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The map label for this gene is nrfD [H]

Identifier: 218709917

GI number: 218709917

Start: 2073215

End: 2074195

Strand: Reverse

Name: nrfD [H]

Synonym: VS_1930

Alternate gene names: 218709917

Gene position: 2074195-2073215 (Counterclockwise)

Preceding gene: 218709918

Following gene: 218709916

Centisome position: 62.87

GC content: 43.63

Gene sequence:

>981_bases
TTGATTATGAGTGCATGGGACGCAGCTTTTCAGTCTGGTACCGTGGTATGGGACTGGATTATAGCAATCTATCTATTTCT
CGCGGGGATGTCGGCGGGTGCCGTAATGATCTCCATTTACCTTAAGCGCAAGGTTATTGAAGGCGATCCTGCTCATAATG
GTGTGTTAAAGGCGACAGCTTTTCTTGCGCCATTTGGGATCATTTCAGGCCTGCTGATCTTGGTTTTCCATCTGACAAAA
CCACTGTCATTTTGGAAGATCATGATCTTCTATAATCCAACGTCTGTGATGTCGATGGGTGTGATCTTATTCCAAGTGTA
TATGGTGATCTTATTCCTTTGGATCGGCATTATATTTAGAGATCAAATAGTCGTGTTCTTGAATGATCAAGCATGGCTAA
AAGGGCGACTTGATTTTGTCGGTAATTGGATTGGCAAATTAGAAGTGTTTGAGAATGCTCTGGAAATATTCTTAGCTGTT
CTTGCTCTTATGCTTGCCGCTTATACCGGATTCTTGCTTTCAGCTTTAAATACTTTCCCACTATTGAATAACCCAGTACT
GCCGATTTTATTCTTGTTCTCGAGTTTATCTTCGGGTGCGGCGGCGTGTATTTTATTCGGTGTGCTGGTCTTTAAAGAAT
CACCTCATAGCCCGACTATTTCATGGATCCACGGATTTGAACGCCCGGTAGTGATGTTTGAGTTGTTTGTTCTTATCACT
TTCTTTACTGGGTTGATCTTCGCTGGTGGTCAAAGTGAACAAGCAGTATGGAACGCAATTGGCAGTGGTTTCTGGGCGAG
TTGGTTCTGGTATGGCGTCATCGGTGTCGGTATGGTTTTACCGTTGTTGTTGAATGCCGTGACACCAACCTCAATCCGCC
ATAGCTCGGTGTATATTTTCTCCGTGACTTCGCTAAGCCTTATGGGCGTATTAATGCTGCGAACTTTTGTCCTTTATGCA
GGGCAGTTAACGATAGCTTAA

Upstream 100 bases:

>100_bases
AGATAAACCAAGTACTTCAATCCGAGGTGGTTTACAGAGATAAAGCCTATCTAGGCACCCAACCAAAACTCTATAAAGTG
CCACACCAAAAAGGGGAGAT

Downstream 100 bases:

>100_bases
TTTCGCGCAAGTTTATTAGTGAGCAGATGTCGGATACTAAACATCTGCTTATTAATGAACATGCTTTTAGTAAACATGAG
ATGCGTGTTCAGATCGGCTC

Product: hypothetical protein

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIMSAWDAAFQSGTVVWDWIIAIYLFLAGMSAGAVMISIYLKRKVIEGDPAHNGVLKATAFLAPFGIISGLLILVFHLTK
PLSFWKIMIFYNPTSVMSMGVILFQVYMVILFLWIGIIFRDQIVVFLNDQAWLKGRLDFVGNWIGKLEVFENALEIFLAV
LALMLAAYTGFLLSALNTFPLLNNPVLPILFLFSSLSSGAAACILFGVLVFKESPHSPTISWIHGFERPVVMFELFVLIT
FFTGLIFAGGQSEQAVWNAIGSGFWASWFWYGVIGVGMVLPLLLNAVTPTSIRHSSVYIFSVTSLSLMGVLMLRTFVLYA
GQLTIA

