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The map label for this gene is tkt1 [H]

Identifier: 218710601

GI number: 218710601

Start: 2840565

End: 2842577

Strand: Reverse

Name: tkt1 [H]

Synonym: VS_2654

Alternate gene names: 218710601

Gene position: 2842577-2840565 (Counterclockwise)

Preceding gene: 218710621

Following gene: 218710599

Centisome position: 86.16

GC content: 49.48

Gene sequence:

>2013_bases
ATGTATCCAGGAGCAGACATGCCTTCTCGTAAAGATCTAGCCAATGCAATCCGCGCACTTAGCATGGACGGTGTTCAACA
AGCAAACTCAGGCCACCCAGGCGCACCTATGGGTATGGCTGACATCGCTGAAGTTCTTTGGCGTGGCCACTTGAACCATA
ACCCATCAAACCCAGAGTGGGCTGACCGTGACCGTTTTATCCTGTCTAACGGTCATGGTTCTATGCTGATTTACTCTCTG
CTTCACTTAGCAGGTTACGAGCTTTCAATTGAAGACCTAAAAAACTTCCGTCAACTGCACTCTAAGACTCCAGGTCACCC
AGAGTACGGTTACGCTCCTGGTATCGAGACAACGACTGGTCCTCTGGGTCAAGGCATCACCAACGCTGTTGGTATGGCGA
TGGCTGAAAAATCATTGGCTGCACAGTTCAACAAAGAAGGCCACGACATCGTCGATCACTTCACTTATGCGTTCATGGGT
GATGGTTGTTTGATGGAAGGTATTTCTCACGAAGCATGTTCTCTAGCGGGTACGCTAGGTCTTGGTAAGCTGGTTGCTTT
CTGGGATGACAACGGCATCTCTATCGATGGCGAAGTTGAAGGTTGGTTCTCTGACGATACACCTAAGCGTTTTGAAGCTT
ACGGCTGGCACGTAATCCCAGCAGTTGATGGTCACGATGCTGACGCAATCAATGCGGCTATCGAAGCGGCTAAAGCGGAT
CCTCGTCCAACACTTATCTGTACTAAGACTATTATCGGTTTTGGTTCACCAAATAAAGCGGGTACGCACGACTGTCACGG
TGCTCCACTAGGTGCTGATGAAATCACAGCAACTAAAGCGGCGCTTGGTTGGGAACACGGTCCTTTCGAAATCCCGGCTG
ATATCGCAGCTGAGTGGAATGCGAAAGAAGCGGGCGCAGCGAAAGAAGCGGCTTGGAATGCTAAGTTTGACGCATACGCA
GCAGCTCACCCAGAGCTAGCAGCAGAATTTAAACGTCGTACTAACGGCGAGCTTCCAGCTGAGTGGGAAGAGAAAGCAAA
CGCAATCATTGCTGATCTTCAAGCTAACCCAGCAAACATCGCATCACGTAAAGCATCTCAAAATGCTCTAGAAGCATTCG
GTGCTATGCTACCTGAATTCATGGGCGGCTCTGCTGACCTTGCGCCTTCTAACCTGACTATGTGGTCTGGTTCTAAGTCG
CTTGAAGCGAACGACTTCTCAGGTAACTACATCCACTACGGTGTACGTGAATTCGGTATGACTGCAATCATGAACGGTAT
CGCTCTGCACGGTGGTTTCGTACCATACGGCGCAACGTTCCTAATGTTCATGGAATACGCACGTAACGCGATGCGTATGG
CTGCTCTGATGAAAGTTCAGAACATCCAAGTTTACACGCACGACTCTATCGGCCTAGGCGAAGATGGTCCTACTCACCAA
CCGGTTGAGCAGATCGCTTCTCTACGTCTGACTCCAAACATGAGCACATGGCGCCCATGTGACCAAGTTGAGTCTGCTGT
TGCTTGGAAACTAGCAATCGAACGCAAAGATGGTCCTTCTGCACTTATCTTCTCTCGTCAAAACCTTGCACAGCAAGACC
GTGACGCTGAGCAAGTAGCTAACATCGCCAAGGGTGGTTACATTCTGAAAGATTGTGAAGGCAAACCAGAGCTTATCCTT
ATCGCTACAGGTTCTGAAGTTGAGCTAGCGGTTAGCGCTGCTGCTGAACTAACAGCTGAAGGCAAGAAAGTACGCGTAGT
ATCTATGCCTGCTACTGACGCGTTCGATAAGCAAGACGCCGAGTACCGTGAGTCTGTACTGCCATCTGACGTTACAGCGC
GTATCGCAGTAGAAGCTGGTATCGCTGACTTCTGGTACAAATACGTTGGTTTCGGTGGCAAGATCATCGGCATGACAACG
TTCGGCGAATCTGCACCAGCAGGCGAGCTATTCAAGATGTTCGGTTTCACTACTGAAAACGTAGTAAACACTGCAAAAGA
GCTTCTTGCTTAA

