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The map label for this gene is cysC [H]

Identifier: 218710703

GI number: 218710703

Start: 2948983

End: 2949603

Strand: Reverse

Name: cysC [H]

Synonym: VS_2786

Alternate gene names: 218710703

Gene position: 2949603-2948983 (Counterclockwise)

Preceding gene: 218710704

Following gene: 218710694

Centisome position: 89.4

GC content: 46.86

Gene sequence:

>621_bases
ATGACCGCAGTACTCAAACCAAAAGATGAGAATGTTGTGTGGCATCAACATTCGATTGATAAAACATTTCGTGCGGATCT
GAAATCACAGAAACCAGCTGTGCTCTGGTTCACTGGATTATCTGGTTCTGGGAAATCAACAGTTGCTGGAGCATTAGAAA
ACCGCTTAGCCCAACTTGGTTACCATACTTACTTATTGGATGGCGACAATGTCCGTCATGGGTTATGTAGCGACCTTGGC
TTCTCAGAGCAAGACCGTCGAGAGAATATTCGTCGTATTGGTGAGCTCGCTAAATTGATGGCGGATGCGGGTTTGATCGT
GTTGTCAGCGTTTATCTCTCCACATCAAGCGGAGAGACAGTTGGTACGTGATTTATTACCGGAAGGGGAGTTTCTTGAGG
TGTTTGTGAACACACCACTTGAGGTGTGTGAGCAGCGTGACCCGAAAGGCCTGTATAAGAAAGCACGAGCGGGAGAAATC
CCGAACTTCACGGGTATTAGCTCAGTGTACGAAGCGCCTCAGAGCCCTGAGATAGCTCTACCCGCGGGCGAAAAGACACT
CGATGAACTGGTCGAATTGTGTATTGAGGCTTTAGAGAAGCGTAATATTTTATCCAATTGA

Upstream 100 bases:

>100_bases
ACGTATCGGCATCCCAATCTCGATTGTCTATTCGGGCTTGGTGCTGACCCTGATTCCTTACTTTTTCCCATTTTAATGCT
GTTTATTTAAAGGACTAATT

Downstream 100 bases:

>100_bases
GATCGATGGTATGACTAAGGCTACTCTCCTGTTTATCTGCTTAATTCACTGCGGATAAATAGTGCAGCCTTGGTTTTCCG
AGACAAGAACCTTATCCTCT

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTAVLKPKDENVVWHQHSIDKTFRADLKSQKPAVLWFTGLSGSGKSTVAGALENRLAQLGYHTYLLDGDNVRHGLCSDLG
FSEQDRRENIRRIGELAKLMADAGLIVLSAFISPHQAERQLVRDLLPEGEFLEVFVNTPLEVCEQRDPKGLYKKARAGEI
PNFTGISSVYEAPQSPEIALPAGEKTLDELVELCIEALEKRNILSN

Sequences:

>Translated_206_residues
MTAVLKPKDENVVWHQHSIDKTFRADLKSQKPAVLWFTGLSGSGKSTVAGALENRLAQLGYHTYLLDGDNVRHGLCSDLG
FSEQDRRENIRRIGELAKLMADAGLIVLSAFISPHQAERQLVRDLLPEGEFLEVFVNTPLEVCEQRDPKGLYKKARAGEI
PNFTGISSVYEAPQSPEIALPAGEKTLDELVELCIEALEKRNILSN
>Mature_205_residues
TAVLKPKDENVVWHQHSIDKTFRADLKSQKPAVLWFTGLSGSGKSTVAGALENRLAQLGYHTYLLDGDNVRHGLCSDLGF
SEQDRRENIRRIGELAKLMADAGLIVLSAFISPHQAERQLVRDLLPEGEFLEVFVNTPLEVCEQRDPKGLYKKARAGEIP
NFTGISSVYEAPQSPEIALPAGEKTLDELVELCIEALEKRNILSN

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=203, Percent_Identity=47.7832512315271, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI34447231, Length=206, Percent_Identity=47.0873786407767, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI62912492, Length=206, Percent_Identity=47.0873786407767, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI1789107, Length=196, Percent_Identity=65.3061224489796, Blast_Score=265, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17542422, Length=207, Percent_Identity=50.2415458937198, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6322852, Length=197, Percent_Identity=51.2690355329949, Blast_Score=197, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24667040, Length=216, Percent_Identity=41.6666666666667, Blast_Score=171, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24667032, Length=200, Percent_Identity=43, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24667028, Length=200, Percent_Identity=43, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24667036, Length=200, Percent_Identity=43, Blast_Score=170, Evalue=5e-43,
Organism=Drosophila melanogaster, GI116007838, Length=200, Percent_Identity=43, Blast_Score=170, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24667044, Length=200, Percent_Identity=43, Blast_Score=170, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22852; Mature: 22721

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVLKPKDENVVWHQHSIDKTFRADLKSQKPAVLWFTGLSGSGKSTVAGALENRLAQLG
CCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHC
YHTYLLDGDNVRHGLCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLSAFISPHQAERQ
CEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHH
LVRDLLPEGEFLEVFVNTPLEVCEQRDPKGLYKKARAGEIPNFTGISSVYEAPQSPEIAL
HHHHHCCCCCEEEHHHCCCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEC
PAGEKTLDELVELCIEALEKRNILSN
CCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAVLKPKDENVVWHQHSIDKTFRADLKSQKPAVLWFTGLSGSGKSTVAGALENRLAQLG
CCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHC
YHTYLLDGDNVRHGLCSDLGFSEQDRRENIRRIGELAKLMADAGLIVLSAFISPHQAERQ
CEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHH
LVRDLLPEGEFLEVFVNTPLEVCEQRDPKGLYKKARAGEIPNFTGISSVYEAPQSPEIAL
HHHHHCCCCCEEEHHHCCCHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCEEC
PAGEKTLDELVELCIEALEKRNILSN
CCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]