Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 218709056

GI number: 218709056

Start: 1116580

End: 1118697

Strand: Direct

Name: hlyB [H]

Synonym: VS_1062

Alternate gene names: 218709056

Gene position: 1116580-1118697 (Clockwise)

Preceding gene: 218709052

Following gene: 218709062

Centisome position: 33.84

GC content: 44.95

Gene sequence:

>2118_bases
ATGCGCTCTCTATCAGTACAGTGGAAAATAACCCTCTTAGCAGGTTGTTGTTTAATCATTACGTCACTGTCTCTCATTGG
TTTCTCGATCTACAACGCGACGAGCAATCAACAGGTCATAAAATCTCAAAGCTCAGAATCAGTGATTAACAAAACTCAAC
AGTTGTTGGCATCCGTTTCTCAGCTTAATGCTCAGGAAACTCAACGTTATGTCGATGAAGCTATTTATCGAGCAGAAATG
TTGGCTTCTAGTGCTCAGTTTCTAAAGAACAACGCAGACGAAAACTTTACCCCAAGTGAAGAGCTTCGTACTGCGTTAGA
TGAAATGGTTCGTCGTTCTGTTTTGAACTTTGATTCTATTCAAGGAGCTTACCTAGTCTTCAAGCCCGATTTACTTGATG
CTGAAGATGCGAATTATGTCGATGCGGATTATGTCGGCTCGAATGAAAGAGGGCGTTTTGCTCCTTATTGGAAGGTCGCA
GATAATGGCGAGAACGTTCTTCCAAACGTGTTATCAGAATCAACATTGAGTGATAACAGCAATAGCGAACGCTTTTTCTG
TCCTTTGTCATCTGGACAAACGTGTATTAGTACGCCAAGAGTTGTGAGTAGCGGTGGTCAAGAACTGCTTACGTCTTCGA
TTTCGGTGCCTATCATCGTTGATGATGTAGCGATTGGTTTCTTGGGCATCGACTTAAGGCTCGATGGTTTGACCAATGTT
GTCACTCAATCGGATCAAAGCTTGTTTGAAGGTGCAGGCGCGGTTTACGTCGTGAGTTTAGATGGTTCCGTTATCGCTTC
TGATGATCAAAGTATTGCGGTTGGTTCGAGTTTTCAAAGCAACAATACAAGTAGCGATCTAATGACGGACTTTATCTTTG
GTGGTGAAGTCACGACTCAATGGAGTGAGAATGGTGAGTGGTTACTCGCATTTGCACCTGTTGTTGCCGCCAACCAAACT
TGGGGTGTGCTGTTTGAGATTCCAAGAGAGAGTGTGGTTGCTGACGCAAATCAATTGGATGCCATTATTAGTACTAAGCT
AAGTGAAGGTATTAAGACTGAAGTGATTGCGGGTATTAGCTTTATTCTTTTCGGTCTAGCGATCATCGCTTTTGCTTCAC
TGTCCATTGTTAAGCCTATTCGACAGGTAGTTGAGAGACTGAACGATATTGCTTCTGGTGAAGGTGATTTAACGCAACGC
TTGGAAGTGAAATCTCAAGACGAAATTGGTCAGTTGTCACAAGGGTTTAACCTGTTCTTAGACAAGCTTCAACACACGAT
TAAAGAGGTGATTCAGACCACTGAGCAAGTGGCGAGCACGACAAGCCAGGCGAAGGCCTCTGCATCAAGTACTCGTGAAA
GTAGTGAGTCTCAGTTTAAAGAAGTGGATCTTGTGGCGACCGCGGCAGAAGAGATGACTCAGACTTCGGGCTTAGTGGTA
CAAAATGCTGAAATAGCCGTTGATGCCGCTTGTGAAGCGAATCGTTCTGCTCAGCAAGGCCAACAGGTTATCGAACTTTC
TGCCGGTGAGATGAGAAAGCTGGTGGCTCGTATGTCGAGCGCCGTGCCTATTGTTGAAGAGTTGGCTAAAAATAACGGTA
ACATCACTGAGATCTTAAGTGTGATTGAAGGGATCTCTGAGCAAACCAACTTACTGGCATTGAATGCCGCGATTGAAGCG
GCTCGTGCAGGTGAGCAAGGTCGAGGTTTTGCCGTCGTTGCTGATGAGGTAAGAAATCTCGCAAGCCGCACACAGTCATC
GGTTGGTGAAATCAGAGCGGTGATCGACAAAGTCCACGCGGGTACTCAAGATGTCGTTGAAGCGATACAAGAAGGTAATA
TTCTCGCTAACGACACGGCATTACATGTTCAAAAAGCGGTCGAAGATCTGGGTTCGATCTTTACTTCTATAGAAGCGATC
AGTGATATGAACAACCAGATCGTGAGAGCGGCAGAAGAGCAACAATCGGTTTCCGGTGAAGTGAACCAAAGTGTCGTTAA
TATCCGTGATTTGAGTGCGAAGATCTTGGATCAAGCCGCAGCTTCTGAACAAGTGGGTAGCGAAATTGACCAACTGTCCC
AACAGCAGCAGAAATTGGTTAATCAGTTCAAGGTTTAG

Upstream 100 bases:

>100_bases
CTAAGCTATTCGTCTAACTCATTCACATTGTGCATAGCAGTTTGTTACTAATGTGATGGTTACGGTTATGGAAGTCTTTT
GGCTTAAATAAGGATATTAA

Downstream 100 bases:

>100_bases
TCTAGTTGTTCACTGTATAGCTTTTAAGCTTAGTTAACAATTGAATAGAAAAAGGGACAAATGAAGATTTCATTTGCCCC
TTTTATTTTTCTTGGGCTCT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MRSLSVQWKITLLAGCCLIITSLSLIGFSIYNATSNQQVIKSQSSESVINKTQQLLASVSQLNAQETQRYVDEAIYRAEM
LASSAQFLKNNADENFTPSEELRTALDEMVRRSVLNFDSIQGAYLVFKPDLLDAEDANYVDADYVGSNERGRFAPYWKVA
DNGENVLPNVLSESTLSDNSNSERFFCPLSSGQTCISTPRVVSSGGQELLTSSISVPIIVDDVAIGFLGIDLRLDGLTNV
VTQSDQSLFEGAGAVYVVSLDGSVIASDDQSIAVGSSFQSNNTSSDLMTDFIFGGEVTTQWSENGEWLLAFAPVVAANQT
WGVLFEIPRESVVADANQLDAIISTKLSEGIKTEVIAGISFILFGLAIIAFASLSIVKPIRQVVERLNDIASGEGDLTQR
LEVKSQDEIGQLSQGFNLFLDKLQHTIKEVIQTTEQVASTTSQAKASASSTRESSESQFKEVDLVATAAEEMTQTSGLVV
QNAEIAVDAACEANRSAQQGQQVIELSAGEMRKLVARMSSAVPIVEELAKNNGNITEILSVIEGISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRNLASRTQSSVGEIRAVIDKVHAGTQDVVEAIQEGNILANDTALHVQKAVEDLGSIFTSIEAI
SDMNNQIVRAAEEQQSVSGEVNQSVVNIRDLSAKILDQAAASEQVGSEIDQLSQQQQKLVNQFKV

Sequences:

>Translated_705_residues
MRSLSVQWKITLLAGCCLIITSLSLIGFSIYNATSNQQVIKSQSSESVINKTQQLLASVSQLNAQETQRYVDEAIYRAEM
LASSAQFLKNNADENFTPSEELRTALDEMVRRSVLNFDSIQGAYLVFKPDLLDAEDANYVDADYVGSNERGRFAPYWKVA
DNGENVLPNVLSESTLSDNSNSERFFCPLSSGQTCISTPRVVSSGGQELLTSSISVPIIVDDVAIGFLGIDLRLDGLTNV
VTQSDQSLFEGAGAVYVVSLDGSVIASDDQSIAVGSSFQSNNTSSDLMTDFIFGGEVTTQWSENGEWLLAFAPVVAANQT
WGVLFEIPRESVVADANQLDAIISTKLSEGIKTEVIAGISFILFGLAIIAFASLSIVKPIRQVVERLNDIASGEGDLTQR
LEVKSQDEIGQLSQGFNLFLDKLQHTIKEVIQTTEQVASTTSQAKASASSTRESSESQFKEVDLVATAAEEMTQTSGLVV
QNAEIAVDAACEANRSAQQGQQVIELSAGEMRKLVARMSSAVPIVEELAKNNGNITEILSVIEGISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRNLASRTQSSVGEIRAVIDKVHAGTQDVVEAIQEGNILANDTALHVQKAVEDLGSIFTSIEAI
SDMNNQIVRAAEEQQSVSGEVNQSVVNIRDLSAKILDQAAASEQVGSEIDQLSQQQQKLVNQFKV
>Mature_705_residues
MRSLSVQWKITLLAGCCLIITSLSLIGFSIYNATSNQQVIKSQSSESVINKTQQLLASVSQLNAQETQRYVDEAIYRAEM
LASSAQFLKNNADENFTPSEELRTALDEMVRRSVLNFDSIQGAYLVFKPDLLDAEDANYVDADYVGSNERGRFAPYWKVA
DNGENVLPNVLSESTLSDNSNSERFFCPLSSGQTCISTPRVVSSGGQELLTSSISVPIIVDDVAIGFLGIDLRLDGLTNV
VTQSDQSLFEGAGAVYVVSLDGSVIASDDQSIAVGSSFQSNNTSSDLMTDFIFGGEVTTQWSENGEWLLAFAPVVAANQT
WGVLFEIPRESVVADANQLDAIISTKLSEGIKTEVIAGISFILFGLAIIAFASLSIVKPIRQVVERLNDIASGEGDLTQR
LEVKSQDEIGQLSQGFNLFLDKLQHTIKEVIQTTEQVASTTSQAKASASSTRESSESQFKEVDLVATAAEEMTQTSGLVV
QNAEIAVDAACEANRSAQQGQQVIELSAGEMRKLVARMSSAVPIVEELAKNNGNITEILSVIEGISEQTNLLALNAAIEA
ARAGEQGRGFAVVADEVRNLASRTQSSVGEIRAVIDKVHAGTQDVVEAIQEGNILANDTALHVQKAVEDLGSIFTSIEAI
SDMNNQIVRAAEEQQSVSGEVNQSVVNIRDLSAKILDQAAASEQVGSEIDQLSQQQQKLVNQFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=31.4754098360656, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788195, Length=325, Percent_Identity=30.7692307692308, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI1788194, Length=322, Percent_Identity=31.6770186335404, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1787690, Length=346, Percent_Identity=30.635838150289, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=257, Percent_Identity=34.2412451361868, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 75820; Mature: 75820

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLSVQWKITLLAGCCLIITSLSLIGFSIYNATSNQQVIKSQSSESVINKTQQLLASVS
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHH
QLNAQETQRYVDEAIYRAEMLASSAQFLKNNADENFTPSEELRTALDEMVRRSVLNFDSI
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QGAYLVFKPDLLDAEDANYVDADYVGSNERGRFAPYWKVADNGENVLPNVLSESTLSDNS
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCC
NSERFFCPLSSGQTCISTPRVVSSGGQELLTSSISVPIIVDDVAIGFLGIDLRLDGLTNV
CCCEEEEECCCCCCCCCCCHHHHCCCHHHHHCCCCCCEEECCHHEEEEEEEEEECCHHHH
VTQSDQSLFEGAGAVYVVSLDGSVIASDDQSIAVGSSFQSNNTSSDLMTDFIFGGEVTTQ
HHCCHHHHHCCCCEEEEEEECCCEEECCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEE
WSENGEWLLAFAPVVAANQTWGVLFEIPRESVVADANQLDAIISTKLSEGIKTEVIAGIS
ECCCCCEEEEECCHHHCCCCCCEEEECCCHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHH
FILFGLAIIAFASLSIVKPIRQVVERLNDIASGEGDLTQRLEVKSQDEIGQLSQGFNLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
DKLQHTIKEVIQTTEQVASTTSQAKASASSTRESSESQFKEVDLVATAAEEMTQTSGLVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
QNAEIAVDAACEANRSAQQGQQVIELSAGEMRKLVARMSSAVPIVEELAKNNGNITEILS
ECCCEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHH
VIEGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSVGEIRAVIDKVHA
HHHCCCHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTQDVVEAIQEGNILANDTALHVQKAVEDLGSIFTSIEAISDMNNQIVRAAEEQQSVSGE
CHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VNQSVVNIRDLSAKILDQAAASEQVGSEIDQLSQQQQKLVNQFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSLSVQWKITLLAGCCLIITSLSLIGFSIYNATSNQQVIKSQSSESVINKTQQLLASVS
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHH
QLNAQETQRYVDEAIYRAEMLASSAQFLKNNADENFTPSEELRTALDEMVRRSVLNFDSI
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
QGAYLVFKPDLLDAEDANYVDADYVGSNERGRFAPYWKVADNGENVLPNVLSESTLSDNS
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCC
NSERFFCPLSSGQTCISTPRVVSSGGQELLTSSISVPIIVDDVAIGFLGIDLRLDGLTNV
CCCEEEEECCCCCCCCCCCHHHHCCCHHHHHCCCCCCEEECCHHEEEEEEEEEECCHHHH
VTQSDQSLFEGAGAVYVVSLDGSVIASDDQSIAVGSSFQSNNTSSDLMTDFIFGGEVTTQ
HHCCHHHHHCCCCEEEEEEECCCEEECCCCCEEECCCCCCCCCHHHHHHHHHCCCCEEEE
WSENGEWLLAFAPVVAANQTWGVLFEIPRESVVADANQLDAIISTKLSEGIKTEVIAGIS
ECCCCCEEEEECCHHHCCCCCCEEEECCCHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHH
FILFGLAIIAFASLSIVKPIRQVVERLNDIASGEGDLTQRLEVKSQDEIGQLSQGFNLFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
DKLQHTIKEVIQTTEQVASTTSQAKASASSTRESSESQFKEVDLVATAAEEMTQTSGLVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
QNAEIAVDAACEANRSAQQGQQVIELSAGEMRKLVARMSSAVPIVEELAKNNGNITEILS
ECCCEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHH
VIEGISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLASRTQSSVGEIRAVIDKVHA
HHHCCCHHCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTQDVVEAIQEGNILANDTALHVQKAVEDLGSIFTSIEAISDMNNQIVRAAEEQQSVSGE
CHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VNQSVVNIRDLSAKILDQAAASEQVGSEIDQLSQQQQKLVNQFKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]