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The map label for this gene is htpX [H]

Identifier: 218710015

GI number: 218710015

Start: 2181636

End: 2182499

Strand: Reverse

Name: htpX [H]

Synonym: VS_2035

Alternate gene names: 218710015

Gene position: 2182499-2181636 (Counterclockwise)

Preceding gene: 218710017

Following gene: 218710011

Centisome position: 66.15

GC content: 46.3

Gene sequence:

>864_bases
ATGAAGCGAGTAATGTTGTTCCTTGCAACCAACCTAGCGGTTGTATTGGTACTAAGTGTTGTTCTTAATATTGTATACGC
AGTTACAGGTATGCAACCTGGTAGCCTATCAGGCTTATTGGTGATGGCTGCAGTATTTGGCTTTGGTGGCTCATTCATTT
CATTGATGATGTCAAAGAAAATGGCGCTACGATCGGTAGGCGGTATGGTCATTGAAAGTCCACGTAACGAAACCGAACAT
TGGTTGATGGAGACAGTAAGCCGTCAGTCTCAACAAGTTGGTATTGGTATGCCAACGGTGGCGATTTACGATTCGCCAGA
CATCAACGCGTTTGCGACGGGCGCTAAGCGTAATGATTCATTAGTAGCAGTCTCTACGGGTCTGCTACACAACATGACGC
GTGATGAAGCTGAAGCAGTGTTAGCGCATGAAGTGAGTCACATCGCGAACGGTGATATGGTGACCATGACGCTAATGCAG
GGCGTGGTGAACACGTTCGTTATCTTCCTATCTCGTTTCATCGCCAACATTGTTGCGTCGAATGACAACGAAGAAGAGGG
TGGCAGCAACATGATGGTGTACTTTGGTGTGTCTATGGTGTTGGAATTGGTATTTGGTTTCTTAGCAAGCTTCATTACGA
TGTGGTACAGCCGTCATCGTGAATTCCATGCCGATGCAGATGCTGCGCACTTAGTAGGTAAAGAGAAGATGATAGCAGCG
CTAGAACGTCTAAAGGTGAGCCATGAGCCACAACTAGAAGGTTCTATGATGGCATTTGGTATCAACGGCAAGAAATCGCT
TACTGAGCTTCTGATGAGCCACCCACCACTAGACAAGCGTATTGCATCTCTACGTAACATGTAA

Upstream 100 bases:

>100_bases
ATATGTATAAGTAAGTATAAGTCTTCAAGGTTGGAATAAATTGCTGTCTGCCTTGTCTATAATAAGTTTTATAAAAACAG
CTTTCATGCGGAGATAAGTA

Downstream 100 bases:

>100_bases
TCGCTACGTAATTCTCAGTCGCTAGTCGACAAGAGACCTTTGAAAGGCTTCCTTCGGGAGGCCTTTTTTGATCTTGGTGT
TCAAGACAGTAAGTATCCGA

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKRVMLFLATNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGSFISLMMSKKMALRSVGGMVIESPRNETEH
WLMETVSRQSQQVGIGMPTVAIYDSPDINAFATGAKRNDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQ
GVVNTFVIFLSRFIANIVASNDNEEEGGSNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADADAAHLVGKEKMIAA
LERLKVSHEPQLEGSMMAFGINGKKSLTELLMSHPPLDKRIASLRNM

Sequences:

>Translated_287_residues
MKRVMLFLATNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGSFISLMMSKKMALRSVGGMVIESPRNETEH
WLMETVSRQSQQVGIGMPTVAIYDSPDINAFATGAKRNDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQ
GVVNTFVIFLSRFIANIVASNDNEEEGGSNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADADAAHLVGKEKMIAA
LERLKVSHEPQLEGSMMAFGINGKKSLTELLMSHPPLDKRIASLRNM
>Mature_287_residues
MKRVMLFLATNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGSFISLMMSKKMALRSVGGMVIESPRNETEH
WLMETVSRQSQQVGIGMPTVAIYDSPDINAFATGAKRNDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQ
GVVNTFVIFLSRFIANIVASNDNEEEGGSNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADADAAHLVGKEKMIAA
LERLKVSHEPQLEGSMMAFGINGKKSLTELLMSHPPLDKRIASLRNM

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=292, Percent_Identity=66.7808219178082, Blast_Score=391, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31336; Mature: 31336

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
8.0 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.0 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVMLFLATNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGSFISLMMSKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
MALRSVGGMVIESPRNETEHWLMETVSRQSQQVGIGMPTVAIYDSPDINAFATGAKRNDS
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCCCC
LVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANIVAS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NDNEEEGGSNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADADAAHLVGKEKMIAA
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LERLKVSHEPQLEGSMMAFGINGKKSLTELLMSHPPLDKRIASLRNM
HHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRVMLFLATNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGSFISLMMSKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
MALRSVGGMVIESPRNETEHWLMETVSRQSQQVGIGMPTVAIYDSPDINAFATGAKRNDS
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCCCC
LVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANIVAS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NDNEEEGGSNMMVYFGVSMVLELVFGFLASFITMWYSRHREFHADADAAHLVGKEKMIAA
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LERLKVSHEPQLEGSMMAFGINGKKSLTELLMSHPPLDKRIASLRNM
HHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA