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The map label for this gene is yggV [C]

Identifier: 218710634

GI number: 218710634

Start: 2874466

End: 2875065

Strand: Direct

Name: yggV [C]

Synonym: VS_2688

Alternate gene names: 218710634

Gene position: 2874466-2875065 (Clockwise)

Preceding gene: 218710633

Following gene: 218710635

Centisome position: 87.12

GC content: 46.67

Gene sequence:

>600_bases
ATGAGTAAGATTGTTTTAGCAACAGGCAACCAAGGCAAAGTTCGCGAGATGGCAGATATTCTGTCTGAGTTTGGTTTCGA
CGTTGTCGCGCAAAGTGAATTTAACGTTTCAGAAGTCGCAGAAACAGGGACGACTTTCATTGAAAATGCCATCATCAAAG
CTCGCCACGCTGCGAAAGAGACGGGGCTACCAGCCATTGCTGACGATTCTGGCTTAGAAGTTGATTACCTTAATGGTGCA
CCCGGTATCTACTCAGCGCGTTACTCCGGTGAAGGGGCTACTGATAAGCAAAACATCGAAAAGCTGTTAGATGCTATGCA
AGGTGTCGATGTTGAAAAGCGTACCGCTCGTTTTCACTGTGTATTGGTGTTAATGCGTCACGAAAACGATCCAACTCCAT
TAGTATGTCACGGTAAATGGGAAGGTCGCATTCTGACTGAAGAACACGGTGGGAATGGCTTTGGCTACGATCCTGTATTC
TTTGTACCCGAAGATAACTGCGCCTCAGCAGAACTTGAATCGTCACGTAAGAAGCAACTGTCACACCGTGGTAAAGCCCT
CGCGTCATTATTCAAGACTCTCAAGGAGCAAGCTCTGTAA

Upstream 100 bases:

>100_bases
GAAAGGCACAGGTCCACTGCGTTTCACACAAAAATTCTATATAGAAGAGTAGCTTCAAAGCTCACATTTCTAGTCATTAA
CTTATTAGAGCCACATCCCC

Downstream 100 bases:

>100_bases
TGCACAATGCAGCGCTAATACCACCCGCACTCAGCCTCTATGTCCACATTCCATGGTGTGTACAAAAGTGTCCGTATTGT
GATTTTAACTCTCACGCTCT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSKIVLATGNQGKVREMADILSEFGFDVVAQSEFNVSEVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDYLNGA
PGIYSARYSGEGATDKQNIEKLLDAMQGVDVEKRTARFHCVLVLMRHENDPTPLVCHGKWEGRILTEEHGGNGFGYDPVF
FVPEDNCASAELESSRKKQLSHRGKALASLFKTLKEQAL

Sequences:

>Translated_199_residues
MSKIVLATGNQGKVREMADILSEFGFDVVAQSEFNVSEVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDYLNGA
PGIYSARYSGEGATDKQNIEKLLDAMQGVDVEKRTARFHCVLVLMRHENDPTPLVCHGKWEGRILTEEHGGNGFGYDPVF
FVPEDNCASAELESSRKKQLSHRGKALASLFKTLKEQAL
>Mature_198_residues
SKIVLATGNQGKVREMADILSEFGFDVVAQSEFNVSEVAETGTTFIENAIIKARHAAKETGLPAIADDSGLEVDYLNGAP
GIYSARYSGEGATDKQNIEKLLDAMQGVDVEKRTARFHCVLVLMRHENDPTPLVCHGKWEGRILTEEHGGNGFGYDPVFF
VPEDNCASAELESSRKKQLSHRGKALASLFKTLKEQAL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=63.0769230769231, Blast_Score=262, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21729; Mature: 21597

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIVLATGNQGKVREMADILSEFGFDVVAQSEFNVSEVAETGTTFIENAIIKARHAAKE
CCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDYLNGAPGIYSARYSGEGATDKQNIEKLLDAMQGVDVEKRTARFHC
CCCCCEECCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEE
VLVLMRHENDPTPLVCHGKWEGRILTEEHGGNGFGYDPVFFVPEDNCASAELESSRKKQL
EEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
SHRGKALASLFKTLKEQAL
HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKIVLATGNQGKVREMADILSEFGFDVVAQSEFNVSEVAETGTTFIENAIIKARHAAKE
CEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPAIADDSGLEVDYLNGAPGIYSARYSGEGATDKQNIEKLLDAMQGVDVEKRTARFHC
CCCCCEECCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHEEE
VLVLMRHENDPTPLVCHGKWEGRILTEEHGGNGFGYDPVFFVPEDNCASAELESSRKKQL
EEEEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHH
SHRGKALASLFKTLKEQAL
HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]