Click here to switch to the map view.

The map label for this gene is lptA [H]

Identifier: 218710675

GI number: 218710675

Start: 2919680

End: 2920207

Strand: Direct

Name: lptA [H]

Synonym: VS_2755

Alternate gene names: 218710675

Gene position: 2919680-2920207 (Clockwise)

Preceding gene: 218710674

Following gene: 218710676

Centisome position: 88.49

GC content: 41.48

Gene sequence:

>528_bases
ATGCAACTCTCTTTAATTCTGTTCAGGGTAGATATGAAACTCTCACACCTTAGTTTATTGGCTTTGACCCTTGCGGCGTC
TAATGTCTATGCTCTATCTTCGGATAGCGAGCAGCCTGTCTATATTGATTCAGACAGTCAGCAATTAGATATGAAAAGCA
ATCAAGTAACCTTTCTTGGCGATGTGAACCTTAAACAAGGTAGCATCAATATCAATGCCGATAAGGTCATTGTTACACGT
AATGCCGTCAACGGTGAAATTGAAGAAATACAAGGTTTCGGAAAGCCCGCAACCTTTTCTCAACTTACTGACGATGGGAA
AACACTCTATGGTGAAGCTGACGATTTACATTACCAGCTGATTGCCGATAGATTGATCATGACTAAGAACGCGATGCTAT
CTCAAGATGGCAGTATCATTCGTGGCTCTAAGATTACCTATCAGATCACCTCTCAAAAGTTGGTTGCCGATAGTGATAGC
AGTGAGCGAGTATCAACGGTTTTACAACCAGCGGAAGTGAATAAGTAA

Upstream 100 bases:

>100_bases
CTGACTAGCCGAGATTTTTATTCAGACACTCCGGTCCATATGATCGGTACATTTTTTGAAAATGAGGGGCAAGCAATGAA
AGGGAACTTCGGTACCAACA

Downstream 100 bases:

>100_bases
TCATGGCAGTCCTTACAGCAAAGAACCTAGCGAAGACCTACGGAAAACGTAAAGTTGTAACAGACGTAAGCTTACAAGTA
GAGTCAGGTCAGATCGTAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MQLSLILFRVDMKLSHLSLLALTLAASNVYALSSDSEQPVYIDSDSQQLDMKSNQVTFLGDVNLKQGSININADKVIVTR
NAVNGEIEEIQGFGKPATFSQLTDDGKTLYGEADDLHYQLIADRLIMTKNAMLSQDGSIIRGSKITYQITSQKLVADSDS
SERVSTVLQPAEVNK

Sequences:

>Translated_175_residues
MQLSLILFRVDMKLSHLSLLALTLAASNVYALSSDSEQPVYIDSDSQQLDMKSNQVTFLGDVNLKQGSININADKVIVTR
NAVNGEIEEIQGFGKPATFSQLTDDGKTLYGEADDLHYQLIADRLIMTKNAMLSQDGSIIRGSKITYQITSQKLVADSDS
SERVSTVLQPAEVNK
>Mature_175_residues
MQLSLILFRVDMKLSHLSLLALTLAASNVYALSSDSEQPVYIDSDSQQLDMKSNQVTFLGDVNLKQGSININADKVIVTR
NAVNGEIEEIQGFGKPATFSQLTDDGKTLYGEADDLHYQLIADRLIMTKNAMLSQDGSIIRGSKITYQITSQKLVADSDS
SERVSTVLQPAEVNK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=156, Percent_Identity=48.7179487179487, Blast_Score=149, Evalue=7e-38,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 19186; Mature: 19186

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSLILFRVDMKLSHLSLLALTLAASNVYALSSDSEQPVYIDSDSQQLDMKSNQVTFLG
CCEEEEEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCEEECCCCCEECCCCCEEEEEE
DVNLKQGSININADKVIVTRNAVNGEIEEIQGFGKPATFSQLTDDGKTLYGEADDLHYQL
CCEEECCEEEECCCEEEEEECCCCCCHHHHHCCCCCCCHHHHCCCCCEEECCCCCHHHHH
IADRLIMTKNAMLSQDGSIIRGSKITYQITSQKLVADSDSSERVSTVLQPAEVNK
HHHHHHHHCCCCCCCCCCEEECCEEEEEEECCEEEECCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MQLSLILFRVDMKLSHLSLLALTLAASNVYALSSDSEQPVYIDSDSQQLDMKSNQVTFLG
CCEEEEEEEECCCHHHHHHHHHHHHHCCEEEECCCCCCCEEECCCCCEECCCCCEEEEEE
DVNLKQGSININADKVIVTRNAVNGEIEEIQGFGKPATFSQLTDDGKTLYGEADDLHYQL
CCEEECCEEEECCCEEEEEECCCCCCHHHHHCCCCCCCHHHHCCCCCEEECCCCCHHHHH
IADRLIMTKNAMLSQDGSIIRGSKITYQITSQKLVADSDSSERVSTVLQPAEVNK
HHHHHHHHCCCCCCCCCCEEECCEEEEEEECCEEEECCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]