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The map label for this gene is azlC [H]

Identifier: 218710136

GI number: 218710136

Start: 2311626

End: 2312375

Strand: Reverse

Name: azlC [H]

Synonym: VS_2157

Alternate gene names: 218710136

Gene position: 2312375-2311626 (Counterclockwise)

Preceding gene: 218710137

Following gene: 218710135

Centisome position: 70.09

GC content: 47.2

Gene sequence:

>750_bases
GTGAAGAGAGAAAAGAACTATATGGATAGTGAAACAATGGATAGACGAACACAGTTATGGAAGGGCGTTTTAGCGGGAAT
GCCCTTGAGCATTGCGGTAATCCCTTGGGGAATTCTAGCGGGCTCATATGCGATAGATGCAGGATTGAGTCAGCTTCAAG
CGCAAGCGATGTCGGCTATTCTATTTGCTGGCTCAGCACAACTTGTCGCCGCGGGTATGTTCAAAGCGGGTATTGGTCTA
GGCACCATGTTGTTGACTACCTTATTCATCACGTCTAGACACTTCTTATACAGCGTATCGATGCGTGACAAAATCAGCCA
CCTTCCTGCTCGTTGGCGTTTATTGCTTGGCTTTTGGCTGACGGATGAACTGTTCGCGATTTGTAGTGGCCAATCTCAGC
AAGAGTTTAACCACTGGTATGCAGCAGGGGTCGGCGGTGGTTTTTATCTTGTTTGGAATATTGCGAGTTTTGTCGGCATT
GTCGCAGGTAGTCAAATCCCATCACTTAACGAGATTGGGCTCGATTTCGCGGTCGCAGCAACCTTTATTGCGTTAGTTTT
TCCATTAATCAGAACATTGCCTGTTGTCGTATGTGTGGTGGTTTCATTGGTCACATCGGTTGCCATGTCGGTTAACAATA
TTGAGGGCGGGCTAATGATTGCAGCGATTGCCGGTATGTTAGCGGGCTTTATCAGCGAATCGTTCCAAGAGCGAAACAAC
GGCAACAAGACAATTGTGGAAGGGGAATAG

Upstream 100 bases:

>100_bases
TCGTGTTAAGTTCGGTTAAGTGTGGCAAACAGAGGGACATGAAATCGAGCAAATTTGTACAATCGAACCGACTCAACTCC
TCTTACATTGAATAGCCAAT

Downstream 100 bases:

>100_bases
AGATGATCTGGTTAACGATATTACTTATGACGGCGATTGTTTTCTTTAGCCGCTATCTGTTTCTAGAGCCTGCTATCCCG
CTACGACTCAATCAAACCGC

Product: AzlC family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKREKNYMDSETMDRRTQLWKGVLAGMPLSIAVIPWGILAGSYAIDAGLSQLQAQAMSAILFAGSAQLVAAGMFKAGIGL
GTMLLTTLFITSRHFLYSVSMRDKISHLPARWRLLLGFWLTDELFAICSGQSQQEFNHWYAAGVGGGFYLVWNIASFVGI
VAGSQIPSLNEIGLDFAVAATFIALVFPLIRTLPVVVCVVVSLVTSVAMSVNNIEGGLMIAAIAGMLAGFISESFQERNN
GNKTIVEGE

Sequences:

>Translated_249_residues
MKREKNYMDSETMDRRTQLWKGVLAGMPLSIAVIPWGILAGSYAIDAGLSQLQAQAMSAILFAGSAQLVAAGMFKAGIGL
GTMLLTTLFITSRHFLYSVSMRDKISHLPARWRLLLGFWLTDELFAICSGQSQQEFNHWYAAGVGGGFYLVWNIASFVGI
VAGSQIPSLNEIGLDFAVAATFIALVFPLIRTLPVVVCVVVSLVTSVAMSVNNIEGGLMIAAIAGMLAGFISESFQERNN
GNKTIVEGE
>Mature_249_residues
MKREKNYMDSETMDRRTQLWKGVLAGMPLSIAVIPWGILAGSYAIDAGLSQLQAQAMSAILFAGSAQLVAAGMFKAGIGL
GTMLLTTLFITSRHFLYSVSMRDKISHLPARWRLLLGFWLTDELFAICSGQSQQEFNHWYAAGVGGGFYLVWNIASFVGI
VAGSQIPSLNEIGLDFAVAATFIALVFPLIRTLPVVVCVVVSLVTSVAMSVNNIEGGLMIAAIAGMLAGFISESFQERNN
GNKTIVEGE

Specific function: Involved in branched-chain amino acid transport [H]

COG id: COG1296

COG function: function code E; Predicted branched-chain amino acid permease (azaleucine resistance)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AzlC family [H]

Homologues:

Organism=Escherichia coli, GI1789038, Length=225, Percent_Identity=26.6666666666667, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004471
- InterPro:   IPR011606 [H]

Pfam domain/function: PF03591 AzlC [H]

EC number: NA

Molecular weight: Translated: 26805; Mature: 26805

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEEEECC
>Mature Secondary Structure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CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]