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The map label for this gene is kefC [H]

Identifier: 218710230

GI number: 218710230

Start: 2432028

End: 2433614

Strand: Direct

Name: kefC [H]

Synonym: VS_2263

Alternate gene names: 218710230

Gene position: 2432028-2433614 (Clockwise)

Preceding gene: 218710229

Following gene: 218710231

Centisome position: 73.71

GC content: 44.61

Gene sequence:

>1587_bases
ATGGAACTTATATTAATATCCACTGCGTTTATCGCAGGATTTATTGCTTTAAAATGCCACCTCCCCCCATTAGTTGGTTT
TTTGGTTGCAGGTTTCGGGCTTTATGCCCTTGGCTTTGAAACCAATGACACCATCATTACTTTGGCTGACCTTGGTGTCA
CCCTTCTCTTATTTACTATTGGCTTAAAGCTGGACATCAAAACCCTACTCTCTAAAGAGATCTGGGCTGGCGCAACAATC
CACAATCTTTTATCCACTCTGTTTTTTGCAGCCGCTCTATTTGGTTTTAAGTTTCTAGGTATTTCATCTCTAGCAGCCAT
GTCAATAGAACAGATCGTTCTACTCGGTTTTGCTCTTTCATTTTCTAGTACTGTATTTGCGGTCAAGTCTCTACAAGAGA
AAGGGGAAATGAATGCTACCTATGGCACACTAGCGATTGGCATTCTGGTCATGCAAGATATCTTTGCTGTCGTATTCTTG
ACTGCATCGACGGGCAAAATTCCAGAGTGGTATGCGATCGCACTGTTCGCTTTGCCTTTCTTTCGCCCATTGTTCTACAA
AGTCCTCGATTGGGTTGGGCACGGTGAAATGTTGGTGCTATTCGGTATCTTCTTCGCATTAGTTGTTGGTGCTGGCTTGT
TCCAGTTTGTAGGAGTAAAACCAGACTTAGGTGCCCTTATCCTAGGTATGCTGTTAGCCGGTCACCCAAAAGCTTCAGAG
CTATCGAAGTCGCTGTTTAACCTTAAAGAGCTTTTCCTCGTCTGCTTCTTCTTGAATATTGGCTTGTCAGAACAGCCAAC
TATTCAGGGTTTTATGCTTGCAGTATTGTTCTTATTGTTACTGCCAGTGAAAGGCGTTCTGTACTTCTTGGTACTAAACC
GATTCAAGTTCCGTGTTCGAACCTCCCTACTCACTTCTTTGTCACTGTTTAACTACAGTGAATTTGGCCTCATCGTCGGT
GGCCTTGCTTTTAAGATGGGCTGGATGTCTGGCGACATCTTGGTAGCAGTGGCTATAGCCGTTTCATTGTCGTTCTTAAT
CGCTGCACCTCTCAACAAAGCGGGTCACAAACTTTATCAACAATCAGGTCGCTGGTTAAAAGAGCACGCTGCTGAGAAGC
TCCACCAACGTGACAAACGAATTGACCCAGGTCGGGCTCAGGTTCTAATTCTTGGCATGGGACGCATTGGTACTGGTGCC
TACGACGAATTACGCTCACGCTACGGCAAAGTGAGTTTAGGTGTCGAAGTTCGTGAAGACGCGGCACATAACCACAGAAG
CCATGGCAGAAACGTTATTTCTGGTGACGCAACTGACCCGGATTTCTGGGAACGAATTTTAGACACAGCAAACGTAAAAC
TGGTGATCTTGGCTATGCCTCACCACCAGGGTAATCAAACCGCCTTAGAACAATTAAAATCACGAAACTTTAAAGGTCAA
ATAGCGGCAATTGCCGAATATCCAGATCAGCTCGAAACACTGAAAGAGAATGGCGTCGATGCGGCATTTAACATTTACAG
CGAAGCTGGCAGCGGTTTTGCCCGACATGTTTGTGAACAATTGAATCCGAACATCAATAAAATATAA

Upstream 100 bases:

>100_bases
AGCTTCTTGAAGACTAAAGAAAACAATTCTGATTTTCCGCGGGCCGTGTTTGTATAAACACGGCCCGTTTTTTTAAGCTA
GGGAACTACAACAACAAGTT

Downstream 100 bases:

>100_bases
TATTCAACATGTTCCATTCAACCTCTCAAAATTGCGCTTTTTTTGCACTTTTGAGAGGTTTTTGTTCAAAAAACCAACCG
CAATTAGACACCACTCACCA

Product: putative glutathione-regulated potassium-efflux system protein KefB

Products: NA

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MELILISTAFIAGFIALKCHLPPLVGFLVAGFGLYALGFETNDTIITLADLGVTLLLFTIGLKLDIKTLLSKEIWAGATI
HNLLSTLFFAAALFGFKFLGISSLAAMSIEQIVLLGFALSFSSTVFAVKSLQEKGEMNATYGTLAIGILVMQDIFAVVFL
TASTGKIPEWYAIALFALPFFRPLFYKVLDWVGHGEMLVLFGIFFALVVGAGLFQFVGVKPDLGALILGMLLAGHPKASE
LSKSLFNLKELFLVCFFLNIGLSEQPTIQGFMLAVLFLLLLPVKGVLYFLVLNRFKFRVRTSLLTSLSLFNYSEFGLIVG
GLAFKMGWMSGDILVAVAIAVSLSFLIAAPLNKAGHKLYQQSGRWLKEHAAEKLHQRDKRIDPGRAQVLILGMGRIGTGA
YDELRSRYGKVSLGVEVREDAAHNHRSHGRNVISGDATDPDFWERILDTANVKLVILAMPHHQGNQTALEQLKSRNFKGQ
IAAIAEYPDQLETLKENGVDAAFNIYSEAGSGFARHVCEQLNPNINKI

