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The map label for this gene is secY [H]

Identifier: 218710729

GI number: 218710729

Start: 2969748

End: 2971082

Strand: Reverse

Name: secY [H]

Synonym: VS_2811

Alternate gene names: 218710729

Gene position: 2971082-2969748 (Counterclockwise)

Preceding gene: 218710730

Following gene: 218710728

Centisome position: 90.05

GC content: 43.37

Gene sequence:

>1335_bases
ATGGCTAAGAAACCAGGAAAAGATTTTCGTAGTGCTCAGAGCGGCTTAAGTGAACTAAAGTCGCGCTTATTATTCGTAAT
TGGTGCACTTTTAGTATTCCGAGCCGGCTCTTTTGTGCCGATCCCTGGTATTGACGCAGCTGTACTTGCCGATTTGTTCG
ATCAGCAAAAAGGTACCATCGTAGAAATGTTTAACATGTTCTCCGGTGGTGCTCTTGAGCGTGCATCTATATTAGCATTG
GGTATCATGCCGTACATTTCGGCATCGATCGTAGTCCAATTGCTAACTGTAGTTCATCCAGCGTTAGCGGAACTCAAAAA
AGAGGGTGAAGCAGGCCGTCGTAAGATAAGCCAATATACACGCTACGGCACGCTTGTACTTGCAACATTCCAAGCTATTG
GTATCGCAACAGGCTTACCAAACATGGTCGACAATCTGGTTGTTATCAACCAAACCATGTTTACGCTTATTGCTACCGTG
AGTTTAGTAACTGGTACCATGTTTTTGATGTGGTTAGGTGAACAAATCACTGAGCGAGGAATCGGTAATGGTATTTCCAT
TCTGATTTTTGCAGGTATTGTTGCTGGATTGCCTTCTGCAATCGGTCAAACAATCGAGCAAGCGCGTCAAGGTGAATTGC
ATGTGCTTCTTCTGTTGTTTATCGCGGTATTGTCTTTTGCTGTAATTTACTTCGTAGTTTTCATGGAACGTGGTCAACGT
CGTATCGTCGTTAACTATGCGAAGCGTCAACAAGGTCGTAAAGTTTTTGCAGCTCAAAGCTCTCACTTGCCTCTTAAGAT
TAATATGGCAGGTGTTATTCCAGCGATTTTTGCATCAAGTATTATTTTGTTCCCAGGAACATTAGCACAATGGTTTGGTC
AAAATGGTGAAAGCAGCGCGTTCGGTTGGTTAACTGACGTGTCATTAGCTCTTAGCCCTGGTCAACCTTTGTATGTAATG
CTTTATGCAGCAGCTATAATCTTCTTCTGTTTCTTCTATACAGCGTTGGTGTTTAACCCGCGTGAAACAGCTGATAATTT
GAAGAAGTCTGGTGCATTCGTACCCGGTATCCGCCCAGGTGAGCAGACAGCGAAATATATCGATAAAGTGATGACTAGGC
TAACCCTTGCGGGCGCTCTATACATTACTTTTATATGTCTGATTCCTGAATTCATGATGGTCGCGTGGAACGTTCGTTTC
TACTTCGGCGGCACATCACTACTAATCGTAGTGGTAGTTATCATGGATTTCATGGCACAGGTACAGACTCATCTGATGTC
ACAACAGTATGATTCTGTGTTAAAGAAAGCGAATCTGAAAGGTTACGGCCGTTAA

Upstream 100 bases:

>100_bases
CTGTGACTGTTAAAGGTCTACGCGTGACTAAAGGCGCTAAAGCTGCAATCGAAGCTGCAGGCGGTAAAATCGAGGAATAA
TCTCGAGGAACGAGGTACAG

Downstream 100 bases:

>100_bases
TTCGGTAGTAATTATTTCGATTCCATTTACGGAGTTTAGCAATGAAAGTTCGTGCTTCCGTTAAAAAAATCTGCCGTAAC
TGTAAAGTTATCAAGCGTAA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAKKPGKDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFDQQKGTIVEMFNMFSGGALERASILAL
GIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPNMVDNLVVINQTMFTLIATV
SLVTGTMFLMWLGEQITERGIGNGISILIFAGIVAGLPSAIGQTIEQARQGELHVLLLLFIAVLSFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSAFGWLTDVSLALSPGQPLYVM
LYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRF
YFGGTSLLIVVVVIMDFMAQVQTHLMSQQYDSVLKKANLKGYGR

Sequences:

>Translated_444_residues
MAKKPGKDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFDQQKGTIVEMFNMFSGGALERASILAL
GIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPNMVDNLVVINQTMFTLIATV
SLVTGTMFLMWLGEQITERGIGNGISILIFAGIVAGLPSAIGQTIEQARQGELHVLLLLFIAVLSFAVIYFVVFMERGQR
RIVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSAFGWLTDVSLALSPGQPLYVM
LYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRF
YFGGTSLLIVVVVIMDFMAQVQTHLMSQQYDSVLKKANLKGYGR
>Mature_443_residues
AKKPGKDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFDQQKGTIVEMFNMFSGGALERASILALG
IMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYTRYGTLVLATFQAIGIATGLPNMVDNLVVINQTMFTLIATVS
LVTGTMFLMWLGEQITERGIGNGISILIFAGIVAGLPSAIGQTIEQARQGELHVLLLLFIAVLSFAVIYFVVFMERGQRR
IVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSAFGWLTDVSLALSPGQPLYVML
YAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRFY
FGGTSLLIVVVVIMDFMAQVQTHLMSQQYDSVLKKANLKGYGR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=446, Percent_Identity=80.9417040358744, Blast_Score=672, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48516; Mature: 48385

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKKPGKDFRSAQSGLSELKSRLLFVIGALLVFRAGSFVPIPGIDAAVLADLFDQQKGTI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHH
VEMFNMFSGGALERASILALGIMPYISASIVVQLLTVVHPALAELKKEGEAGRRKISQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGTLVLATFQAIGIATGLPNMVDNLVVINQTMFTLIATVSLVTGTMFLMWLGEQITERG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGNGISILIFAGIVAGLPSAIGQTIEQARQGELHVLLLLFIAVLSFAVIYFVVFMERGQR
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RIVVNYAKRQQGRKVFAAQSSHLPLKINMAGVIPAIFASSIILFPGTLAQWFGQNGESSA
EEEEEHHHHHCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCC
FGWLTDVSLALSPGQPLYVMLYAAAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPG
CHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
EQTAKYIDKVMTRLTLAGALYITFICLIPEFMMVAWNVRFYFGGTSLLIVVVVIMDFMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHH
VQTHLMSQQYDSVLKKANLKGYGR
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9322765; 10952301 [H]