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The map label for this gene is siaT [H]

Identifier: 218710178

GI number: 218710178

Start: 2361032

End: 2362393

Strand: Reverse

Name: siaT [H]

Synonym: VS_2210

Alternate gene names: 218710178

Gene position: 2362393-2361032 (Counterclockwise)

Preceding gene: 218710179

Following gene: 218710175

Centisome position: 71.6

GC content: 47.94

Gene sequence:

>1362_bases
ATGGCAATGTTATTTCTATTTTTAATGGTAATTGCTTTCATGTTGGTCGGTGTACCAATTGCGATTTCCCTTGGTTTATC
GAGCGTTATATTCTTGTTGATGCACTCTGATGCGTCACTAGCTTCGGTTGCACAAACGTTGTTCAACGCATTTGCAGGCC
ACTACACACTCTTAGCGATCCCTTTCTTTATCTTGGCCTCTAGCTTCATGTCCACTGGGGGTGTGGCGAAACGTATTATC
CGTTTTGCTATCGCAATGGTCGGCTGGTTCCGCGGCGGTTTAGCGATGGCGTCGGTTGTGGCATGTATGATGTTCGCAGC
GTTATCTGGATCGTCTCCAGCAACGGTAGTGGCAATCGGTAGTATTGTTATCGCGGGTATGATCAAAAACGGCTACACAA
AAGAGTTCGCGGCAGGGGTTATCTGTAACGCGGGTACTTTGGGTATCTTGATTCCACCATCCATCGTTATGGTGGTTTAC
GCTGCGGCGACGGATGTATCTGTCGGTCGTATGTTCTTAGGCGGCGTGATTCCTGGTCTGTTGGCGGGTGTGATGTTGAT
GATAGCTATCTACATTGCAGCACGTATTAAGAAAATTCCTGCACAGCCATTTGTGGGCTGGGGTGAGATGTTCGCGGCCG
CGAAGGATGCGAGCTGGGGCTTGTTGCTGATTGTTATCATTTTAGGTGGTATCTACGGAGGTATCTTTACTCCGACAGAA
GCGGCGGCTGTTGCAGCGGTTTACGCGTTCTTCATTGCCAACTTTATCTACAAAGATATGGGGCCGTTTGCGGACAAGAA
AAATACGAAGCCTGCTTTGGTGAAAGTGTTCCAAACGTTTTTCCATAAAGACACCAAAGACACGCTCTATGATGCGGGTA
AGCTGACCATCATGTTGTTGTTTATCATTGCCAATGCTCTGATTCTTAAGCATGTACTGACAGAGGAGCGCATTCCTCAG
ATGATCACGGAATCCATGTTGTCTGCAGGTTTAGGGCCGATCACCTTCTTGATTGTGGTGAACGTTCTACTCTTGATTGG
TGGGCAGTTCATGGAGCCATCAGGCTTGCTGATCATCGTTGCGCCGTTGGTATTCCCTATTGCAATTGCACTGGGCATCG
ACCCAATTCACCTAGGTATCATGATGGTGGTGAACATGGAGATAGGGATGATAACGCCGCCTGTTGGGCTTAATTTGTTT
GTGACTGCCGGGGTTGCCAAGATGTCGATGATGAACGTGGTAAAAGCAGCGTTGCCGTGGGTTGGCGTGATGTTCTTGTT
CTTGATTATCGTAACTTACGTACCTTGGGTATCAACATGGTTACCGACTACCTTGATGGGGCCTGAGATCATCACTAAGT
AG

Upstream 100 bases:

>100_bases
TAGCGGGTTCTGATGAAGACGCGACAGCGGTATTGGATTCGACTAAGCAAAACAAGGCGAACGAGTCGGGTACAAAATCT
AACGGTAAGGAAGACTAATC

Downstream 100 bases:

>100_bases
ATAGTGAAGTAACAACGAAGTGATGAGGAGGGTTAAACCTCCTCATCGATAATCTTGCCATATCTAGAACCTGAATCAAT
CTGCTCATACAGCGCTCTTT

Product: C4-dicarboxylate transport system permease DctQ

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MAMLFLFLMVIAFMLVGVPIAISLGLSSVIFLLMHSDASLASVAQTLFNAFAGHYTLLAIPFFILASSFMSTGGVAKRII
RFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIGSIVIAGMIKNGYTKEFAAGVICNAGTLGILIPPSIVMVVY
AAATDVSVGRMFLGGVIPGLLAGVMLMIAIYIAARIKKIPAQPFVGWGEMFAAAKDASWGLLLIVIILGGIYGGIFTPTE
AAAVAAVYAFFIANFIYKDMGPFADKKNTKPALVKVFQTFFHKDTKDTLYDAGKLTIMLLFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIVAPLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLF
VTAGVAKMSMMNVVKAALPWVGVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK

Sequences:

>Translated_453_residues
MAMLFLFLMVIAFMLVGVPIAISLGLSSVIFLLMHSDASLASVAQTLFNAFAGHYTLLAIPFFILASSFMSTGGVAKRII
RFAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIGSIVIAGMIKNGYTKEFAAGVICNAGTLGILIPPSIVMVVY
AAATDVSVGRMFLGGVIPGLLAGVMLMIAIYIAARIKKIPAQPFVGWGEMFAAAKDASWGLLLIVIILGGIYGGIFTPTE
AAAVAAVYAFFIANFIYKDMGPFADKKNTKPALVKVFQTFFHKDTKDTLYDAGKLTIMLLFIIANALILKHVLTEERIPQ
MITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIVAPLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLF
VTAGVAKMSMMNVVKAALPWVGVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK
>Mature_452_residues
AMLFLFLMVIAFMLVGVPIAISLGLSSVIFLLMHSDASLASVAQTLFNAFAGHYTLLAIPFFILASSFMSTGGVAKRIIR
FAIAMVGWFRGGLAMASVVACMMFAALSGSSPATVVAIGSIVIAGMIKNGYTKEFAAGVICNAGTLGILIPPSIVMVVYA
AATDVSVGRMFLGGVIPGLLAGVMLMIAIYIAARIKKIPAQPFVGWGEMFAAAKDASWGLLLIVIILGGIYGGIFTPTEA
AAVAAVYAFFIANFIYKDMGPFADKKNTKPALVKVFQTFFHKDTKDTLYDAGKLTIMLLFIIANALILKHVLTEERIPQM
ITESMLSAGLGPITFLIVVNVLLLIGGQFMEPSGLLIIVAPLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLFV
TAGVAKMSMMNVVKAALPWVGVMFLFLIIVTYVPWVSTWLPTTLMGPEIITK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=419, Percent_Identity=33.890214797136, Blast_Score=205, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 48131; Mature: 48000

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCC
>Mature Secondary Structure 
AMLFLFLMVIAFMLVGVPIAISLGLSSVIFLLMHSDASLASVAQTLFNAFAGHYTLLAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]