Sequences:

>Translated_528_residues
MELILISTAFIAGFIALKCHLPPLVGFLVAGFGLYALGFETNDTIITLADLGVTLLLFTIGLKLDIKTLLSKEIWAGATI
HNLLSTLFFAAALFGFKFLGISSLAAMSIEQIVLLGFALSFSSTVFAVKSLQEKGEMNATYGTLAIGILVMQDIFAVVFL
TASTGKIPEWYAIALFALPFFRPLFYKVLDWVGHGEMLVLFGIFFALVVGAGLFQFVGVKPDLGALILGMLLAGHPKASE
LSKSLFNLKELFLVCFFLNIGLSEQPTIQGFMLAVLFLLLLPVKGVLYFLVLNRFKFRVRTSLLTSLSLFNYSEFGLIVG
GLAFKMGWMSGDILVAVAIAVSLSFLIAAPLNKAGHKLYQQSGRWLKEHAAEKLHQRDKRIDPGRAQVLILGMGRIGTGA
YDELRSRYGKVSLGVEVREDAAHNHRSHGRNVISGDATDPDFWERILDTANVKLVILAMPHHQGNQTALEQLKSRNFKGQ
IAAIAEYPDQLETLKENGVDAAFNIYSEAGSGFARHVCEQLNPNINKI
>Mature_528_residues
MELILISTAFIAGFIALKCHLPPLVGFLVAGFGLYALGFETNDTIITLADLGVTLLLFTIGLKLDIKTLLSKEIWAGATI
HNLLSTLFFAAALFGFKFLGISSLAAMSIEQIVLLGFALSFSSTVFAVKSLQEKGEMNATYGTLAIGILVMQDIFAVVFL
TASTGKIPEWYAIALFALPFFRPLFYKVLDWVGHGEMLVLFGIFFALVVGAGLFQFVGVKPDLGALILGMLLAGHPKASE
LSKSLFNLKELFLVCFFLNIGLSEQPTIQGFMLAVLFLLLLPVKGVLYFLVLNRFKFRVRTSLLTSLSLFNYSEFGLIVG
GLAFKMGWMSGDILVAVAIAVSLSFLIAAPLNKAGHKLYQQSGRWLKEHAAEKLHQRDKRIDPGRAQVLILGMGRIGTGA
YDELRSRYGKVSLGVEVREDAAHNHRSHGRNVISGDATDPDFWERILDTANVKLVILAMPHHQGNQTALEQLKSRNFKGQ
IAAIAEYPDQLETLKENGVDAAFNIYSEAGSGFARHVCEQLNPNINKI

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=532, Percent_Identity=25, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786232, Length=534, Percent_Identity=26.5917602996255, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1789749, Length=494, Percent_Identity=25.9109311740891, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 57813; Mature: 57813

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELILISTAFIAGFIALKCHLPPLVGFLVAGFGLYALGFETNDTIITLADLGVTLLLFTI
CEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHH
GLKLDIKTLLSKEIWAGATIHNLLSTLFFAAALFGFKFLGISSLAAMSIEQIVLLGFALS
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSTVFAVKSLQEKGEMNATYGTLAIGILVMQDIFAVVFLTASTGKIPEWYAIALFALPF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FRPLFYKVLDWVGHGEMLVLFGIFFALVVGAGLFQFVGVKPDLGALILGMLLAGHPKASE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
LSKSLFNLKELFLVCFFLNIGLSEQPTIQGFMLAVLFLLLLPVKGVLYFLVLNRFKFRVR
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLLTSLSLFNYSEFGLIVGGLAFKMGWMSGDILVAVAIAVSLSFLIAAPLNKAGHKLYQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QSGRWLKEHAAEKLHQRDKRIDPGRAQVLILGMGRIGTGAYDELRSRYGKVSLGVEVRED
HHCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEECEEECHH
AAHNHRSHGRNVISGDATDPDFWERILDTANVKLVILAMPHHQGNQTALEQLKSRNFKGQ
HHHCHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCC
IAAIAEYPDQLETLKENGVDAAFNIYSEAGSGFARHVCEQLNPNINKI
CHHHHHCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MELILISTAFIAGFIALKCHLPPLVGFLVAGFGLYALGFETNDTIITLADLGVTLLLFTI
CEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCCCCEEEHHHHHHHHHHHHH
GLKLDIKTLLSKEIWAGATIHNLLSTLFFAAALFGFKFLGISSLAAMSIEQIVLLGFALS
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSTVFAVKSLQEKGEMNATYGTLAIGILVMQDIFAVVFLTASTGKIPEWYAIALFALPF
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
FRPLFYKVLDWVGHGEMLVLFGIFFALVVGAGLFQFVGVKPDLGALILGMLLAGHPKASE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
LSKSLFNLKELFLVCFFLNIGLSEQPTIQGFMLAVLFLLLLPVKGVLYFLVLNRFKFRVR
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLLTSLSLFNYSEFGLIVGGLAFKMGWMSGDILVAVAIAVSLSFLIAAPLNKAGHKLYQ
HHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QSGRWLKEHAAEKLHQRDKRIDPGRAQVLILGMGRIGTGAYDELRSRYGKVSLGVEVRED
HHCHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCEEECEEECHH
AAHNHRSHGRNVISGDATDPDFWERILDTANVKLVILAMPHHQGNQTALEQLKSRNFKGQ
HHHCHHHCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCC
IAAIAEYPDQLETLKENGVDAAFNIYSEAGSGFARHVCEQLNPNINKI
CHHHHHCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA