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The map label for this gene is coaE [H]

Identifier: 218710512

GI number: 218710512

Start: 2743832

End: 2744098

Strand: Direct

Name: coaE [H]

Synonym: VS_2551

Alternate gene names: 218710512

Gene position: 2743832-2744098 (Clockwise)

Preceding gene: 218710511

Following gene: 218710513

Centisome position: 83.16

GC content: 47.57

Gene sequence:

>267_bases
ATGGCAATCATTATCGGATTAAGCGGTGGGATCGCCAGTGGTAAAACCACAGTAGCCAACCTGTTCAATGAGCATTTCAA
TATTGATATTGTCGATGCTGATATCGTGGCACGCGAAGTGGTGGCGTTGGGCAGTGAAGGTCTAAAACAGATTGCGACCC
ATTTTGGTGAAGAGGTATTGCTCGAAGATGGGGCGCTGAACCGAGCTAAATTGCGCGAAGTGATCTTTTCTGATCCCCGA
TCCCACAGAGAAACAATGGCTCAATGA

Upstream 100 bases:

>100_bases
TCCCATTTGGACCTTACCTGGCGATTGCGGGTTGGGTAAGTTTGATGTGGGGCAATGACATCATGGGTTGGTATTTCACT
TCTGTACTAGGGATTTAATC

Downstream 100 bases:

>100_bases
ACTGCTTCACCCTATGATCCGCGACAAAATTGACAGTGACCTGTCTAAAATCACATCCCCATATGGTTTATTAGTCGCAC
CACTATTGGTTGAAAACCAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 88; Mature: 87

Protein sequence:

>88_residues
MAIIIGLSGGIASGKTTVANLFNEHFNIDIVDADIVAREVVALGSEGLKQIATHFGEEVLLEDGALNRAKLREVIFSDPR
SHRETMAQ

Sequences:

>Translated_88_residues
MAIIIGLSGGIASGKTTVANLFNEHFNIDIVDADIVAREVVALGSEGLKQIATHFGEEVLLEDGALNRAKLREVIFSDPR
SHRETMAQ
>Mature_87_residues
AIIIGLSGGIASGKTTVANLFNEHFNIDIVDADIVAREVVALGSEGLKQIATHFGEEVLLEDGALNRAKLREVIFSDPRS
HRETMAQ

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=76, Percent_Identity=43.421052631579, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI191252795, Length=76, Percent_Identity=43.421052631579, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786292, Length=79, Percent_Identity=50.6329113924051, Blast_Score=81, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554944, Length=83, Percent_Identity=40.9638554216867, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=87, Percent_Identity=41.3793103448276, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644728, Length=97, Percent_Identity=39.1752577319588, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 9489; Mature: 9358

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIIGLSGGIASGKTTVANLFNEHFNIDIVDADIVAREVVALGSEGLKQIATHFGEEVL
CEEEEECCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHCHHHHHHHHHHCCHHEE
LEDGALNRAKLREVIFSDPRSHRETMAQ
CCCCCCCHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
AIIIGLSGGIASGKTTVANLFNEHFNIDIVDADIVAREVVALGSEGLKQIATHFGEEVL
EEEEECCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHHCHHHHHHHHHHCCHHEE
LEDGALNRAKLREVIFSDPRSHRETMAQ
CCCCCCCHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]