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The map label for this gene is ydcR [H]

Identifier: 218709680

GI number: 218709680

Start: 1816428

End: 1817861

Strand: Reverse

Name: ydcR [H]

Synonym: VS_1691

Alternate gene names: 218709680

Gene position: 1817861-1816428 (Counterclockwise)

Preceding gene: 218709681

Following gene: 218709679

Centisome position: 55.1

GC content: 45.61

Gene sequence:

>1434_bases
TTGATGAAAAAATCTCAGATACTCGCCAATACAATCAAGAATCAGATAGAACAAAACATCTGGCTGAGTGGTGAGAAGAT
CCCATCAATTAGAGACGCATGTAAGCGCTATAAACTCAGTATCGAGACGGTACTTCAGGCCTATCAACAGCTTGAAGACC
AAGGCTATGTGCGCTCAAAGCCTAAGTCTGGCTATTTCGTGTTACCGCGTAGAAATGTATTCACCTCAGAACACACGCAA
CAAAAAGCAATCAAGCCGTATCCCGTTAAAATCAGTGACCTGCTTTACGATGTGCTTCAACGAGCCAAAGACCCTAGTAT
TATTCCACTCAGCTCGGCATTTCCAGATCCTGCTTTGTTTCCACATCAAGCGTTGTCGCGCAGTTTAGCCAATGCCAGTC
GTCAAATGCCCGATAACAGCATGCTTACTAATTTGCCACCGGGCAGTGAAACGTTACGCAGGCAAATCGCTCAGCGCTAT
CAAGCTGGTGGGCTAGATGTATTGCCCGACGATATTGTGATCACGTCTGGGGCGATGGAGGCGCTTAATTTATGCCTGCA
ATCCTGTACCGAACCGGGTGACTTAGTCGCTATCGAGTACCCAGCGTTTTACGGTGTGTTACAGACCATAGAAAGGTTAA
ATCTCACTGCCGTAGAGATTCCAACAGACCCGACAACAGGGATTGATTTAGATGTGTTGGAGTCGGTGTTCGCTTCAATG
GATATCAAAGCATGTTGGTTTATGACAGAGTCGCAAAACCCAGTAGGCTATTCGATGAGTGATGGAAACAAGCAGCGATT
GGCCGAGTTGGTGAACCAACATAAGATCCCGATGATCGAAGACGATGTGTATCGAGAACTTCATGTCGGCAACCAAAGCT
CATTACCTGCTAAAGCCTATGACACTAGCGAACAGATCATGCTTTGTGGTTCGTTTTCCAAATCATTGTCACCGGGCTTT
CGAATCGGTTGGGTAGTCGCAAGGAAACAAGCGCTAAAGATACAGAGATTGCAGCACCTTTCGACGCTCTCGAGCAGTAT
TCCTATCCAACTTGGGCTGTCTCACTACCTGACGTTTTATAGTTATGACAATCACCTTAAAAAGCTTCGTAAACTGCTGA
ACGAAAGGAAGAAGGCGCATATAGCACTTCTAGAATCCAGTTTGCCTAAGAGTGCTCTGATTCATAAAAGCCAAGGTGGC
TACTTCATTTGGATAGAACTGCCGCACTCTGTTTGTGTTGAGAAGCTGTATGAACTAGCCCTTGAACAAAACATCTCTGT
CGCACCGGGTATCATATTCAGCAGTGACAAAAAGTTCTCTCATCACATTCGACTCAACTGTTCGTATGCTTGTGACGACA
AAATAGCAGAAGCCATTCGAATGCTAGGCGGCTTGATTCAGGCAATGGAATTGCAAGCCAATAGTTGCAGCTAA

Upstream 100 bases:

>100_bases
GTAATTGGGTTTAGGGTAGGGCTTTGTTATACCTGAATGTCCGAATGCTTCGAATATCCACGGTTTAGTAATCTTTTACA
CATTAGATAGAAAAGACTTT

Downstream 100 bases:

>100_bases
ACTCTGACCAGTCGTTCGTCTAATAAGTAAATCTGTTCTGTTTTTTAACTACTTATCTGTTCTAGTTTGGTTTGTTCAAA
CTGTGCTGAAATACGCTCCA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMKKSQILANTIKNQIEQNIWLSGEKIPSIRDACKRYKLSIETVLQAYQQLEDQGYVRSKPKSGYFVLPRRNVFTSEHTQ
QKAIKPYPVKISDLLYDVLQRAKDPSIIPLSSAFPDPALFPHQALSRSLANASRQMPDNSMLTNLPPGSETLRRQIAQRY
QAGGLDVLPDDIVITSGAMEALNLCLQSCTEPGDLVAIEYPAFYGVLQTIERLNLTAVEIPTDPTTGIDLDVLESVFASM
DIKACWFMTESQNPVGYSMSDGNKQRLAELVNQHKIPMIEDDVYRELHVGNQSSLPAKAYDTSEQIMLCGSFSKSLSPGF
RIGWVVARKQALKIQRLQHLSTLSSSIPIQLGLSHYLTFYSYDNHLKKLRKLLNERKKAHIALLESSLPKSALIHKSQGG
YFIWIELPHSVCVEKLYELALEQNISVAPGIIFSSDKKFSHHIRLNCSYACDDKIAEAIRMLGGLIQAMELQANSCS

Sequences:

>Translated_477_residues
MMKKSQILANTIKNQIEQNIWLSGEKIPSIRDACKRYKLSIETVLQAYQQLEDQGYVRSKPKSGYFVLPRRNVFTSEHTQ
QKAIKPYPVKISDLLYDVLQRAKDPSIIPLSSAFPDPALFPHQALSRSLANASRQMPDNSMLTNLPPGSETLRRQIAQRY
QAGGLDVLPDDIVITSGAMEALNLCLQSCTEPGDLVAIEYPAFYGVLQTIERLNLTAVEIPTDPTTGIDLDVLESVFASM
DIKACWFMTESQNPVGYSMSDGNKQRLAELVNQHKIPMIEDDVYRELHVGNQSSLPAKAYDTSEQIMLCGSFSKSLSPGF
RIGWVVARKQALKIQRLQHLSTLSSSIPIQLGLSHYLTFYSYDNHLKKLRKLLNERKKAHIALLESSLPKSALIHKSQGG
YFIWIELPHSVCVEKLYELALEQNISVAPGIIFSSDKKFSHHIRLNCSYACDDKIAEAIRMLGGLIQAMELQANSCS
>Mature_477_residues
MMKKSQILANTIKNQIEQNIWLSGEKIPSIRDACKRYKLSIETVLQAYQQLEDQGYVRSKPKSGYFVLPRRNVFTSEHTQ
QKAIKPYPVKISDLLYDVLQRAKDPSIIPLSSAFPDPALFPHQALSRSLANASRQMPDNSMLTNLPPGSETLRRQIAQRY
QAGGLDVLPDDIVITSGAMEALNLCLQSCTEPGDLVAIEYPAFYGVLQTIERLNLTAVEIPTDPTTGIDLDVLESVFASM
DIKACWFMTESQNPVGYSMSDGNKQRLAELVNQHKIPMIEDDVYRELHVGNQSSLPAKAYDTSEQIMLCGSFSKSLSPGF
RIGWVVARKQALKIQRLQHLSTLSSSIPIQLGLSHYLTFYSYDNHLKKLRKLLNERKKAHIALLESSLPKSALIHKSQGG
YFIWIELPHSVCVEKLYELALEQNISVAPGIIFSSDKKFSHHIRLNCSYACDDKIAEAIRMLGGLIQAMELQANSCS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=426, Percent_Identity=24.4131455399061, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI33469970, Length=426, Percent_Identity=24.4131455399061, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4507369, Length=237, Percent_Identity=23.2067510548523, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1787710, Length=466, Percent_Identity=46.5665236051502, Blast_Score=440, Evalue=1e-124,
Organism=Escherichia coli, GI1790797, Length=473, Percent_Identity=31.9238900634249, Blast_Score=271, Evalue=7e-74,
Organism=Escherichia coli, GI48994949, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=8e-12,
Organism=Drosophila melanogaster, GI18859735, Length=223, Percent_Identity=25.1121076233184, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53460; Mature: 53460

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKSQILANTIKNQIEQNIWLSGEKIPSIRDACKRYKLSIETVLQAYQQLEDQGYVRSK
CCCHHHHHHHHHHHHHHHCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKSGYFVLPRRNVFTSEHTQQKAIKPYPVKISDLLYDVLQRAKDPSIIPLSSAFPDPALF
CCCCEEEEECCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCC
PHQALSRSLANASRQMPDNSMLTNLPPGSETLRRQIAQRYQAGGLDVLPDDIVITSGAME
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHH
ALNLCLQSCTEPGDLVAIEYPAFYGVLQTIERLNLTAVEIPTDPTTGIDLDVLESVFASM
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHC
DIKACWFMTESQNPVGYSMSDGNKQRLAELVNQHKIPMIEDDVYRELHVGNQSSLPAKAY
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
DTSEQIMLCGSFSKSLSPGFRIGWVVARKQALKIQRLQHLSTLSSSIPIQLGLSHYLTFY
CCCCCEEEEECCHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
SYDNHLKKLRKLLNERKKAHIALLESSLPKSALIHKSQGGYFIWIELPHSVCVEKLYELA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEECCHHHHHHHHHHHH
LEQNISVAPGIIFSSDKKFSHHIRLNCSYACDDKIAEAIRMLGGLIQAMELQANSCS
HHCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMKKSQILANTIKNQIEQNIWLSGEKIPSIRDACKRYKLSIETVLQAYQQLEDQGYVRSK
CCCHHHHHHHHHHHHHHHCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKSGYFVLPRRNVFTSEHTQQKAIKPYPVKISDLLYDVLQRAKDPSIIPLSSAFPDPALF
CCCCEEEEECCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCC
PHQALSRSLANASRQMPDNSMLTNLPPGSETLRRQIAQRYQAGGLDVLPDDIVITSGAME
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHH
ALNLCLQSCTEPGDLVAIEYPAFYGVLQTIERLNLTAVEIPTDPTTGIDLDVLESVFASM
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHC
DIKACWFMTESQNPVGYSMSDGNKQRLAELVNQHKIPMIEDDVYRELHVGNQSSLPAKAY
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
DTSEQIMLCGSFSKSLSPGFRIGWVVARKQALKIQRLQHLSTLSSSIPIQLGLSHYLTFY
CCCCCEEEEECCHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
SYDNHLKKLRKLLNERKKAHIALLESSLPKSALIHKSQGGYFIWIELPHSVCVEKLYELA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCEEEEEECCHHHHHHHHHHHH
LEQNISVAPGIIFSSDKKFSHHIRLNCSYACDDKIAEAIRMLGGLIQAMELQANSCS
HHCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]