Length=524, Percent_Identity=36.4503816793893, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24641342, Length=537, Percent_Identity=34.6368715083799, Blast_Score=306, Evalue=3e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72702; Mature: 72702

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFSDIQLLRGGKPLLDQASATFHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSK
CCCHHHHHHHCCCCCHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PAHWEMAWVAQETPALERTAIEYVIDGDREYRGLEDQLEKAEQADNGTLVAEIHGKIETI
CCCCEEEEEECCCCCHHHHHHHHEECCCHHCCCHHHHHHHHHHCCCCCEEEEECCCEEEC
GGYSIKARAAELLDGLGFRQEQMTWNLTQFSGGWRMRLNLAQALLCRSDLLLLDEPTNHL
CCCCHHHHHHHHHHCCCCCCHHCEEEEEEECCCEEEHHHHHHHHHHHCCEEEEECCCCCC
DLDAVMWLERWLQNYPGTLVLISHDRDFLDPIVNRIVHVENQLLNEYTGNYSSFEIQRAQ
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KLILQQAMYQKQQKQMSHMQSYIDRFRYKASKARQAQSRIKALEKMEQVLPAQFDNPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EFREPDALPNPIMMMDEVSAGYDDNLILEKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSG
CCCCCCCCCCCEEEHHHHCCCCCCCCEEEEHEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELKQQGGELSYSQGVKMGYFAQHQLETLHPEETPLQHMMQIAPKHTEQQLRDYLGSFGFQ
HHHHCCCCCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCC
GEKALDKVAPFSGGEKARLVLALLVWQKPNLLLLDEPTNHLDLDMRQALTFALQTFEGAM
CHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRYLLRATTDDLYLVHDRQVAPFDGDLSDYYKWLTEQQKVERKEAQALAPAKDGA
EEEECCCEEEEECCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NSAAAKKDQKRKEAEFRKLTAPIRKKLTQFEKQMDKLTLALEEAEQELSDTSLYEAENKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLNKVLALQASSKSQLEEVEMDWMSTQEELEQMELDMDSL
HHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MITFSDIQLLRGGKPLLDQASATFHPGDKIGLVGKNGCGKSTLFALIKDELSIDAGSFSK
CCCHHHHHHHCCCCCHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PAHWEMAWVAQETPALERTAIEYVIDGDREYRGLEDQLEKAEQADNGTLVAEIHGKIETI
CCCCEEEEEECCCCCHHHHHHHHEECCCHHCCCHHHHHHHHHHCCCCCEEEEECCCEEEC
GGYSIKARAAELLDGLGFRQEQMTWNLTQFSGGWRMRLNLAQALLCRSDLLLLDEPTNHL
CCCCHHHHHHHHHHCCCCCCHHCEEEEEEECCCEEEHHHHHHHHHHHCCEEEEECCCCCC
DLDAVMWLERWLQNYPGTLVLISHDRDFLDPIVNRIVHVENQLLNEYTGNYSSFEIQRAQ
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KLILQQAMYQKQQKQMSHMQSYIDRFRYKASKARQAQSRIKALEKMEQVLPAQFDNPFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EFREPDALPNPIMMMDEVSAGYDDNLILEKIRLNLVPGSRIGLLGRNGAGKSTLIKLLSG
CCCCCCCCCCCEEEHHHHCCCCCCCCEEEEHEEEECCCCCEEEEECCCCCHHHHHHHHHH
ELKQQGGELSYSQGVKMGYFAQHQLETLHPEETPLQHMMQIAPKHTEQQLRDYLGSFGFQ
HHHHCCCCCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCC
GEKALDKVAPFSGGEKARLVLALLVWQKPNLLLLDEPTNHLDLDMRQALTFALQTFEGAM
CHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCEE
VIVSHDRYLLRATTDDLYLVHDRQVAPFDGDLSDYYKWLTEQQKVERKEAQALAPAKDGA
EEEECCCEEEEECCCCEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NSAAAKKDQKRKEAEFRKLTAPIRKKLTQFEKQMDKLTLALEEAEQELSDTSLYEAENKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLNKVLALQASSKSQLEEVEMDWMSTQEELEQMELDMDSL
HHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]