Sequences:

>Translated_326_residues
MIMSAWDAAFQSGTVVWDWIIAIYLFLAGMSAGAVMISIYLKRKVIEGDPAHNGVLKATAFLAPFGIISGLLILVFHLTK
PLSFWKIMIFYNPTSVMSMGVILFQVYMVILFLWIGIIFRDQIVVFLNDQAWLKGRLDFVGNWIGKLEVFENALEIFLAV
LALMLAAYTGFLLSALNTFPLLNNPVLPILFLFSSLSSGAAACILFGVLVFKESPHSPTISWIHGFERPVVMFELFVLIT
FFTGLIFAGGQSEQAVWNAIGSGFWASWFWYGVIGVGMVLPLLLNAVTPTSIRHSSVYIFSVTSLSLMGVLMLRTFVLYA
GQLTIA
>Mature_326_residues
MIMSAWDAAFQSGTVVWDWIIAIYLFLAGMSAGAVMISIYLKRKVIEGDPAHNGVLKATAFLAPFGIISGLLILVFHLTK
PLSFWKIMIFYNPTSVMSMGVILFQVYMVILFLWIGIIFRDQIVVFLNDQAWLKGRLDFVGNWIGKLEVFENALEIFLAV
LALMLAAYTGFLLSALNTFPLLNNPVLPILFLFSSLSSGAAACILFGVLVFKESPHSPTISWIHGFERPVVMFELFVLIT
FFTGLIFAGGQSEQAVWNAIGSGFWASWFWYGVIGVGMVLPLLLNAVTPTSIRHSSVYIFSVTSLSLMGVLMLRTFVLYA
GQLTIA

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG3301

COG function: function code P; Formate-dependent nitrite reductase, membrane component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nrfD family [H]

Homologues:

Organism=Escherichia coli, GI1790509, Length=321, Percent_Identity=46.7289719626168, Blast_Score=269, Evalue=2e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017566
- InterPro:   IPR005614 [H]

Pfam domain/function: PF03916 NrfD [H]

EC number: NA

Molecular weight: Translated: 36111; Mature: 36111

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMSAWDAAFQSGTVVWDWIIAIYLFLAGMSAGAVMISIYLKRKVIEGDPAHNGVLKATA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLAPFGIISGLLILVFHLTKPLSFWKIMIFYNPTSVMSMGVILFQVYMVILFLWIGIIFR
HHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQIVVFLNDQAWLKGRLDFVGNWIGKLEVFENALEIFLAVLALMLAAYTGFLLSALNTFP
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLNNPVLPILFLFSSLSSGAAACILFGVLVFKESPHSPTISWIHGFERPVVMFELFVLIT
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
FFTGLIFAGGQSEQAVWNAIGSGFWASWFWYGVIGVGMVLPLLLNAVTPTSIRHSSVYIF
HHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SVTSLSLMGVLMLRTFVLYAGQLTIA
EHHHHHHHHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MIMSAWDAAFQSGTVVWDWIIAIYLFLAGMSAGAVMISIYLKRKVIEGDPAHNGVLKATA
CCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHH
FLAPFGIISGLLILVFHLTKPLSFWKIMIFYNPTSVMSMGVILFQVYMVILFLWIGIIFR
HHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQIVVFLNDQAWLKGRLDFVGNWIGKLEVFENALEIFLAVLALMLAAYTGFLLSALNTFP
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLNNPVLPILFLFSSLSSGAAACILFGVLVFKESPHSPTISWIHGFERPVVMFELFVLIT
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
FFTGLIFAGGQSEQAVWNAIGSGFWASWFWYGVIGVGMVLPLLLNAVTPTSIRHSSVYIF
HHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SVTSLSLMGVLMLRTFVLYAGQLTIA
EHHHHHHHHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8057835; 8265357; 9278503 [H]