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The map label for this gene is feoB [H]

Identifier: 218710201

GI number: 218710201

Start: 2397245

End: 2399518

Strand: Reverse

Name: feoB [H]

Synonym: VS_2233

Alternate gene names: 218710201

Gene position: 2399518-2397245 (Counterclockwise)

Preceding gene: 218710202

Following gene: 218710200

Centisome position: 72.73

GC content: 43.98

Gene sequence:

>2274_bases
ATGGATTATCAAGTTCTTACTGTTGGTAACCCTAATAGTGGTAAAACAACATTATTTAACGCATTAACTGGCGCAAAACA
GCACGTTGGTAACTGGGTTGGTGTGACCGTAGAAAAGAAAACCGGTTTATATTCGCACGCTGGTGATCAATTTCAGTTAA
CGGATTTACCAGGCATTTATGCACTAGACAGTGGCAATGATGCAAACAGTATCGATGAGTCTATTGCATCACGCGCCGTG
CTTACTCACCCAGCGGACGTGATCATCAATGTTGTTGATGCTAGCTGTTTGGAAAGAAGCTTATACATGACATTACAATT
GCGAGAGTTGGGTCGCCCAATGATCGTTGTATTGAACAAAATGGATGTATTAAAGCGTGAGCGTCAGGTGATTAATCTTA
AGGCTCTAGAAAAAGAGCTAGGTTGCCCGGTTCTAAGCTTGTCAGCAAACGATAAAGGACAAGTGGTTCGTTTTAAAGAG
CGTTTGCATAAGCTTCTGGTTCAAGGTGTGAGTCTTGATCCTATCTCTATTGATTACGATGTCGCGTTAGAAGCTCTTAT
TCCTTCTGTTGAGTCACAATTTGATGATGCTGACGTATCTCACCGAGCACTAGCGATTCGTGCTTTAGAAAATGATTACT
TGGTATTGAATGGTTTGGCTCCACAAACTCGCACTCAAATTGATAGTGTGCGTCTTGGTGCCGATTTCGATATTGATCTT
GCTGTTGCTGACGCTAAATACACTTTCTTACATGAACTTTGTAAACGAGTTCGTCGCAGCGAAGGCAAACTGAGCCGTAA
TTTCACAGAGAAAGCCGATCAATTCATTTTGAATAAATGGGTCGGGATTCCTTTCTTCTTCGTCATCATGTACCTAATGT
TTATGTTCTCTATCAATATCGGTAGCGCGTTTATCGACTTCTTCGATATTGGTGTTGGCGCAATATTAGTTGATGGCGGA
CATCACTTATTAGATGGTCACTTACCGGTTTGGCTAGTCACCGTTCTTGCTGATGGTATTGGTGGTGGTATCCAAACGGT
TGCGACCTTTATTCCGGTTATTGCCGCGCTTTACTTGTTCTTAGCGGTACTAGAAAGTTCAGGCTACATGGCCCGCGCTG
CATTTGTACTGGATAAAGTGATGCAGAAAATTGGCTTACCGGGCAAAGCATTTGTACCACTTGTTCTGGGTTTTGGCTGT
AACGTACCTTCTATCATGGCAACGCGTACTCTTGACCAAGAGCGCGAACGTAAACTCGCCGCATCAATGGCACCGTTTAT
GTCATGTGGTGCTCGTCTACCTGTATACGCACTGTTTGCTGCTGCATTCTTTCCTGGTGCTGGACAAAACGTTGTGTTCG
CTCTGTACATCATGGGTATTCTGGCTTCTGTATTTACGGGCTTGTTCCTTAAAAATACTACCTATCCTGGTAGCAGCGAT
AGCTTGGTTATGGAAATGCCGGATTACGAATTGCCGACCGTGCAAAACGTGATGCTGAAAACTTGGCAGAAGCTGAAACG
TTTCGTGCTTGGCGCAGGTAAAACCATTGTAATGGTTGTGGCAATTCTGAGTTTCTTGAATTCATTAGGTATGGACGGCA
GTTTTGGTAACGAAGACAGTGAAAGTTCTGTGCTATCTAAAGCGGCTCAAGTTGTAACTCCAGTGTTCCAACCGATTGGT
ATTACTGAAGAGAACTGGCCTGCAACGGTTGGTATCATTACCGGTATTTTTGCGAAAGAAGCCGTGGTTGGTACGCTAAA
TAGCTTATACACTACACCTTCTGATGAAGAAGCGGCTGAGTTTGATCTAGCGGCAAGTTTAGAAGAAGCCGTAATGACCA
TTCCTGAAAACCTTGCTGGTTTGAGCTATTCCGATCCATTAGGCATTGAAGTTGGTGACTTGTCTGACTCTAGTTCTGTG
GCTGCTGATCAAGAGGTTGATACTTCGATCTTTGGTAACTTGAAAGATAAGTTTGTATCAGGCCACGCTGCGTTTGCTTA
CTTAATCCTAATCTTGCTTTACACACCTTGTGTGGCAGCGATGGGTGCTTATGTTCGTGAATTTGGTCAGACGTTTGCCC
GCTTCATCGCAGTTTGGACAATGGCACTTGGTTACTTCGGTGCGACCTTCTATTACCAAGCAGCAAACTTCGCTGTACAC
CCAGTAAGTAGTGCTGTGTGGATGGTGGCAATAGCTGGTGGTTTTGTGATGACGTATCGCATCTTCAAGAAAATCGGCAG
TAAGCAAAAAGCACTTGAGGTGCAAGTAGTATGA

Upstream 100 bases:

>100_bases
TATCCGTCGTGCACCTATGGGTGATCCGCTTCAAGTTGAAGTGAGAGGTGTTTCTATAGCCATTCGTGAAAGCATTGCAG
AACAAATCGAGGTTATCTAA

Downstream 100 bases:

>100_bases
TTTTAACTGAACTTCATCAATACATTGATAACGAAGGTGTTGCTGCTCGTAGTGAGCTTGCATCTAAGTTTGGGGTAAGT
GAAGACGGTATCGATGCTAT

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 757

Protein sequence:

>757_residues
MDYQVLTVGNPNSGKTTLFNALTGAKQHVGNWVGVTVEKKTGLYSHAGDQFQLTDLPGIYALDSGNDANSIDESIASRAV
LTHPADVIINVVDASCLERSLYMTLQLRELGRPMIVVLNKMDVLKRERQVINLKALEKELGCPVLSLSANDKGQVVRFKE
RLHKLLVQGVSLDPISIDYDVALEALIPSVESQFDDADVSHRALAIRALENDYLVLNGLAPQTRTQIDSVRLGADFDIDL
AVADAKYTFLHELCKRVRRSEGKLSRNFTEKADQFILNKWVGIPFFFVIMYLMFMFSINIGSAFIDFFDIGVGAILVDGG
HHLLDGHLPVWLVTVLADGIGGGIQTVATFIPVIAALYLFLAVLESSGYMARAAFVLDKVMQKIGLPGKAFVPLVLGFGC
NVPSIMATRTLDQERERKLAASMAPFMSCGARLPVYALFAAAFFPGAGQNVVFALYIMGILASVFTGLFLKNTTYPGSSD
SLVMEMPDYELPTVQNVMLKTWQKLKRFVLGAGKTIVMVVAILSFLNSLGMDGSFGNEDSESSVLSKAAQVVTPVFQPIG
ITEENWPATVGIITGIFAKEAVVGTLNSLYTTPSDEEAAEFDLAASLEEAVMTIPENLAGLSYSDPLGIEVGDLSDSSSV
AADQEVDTSIFGNLKDKFVSGHAAFAYLILILLYTPCVAAMGAYVREFGQTFARFIAVWTMALGYFGATFYYQAANFAVH
PVSSAVWMVAIAGGFVMTYRIFKKIGSKQKALEVQVV

Sequences:

