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The map label for this gene is hlyB [H]

Identifier: 218709501

GI number: 218709501

Start: 1644972

End: 1647017

Strand: Reverse

Name: hlyB [H]

Synonym: VS_1510

Alternate gene names: 218709501

Gene position: 1647017-1644972 (Counterclockwise)

Preceding gene: 218709503

Following gene: 218709499

Centisome position: 49.92

GC content: 44.13

Gene sequence:

>2046_bases
ATGCCCGACACAAATTTATCAATAAAACCTTCACGTTATACATTCTCGCTCATTCAAACCGTCACCGCTGTATTTATTTC
CATTCTTTTGCTCGTCATCTTTTTATCTTTGGTCAGTCTCCGAGGCGTCGATCGGGTCGGGGGCCATTTTGAAGCACTTT
CGGAACAAGCATTACCTCTTGCATTAAACAACGCCGAATTAACACAAAGCGTGTTGGAGCAGGTAAAACTTCTTACTTAT
AGCACCCAATCAACCGACCTAAATACGCTTAGCACAACAGGCAACTCGATCGACGTGTTAGTTGCCGAAAGTAACCAAAC
GCTAGAAGAACTCCTCTTCATATCCCAATCTTTTCCTGACGCGATTTCCGTTGAACAAAAACAAAACTTAATCGAGAACA
TGGCGACCTTACAATTGATGACTAGCCAAGTGTTGTCGTCACAAATCGAAATTCAGAATAAGCAAAACCTCATCGATGGC
CAAGTCACTGAGTTTCGCTATGGTGTGAGTTCCATCGGACCTGAAATGAACCGTATCAGTTCTTTCCTTGTTCAGAACAA
CCCAGAGGCTTCCGATGCGGCTAACCGATTCACAGCGAGTGCTTCTGCAATGGCGAACACCTTCCTAATGTTGATGATGC
AATCAGACTTAGAAAAAGCGCAAGACGAATACAGAGAGCTTCGAAATCGAATTGCAGGCATTAACCTCGCGTATGATGAC
TTTTCTGAATGGCATCCAGACATCGTAGAGTTCGCAAGCTTAACAGCGCCTTATGAGATGGTTAAATCTGGCTTTGCAGA
TAACGGTGTATTAAGACAAATCCTGCAAAAGCTAGAACTTGTTGAGCAACAAGAAGCCGACTTAGCAAAAGTCATCCATC
TGGCCAACACCGTGATAGGGACCTTAAATCAACTATCGAACACCGCTTCCATTTTAATTGATGAAAGCGAGTTTGTGGTC
AATCAGACAATTGCGACGATAGACAAAGTACTATTTATTAGTGGATTAGTGATAGCAGCTATCATTTCTATTTCATGGTT
GGTGTTACGTCGTTGGGTGAACAAAGGACTCAGAAACATTACTCAACAAATGAGCTTACTCGCGGAACACGATTTTTCAA
AACAGAGTCAATTAGTTGGCCCATTGGAATTGCAAGTTATTGCGTCAAAACTTAATTCTGTTGTCGACTCAACCGCTGAT
TCGGTGCGTTTGGTAACACGAAACTGTGAAACGCTTTATCAAACAGCGGAAGTCAGTCACGATGCCGCAGAGCAAACTAA
CTCAAGCTTACACGAGCAAAATGAATCGCTTCAGAACATGATTACTACCATTACAGAGCTTGAAGCATCTATTGGTGAAA
TTGCACGTATTTCTAACGCCTCAAATGATGACGCCCAGCTTGCTGAAAATGAGTCAGTAACAGGGAGCCAAGTTGTTGGA
CTTAACCAGCAGCGACTGCATGCACTAGAACACTCTTTAAGCATGAATGAAGAATCGATGGCCGACTTAGACGGACGTGT
TAAACAGATTCGCGAAATGGTCGACATGATCAGTGGCATTGCTGACAACACTAACTTACTCGCATTGAATGCAGCAATAG
AAGCAGCTCGAGCAGGAGATCAAGGCCGAGGCTTTGCAGTGGTTGCCGATGAAGTCAGAAAACTTGCCAGCGATACTTCT
CAGCAAACCACTAATATACGAAATATGATGAATGAATTGGTGGCAGCCGCTGACCGATCACGCGCTTCTGTAACAGAATC
GAGAAGCGAAATGGCGAATGCACTGGAAACCAGTGGCGATGTAAAGCAGGCCTTCGAGAAAATCGAATTCGCGGTTAGCC
AGATCAAAGGGCGTGTTGAGCAAATCATGGTGGCGACTGAGCAACAAGCTCGCGCGACTGTCGATGTAACGCATTCTATC
ACTCGCGTGTCTGAGCAGGGAGAGAATACTAAGTTACAGCTTGAATCCATGATCGAGAGTTCAGAGCAAGTCGGAGAGAT
AGCAGGACACCAACAAGCTATGCTTCATAAATACGTGTTGAAATAA

Upstream 100 bases:

>100_bases
AACTCTTCTGACAAAAAACTGAAATATAAACGTCATCAAGGACTTCTAGTATACGAACTAACTTAAGGATATCTTTTTTC
GTAGTCAAACTGGATTTCAC

Downstream 100 bases:

>100_bases
ACGAGCGTGTTGAGTTAAGCCTGACAGCATAATAGTTGAAGCACTAAGTACGCTTAAATTCCTATTGATACAGAAACGCC
CTTAAGTTTTCACAAGAATC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 680

Protein sequence:

>681_residues
MPDTNLSIKPSRYTFSLIQTVTAVFISILLLVIFLSLVSLRGVDRVGGHFEALSEQALPLALNNAELTQSVLEQVKLLTY
STQSTDLNTLSTTGNSIDVLVAESNQTLEELLFISQSFPDAISVEQKQNLIENMATLQLMTSQVLSSQIEIQNKQNLIDG
QVTEFRYGVSSIGPEMNRISSFLVQNNPEASDAANRFTASASAMANTFLMLMMQSDLEKAQDEYRELRNRIAGINLAYDD
FSEWHPDIVEFASLTAPYEMVKSGFADNGVLRQILQKLELVEQQEADLAKVIHLANTVIGTLNQLSNTASILIDESEFVV
NQTIATIDKVLFISGLVIAAIISISWLVLRRWVNKGLRNITQQMSLLAEHDFSKQSQLVGPLELQVIASKLNSVVDSTAD
SVRLVTRNCETLYQTAEVSHDAAEQTNSSLHEQNESLQNMITTITELEASIGEIARISNASNDDAQLAENESVTGSQVVG
LNQQRLHALEHSLSMNEESMADLDGRVKQIREMVDMISGIADNTNLLALNAAIEAARAGDQGRGFAVVADEVRKLASDTS
QQTTNIRNMMNELVAAADRSRASVTESRSEMANALETSGDVKQAFEKIEFAVSQIKGRVEQIMVATEQQARATVDVTHSI
TRVSEQGENTKLQLESMIESSEQVGEIAGHQQAMLHKYVLK

Sequences:

>Translated_681_residues
MPDTNLSIKPSRYTFSLIQTVTAVFISILLLVIFLSLVSLRGVDRVGGHFEALSEQALPLALNNAELTQSVLEQVKLLTY
STQSTDLNTLSTTGNSIDVLVAESNQTLEELLFISQSFPDAISVEQKQNLIENMATLQLMTSQVLSSQIEIQNKQNLIDG
QVTEFRYGVSSIGPEMNRISSFLVQNNPEASDAANRFTASASAMANTFLMLMMQSDLEKAQDEYRELRNRIAGINLAYDD
FSEWHPDIVEFASLTAPYEMVKSGFADNGVLRQILQKLELVEQQEADLAKVIHLANTVIGTLNQLSNTASILIDESEFVV
NQTIATIDKVLFISGLVIAAIISISWLVLRRWVNKGLRNITQQMSLLAEHDFSKQSQLVGPLELQVIASKLNSVVDSTAD
SVRLVTRNCETLYQTAEVSHDAAEQTNSSLHEQNESLQNMITTITELEASIGEIARISNASNDDAQLAENESVTGSQVVG
LNQQRLHALEHSLSMNEESMADLDGRVKQIREMVDMISGIADNTNLLALNAAIEAARAGDQGRGFAVVADEVRKLASDTS
QQTTNIRNMMNELVAAADRSRASVTESRSEMANALETSGDVKQAFEKIEFAVSQIKGRVEQIMVATEQQARATVDVTHSI
TRVSEQGENTKLQLESMIESSEQVGEIAGHQQAMLHKYVLK
>Mature_680_residues
PDTNLSIKPSRYTFSLIQTVTAVFISILLLVIFLSLVSLRGVDRVGGHFEALSEQALPLALNNAELTQSVLEQVKLLTYS
TQSTDLNTLSTTGNSIDVLVAESNQTLEELLFISQSFPDAISVEQKQNLIENMATLQLMTSQVLSSQIEIQNKQNLIDGQ
VTEFRYGVSSIGPEMNRISSFLVQNNPEASDAANRFTASASAMANTFLMLMMQSDLEKAQDEYRELRNRIAGINLAYDDF
SEWHPDIVEFASLTAPYEMVKSGFADNGVLRQILQKLELVEQQEADLAKVIHLANTVIGTLNQLSNTASILIDESEFVVN
QTIATIDKVLFISGLVIAAIISISWLVLRRWVNKGLRNITQQMSLLAEHDFSKQSQLVGPLELQVIASKLNSVVDSTADS
VRLVTRNCETLYQTAEVSHDAAEQTNSSLHEQNESLQNMITTITELEASIGEIARISNASNDDAQLAENESVTGSQVVGL
NQQRLHALEHSLSMNEESMADLDGRVKQIREMVDMISGIADNTNLLALNAAIEAARAGDQGRGFAVVADEVRKLASDTSQ
QTTNIRNMMNELVAAADRSRASVTESRSEMANALETSGDVKQAFEKIEFAVSQIKGRVEQIMVATEQQARATVDVTHSIT
RVSEQGENTKLQLESMIESSEQVGEIAGHQQAMLHKYVLK

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=435, Percent_Identity=25.5172413793103, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788194, Length=332, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788195, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI2367378, Length=298, Percent_Identity=26.1744966442953, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789453, Length=245, Percent_Identity=27.7551020408163, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 74859; Mature: 74728

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTNLSIKPSRYTFSLIQTVTAVFISILLLVIFLSLVSLRGVDRVGGHFEALSEQALPL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCCCE
ALNNAELTQSVLEQVKLLTYSTQSTDLNTLSTTGNSIDVLVAESNQTLEELLFISQSFPD
EECCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
AISVEQKQNLIENMATLQLMTSQVLSSQIEIQNKQNLIDGQVTEFRYGVSSIGPEMNRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHCHHHHHHH
SFLVQNNPEASDAANRFTASASAMANTFLMLMMQSDLEKAQDEYRELRNRIAGINLAYDD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHC
FSEWHPDIVEFASLTAPYEMVKSGFADNGVLRQILQKLELVEQQEADLAKVIHLANTVIG
HHHCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLNQLSNTASILIDESEFVVNQTIATIDKVLFISGLVIAAIISISWLVLRRWVNKGLRNI
HHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQQMSLLAEHDFSKQSQLVGPLELQVIASKLNSVVDSTADSVRLVTRNCETLYQTAEVSH
HHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DAAEQTNSSLHEQNESLQNMITTITELEASIGEIARISNASNDDAQLAENESVTGSQVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEC
LNQQRLHALEHSLSMNEESMADLDGRVKQIREMVDMISGIADNTNLLALNAAIEAARAGD
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
QGRGFAVVADEVRKLASDTSQQTTNIRNMMNELVAAADRSRASVTESRSEMANALETSGD
CCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCH
VKQAFEKIEFAVSQIKGRVEQIMVATEQQARATVDVTHSITRVSEQGENTKLQLESMIES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SEQVGEIAGHQQAMLHKYVLK
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDTNLSIKPSRYTFSLIQTVTAVFISILLLVIFLSLVSLRGVDRVGGHFEALSEQALPL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHCCCCCE
ALNNAELTQSVLEQVKLLTYSTQSTDLNTLSTTGNSIDVLVAESNQTLEELLFISQSFPD
EECCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHCCCC
AISVEQKQNLIENMATLQLMTSQVLSSQIEIQNKQNLIDGQVTEFRYGVSSIGPEMNRIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHCHHHHHHH
SFLVQNNPEASDAANRFTASASAMANTFLMLMMQSDLEKAQDEYRELRNRIAGINLAYDD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHC
FSEWHPDIVEFASLTAPYEMVKSGFADNGVLRQILQKLELVEQQEADLAKVIHLANTVIG
HHHCCHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLNQLSNTASILIDESEFVVNQTIATIDKVLFISGLVIAAIISISWLVLRRWVNKGLRNI
HHHHHCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQQMSLLAEHDFSKQSQLVGPLELQVIASKLNSVVDSTADSVRLVTRNCETLYQTAEVSH
HHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
DAAEQTNSSLHEQNESLQNMITTITELEASIGEIARISNASNDDAQLAENESVTGSQVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCEEC
LNQQRLHALEHSLSMNEESMADLDGRVKQIREMVDMISGIADNTNLLALNAAIEAARAGD
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCC
QGRGFAVVADEVRKLASDTSQQTTNIRNMMNELVAAADRSRASVTESRSEMANALETSGD
CCCCEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCH
VKQAFEKIEFAVSQIKGRVEQIMVATEQQARATVDVTHSITRVSEQGENTKLQLESMIES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SEQVGEIAGHQQAMLHKYVLK
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]