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The map label for this gene is hlyB [H]

Identifier: 218709626

GI number: 218709626

Start: 1755737

End: 1757518

Strand: Reverse

Name: hlyB [H]

Synonym: VS_1636

Alternate gene names: 218709626

Gene position: 1757518-1755737 (Counterclockwise)

Preceding gene: 218709627

Following gene: 218709625

Centisome position: 53.27

GC content: 44.33

Gene sequence:

>1782_bases
ATGTATATGAATATAAAGAAAAAGCTCTATTCGTTGGGGGTGTTCTCCATCTTCGGCATGATTTCATTGTTGTTTACCAC
ATCTCAATTTGCGGACACCACCGCTAAAATGAGCGAAGCCAAACAAATTACCAAAGAACTTGAAGTGCGACTACTCAACC
TTCGTCGTAACGAGAAAGATTTCTTACTTCGCAGTGATCTGAAATACCTCGACAAGTTCGACGTAAATTACAAAAAATTC
TTAGCGTCTGAATCTGAGCTTAATGCTGTGCTGAATGGTCTGGGTTTGGCCAACAGTACGCATTTGCGTGAAGATATCGA
AACGTACCACACAAGCTTTGTTAACCTTGTTAAAGCCAGCCAAGTGTATGGACTAACACGAGACAGAGGCTTGTTAGGGG
AATTTCATGCTGTACTCGATAACATCAGTGCCACCGCGAGTGCTGAACAAAAAATTGAGCTGTATCTCTTCAATGATCTG
ATCGAGAAGGGTGAGTTCGACCCAAGTGTTCTGTCTATTACTTCTAATGCGGGTGGCTCAGCTGCTTTGATAGAAGCAGC
TCGTCAAGTCGTAGATCAGAAACGAGTGATAGGGTTAAAACATAACGAAGGGTTATTAGGGCAAGCGCGCACAGGTTCGC
ACGTTATCGAGACTCAATTCAAAGAATTCTCGGCCGTGTTAGATCAACAGGCACAGCAAGAGATGGATAAACTATCGCTG
ATCAACAACACCCTTTGCGTCACACTGTTAGTGGCGATCATTCTATTCAGCTGGTTAATCGTACGTTCAATCATCGGTAA
GATTGAATCTCTACTTACTGTGATCCGTAACATTGTCGATTCGAACGACGTGTCTATTCGAGCGACGGAGAATGGCAAAG
ACGAACTCGGTAAGCTAGGCGAATACTTCAATCAACTGCTAGATCAGCTTGAAGGGTTGATTGCAACGTCTCAATCTAAG
TCACATCAGTTGACACAAAGTACGTCGAGCATGCATGACGAGCTGGAATCGGTCATCAAACAGTTCGAAGTTCAAGCAAA
CCACACCTCAACAATGACAACTTCAGTGCAAGAGATGGTACTGACTATTGGGGAAATATCAGAAAGTACATCGGTTGCCG
CTGAAGGCGTTCATCAAGCGAAAGTGAATGCCGACAAAGGTCGTGAAGTGGTGGTTGATACCATCAATAACATTACCCAG
TTGTCTGAACGCCTTTCAAGTAGCCAAGATTCGATTAGTTCTTTGAATCACCATGTCGATCAAATTGGTAGTGCCGTTAA
CATTATCCAAGGTATTGCGGAACAGACTAATTTATTGGCACTGAACGCAGCCATTGAAGCCGCTCGTGCTGGTGAGCAAG
GTCGTGGCTTTGCAGTTGTTGCGGATGAAGTCCGAGCGTTAGCAAGCAGAACGCACCAATCAACCACTGAAATCACCAGT
GTAGTCACTGCAATCCAGAGCCAAATGAATGCTTCTATGACAGAGATTGGCGAGTGTAACCAACAAGGCCAGCTGACACT
TAAAGATTCAGAAGAATTGGATGCAAGCTTGCAACTGATCTTGAGTGATATGGAAAGCATTCAAGGCAACTCAGAACGTA
TTGCTTCAGCGATTGAAGAACAGGGTGCCGTAATGACACAAGTGAGTGACTCAATTACTGAGTTGAATACCATCTCGAAT
GATAACAACGCTTCGGCGCAGCATTGCTTGGTCGAAGTCGATAAAGTAGCTGAGCAAGCGAACGATATGGATCAAGCGGT
AGCGCAGTTTAAGACGTCATAA

Upstream 100 bases:

>100_bases
ACTGATAAAAATCATAACAATAACTCGATCGCACTAGCCGTATATCCATGCTTTGATGCGATCAATTAGATACTTATAGT
TAATTTAGTAAAGACGAGCC

Downstream 100 bases:

>100_bases
GATTTCTAGAGCAAGCTATCAACCAAAGCCGTGAATTATTTGAAACCCAAGGCGCGAATTATTCGCGCCTTTTTTGGGTC
TGAAGGATAGGCAAGTTCCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MYMNIKKKLYSLGVFSIFGMISLLFTTSQFADTTAKMSEAKQITKELEVRLLNLRRNEKDFLLRSDLKYLDKFDVNYKKF
LASESELNAVLNGLGLANSTHLREDIETYHTSFVNLVKASQVYGLTRDRGLLGEFHAVLDNISATASAEQKIELYLFNDL
IEKGEFDPSVLSITSNAGGSAALIEAARQVVDQKRVIGLKHNEGLLGQARTGSHVIETQFKEFSAVLDQQAQQEMDKLSL
INNTLCVTLLVAIILFSWLIVRSIIGKIESLLTVIRNIVDSNDVSIRATENGKDELGKLGEYFNQLLDQLEGLIATSQSK
SHQLTQSTSSMHDELESVIKQFEVQANHTSTMTTSVQEMVLTIGEISESTSVAAEGVHQAKVNADKGREVVVDTINNITQ
LSERLSSSQDSISSLNHHVDQIGSAVNIIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASRTHQSTTEITS
VVTAIQSQMNASMTEIGECNQQGQLTLKDSEELDASLQLILSDMESIQGNSERIASAIEEQGAVMTQVSDSITELNTISN
DNNASAQHCLVEVDKVAEQANDMDQAVAQFKTS

Sequences:

>Translated_593_residues
MYMNIKKKLYSLGVFSIFGMISLLFTTSQFADTTAKMSEAKQITKELEVRLLNLRRNEKDFLLRSDLKYLDKFDVNYKKF
LASESELNAVLNGLGLANSTHLREDIETYHTSFVNLVKASQVYGLTRDRGLLGEFHAVLDNISATASAEQKIELYLFNDL
IEKGEFDPSVLSITSNAGGSAALIEAARQVVDQKRVIGLKHNEGLLGQARTGSHVIETQFKEFSAVLDQQAQQEMDKLSL
INNTLCVTLLVAIILFSWLIVRSIIGKIESLLTVIRNIVDSNDVSIRATENGKDELGKLGEYFNQLLDQLEGLIATSQSK
SHQLTQSTSSMHDELESVIKQFEVQANHTSTMTTSVQEMVLTIGEISESTSVAAEGVHQAKVNADKGREVVVDTINNITQ
LSERLSSSQDSISSLNHHVDQIGSAVNIIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASRTHQSTTEITS
VVTAIQSQMNASMTEIGECNQQGQLTLKDSEELDASLQLILSDMESIQGNSERIASAIEEQGAVMTQVSDSITELNTISN
DNNASAQHCLVEVDKVAEQANDMDQAVAQFKTS
>Mature_593_residues
MYMNIKKKLYSLGVFSIFGMISLLFTTSQFADTTAKMSEAKQITKELEVRLLNLRRNEKDFLLRSDLKYLDKFDVNYKKF
LASESELNAVLNGLGLANSTHLREDIETYHTSFVNLVKASQVYGLTRDRGLLGEFHAVLDNISATASAEQKIELYLFNDL
IEKGEFDPSVLSITSNAGGSAALIEAARQVVDQKRVIGLKHNEGLLGQARTGSHVIETQFKEFSAVLDQQAQQEMDKLSL
INNTLCVTLLVAIILFSWLIVRSIIGKIESLLTVIRNIVDSNDVSIRATENGKDELGKLGEYFNQLLDQLEGLIATSQSK
SHQLTQSTSSMHDELESVIKQFEVQANHTSTMTTSVQEMVLTIGEISESTSVAAEGVHQAKVNADKGREVVVDTINNITQ
LSERLSSSQDSISSLNHHVDQIGSAVNIIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASRTHQSTTEITS
VVTAIQSQMNASMTEIGECNQQGQLTLKDSEELDASLQLILSDMESIQGNSERIASAIEEQGAVMTQVSDSITELNTISN
DNNASAQHCLVEVDKVAEQANDMDQAVAQFKTS

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=345, Percent_Identity=26.3768115942029, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI2367378, Length=347, Percent_Identity=27.6657060518732, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788194, Length=248, Percent_Identity=33.8709677419355, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789453, Length=334, Percent_Identity=27.5449101796407, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=27.1641791044776, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64899; Mature: 64899

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMNIKKKLYSLGVFSIFGMISLLFTTSQFADTTAKMSEAKQITKELEVRLLNLRRNEKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FLLRSDLKYLDKFDVNYKKFLASESELNAVLNGLGLANSTHLREDIETYHTSFVNLVKAS
HHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
QVYGLTRDRGLLGEFHAVLDNISATASAEQKIELYLFNDLIEKGEFDPSVLSITSNAGGS
HHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
AALIEAARQVVDQKRVIGLKHNEGLLGQARTGSHVIETQFKEFSAVLDQQAQQEMDKLSL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
INNTLCVTLLVAIILFSWLIVRSIIGKIESLLTVIRNIVDSNDVSIRATENGKDELGKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
EYFNQLLDQLEGLIATSQSKSHQLTQSTSSMHDELESVIKQFEVQANHTSTMTTSVQEMV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LTIGEISESTSVAAEGVHQAKVNADKGREVVVDTINNITQLSERLSSSQDSISSLNHHVD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QIGSAVNIIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASRTHQSTTEITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
VVTAIQSQMNASMTEIGECNQQGQLTLKDSEELDASLQLILSDMESIQGNSERIASAIEE
HHHHHHHHHCCHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QGAVMTQVSDSITELNTISNDNNASAQHCLVEVDKVAEQANDMDQAVAQFKTS
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYMNIKKKLYSLGVFSIFGMISLLFTTSQFADTTAKMSEAKQITKELEVRLLNLRRNEKD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FLLRSDLKYLDKFDVNYKKFLASESELNAVLNGLGLANSTHLREDIETYHTSFVNLVKAS
HHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
QVYGLTRDRGLLGEFHAVLDNISATASAEQKIELYLFNDLIEKGEFDPSVLSITSNAGGS
HHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCH
AALIEAARQVVDQKRVIGLKHNEGLLGQARTGSHVIETQFKEFSAVLDQQAQQEMDKLSL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
INNTLCVTLLVAIILFSWLIVRSIIGKIESLLTVIRNIVDSNDVSIRATENGKDELGKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHH
EYFNQLLDQLEGLIATSQSKSHQLTQSTSSMHDELESVIKQFEVQANHTSTMTTSVQEMV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LTIGEISESTSVAAEGVHQAKVNADKGREVVVDTINNITQLSERLSSSQDSISSLNHHVD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QIGSAVNIIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALASRTHQSTTEITS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
VVTAIQSQMNASMTEIGECNQQGQLTLKDSEELDASLQLILSDMESIQGNSERIASAIEE
HHHHHHHHHCCHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
QGAVMTQVSDSITELNTISNDNNASAQHCLVEVDKVAEQANDMDQAVAQFKTS
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]