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The map label for this gene is aspC [H]

Identifier: 218709807

GI number: 218709807

Start: 1957897

End: 1959087

Strand: Direct

Name: aspC [H]

Synonym: VS_1819

Alternate gene names: 218709807

Gene position: 1957897-1959087 (Clockwise)

Preceding gene: 218709804

Following gene: 218709809

Centisome position: 59.34

GC content: 46.68

Gene sequence:

>1191_bases
ATGTTTGAAAAAGTGTTAGCAGCTCCCGCCGATCCTATTCTCGGCCTTACTGAAGAATTTAAAAAAGACTCTCGTGAAGA
GAAAATTAACCTTGGTGTTGGCATCTACAAAAATGAAGATGGTCAAACGCCAGTACTTAAAACAGTAAAGAAAGCAGAAG
CTGCACTTCTTGAAAACGAAAAAACCAAATCTTACCTAACGATTGAAGGTACCGCTGAATACGGTCTAGCGGTTCAGAAA
CTGCTTTTCGGTTCAGATGCAGAGATCGTAACGTCTCAACGCGCTAAAACAGCACAAGCTCCAGGTGGTACAGGTGCACT
TCGCGTAGCGGGTGAATTCATCAAGCGCCAACTGGGTGACGTGAAAATCTGGATCAGTAACCCAACTTGGGCTAACCACA
ACGGCGTTTTCGCTGCTGCCGGTATCGAAACAGCTCAATACAGCTACTACAACGCTGAAACCAAAGACAAAGACTTCGCA
GGCATGGTTGCTGACCTAGAGAAAGCTTCTGAAGGCGACATCGTTCTTCTTCACGGCTGCTGTCATAACCCAACAGGCAT
CGACCCAACAACTGAAGAGTGGGAAGTACTTGCTAAGCTAGTTGCTGAGAAGAAACTGCTTCCTCTATTCGATTTTGCCT
ACCAAGGTTTTGCTAAAGGTGTTGAAGAAGATGCAGCTGGCCTGCGCATTTTTGCTCAATACAACAAAGAGATTCTTGTT
GCTAGCTCGTTCTCTAAGAACTTCGGCTTGTACAACGAGCGTGTGGGTGCATTCACTCTGGTTGCAGAATCTGCAGACGT
AGCAACAACAGCGTTCTCTCAAGTTAAGAGCATCATCCGCTCTATCTACTCTAACCCACCAGCGCACGGCAGTGCTGTCG
TTACTCACATCCTTGGTGATGCTGATCTACGTGCTGAATGGGAAGCAGAAGTAGCAGAAATGCGTGACCGTATCCAAGAG
ATGCGCGAGCTATTCGTAACGACACTGAAATCTGAAGGTGTTGATGCAGACTTCACATTCATCGAGCGCCAAAACGGCAT
GTTCTCTTTCTCTGGTTTAAGCAAAGAGCAAGTAACTCGCCTGAAAGACGAATTCGCAATCTACATTGTCGGCTCTGGCC
GTATCAGCGTAGCGGGCATGACGAAGTCAAATATGGGTCCTCTATGTAAAGGCATCGCTGCGGTTCTTTAA

Upstream 100 bases:

>100_bases
TTTTAATAAATTCTAGGTTTTGAGTTGTAACAACCTTGTATGAAAGGTATAAATACCGGAGTTATTATTACCTCCCTCTC
AATTGACATGGATGAAGATT

Downstream 100 bases:

>100_bases
TCGAAAAAGAAACCTGCACTTGCAGACCAATAGATATGCAAAAGCCAGCTATTAAGCTGGCTTTTTTGTGTCTGTCTCCT
TTATATGTCAGTTTTTAAGA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MFEKVLAAPADPILGLTEEFKKDSREEKINLGVGIYKNEDGQTPVLKTVKKAEAALLENEKTKSYLTIEGTAEYGLAVQK
LLFGSDAEIVTSQRAKTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHNGVFAAAGIETAQYSYYNAETKDKDFA
GMVADLEKASEGDIVLLHGCCHNPTGIDPTTEEWEVLAKLVAEKKLLPLFDFAYQGFAKGVEEDAAGLRIFAQYNKEILV
ASSFSKNFGLYNERVGAFTLVAESADVATTAFSQVKSIIRSIYSNPPAHGSAVVTHILGDADLRAEWEAEVAEMRDRIQE
MRELFVTTLKSEGVDADFTFIERQNGMFSFSGLSKEQVTRLKDEFAIYIVGSGRISVAGMTKSNMGPLCKGIAAVL

Sequences:

>Translated_396_residues
MFEKVLAAPADPILGLTEEFKKDSREEKINLGVGIYKNEDGQTPVLKTVKKAEAALLENEKTKSYLTIEGTAEYGLAVQK
LLFGSDAEIVTSQRAKTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHNGVFAAAGIETAQYSYYNAETKDKDFA
GMVADLEKASEGDIVLLHGCCHNPTGIDPTTEEWEVLAKLVAEKKLLPLFDFAYQGFAKGVEEDAAGLRIFAQYNKEILV
ASSFSKNFGLYNERVGAFTLVAESADVATTAFSQVKSIIRSIYSNPPAHGSAVVTHILGDADLRAEWEAEVAEMRDRIQE
MRELFVTTLKSEGVDADFTFIERQNGMFSFSGLSKEQVTRLKDEFAIYIVGSGRISVAGMTKSNMGPLCKGIAAVL
>Mature_396_residues
MFEKVLAAPADPILGLTEEFKKDSREEKINLGVGIYKNEDGQTPVLKTVKKAEAALLENEKTKSYLTIEGTAEYGLAVQK
LLFGSDAEIVTSQRAKTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHNGVFAAAGIETAQYSYYNAETKDKDFA
GMVADLEKASEGDIVLLHGCCHNPTGIDPTTEEWEVLAKLVAEKKLLPLFDFAYQGFAKGVEEDAAGLRIFAQYNKEILV
ASSFSKNFGLYNERVGAFTLVAESADVATTAFSQVKSIIRSIYSNPPAHGSAVVTHILGDADLRAEWEAEVAEMRDRIQE
MRELFVTTLKSEGVDADFTFIERQNGMFSFSGLSKEQVTRLKDEFAIYIVGSGRISVAGMTKSNMGPLCKGIAAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=44.4444444444444, Blast_Score=347, Evalue=1e-95,
Organism=Homo sapiens, GI4504067, Length=386, Percent_Identity=41.9689119170984, Blast_Score=311, Evalue=8e-85,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=25.5874673629243, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=60.1010101010101, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=44.080604534005, Blast_Score=361, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=43.7974683544304, Blast_Score=362, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=40.7594936708861, Blast_Score=327, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=35.1898734177215, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=30.749354005168, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=38.3886255924171, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=32.319391634981, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323055, Length=406, Percent_Identity=36.6995073891626, Blast_Score=291, Evalue=9e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=432, Percent_Identity=34.9537037037037, Blast_Score=254, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=41.4141414141414, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=41.4141414141414, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=41.6452442159383, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=40.6015037593985, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=40.6015037593985, Blast_Score=321, Evalue=5e-88,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43122; Mature: 43122

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKVLAAPADPILGLTEEFKKDSREEKINLGVGIYKNEDGQTPVLKTVKKAEAALLENE
CCCHHHCCCCCCCCCCHHHHHCCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHCCC
KTKSYLTIEGTAEYGLAVQKLLFGSDAEIVTSQRAKTAQAPGGTGALRVAGEFIKRQLGD
CCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
VKIWISNPTWANHNGVFAAAGIETAQYSYYNAETKDKDFAGMVADLEKASEGDIVLLHGC
EEEEECCCCCCCCCCEEEECCCCHHHEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECC
CHNPTGIDPTTEEWEVLAKLVAEKKLLPLFDFAYQGFAKGVEEDAAGLRIFAQYNKEILV
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCEEEEEECCCEEEE
ASSFSKNFGLYNERVGAFTLVAESADVATTAFSQVKSIIRSIYSNPPAHGSAVVTHILGD
EECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
ADLRAEWEAEVAEMRDRIQEMRELFVTTLKSEGVDADFTFIERQNGMFSFSGLSKEQVTR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCHHHHHH
LKDEFAIYIVGSGRISVAGMTKSNMGPLCKGIAAVL
HHCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHC
>Mature Secondary Structure
MFEKVLAAPADPILGLTEEFKKDSREEKINLGVGIYKNEDGQTPVLKTVKKAEAALLENE
CCCHHHCCCCCCCCCCHHHHHCCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHCCC
KTKSYLTIEGTAEYGLAVQKLLFGSDAEIVTSQRAKTAQAPGGTGALRVAGEFIKRQLGD
CCCEEEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
VKIWISNPTWANHNGVFAAAGIETAQYSYYNAETKDKDFAGMVADLEKASEGDIVLLHGC
EEEEECCCCCCCCCCEEEECCCCHHHEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECC
CHNPTGIDPTTEEWEVLAKLVAEKKLLPLFDFAYQGFAKGVEEDAAGLRIFAQYNKEILV
CCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHCCCEEEEEECCCEEEE
ASSFSKNFGLYNERVGAFTLVAESADVATTAFSQVKSIIRSIYSNPPAHGSAVVTHILGD
EECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCC
ADLRAEWEAEVAEMRDRIQEMRELFVTTLKSEGVDADFTFIERQNGMFSFSGLSKEQVTR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCCHHHHHH
LKDEFAIYIVGSGRISVAGMTKSNMGPLCKGIAAVL
HHCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]