>Translated_757_residues
MDYQVLTVGNPNSGKTTLFNALTGAKQHVGNWVGVTVEKKTGLYSHAGDQFQLTDLPGIYALDSGNDANSIDESIASRAV
LTHPADVIINVVDASCLERSLYMTLQLRELGRPMIVVLNKMDVLKRERQVINLKALEKELGCPVLSLSANDKGQVVRFKE
RLHKLLVQGVSLDPISIDYDVALEALIPSVESQFDDADVSHRALAIRALENDYLVLNGLAPQTRTQIDSVRLGADFDIDL
AVADAKYTFLHELCKRVRRSEGKLSRNFTEKADQFILNKWVGIPFFFVIMYLMFMFSINIGSAFIDFFDIGVGAILVDGG
HHLLDGHLPVWLVTVLADGIGGGIQTVATFIPVIAALYLFLAVLESSGYMARAAFVLDKVMQKIGLPGKAFVPLVLGFGC
NVPSIMATRTLDQERERKLAASMAPFMSCGARLPVYALFAAAFFPGAGQNVVFALYIMGILASVFTGLFLKNTTYPGSSD
SLVMEMPDYELPTVQNVMLKTWQKLKRFVLGAGKTIVMVVAILSFLNSLGMDGSFGNEDSESSVLSKAAQVVTPVFQPIG
ITEENWPATVGIITGIFAKEAVVGTLNSLYTTPSDEEAAEFDLAASLEEAVMTIPENLAGLSYSDPLGIEVGDLSDSSSV
AADQEVDTSIFGNLKDKFVSGHAAFAYLILILLYTPCVAAMGAYVREFGQTFARFIAVWTMALGYFGATFYYQAANFAVH
PVSSAVWMVAIAGGFVMTYRIFKKIGSKQKALEVQVV
>Mature_757_residues
MDYQVLTVGNPNSGKTTLFNALTGAKQHVGNWVGVTVEKKTGLYSHAGDQFQLTDLPGIYALDSGNDANSIDESIASRAV
LTHPADVIINVVDASCLERSLYMTLQLRELGRPMIVVLNKMDVLKRERQVINLKALEKELGCPVLSLSANDKGQVVRFKE
RLHKLLVQGVSLDPISIDYDVALEALIPSVESQFDDADVSHRALAIRALENDYLVLNGLAPQTRTQIDSVRLGADFDIDL
AVADAKYTFLHELCKRVRRSEGKLSRNFTEKADQFILNKWVGIPFFFVIMYLMFMFSINIGSAFIDFFDIGVGAILVDGG
HHLLDGHLPVWLVTVLADGIGGGIQTVATFIPVIAALYLFLAVLESSGYMARAAFVLDKVMQKIGLPGKAFVPLVLGFGC
NVPSIMATRTLDQERERKLAASMAPFMSCGARLPVYALFAAAFFPGAGQNVVFALYIMGILASVFTGLFLKNTTYPGSSD
SLVMEMPDYELPTVQNVMLKTWQKLKRFVLGAGKTIVMVVAILSFLNSLGMDGSFGNEDSESSVLSKAAQVVTPVFQPIG
ITEENWPATVGIITGIFAKEAVVGTLNSLYTTPSDEEAAEFDLAASLEEAVMTIPENLAGLSYSDPLGIEVGDLSDSSSV
AADQEVDTSIFGNLKDKFVSGHAAFAYLILILLYTPCVAAMGAYVREFGQTFARFIAVWTMALGYFGATFYYQAANFAVH
PVSSAVWMVAIAGGFVMTYRIFKKIGSKQKALEVQVV

Specific function: Fe(2+) uptake system, probably driven by GTP [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the feoB (TC 9.A.8) family [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=742, Percent_Identity=44.4743935309973, Blast_Score=552, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate [H]

EC number: NA

Molecular weight: Translated: 82229; Mature: 82229

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYQVLTVGNPNSGKTTLFNALTGAKQHVGNWVGVTVEKKTGLYSHAGDQFQLTDLPGIY
CCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCCEE
ALDSGNDANSIDESIASRAVLTHPADVIINVVDASCLERSLYMTLQLRELGRPMIVVLNK
EECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
MDVLKRERQVINLKALEKELGCPVLSLSANDKGQVVRFKERLHKLLVQGVSLDPISIDYD
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
VALEALIPSVESQFDDADVSHRALAIRALENDYLVLNGLAPQTRTQIDSVRLGADFDIDL
HHHHHHHHHHHHCCCCCCCHHHHEEEEEECCCEEEEECCCCHHHHHHHHEEECCCCCEEE
AVADAKYTFLHELCKRVRRSEGKLSRNFTEKADQFILNKWVGIPFFFVIMYLMFMFSINI
EEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GSAFIDFFDIGVGAILVDGGHHLLDGHLPVWLVTVLADGIGGGIQTVATFIPVIAALYLF
HHHHHHHHHCCCCEEEEECCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LAVLESSGYMARAAFVLDKVMQKIGLPGKAFVPLVLGFGCNVPSIMATRTLDQERERKLA
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ASMAPFMSCGARLPVYALFAAAFFPGAGQNVVFALYIMGILASVFTGLFLKNTTYPGSSD
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SLVMEMPDYELPTVQNVMLKTWQKLKRFVLGAGKTIVMVVAILSFLNSLGMDGSFGNEDS
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
ESSVLSKAAQVVTPVFQPIGITEENWPATVGIITGIFAKEAVVGTLNSLYTTPSDEEAAE
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
FDLAASLEEAVMTIPENLAGLSYSDPLGIEVGDLSDSSSVAADQEVDTSIFGNLKDKFVS
HHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCHHHHHHC
GHAAFAYLILILLYTPCVAAMGAYVREFGQTFARFIAVWTMALGYFGATFYYQAANFAVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEC
PVSSAVWMVAIAGGFVMTYRIFKKIGSKQKALEVQVV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MDYQVLTVGNPNSGKTTLFNALTGAKQHVGNWVGVTVEKKTGLYSHAGDQFQLTDLPGIY
CCEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCCEE
ALDSGNDANSIDESIASRAVLTHPADVIINVVDASCLERSLYMTLQLRELGRPMIVVLNK
EECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHH
MDVLKRERQVINLKALEKELGCPVLSLSANDKGQVVRFKERLHKLLVQGVSLDPISIDYD
HHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHH
VALEALIPSVESQFDDADVSHRALAIRALENDYLVLNGLAPQTRTQIDSVRLGADFDIDL
HHHHHHHHHHHHCCCCCCCHHHHEEEEEECCCEEEEECCCCHHHHHHHHEEECCCCCEEE
AVADAKYTFLHELCKRVRRSEGKLSRNFTEKADQFILNKWVGIPFFFVIMYLMFMFSINI
EEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GSAFIDFFDIGVGAILVDGGHHLLDGHLPVWLVTVLADGIGGGIQTVATFIPVIAALYLF
HHHHHHHHHCCCCEEEEECCCEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LAVLESSGYMARAAFVLDKVMQKIGLPGKAFVPLVLGFGCNVPSIMATRTLDQERERKLA
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
ASMAPFMSCGARLPVYALFAAAFFPGAGQNVVFALYIMGILASVFTGLFLKNTTYPGSSD
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SLVMEMPDYELPTVQNVMLKTWQKLKRFVLGAGKTIVMVVAILSFLNSLGMDGSFGNEDS
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
ESSVLSKAAQVVTPVFQPIGITEENWPATVGIITGIFAKEAVVGTLNSLYTTPSDEEAAE
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
FDLAASLEEAVMTIPENLAGLSYSDPLGIEVGDLSDSSSVAADQEVDTSIFGNLKDKFVS
HHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCHHHHHHC
GHAAFAYLILILLYTPCVAAMGAYVREFGQTFARFIAVWTMALGYFGATFYYQAANFAVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEC
PVSSAVWMVAIAGGFVMTYRIFKKIGSKQKALEVQVV
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA