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The map label for this gene is hlyB [H]

Identifier: 218710060

GI number: 218710060

Start: 2232326

End: 2234317

Strand: Direct

Name: hlyB [H]

Synonym: VS_2080

Alternate gene names: 218710060

Gene position: 2232326-2234317 (Clockwise)

Preceding gene: 218710051

Following gene: 218710061

Centisome position: 67.66

GC content: 44.13

Gene sequence:

>1992_bases
ATGAAGGGATCTGTGATCAAGCGTATGTACGCTGGTTTCGCACTGATCATCATCATGTTCGCAGTCACGATAACCATCAT
GATGAGCAGCATGAATCAGATACATAGCAATTTTGAGAGCGTCTCAAAAGTCTCATTGCCGCTGGTTGCGCTTTCAAACC
AAACAAGTGTCCAATTACTTTCCGCTGACAAGTCATTTAAAGACTTCTTAACCACACAAAATTCTGAGCGTATGTCTGCA
ATGCGTACAGAGTTTGCTGCATCACAAAACGCTTTTTCTGAAGTTCTAGGTAGCCTAGAAACAGCAAGCCAAGACAATAC
CTCACTCACTGAGCGCATCACGCAATTAAGAGCAATGGAAGAACGTTACTTCACCGAAGCAGATGAAGCGATGAACAACT
ACATAGCTATGTTTGAGGCGCAAGAGCAAGTACAAAAAGCATCACGTGATTTCCAACGCTTACATTCAGAATTGACCGTT
GGCATGAAAGAGTACGTTGCCGACCAAAAAAGCATCTCTGTAAAAGTGATGGCAAAGAGCTACTTTATTAAACTACAAGA
CGCGGAGGTGATTACCTCTGATGCACTAGCAAGTTCTGATGTTGCCTTCGTACAAAAAGCCGTTAACCAAAACAAAAAGG
CCGTTACCCACCTAAACTACGCGTACCGTGGTTTAGCGACACAATTGCCTGCGATAAAAAATGTTTTCGATGAATCGGTT
AAAAACTTCACCAAAGACGTGGGACAAAAAGGCGGTGTTTTAGATAAACATAATAACTATCTGAAAGCGAAAGAAGCCTT
GTACATCAACATTGCTAATCTAGCCGTTGAAGTCGACCAAGCAATGGCGGTACTGGATTCTTTCAACGTCACAGCGGAAG
AGCAACTCAACTCATCATTAGCAGATGCGAGCAGCATCTACGACAACGGTCTATTCAAAGCGATTGCAATTGGCATTGTT
GTCACCGTATTCGCTGCAGCAATTGGTTACCACATTGCACATAGTGTAAGAGAGCCACTAACGCGTATCCTAGGTACATT
AGAAGGCCTGACTGAAGGAGATATGACTCAGCGTATCGATATTCGATACGACAACGAATTCAGCCGAGTAAGCCGTCACA
TCAATACCTTAGCCGACAACCTGCACAATATTCTGGTGAAACTGAATGACGCTTCAGATGACCTAACCAATACTGCAAGC
GTAAACCAAAAAACCTCTTCTGAGACACAGGCTCAATTGAACAGCCAGCGTGAACAAACAGCAACCGTCGCAACGGCAAT
GACACAAATGTCTCACTCTGTACAAGAAGTAGCAAACAGCGCGCAAAGCTCGTTAACTATGGTTCAACAAGTAGAATCGG
CTTCTGAATCAGGTCGTCAGGTCATGAACACCAACATCAGTACCATCAATCAACTTGAGGTGCGCCTGACTGAATCCGTG
GGTGCTGTAGGCGAGCTACAACAAATGAGTAGCCAGATTGGCTCTATCCTCGATGTTATTCGTGGTATTGCAGATCAAAC
CAACCTACTTGCACTCAACGCAGCAATCGAAGCCGCGCGCGCAGGTGAACAAGGCCGTGGATTTGCTGTAGTTGCAGATG
AAGTCCGAGTACTGGCACAAAAGACAACTCAATCGACGTCTGAAATTGAGACCATGATCAGTAACCTACAATCAAGTTCT
AAAACAGCAAGCAATGTGATTGAAAGCTGCATGAGCGATATGGATATGTCGGTTCAACAAGCTTCAAGTGCTAATAGTGC
TATGGAAGAAATTCAGGCATTGATTCTAGAAATCAGTCGAATGAGTACGCACATTTCTCAAGCCGCGGCTGAGCAGAGTG
AAACTTCGGGTGATATCGCGCGTAACATTGAAGACATCAACCAGATTGCTGATAAGAGTTATCAAGCGATGTCATCAATT
GCAGAGGCAAGCCAAAACCTAACAATTCTGGCAAACCAGCAAGGCGATTTAGTTCATCAATTCAAGCTATAA

Upstream 100 bases:

>100_bases
GCGTCATAAAATGCGTAAGCCGAGCTCAATAGAATCCTGATAATTTTGTTAGTTTTGTTTTGACCTGGTATTAGGTCCAC
ATTTATTTAGGGAGAAAGTC

Downstream 100 bases:

>100_bases
GTAAACGAAGAACCAATAGATATTCACCTGAAATGTTGGGATATCTCACCCAATAGTGATAACTAATTGAACAAGGGCAA
CTTTTATCAAGGGTTGCCCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MKGSVIKRMYAGFALIIIMFAVTITIMMSSMNQIHSNFESVSKVSLPLVALSNQTSVQLLSADKSFKDFLTTQNSERMSA
MRTEFAASQNAFSEVLGSLETASQDNTSLTERITQLRAMEERYFTEADEAMNNYIAMFEAQEQVQKASRDFQRLHSELTV
GMKEYVADQKSISVKVMAKSYFIKLQDAEVITSDALASSDVAFVQKAVNQNKKAVTHLNYAYRGLATQLPAIKNVFDESV
KNFTKDVGQKGGVLDKHNNYLKAKEALYINIANLAVEVDQAMAVLDSFNVTAEEQLNSSLADASSIYDNGLFKAIAIGIV
VTVFAAAIGYHIAHSVREPLTRILGTLEGLTEGDMTQRIDIRYDNEFSRVSRHINTLADNLHNILVKLNDASDDLTNTAS
VNQKTSSETQAQLNSQREQTATVATAMTQMSHSVQEVANSAQSSLTMVQQVESASESGRQVMNTNISTINQLEVRLTESV
GAVGELQQMSSQIGSILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQKTTQSTSEIETMISNLQSSS
KTASNVIESCMSDMDMSVQQASSANSAMEEIQALILEISRMSTHISQAAAEQSETSGDIARNIEDINQIADKSYQAMSSI
AEASQNLTILANQQGDLVHQFKL

Sequences:

>Translated_663_residues
MKGSVIKRMYAGFALIIIMFAVTITIMMSSMNQIHSNFESVSKVSLPLVALSNQTSVQLLSADKSFKDFLTTQNSERMSA
MRTEFAASQNAFSEVLGSLETASQDNTSLTERITQLRAMEERYFTEADEAMNNYIAMFEAQEQVQKASRDFQRLHSELTV
GMKEYVADQKSISVKVMAKSYFIKLQDAEVITSDALASSDVAFVQKAVNQNKKAVTHLNYAYRGLATQLPAIKNVFDESV
KNFTKDVGQKGGVLDKHNNYLKAKEALYINIANLAVEVDQAMAVLDSFNVTAEEQLNSSLADASSIYDNGLFKAIAIGIV
VTVFAAAIGYHIAHSVREPLTRILGTLEGLTEGDMTQRIDIRYDNEFSRVSRHINTLADNLHNILVKLNDASDDLTNTAS
VNQKTSSETQAQLNSQREQTATVATAMTQMSHSVQEVANSAQSSLTMVQQVESASESGRQVMNTNISTINQLEVRLTESV
GAVGELQQMSSQIGSILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQKTTQSTSEIETMISNLQSSS
KTASNVIESCMSDMDMSVQQASSANSAMEEIQALILEISRMSTHISQAAAEQSETSGDIARNIEDINQIADKSYQAMSSI
AEASQNLTILANQQGDLVHQFKL
>Mature_663_residues
MKGSVIKRMYAGFALIIIMFAVTITIMMSSMNQIHSNFESVSKVSLPLVALSNQTSVQLLSADKSFKDFLTTQNSERMSA
MRTEFAASQNAFSEVLGSLETASQDNTSLTERITQLRAMEERYFTEADEAMNNYIAMFEAQEQVQKASRDFQRLHSELTV
GMKEYVADQKSISVKVMAKSYFIKLQDAEVITSDALASSDVAFVQKAVNQNKKAVTHLNYAYRGLATQLPAIKNVFDESV
KNFTKDVGQKGGVLDKHNNYLKAKEALYINIANLAVEVDQAMAVLDSFNVTAEEQLNSSLADASSIYDNGLFKAIAIGIV
VTVFAAAIGYHIAHSVREPLTRILGTLEGLTEGDMTQRIDIRYDNEFSRVSRHINTLADNLHNILVKLNDASDDLTNTAS
VNQKTSSETQAQLNSQREQTATVATAMTQMSHSVQEVANSAQSSLTMVQQVESASESGRQVMNTNISTINQLEVRLTESV
GAVGELQQMSSQIGSILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQKTTQSTSEIETMISNLQSSS
KTASNVIESCMSDMDMSVQQASSANSAMEEIQALILEISRMSTHISQAAAEQSETSGDIARNIEDINQIADKSYQAMSSI
AEASQNLTILANQQGDLVHQFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=318, Percent_Identity=30.188679245283, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1787690, Length=309, Percent_Identity=31.7152103559871, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1788195, Length=286, Percent_Identity=30.0699300699301, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=301, Percent_Identity=27.906976744186, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789453, Length=266, Percent_Identity=31.5789473684211, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72341; Mature: 72341

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSVIKRMYAGFALIIIMFAVTITIMMSSMNQIHSNFESVSKVSLPLVALSNQTSVQLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEE
SADKSFKDFLTTQNSERMSAMRTEFAASQNAFSEVLGSLETASQDNTSLTERITQLRAME
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ERYFTEADEAMNNYIAMFEAQEQVQKASRDFQRLHSELTVGMKEYVADQKSISVKVMAKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEH
YFIKLQDAEVITSDALASSDVAFVQKAVNQNKKAVTHLNYAYRGLATQLPAIKNVFDESV
HEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNFTKDVGQKGGVLDKHNNYLKAKEALYINIANLAVEVDQAMAVLDSFNVTAEEQLNSSL
HHHHHHHCCCCCCCCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ADASSIYDNGLFKAIAIGIVVTVFAAAIGYHIAHSVREPLTRILGTLEGLTEGDMTQRID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
IRYDNEFSRVSRHINTLADNLHNILVKLNDASDDLTNTASVNQKTSSETQAQLNSQREQT
EEECCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ATVATAMTQMSHSVQEVANSAQSSLTMVQQVESASESGRQVMNTNISTINQLEVRLTESV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHH
GAVGELQQMSSQIGSILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
KTTQSTSEIETMISNLQSSSKTASNVIESCMSDMDMSVQQASSANSAMEEIQALILEISR
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
MSTHISQAAAEQSETSGDIARNIEDINQIADKSYQAMSSIAEASQNLTILANQQGDLVHQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
FKL
CCC
>Mature Secondary Structure
MKGSVIKRMYAGFALIIIMFAVTITIMMSSMNQIHSNFESVSKVSLPLVALSNQTSVQLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCEEEE
SADKSFKDFLTTQNSERMSAMRTEFAASQNAFSEVLGSLETASQDNTSLTERITQLRAME
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
ERYFTEADEAMNNYIAMFEAQEQVQKASRDFQRLHSELTVGMKEYVADQKSISVKVMAKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEH
YFIKLQDAEVITSDALASSDVAFVQKAVNQNKKAVTHLNYAYRGLATQLPAIKNVFDESV
HEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KNFTKDVGQKGGVLDKHNNYLKAKEALYINIANLAVEVDQAMAVLDSFNVTAEEQLNSSL
HHHHHHHCCCCCCCCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ADASSIYDNGLFKAIAIGIVVTVFAAAIGYHIAHSVREPLTRILGTLEGLTEGDMTQRID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
IRYDNEFSRVSRHINTLADNLHNILVKLNDASDDLTNTASVNQKTSSETQAQLNSQREQT
EEECCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ATVATAMTQMSHSVQEVANSAQSSLTMVQQVESASESGRQVMNTNISTINQLEVRLTESV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHHHHHHHH
GAVGELQQMSSQIGSILDVIRGIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLAQ
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCEEEEHHHHHHHHH
KTTQSTSEIETMISNLQSSSKTASNVIESCMSDMDMSVQQASSANSAMEEIQALILEISR
HHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
MSTHISQAAAEQSETSGDIARNIEDINQIADKSYQAMSSIAEASQNLTILANQQGDLVHQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
FKL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]