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The map label for this gene is vsm [H]

Identifier: 218709260

GI number: 218709260

Start: 1365498

End: 1367321

Strand: Reverse

Name: vsm [H]

Synonym: VS_1267

Alternate gene names: 218709260

Gene position: 1367321-1365498 (Counterclockwise)

Preceding gene: 218709275

Following gene: 218709259

Centisome position: 41.44

GC content: 47.2

Gene sequence:

>1824_bases
ATGAACCAACAACGTCAACTAAGCTGGAAAATAGCAGCTATTCTAGGTACATCTTTTGGCTTTAATGCACACGCTGCAGA
AATGGTCAGAGTCGATAATGATGCATTACTCCAACAGAGCCTCGTCGCTCAGTCGAAGAGTGTTGCTCCACTTGAATTAG
GTTTTTCTGAAGTTAAACGGGTGGTATTGCCCAATGGAAAAACGAAAGTTCGCTACCAACAAACTCACCTAGGTTTACCC
GTCTTTGATACTTCGGTCGTGGCCACCCTTTCCAAGAACCAACCCACTCAAGTGTTCGGTTCCATGGCACAGGGGATCAG
TGGTGATCTATCCAGCATCGCGCCAAAACTGAATCAGGAACAAGCGATAGAAGCTGCGATCTCCTCTCACCGCACGTTTA
CCGTCGGCAAAAAGTCGATTGAAAATAAAAACGCGAAACTGATGGTGAGATTGGATGAGAACCAAGTCGCCCAAGTGGTG
TATCTGGTCGATTTCTTTATCGCATCCTCTATGCCAGAACGCCCTTTCTACTTTATTGATGCCACGACTGGCGATGTGAT
CCAAAAATGGAATGGACTAAACCACGCTAAAGCATTAGGTACTGGCCCAGGTGGCAACCTCAAAACCACTCTATATGAAT
ATGGCAGTGACTTCCCTAGCTTTCCCATCGACAAAACAGGCACGACTTGTACGTTAGAAAATGAATCAGTTAAGACCGTC
GATTTGAGGAACGGAACGTCTGGCAGCGCAGCCTACAGCTACAACTGTGCCGACGGAACCAACTACACCGATCATAAATA
CATCAACGGGGCTTACTCGCCTCTCAACGATGCGCACTATTTTGGTAATGTCGTATTCGATATGTACAAAGAGTGGATGA
ACACGTCGCCTTTAACTTTCCAGCTGACGATGCGTGTTCATTACGGTACCGATTATGAAAATGCTTTCTGGAATGGTACA
TCCATGACTTTTGGAGATGGCAAAAATACCTTTTACCCATTGGTCGATATCAACGTGAGTGCTCACGAAGTCAGCCACGG
CTTCACTGAGCAAAACTCCGGCCTTGTGTACCAAAACATGTCGGGCGGTATCAATGAAGCCTTCTCCGATATTGCAGGCG
AAGCGGCTGAATACTACCTGCGTGGTAATGTCGATTGGGTGGTCGGAAGCGATATATTCAAATCAGAAGGCGGCTTGCGT
TACTTCGATCAACCTTCAAAAGATGGCCGCTCGATTGATCACGCCTCTCAATACTACGATGGTTTGAACGTTCACTTATC
TAGCGGTGTTTATAACCGCGCCTTTTACCTTTTAGCGAACAAATCGGGTTGGAATGTACGTAAGGGCTTTGAAATATTCA
CAGTCGCAAACCAACTGTATTGGACGGCAAACAGTACCTTTGATGCCGGTGCGTGTGGCGTAGCGAAAGCCGCTGCAGAC
ATGGGCTATGTGGTTGCCGATGTTGAAGATGCTTTTAATACCGTAGGCGTGAATGCGAGTTGTGGTTCAACGCCACCAAC
TGGCAATGTGCTGACGAAAGGCACACCAATTACGAACCTAAGCGGGAACCAATCTTCAGAGAGCTTCTACACGTTCACTG
TTGATTCTGCATCCAGCGTGACGGTTTCAATGTCTGGTGGTTCAGGTGATGCCGATCTTTATGTGAAATCGGGAAGCAAG
CCAACAACATCAAGTTACGACTGTCGCCCTTACCGTGCTGGAAACAATGAGCAGTGTAGTGTGAGCGCTCAACCGGGTGT
GACCTATCATGTGTTACTGCGCGGATACTCGAACTACTCTGGCCTAACGTTACGTTTAGATTGA

Upstream 100 bases:

>100_bases
TCCAATCTTGATTCGCAACACATGGCACAGATGTGTTGCATATAGACTTCCTATAAAGCCGTTGGGAAGAAGGAGTTTAT
ATTAAAATCAGGAACGAAAA

Downstream 100 bases:

>100_bases
GTTGGAGCGAGCCTCTCAAACAAGTTGTGAATCGAGAACTAGCGGTTAACCGCGAAATAAAAACCTACTCACTTTGAGTA
GGTTTTTTTATGACACACCG

Product: extracellular zinc metalloprotease

Products: NA

Alternate protein names: Aeromonolysin; Vibriolysin [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MNQQRQLSWKIAAILGTSFGFNAHAAEMVRVDNDALLQQSLVAQSKSVAPLELGFSEVKRVVLPNGKTKVRYQQTHLGLP
VFDTSVVATLSKNQPTQVFGSMAQGISGDLSSIAPKLNQEQAIEAAISSHRTFTVGKKSIENKNAKLMVRLDENQVAQVV
YLVDFFIASSMPERPFYFIDATTGDVIQKWNGLNHAKALGTGPGGNLKTTLYEYGSDFPSFPIDKTGTTCTLENESVKTV
DLRNGTSGSAAYSYNCADGTNYTDHKYINGAYSPLNDAHYFGNVVFDMYKEWMNTSPLTFQLTMRVHYGTDYENAFWNGT
SMTFGDGKNTFYPLVDINVSAHEVSHGFTEQNSGLVYQNMSGGINEAFSDIAGEAAEYYLRGNVDWVVGSDIFKSEGGLR
YFDQPSKDGRSIDHASQYYDGLNVHLSSGVYNRAFYLLANKSGWNVRKGFEIFTVANQLYWTANSTFDAGACGVAKAAAD
MGYVVADVEDAFNTVGVNASCGSTPPTGNVLTKGTPITNLSGNQSSESFYTFTVDSASSVTVSMSGGSGDADLYVKSGSK
PTTSSYDCRPYRAGNNEQCSVSAQPGVTYHVLLRGYSNYSGLTLRLD

Sequences:

>Translated_607_residues
MNQQRQLSWKIAAILGTSFGFNAHAAEMVRVDNDALLQQSLVAQSKSVAPLELGFSEVKRVVLPNGKTKVRYQQTHLGLP
VFDTSVVATLSKNQPTQVFGSMAQGISGDLSSIAPKLNQEQAIEAAISSHRTFTVGKKSIENKNAKLMVRLDENQVAQVV
YLVDFFIASSMPERPFYFIDATTGDVIQKWNGLNHAKALGTGPGGNLKTTLYEYGSDFPSFPIDKTGTTCTLENESVKTV
DLRNGTSGSAAYSYNCADGTNYTDHKYINGAYSPLNDAHYFGNVVFDMYKEWMNTSPLTFQLTMRVHYGTDYENAFWNGT
SMTFGDGKNTFYPLVDINVSAHEVSHGFTEQNSGLVYQNMSGGINEAFSDIAGEAAEYYLRGNVDWVVGSDIFKSEGGLR
YFDQPSKDGRSIDHASQYYDGLNVHLSSGVYNRAFYLLANKSGWNVRKGFEIFTVANQLYWTANSTFDAGACGVAKAAAD
MGYVVADVEDAFNTVGVNASCGSTPPTGNVLTKGTPITNLSGNQSSESFYTFTVDSASSVTVSMSGGSGDADLYVKSGSK
PTTSSYDCRPYRAGNNEQCSVSAQPGVTYHVLLRGYSNYSGLTLRLD
>Mature_607_residues
MNQQRQLSWKIAAILGTSFGFNAHAAEMVRVDNDALLQQSLVAQSKSVAPLELGFSEVKRVVLPNGKTKVRYQQTHLGLP
VFDTSVVATLSKNQPTQVFGSMAQGISGDLSSIAPKLNQEQAIEAAISSHRTFTVGKKSIENKNAKLMVRLDENQVAQVV
YLVDFFIASSMPERPFYFIDATTGDVIQKWNGLNHAKALGTGPGGNLKTTLYEYGSDFPSFPIDKTGTTCTLENESVKTV
DLRNGTSGSAAYSYNCADGTNYTDHKYINGAYSPLNDAHYFGNVVFDMYKEWMNTSPLTFQLTMRVHYGTDYENAFWNGT
SMTFGDGKNTFYPLVDINVSAHEVSHGFTEQNSGLVYQNMSGGINEAFSDIAGEAAEYYLRGNVDWVVGSDIFKSEGGLR
YFDQPSKDGRSIDHASQYYDGLNVHLSSGVYNRAFYLLANKSGWNVRKGFEIFTVANQLYWTANSTFDAGACGVAKAAAD
MGYVVADVEDAFNTVGVNASCGSTPPTGNVLTKGTPITNLSGNQSSESFYTFTVDSASSVTVSMSGGSGDADLYVKSGSK
PTTSSYDCRPYRAGNNEQCSVSAQPGVTYHVLLRGYSNYSGLTLRLD

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR007280
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C; PF04151 PPC [H]

EC number: =3.4.24.25 [H]

Molecular weight: Translated: 65956; Mature: 65956

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQRQLSWKIAAILGTSFGFNAHAAEMVRVDNDALLQQSLVAQSKSVAPLELGFSEVKR
CCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHE
VVLPNGKTKVRYQQTHLGLPVFDTSVVATLSKNQPTQVFGSMAQGISGDLSSIAPKLNQE
EECCCCCCEEEEEHHHCCCCEECCCEEEEECCCCCHHHHHHHHCCCCCCHHHHCCCCCHH
QAIEAAISSHRTFTVGKKSIENKNAKLMVRLDENQVAQVVYLVDFFIASSMPERPFYFID
HHHHHHHHCCCEEEECHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEE
ATTGDVIQKWNGLNHAKALGTGPGGNLKTTLYEYGSDFPSFPIDKTGTTCTLENESVKTV
CCCHHHHHHCCCCCHHHCCCCCCCCCCEEHHEECCCCCCCCCCCCCCCEEEECCCCEEEE
DLRNGTSGSAAYSYNCADGTNYTDHKYINGAYSPLNDAHYFGNVVFDMYKEWMNTSPLTF
EECCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
QLTMRVHYGTDYENAFWNGTSMTFGDGKNTFYPLVDINVSAHEVSHGFTEQNSGLVYQNM
EEEEEEEECCCCCCCEECCCEEEECCCCCEEEEEEEECCCHHHHHCCCCCCCCCEEEECC
SGGINEAFSDIAGEAAEYYLRGNVDWVVGSDIFKSEGGLRYFDQPSKDGRSIDHASQYYD
CCCHHHHHHHHHCCCEEEEEECCEEEEECCHHHHCCCCEEECCCCCCCCCCCHHHHHHCC
GLNVHLSSGVYNRAFYLLANKSGWNVRKGFEIFTVANQLYWTANSTFDAGACGVAKAAAD
CCEEEECCCCCCEEEEEEECCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHHHHHH
MGYVVADVEDAFNTVGVNASCGSTPPTGNVLTKGTPITNLSGNQSSESFYTFTVDSASSV
CCEEEEEHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCEE
TVSMSGGSGDADLYVKSGSKPTTSSYDCRPYRAGNNEQCSVSAQPGVTYHVLLRGYSNYS
EEEECCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCEEEEECCCCCEEEEEEECCCCCC
GLTLRLD
CEEEEEC
>Mature Secondary Structure
MNQQRQLSWKIAAILGTSFGFNAHAAEMVRVDNDALLQQSLVAQSKSVAPLELGFSEVKR
CCCCCCCEEEEEEEEECCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHHE
VVLPNGKTKVRYQQTHLGLPVFDTSVVATLSKNQPTQVFGSMAQGISGDLSSIAPKLNQE
EECCCCCCEEEEEHHHCCCCEECCCEEEEECCCCCHHHHHHHHCCCCCCHHHHCCCCCHH
QAIEAAISSHRTFTVGKKSIENKNAKLMVRLDENQVAQVVYLVDFFIASSMPERPFYFID
HHHHHHHHCCCEEEECHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCEEEEE
ATTGDVIQKWNGLNHAKALGTGPGGNLKTTLYEYGSDFPSFPIDKTGTTCTLENESVKTV
CCCHHHHHHCCCCCHHHCCCCCCCCCCEEHHEECCCCCCCCCCCCCCCEEEECCCCEEEE
DLRNGTSGSAAYSYNCADGTNYTDHKYINGAYSPLNDAHYFGNVVFDMYKEWMNTSPLTF
EECCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
QLTMRVHYGTDYENAFWNGTSMTFGDGKNTFYPLVDINVSAHEVSHGFTEQNSGLVYQNM
EEEEEEEECCCCCCCEECCCEEEECCCCCEEEEEEEECCCHHHHHCCCCCCCCCEEEECC
SGGINEAFSDIAGEAAEYYLRGNVDWVVGSDIFKSEGGLRYFDQPSKDGRSIDHASQYYD
CCCHHHHHHHHHCCCEEEEEECCEEEEECCHHHHCCCCEEECCCCCCCCCCCHHHHHHCC
GLNVHLSSGVYNRAFYLLANKSGWNVRKGFEIFTVANQLYWTANSTFDAGACGVAKAAAD
CCEEEECCCCCCEEEEEEECCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCHHHHHHHH
MGYVVADVEDAFNTVGVNASCGSTPPTGNVLTKGTPITNLSGNQSSESFYTFTVDSASSV
CCEEEEEHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCEE
TVSMSGGSGDADLYVKSGSKPTTSSYDCRPYRAGNNEQCSVSAQPGVTYHVLLRGYSNYS
EEEECCCCCCEEEEEECCCCCCCCCCCCCCEECCCCCEEEEECCCCCEEEEEEECCCCCC
GLTLRLD
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1551587 [H]