Upstream 100 bases:

>100_bases
AAGTGCCAGTAAAACGTTTGCAGTCGCTATAGTCGTTTGAGAGAATACCCGCGCTAATAAAAATGAAAACTTTAGCATCT
ATCTCTTTTTTAAATCGCTT

Downstream 100 bases:

>100_bases
TCATTCGTTGTAACGCGAATAGAAAAAAACCGAGCCACTGGCTCGGTTTTTTATTTGGCTTTCAGAAACATGAGTTACTC
GAATTCATTTCCCCAATTAT

Product: transketolase

Products: NA

Alternate protein names: TK 1 [H]

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MYPGADMPSRKDLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEWADRDRFILSNGHGSMLIYSL
LHLAGYELSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKSLAAQFNKEGHDIVDHFTYAFMG
DGCLMEGISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAD
PRPTLICTKTIIGFGSPNKAGTHDCHGAPLGADEITATKAALGWEHGPFEIPADIAAEWNAKEAGAAKEAAWNAKFDAYA
AAHPELAAEFKRRTNGELPAEWEEKANAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKS
LEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQ
PVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGKPELIL
IATGSEVELAVSAAAELTAEGKKVRVVSMPATDAFDKQDAEYRESVLPSDVTARIAVEAGIADFWYKYVGFGGKIIGMTT
FGESAPAGELFKMFGFTTENVVNTAKELLA

Sequences:

>Translated_670_residues
MYPGADMPSRKDLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEWADRDRFILSNGHGSMLIYSL
LHLAGYELSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKSLAAQFNKEGHDIVDHFTYAFMG
DGCLMEGISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAD
PRPTLICTKTIIGFGSPNKAGTHDCHGAPLGADEITATKAALGWEHGPFEIPADIAAEWNAKEAGAAKEAAWNAKFDAYA
AAHPELAAEFKRRTNGELPAEWEEKANAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKS
LEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQ
PVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGKPELIL
IATGSEVELAVSAAAELTAEGKKVRVVSMPATDAFDKQDAEYRESVLPSDVTARIAVEAGIADFWYKYVGFGGKIIGMTT
FGESAPAGELFKMFGFTTENVVNTAKELLA
>Mature_670_residues
MYPGADMPSRKDLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEWADRDRFILSNGHGSMLIYSL
LHLAGYELSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKSLAAQFNKEGHDIVDHFTYAFMG
DGCLMEGISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAD
PRPTLICTKTIIGFGSPNKAGTHDCHGAPLGADEITATKAALGWEHGPFEIPADIAAEWNAKEAGAAKEAAWNAKFDAYA
AAHPELAAEFKRRTNGELPAEWEEKANAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKS
LEANDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQ
PVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGKPELIL
IATGSEVELAVSAAAELTAEGKKVRVVSMPATDAFDKQDAEYRESVLPSDVTARIAVEAGIADFWYKYVGFGGKIIGMTT
FGESAPAGELFKMFGFTTENVVNTAKELLA

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=677, Percent_Identity=27.178729689808, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI4507521, Length=677, Percent_Identity=27.178729689808, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI133778974, Length=678, Percent_Identity=24.6312684365782, Blast_Score=142, Evalue=1e-33,
Organism=Escherichia coli, GI48994911, Length=664, Percent_Identity=76.5060240963855, Blast_Score=1077, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=662, Percent_Identity=70.6948640483384, Blast_Score=996, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=680, Percent_Identity=25.8823529411765, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=668, Percent_Identity=48.9520958083832, Blast_Score=606, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6319593, Length=668, Percent_Identity=45.6586826347305, Blast_Score=563, Evalue=1e-161,
Organism=Drosophila melanogaster, GI45551847, Length=689, Percent_Identity=27.2859216255443, Blast_Score=169, Evalue=8e-42,
Organism=Drosophila melanogaster, GI45550715, Length=689, Percent_Identity=27.2859216255443, Blast_Score=169, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24666278, Length=671, Percent_Identity=25.3353204172876, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24645119, Length=651, Percent_Identity=26.7281105990783, Blast_Score=143, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 71991; Mature: 71991

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPGADMPSRKDLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEW
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
ADRDRFILSNGHGSMLIYSLLHLAGYELSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTG
CCCCCEEEECCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PLGQGITNAVGMAMAEKSLAAQFNKEGHDIVDHFTYAFMGDGCLMEGISHEACSLAGTLG
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCC
LGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAD
CCCEEEEECCCCEEECCCCCCCCCCCCCCHHHHCCCEEEECCCCCCHHHHHHHHHHHCCC
PRPTLICTKTIIGFGSPNKAGTHDCHGAPLGADEITATKAALGWEHGPFEIPADIAAEWN
CCCEEEEEEHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCC
AKEAGAAKEAAWNAKFDAYAAAHPELAAEFKRRTNGELPAEWEEKANAIIADLQANPANI
CHHCCCHHHHHCCCCCCHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCEEEEECCCCCHHH
ASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLEANDFSGNYIHYGVREFGM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHH
TAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCH
PVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQDRDAEQVA
HHHHHHHEECCCCCCCCCCHHHHHHHHEEEEEEECCCCCCEEEEEHHHHHHHCCCHHHHH
NIAKGGYILKDCEGKPELILIATGSEVELAVSAAAELTAEGKKVRVVSMPATDAFDKQDA
HHHCCCEEEECCCCCCCEEEEECCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCH
EYRESVLPSDVTARIAVEAGIADFWYKYVGFGGKIIGMTTFGESAPAGELFKMFGFTTEN
HHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHH
VVNTAKELLA
HHHHHHHHHC
>Mature Secondary Structure
MYPGADMPSRKDLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEW
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
ADRDRFILSNGHGSMLIYSLLHLAGYELSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTG
CCCCCEEEECCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
PLGQGITNAVGMAMAEKSLAAQFNKEGHDIVDHFTYAFMGDGCLMEGISHEACSLAGTLG
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHCC
LGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAD
CCCEEEEECCCCEEECCCCCCCCCCCCCCHHHHCCCEEEECCCCCCHHHHHHHHHHHCCC
PRPTLICTKTIIGFGSPNKAGTHDCHGAPLGADEITATKAALGWEHGPFEIPADIAAEWN
CCCEEEEEEHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCC
AKEAGAAKEAAWNAKFDAYAAAHPELAAEFKRRTNGELPAEWEEKANAIIADLQANPANI
CHHCCCHHHHHCCCCCCHHHCCCHHHHHHHHHHCCCCCCCHHHHCCCEEEEECCCCCHHH
ASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLEANDFSGNYIHYGVREFGM
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEECHHHHHH
TAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQ
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCH
PVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQDRDAEQVA
HHHHHHHEECCCCCCCCCCHHHHHHHHEEEEEEECCCCCCEEEEEHHHHHHHCCCHHHHH
NIAKGGYILKDCEGKPELILIATGSEVELAVSAAAELTAEGKKVRVVSMPATDAFDKQDA
HHHCCCEEEECCCCCCCEEEEECCCCEEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCH
EYRESVLPSDVTARIAVEAGIADFWYKYVGFGGKIIGMTTFGESAPAGELFKMFGFTTEN
HHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCHHH
VVNTAKELLA
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA