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The map label for this gene is hutI [H]

Identifier: 218709212

GI number: 218709212

Start: 1295530

End: 1296786

Strand: Reverse

Name: hutI [H]

Synonym: VS_1219

Alternate gene names: 218709212

Gene position: 1296786-1295530 (Counterclockwise)

Preceding gene: 218709213

Following gene: 218709211

Centisome position: 39.3

GC content: 48.85

Gene sequence:

>1257_bases
GTGATTATGAATTTGATCCTCAAAAACGCACGAGTGGTCTCGATGAGCTCGGGAGCCGATGGTTATCAGCCCTCTTCCCC
TAAAGATATCGTTATCGAAGACGGTAAGATCGTGTCCATCTATTGTTCAAACCAAGGCGTACGTGCTTCTGAGTTAGAAC
AAGTAAGTATTGATGGTTCTTTGGATTACATCACCTATGATTGCAAAAACAAGTTAGTCACCCCTGGGCTGATTGATTGC
CACACTCACCTCGTATTTGCGGGTAATCGTGCCAATGAATTTGAGCAGCGTTTGAATGGTGTGTCTTACACCGACATCGC
CAAGCAAGGCGGCGGCATTCTGGCGACAGTAACCGCGACCCGCGCAGCGCAAGAATCCGAACTGGTTGAAATGGCTTTAC
CTAGACTCGATGGCCTGCTACGAAGCGGCGTAACCAGCATTGAAGTAAAATCTGGCTATGGTTTAACACTTGAAGATGAG
CTCAAGATGTTACGCGCAGCTAAAGCGTTAGAGAACCATCGCCGAATTAAGATCACCACCACTCTCCTTGCAGCCCATGC
TGTGCCACCTGAATATAAAGAACAACCGGACAGCTATATCGATCTGGTTTGCCAAGAGATCATTCCTAAAGCTGCAGAGC
AAGGCCTAGCCGATGCGGTTGACGTGTTCTGTGAATCTATCGGCTTCAACCTTGAACAAACCGAACGTGTATTTGCAGCA
GCCAAAGAACACGGACTAGCGATTAAAGGCCACACAGAACAGCTTTCAAATATGGGCGGCAGCGCGCTCGCCGCTAAATA
CGGTGCACTCTCTGTCGATCATGTTGAGTACCTTGATGAAACCGGAGTCAAGGCACTAGCGGAATCAGGCACAGTTGCGA
CCTTGCTACCCGGCGCTTTCTATTTCCTTAAAGAGACTCAACAACCACCCGTTGCCCTGCTTCGTGAACACAACATTCCA
ATGGCGATCGCGACCGACTTAAACCCCGGCACGTCTCCCTTTGCTGATTTAACGCTGATGATGAACATGAGCTGCACCTT
ATTTGGCACGACGCCTGAAGAAGCGCTGCGCGGTGTGACTAGTCATGCTGCGGCTGCCATTGGCGACTCACAAACTAAAG
GCAAAATTGAAATTGGTTATGCCGCTGATTTAGCTATCTGGAATATCGAGCACCCTGCCGATCTAAGCTATCAAGTCGGT
GTTCCTCATCTGCATAAACGCATTGTTAATGGCGAGGTGTGTCATGACTCAATCTAA

Upstream 100 bases:

>100_bases
CATCCTGATCGCCGATCACATTTTTGCAACATCAACTTGATTCGGGTCAGAGTTTAGCCTATTTATTTGTATATACATTT
AATGTTTAGTAAAGATCTAG

Downstream 100 bases:

>100_bases
ATCCAACGGTATCCAAGAGAACGCAACAACCATGCATAACTTTGTGTGGACAGGGCGTAATGATCTTGAAGATGGCGCAC
TCGGTACTCGCGTTCATCAC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIMNLILKNARVVSMSSGADGYQPSSPKDIVIEDGKIVSIYCSNQGVRASELEQVSIDGSLDYITYDCKNKLVTPGLIDC
HTHLVFAGNRANEFEQRLNGVSYTDIAKQGGGILATVTATRAAQESELVEMALPRLDGLLRSGVTSIEVKSGYGLTLEDE
LKMLRAAKALENHRRIKITTTLLAAHAVPPEYKEQPDSYIDLVCQEIIPKAAEQGLADAVDVFCESIGFNLEQTERVFAA
AKEHGLAIKGHTEQLSNMGGSALAAKYGALSVDHVEYLDETGVKALAESGTVATLLPGAFYFLKETQQPPVALLREHNIP
MAIATDLNPGTSPFADLTLMMNMSCTLFGTTPEEALRGVTSHAAAAIGDSQTKGKIEIGYAADLAIWNIEHPADLSYQVG
VPHLHKRIVNGEVCHDSI

Sequences:

>Translated_418_residues
MIMNLILKNARVVSMSSGADGYQPSSPKDIVIEDGKIVSIYCSNQGVRASELEQVSIDGSLDYITYDCKNKLVTPGLIDC
HTHLVFAGNRANEFEQRLNGVSYTDIAKQGGGILATVTATRAAQESELVEMALPRLDGLLRSGVTSIEVKSGYGLTLEDE
LKMLRAAKALENHRRIKITTTLLAAHAVPPEYKEQPDSYIDLVCQEIIPKAAEQGLADAVDVFCESIGFNLEQTERVFAA
AKEHGLAIKGHTEQLSNMGGSALAAKYGALSVDHVEYLDETGVKALAESGTVATLLPGAFYFLKETQQPPVALLREHNIP
MAIATDLNPGTSPFADLTLMMNMSCTLFGTTPEEALRGVTSHAAAAIGDSQTKGKIEIGYAADLAIWNIEHPADLSYQVG
VPHLHKRIVNGEVCHDSI
>Mature_418_residues
MIMNLILKNARVVSMSSGADGYQPSSPKDIVIEDGKIVSIYCSNQGVRASELEQVSIDGSLDYITYDCKNKLVTPGLIDC
HTHLVFAGNRANEFEQRLNGVSYTDIAKQGGGILATVTATRAAQESELVEMALPRLDGLLRSGVTSIEVKSGYGLTLEDE
LKMLRAAKALENHRRIKITTTLLAAHAVPPEYKEQPDSYIDLVCQEIIPKAAEQGLADAVDVFCESIGFNLEQTERVFAA
AKEHGLAIKGHTEQLSNMGGSALAAKYGALSVDHVEYLDETGVKALAESGTVATLLPGAFYFLKETQQPPVALLREHNIP
MAIATDLNPGTSPFADLTLMMNMSCTLFGTTPEEALRGVTSHAAAAIGDSQTKGKIEIGYAADLAIWNIEHPADLSYQVG
VPHLHKRIVNGEVCHDSI

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=342, Percent_Identity=37.4269005847953, Blast_Score=206, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17555004, Length=368, Percent_Identity=32.6086956521739, Blast_Score=206, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 44979; Mature: 44979

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMNLILKNARVVSMSSGADGYQPSSPKDIVIEDGKIVSIYCSNQGVRASELEQVSIDGS
CEEHEEECCCEEEEECCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCHHHCCEEEECCC
LDYITYDCKNKLVTPGLIDCHTHLVFAGNRANEFEQRLNGVSYTDIAKQGGGILATVTAT
EEEEEEECCCCCCCCCEEECEEEEEEECCCHHHHHHHHCCCCHHHHHHCCCCEEEEEEHH
RAAQESELVEMALPRLDGLLRSGVTSIEVKSGYGLTLEDELKMLRAAKALENHRRIKITT
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
TLLAAHAVPPEYKEQPDSYIDLVCQEIIPKAAEQGLADAVDVFCESIGFNLEQTERVFAA
EEHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
AKEHGLAIKGHTEQLSNMGGSALAAKYGALSVDHVEYLDETGVKALAESGTVATLLPGAF
HHHCCEEEECCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
YFLKETQQPPVALLREHNIPMAIATDLNPGTSPFADLTLMMNMSCTLFGTTPEEALRGVT
EEHHCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHEEEEEECEEEEEECCHHHHHHHHH
SHAAAAIGDSQTKGKIEIGYAADLAIWNIEHPADLSYQVGVPHLHKRIVNGEVCHDSI
HHHHHHCCCCCCCCEEEEEEEEEEEEEECCCCCCCEEECCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIMNLILKNARVVSMSSGADGYQPSSPKDIVIEDGKIVSIYCSNQGVRASELEQVSIDGS
CEEHEEECCCEEEEECCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCHHHCCEEEECCC
LDYITYDCKNKLVTPGLIDCHTHLVFAGNRANEFEQRLNGVSYTDIAKQGGGILATVTAT
EEEEEEECCCCCCCCCEEECEEEEEEECCCHHHHHHHHCCCCHHHHHHCCCCEEEEEEHH
RAAQESELVEMALPRLDGLLRSGVTSIEVKSGYGLTLEDELKMLRAAKALENHRRIKITT
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
TLLAAHAVPPEYKEQPDSYIDLVCQEIIPKAAEQGLADAVDVFCESIGFNLEQTERVFAA
EEHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHH
AKEHGLAIKGHTEQLSNMGGSALAAKYGALSVDHVEYLDETGVKALAESGTVATLLPGAF
HHHCCEEEECCHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
YFLKETQQPPVALLREHNIPMAIATDLNPGTSPFADLTLMMNMSCTLFGTTPEEALRGVT
EEHHCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHEEEEEECEEEEEECCHHHHHHHHH
SHAAAAIGDSQTKGKIEIGYAADLAIWNIEHPADLSYQVGVPHLHKRIVNGEVCHDSI
HHHHHHCCCCCCCCEEEEEEEEEEEEEECCCCCCCEEECCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA