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The map label for this gene is fixN [H]

Identifier: 218709450

GI number: 218709450

Start: 1592554

End: 1593987

Strand: Direct

Name: fixN [H]

Synonym: VS_1459

Alternate gene names: 218709450

Gene position: 1592554-1593987 (Clockwise)

Preceding gene: 218709445

Following gene: 218709451

Centisome position: 48.27

GC content: 45.4

Gene sequence:

>1434_bases
ATGCAAATGAGCCAAGAAAAGCAGCTTGAACAAAACTACAACTATACGGTCGTCCGTCAATTTACCCTCGTTACAATTTT
GTGGGGTATTGTCGGTATGGGCGTTGGTGTTTTGATTGCCGCTCAATTAGTTTGGCCACAGCTAAACTTTGATACGCCGT
GGCTGACGTACAGTCGTTTACGTCCCCTGCATACTAATGCGGTTATTTTTGCGTTCGGTACAAGTGCGCTGTTTGCAACA
TCATATTATGTTGTGCAACGTACCTGTCAGACGCGTCTCTTTGGTGGCCCTCTCGTAGCCTTTACCTTTTGGGGTTGGCA
AGCGATTATCCTGTCCGCTGCAATTACTTTACCGTTAGGTTTAACCTCTGGTAAAGAATACGCAGAACTTGAATGGCCAA
TCGATATTGCTATTACTCTTGTGTGGGTAGCTTATGCGGTCGTGTTCTTCGGAACCATGATTAAGCGTAAGACATCGCAC
ATTTATGTAGCTAACTGGTTCTTCGGAGCCTTCATCATCACGGTTGCCGTGTTGCACATCGTTAACAGCCTGGCTGTTCC
TGTATCTGCGTTTAAATCGTACTCGATTTATTCCGGAGCGATCGATGCAATGGTGCAATGGTGGTACGGACACAATGCGG
TAGGCTTCCTATTGACAGCTGGTTTCCTAGGTATGATGTATTACTTCGTTCCTAAACAAGCTGGTCGCCCTGTTTACTCT
TACCGTTTGTCGATTGTTCACTTCTGGGCTCTTGTGTCTCTGTATATTTGGGCTGGTCCTCACCACCTACACTACACAGC
ACTTCCAGACTGGACTCAGTCTCTAGGTATGGTTATGTCTTTGGTTCTGTTTGCTCCATCTTGGGGTGGCATGATCAACG
GTATTATGACTCTATCTGGTGCGTGGCATAAGCTACGCTACGACCCTATCCTACGTTTCCTAATCGTTTCTCTATCATTC
TACGGCATGTCGACTTTCGAAGGCCCTATGATGGCAATCAAAACGGTTAACGCACTATCTCACTACACGGACTGGACTAT
CGGTCACGTTCACTCTGGTGCGCTAGGTTGGGTTGCGATGGTTTCTATCGGTTCGGTTTACCACTTAGTTCCTAAACTAT
TTGGTCAAGAGCGTATGTACTCTGTATCTCTAATCAATGTTCACTTCTGGTTAGCAACGATTGGTACGGTTTTCTACATT
GTTGCAATGTGGATTTCTGGTGTGATGCAAGGTCTGATGTGGCGTGCAGTTAACTCTGACGGTACATTAACTTACAGCTT
CGTTGAATCTGTAGAAGCATCTTACCCGTTCTACTTTGTACGTTTCTTAGGGGGCTTCATCTTCCTATCTGGTATGTTCT
TAATGGCATACAACACGTACAAAACTGTTTCTGCACCTAAAGATAGCCTTAAAGCTATCCCTCAACCGGCTTAA

Upstream 100 bases:

>100_bases
AATAAAGCTCTGAATAGGCTGAATTTCCTTTTCTAATTTGGGTGGCATTACGACGTGAGTCGTGTTGGAAGTAAAGTGTA
GTAAATAAGAAATTGGAAGC

Downstream 100 bases:

>100_bases
GGAGATTTAGAATGAGCTCAAATTCAAATAATCGCCATGAGTTGGTAGAGAAGAACGTTGGCCTACTGGCGATCTTGATC
GTTATTGCTATCAGTTTTGG

Product: cbb3-type cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome CBB3 subunit 1; Cytochrome c oxidase polypeptide I homolog; Heme B/copper cytochrome c oxidase subunit [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFAT
SYYVVQRTCQTRLFGGPLVAFTFWGWQAIILSAAITLPLGLTSGKEYAELEWPIDIAITLVWVAYAVVFFGTMIKRKTSH
IYVANWFFGAFIITVAVLHIVNSLAVPVSAFKSYSIYSGAIDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAGRPVYS
YRLSIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSF
YGMSTFEGPMMAIKTVNALSHYTDWTIGHVHSGALGWVAMVSIGSVYHLVPKLFGQERMYSVSLINVHFWLATIGTVFYI
VAMWISGVMQGLMWRAVNSDGTLTYSFVESVEASYPFYFVRFLGGFIFLSGMFLMAYNTYKTVSAPKDSLKAIPQPA

Sequences:

>Translated_477_residues
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFAT
SYYVVQRTCQTRLFGGPLVAFTFWGWQAIILSAAITLPLGLTSGKEYAELEWPIDIAITLVWVAYAVVFFGTMIKRKTSH
IYVANWFFGAFIITVAVLHIVNSLAVPVSAFKSYSIYSGAIDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAGRPVYS
YRLSIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSF
YGMSTFEGPMMAIKTVNALSHYTDWTIGHVHSGALGWVAMVSIGSVYHLVPKLFGQERMYSVSLINVHFWLATIGTVFYI
VAMWISGVMQGLMWRAVNSDGTLTYSFVESVEASYPFYFVRFLGGFIFLSGMFLMAYNTYKTVSAPKDSLKAIPQPA
>Mature_477_residues
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMGVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFAT
SYYVVQRTCQTRLFGGPLVAFTFWGWQAIILSAAITLPLGLTSGKEYAELEWPIDIAITLVWVAYAVVFFGTMIKRKTSH
IYVANWFFGAFIITVAVLHIVNSLAVPVSAFKSYSIYSGAIDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAGRPVYS
YRLSIVHFWALVSLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSF
YGMSTFEGPMMAIKTVNALSHYTDWTIGHVHSGALGWVAMVSIGSVYHLVPKLFGQERMYSVSLINVHFWLATIGTVFYI
VAMWISGVMQGLMWRAVNSDGTLTYSFVESVEASYPFYFVRFLGGFIFLSGMFLMAYNTYKTVSAPKDSLKAIPQPA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 53680; Mature: 53680

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure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CCEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8386371; 12597275 [H]